The Warming Arctic: How Thawing Permafrost Challenges Environmental Governance The Warming Arctic: How Thawing Permafrost Challenges Environmental Governance

Witness reports and Iran’s systematic use of punitive psychiatry to undermine dissent contradict government claims that the woman had a mental health crisis and was not protesting enforcement of the country’s mandatory dress code.

La enseñanza bíblica en profundidad de John MacArthur lleva la verdad transformadora de la Palabra de Dios a millones de personas cada día.

La enseñanza bíblica en profundidad de John MacArthur lleva la verdad transformadora de la Palabra de Dios a millones de personas cada día.

La enseñanza bíblica en profundidad de John MacArthur lleva la verdad transformadora de la Palabra de Dios a millones de personas cada día.

La enseñanza bíblica en profundidad de John MacArthur lleva la verdad transformadora de la Palabra de Dios a millones de personas cada día.

The current conflict in the Middle East will leave a lasting environmental impact, prompting calls for urgent restoration and cross-border cooperation.

Israel showcases climate tech at COP29 but misses deeper environmental focus.

Juan López was gunned down on 14 September. An environmental activist, community leader and member of the Municipal Committee in Defence of the Commons and Public Goods of Tocoa, he was the latest victim of extractive greed in Honduras. Communities protecting the rivers that flow through the Bajo Aguán region have seen several of their […]

The right to abortion is a human rights issue that no government agency, courts, local and state legislators, or anyone else has the right to violate or impede in any shape or form. It is a fundamental right that every woman must be free to exercise with impunity, in consultation with her doctor only, who […]

You have undoubtedly heard people say things like, “God is calling me to the mission field,” or “God led me to attend this college,” or “We feel God wants us to get married.” Perhaps you have even said such things yourself. Christians who use expressions like those often mean they have had an impression or a strong feeling that they interpret as a disclosure of the divine will.

Climate change is driving a mental health crisis and accelerating eco-anxiety. Dr. Emma Lawrance is leading Climate Cares, Imperial College London, a centre dedicated to research on climate change in mental health. The researcher spoke to IPS about the need to address this growing concern.

The Asian Development Bank (ADB) has provided loans to financial intermediaries to support projects “whose individual financing requirements are not large enough to warrant the direct supervision of ADB.”

World Mental Health Day is a timely reminder that integrating mental health care into schools, workplaces, and communities is critical for improving health outcomes and reducing costs. Expanding digital interventions and peer-support systems are also crucial, particularly in low- and middle-income countries.

This study finds that investing in sanitation not only improved children’s health, but also created valuable time-savings for all household members.

There are real benefits to a positive mindset, but the idea that we should always look on the bright side has gone too far. Research into toxic positivity can help restore balance

Drugs like Ozempic and Wegovy have unexpected effects on the brain, opening up potential new ways to treat depression, anxiety, addiction and Alzheimer’s

Male pattern baldness could soon be a thing of the past, with new hair loss treatments beginning to show tantalising results

In the quantum realm, a particle’s properties can be separate from the particle itself, including its angular momentum – which could require a rethinking of fundamental laws

Title: Risk for Mental Illness Varies by Gender
Category: Health News
Created: 8/23/2011 11:00:00 AM
Last Editorial Review: 8/23/2011 12:00:00 AM

Title: Mental Skills Decline More Sharply for Women With Alzheimer's: Study
Category: Health News
Created: 8/29/2012 6:05:00 PM
Last Editorial Review: 8/30/2012 12:00:00 AM

Title: Mental and Substance Disorders Major Cause of Nonfatal Illnesses
Category: Health News
Created: 8/28/2013 7:35:00 PM
Last Editorial Review: 8/29/2013 12:00:00 AM

Title: Urine Test May Show Risk of Mental Decline in People With Type 2 Diabetes
Category: Health News
Created: 8/29/2013 5:36:00 PM
Last Editorial Review: 8/30/2013 12:00:00 AM

Title: Experimental Drug Shows Promise for Rare Genetic Disorder
Category: Health News
Created: 8/29/2013 12:35:00 PM
Last Editorial Review: 8/30/2013 12:00:00 AM

Title: Mental Decline a Risk Factor for Stroke, Study Suggests
Category: Health News
Created: 8/25/2014 12:36:00 PM
Last Editorial Review: 8/26/2014 12:00:00 AM

Title: Do Antidepressants in Pregnancy Raise Risks for Mental Woes in Kids?
Category: Health News
Created: 8/27/2014 12:35:00 PM
Last Editorial Review: 8/28/2014 12:00:00 AM

Title: No Mental Benefits Seen for Elderly Who Stop Blood Pressure Meds
Category: Health News
Created: 8/24/2015 12:00:00 AM
Last Editorial Review: 8/25/2015 12:00:00 AM

Title: After Heart Attack, Quitting Smoking Boosts Mental Health, Quality of Life
Category: Health News
Created: 8/25/2015 12:00:00 AM
Last Editorial Review: 8/26/2015 12:00:00 AM

Title: Experimental Drug for Blood Cancer Shows Promise
Category: Health News
Created: 8/26/2015 12:00:00 AM
Last Editorial Review: 8/27/2015 12:00:00 AM

Title: Two Ebola Patients Who Received Experimental Treatment Have Recovered: Congo Officials
Category: Health News
Created: 8/27/2018 12:00:00 AM
Last Editorial Review: 8/27/2018 12:00:00 AM

Title: Soldiers' Suicide Attempts Often Come Without Prior Mental Health Diagnosis
Category: Health News
Created: 8/29/2018 12:00:00 AM
Last Editorial Review: 8/30/2018 12:00:00 AM

Title: Health Tip: Mental Illness Warning Signs
Category: Health News
Created: 8/29/2019 12:00:00 AM
Last Editorial Review: 8/29/2019 12:00:00 AM

Title: A Mentally Challenging Job Could Help Ward Off Dementia
Category: Health News
Created: 8/23/2021 12:00:00 AM
Last Editorial Review: 8/23/2021 12:00:00 AM

Title: Parents, Look Out for Mental Health Issues as College Kids Return to Class
Category: Health News
Created: 8/24/2021 12:00:00 AM
Last Editorial Review: 8/24/2021 12:00:00 AM

Title: Feel Guilty About 'Useless' Leisure Time? Your Mental Health Might Suffer
Category: Health News
Created: 8/26/2021 12:00:00 AM
Last Editorial Review: 8/26/2021 12:00:00 AM

Title: Family History of Mental Illness Ups Odds for Postpartum Depression
Category: Health News
Created: 8/22/2022 12:00:00 AM
Last Editorial Review: 8/23/2022 12:00:00 AM

Title: Mental Health Issues Can Plague Families of Kids With Type 1 Diabetes
Category: Health News
Created: 8/5/2022 12:00:00 AM
Last Editorial Review: 8/5/2022 12:00:00 AM

Title: 'News Addiction' Is Common and Can Harm Your Mental Health
Category: Health News
Created: 8/24/2022 12:00:00 AM
Last Editorial Review: 8/25/2022 12:00:00 AM

Title: Experimental Drug May Ease Hot Flashes
Category: Health News
Created: 6/13/2022 12:00:00 AM
Last Editorial Review: 6/14/2022 12:00:00 AM

Title: Gardening Can Blossom Into Better Mental Health
Category: Health News
Created: 7/11/2022 12:00:00 AM
Last Editorial Review: 7/11/2022 12:00:00 AM

Descriptive statistics (DS) play a crucial role in establishing a solid foundation for study analysis and are important for understanding the results of a study or data set. If the data from DS is used incorrectly, the study may be misinterpreted. Descriptive statistics summarizes and organizes data, making analysis easier and providing an overview of the characteristics of sampled data. This analysis is comprised of measures of central tendency, which includes the mean, median, and mode of a particular data set. Understanding how to use each metric is essential for basic statistical analysis. The purpose of this short report is to review descriptive statistics and describe how to best utilize them during data analysis. The authors aim to provide this short report as an educational resource to assist the dental hygiene research community in understanding statistical analysis through descriptive statistics.

Both preclinical and clinical studies implicate functional impairments of several neuroactive metabolites of the kynurenine pathway (KP), the major degradative cascade of the essential amino acid tryptophan in mammals, in the pathophysiology of neurologic and psychiatric diseases. A number of KP enzymes, such as tryptophan 2,3-dioxygenase (TDO2), indoleamine 2,3-dioxygenases (IDO1 and IDO2), kynurenine aminotransferases (KATs), kynurenine 3-monooxygenase (KMO), 3-hydroxyanthranilic acid oxygenase (3-HAO), and quinolinic acid phosphoribosyltransferase (QPRT), control brain KP metabolism in health and disease and are therefore increasingly considered to be promising targets for the treatment of disorders of the nervous system. Understanding the distribution, cellular expression, and regulation of KP enzymes and KP metabolites in the brain is therefore critical for the conceptualization and implementation of successful therapeutic strategies.

BACKGROUND AND PURPOSE:

Mechanical thrombectomy is a fundamental intervention for acute ischemic stroke treatment. While conventional techniques are effective, cyclic aspiration (CyA) shows potential for better recanalization rates. We aim to investigate factors affecting CyA and compare them with static aspiration (StA).

We identified a de novo heterozygous transient receptor potential cation channel subfamily M (melastatin) member 3 (TRPM3) missense variant, p.(Asn1126Asp), in a patient with developmental delay and manifestations of cerebral palsy (CP) using phenotype-driven prioritization analysis of whole-genome sequencing data with Exomiser. The variant is localized in the functionally important ion transport domain of the TRPM3 protein and predicted to impact the protein structure. Our report adds TRPM3 to the list of Mendelian disease–associated genes that can be associated with CP and provides further evidence for the pathogenicity of the variant p.(Asn1126Asp).

Over the past decades the zebrafish has emerged as an excellent model organism with which to study the biology of all glial cell types in nervous system development, plasticity, and regeneration. In this review, which builds on the earlier work by Lyons and Talbot in 2015, we will summarize how the relative ease to manipulate the zebrafish genome and its suitability for intravital imaging have helped understand principles of glial cell biology with a focus on oligodendrocytes, microglia, and astrocytes. We will highlight recent findings on the diverse properties and functions of these glial cell types in the central nervous system and discuss open questions and future directions of the field.

Most childhood cancers possess distinct clinicopathological profiles from those seen in adulthood, reflecting their divergent mechanisms of carcinogenesis. Rather than depending on the decades-long, stepwise accumulation of changes within a mature cell that defines adult carcinomas, many pediatric malignancies emerge rapidly as the consequence of random errors during development. These errors—whether they be genetic, epigenetic, or microenvironmental—characteristically block maturation, resulting in phenotypically primitive neoplasms. Only an event that falls within a narrow set of spatiotemporal parameters will forge a malignant clone; if it occurs too soon then the event might be lethal, or negatively selected against, while if it is too late or in an incorrectly primed precursor cell then the necessary intracellular conditions for transformation will not be met. The precise characterization of these changes, through the study of normal tissues and tumors from patients and model systems, will be essential if we are to develop new strategies to diagnose, treat, and perhaps even prevent childhood cancer.