BONNEVILLE's SAN FRANCISCO BAY AREA cluster is holding a BAY AREA Food Bank Radiothon on WEDNESDAY (5/6) to benefit six food banks in the region, the ALAMEDA COUNTY COMMUNITY FOOD BANK, … more

ENTERCOM's BOSTON cluster aired a special "Feed NEW ENGLAND Radiothon" on TUESDAY (5/5), raising funding to provide 156,684 meals for people in need through GREATER BOSTON FOOD … more

The RADIO CARES: FEEDING AMERICA EMERGENCY RADIOTHON raised $500,146 for FEEDING AMERICA's COVID-19 hunger relief efforts last THURSDAY (4/30). The daylong event included over 10,000 … more

Investigate the simmering tensions between groups of Australians that led to racially motivated violence at Sydney’s Cronulla Beach in December 2005.

We kicked things off with an update on Rob's marijuana abstaining, or lack thereof. We then spend a good amount...

The post METAL INJECTION LIVECAST #540 - Eight Iota Ripper with Kenny Hickey of SILVERTOMB / TYPE O NEGATIVE appeared first on Metal Injection.

Narrowband internet-of-things (NB-IoT) is a competitive 5G technology for massive machine-type communication scenarios, but meanwhile introduces narrowband interference (NBI) to existing broadband transmission such as the long term evolution (LTE) systems in enhanced mobile broadband (eMBB) scenarios. In order to facilitate the harmonic and fair coexistence in wireless heterogeneous networks, it is important to eliminate NB-IoT interference to LTE systems. In this paper, a novel sparse machine learning based framework and a sparse combinatorial optimization problem is formulated for accurate NBI recovery, which can be efficiently solved using the proposed iterative sparse learning algorithm called sparse cross-entropy minimization (SCEM). To further improve the recovery accuracy and convergence rate, regularization is introduced to the loss function in the enhanced algorithm called regularized SCEM. Moreover, exploiting the spatial correlation of NBI, the framework is extended to multiple-input multiple-output systems. Simulation results demonstrate that the proposed methods are effective in eliminating NB-IoT interference to LTE systems, and significantly outperform the state-of-the-art methods.

The present invention relates to processes for the crystallisation and for the preparation and isolation of a novel crystalline form of fusidic acid, to the use of said processes in the manufacture of pharmaceutical formulation or medicament, and to the use of said crystalline fusidic acid form for the treatment of bacterial infections.

A method of making a metal oxide nanoparticle comprising contacting an aqueous solution of a metal salt with an oxidant. The method is safe, environmentally benign, and uses readily available precursors. The size of the nanoparticles, which can be as small as 1 nm or smaller, can be controlled by selecting appropriate conditions. The method is compatible with biologically derived scaffolds, such as virus particles chosen to bind a desired material. The resulting nanoparticles can be porous and provide advantageous properties as a catalyst.

Provided herein are novel compounds and novel protected compounds that can be derived from polymyxin, including, e.g., polymyxin A. The novel compounds have antibacterial properties against a diverse range of Gram negative bacteria and reduced toxicity compared to polymyxins such as polymyxin A. Also provided are antibacterial pharmaceutical compositions containing the novel compounds and novel protected compounds, as well as methods for preparing the antibacterial compounds and protected compounds.

A method of treating a disease or condition in which up-regulating GAGs is therapeutically beneficial is disclosed, in particular osteoarthritis and skin diseases. The method comprises locally administering to a subject a therapeutically effective amount of an agent capable of down-regulating activity or expression of a component of the renin-angiotensin system.

Provided herein are novel compounds and novel protected compounds that can be derived from polymyxin, including, e.g., polymyxin A. The novel compounds have antibacterial properties against a diverse range of Gram negative bacteria and reduced toxicity compared to polymyxins such as polymyxin A. Also provided are antibacterial pharmaceutical compositions containing the novel compounds and novel protected compounds, as well as methods for preparing the antibacterial compounds and protected compounds.

The disclosure relates to a probiotic delivery system that can be consumed as a snack-food or added to a food product. In particular, the disclosure describes a crisp and tasty treat that comprises viable probiotic microorganisms preserved in a vacuum dried matrix of sugars, proteins, and polysaccharides. The probiotic remain viable within the treat for a longer time without the need for additional moisture barrier coating. The probiotic also remain viable in the animal gastrointestinal tract.

The present invention relates to the generation of a mucin-producing cell using stem/progenitor cells obtained from the amniotic membrane of umbilical cord and therapeutic uses of such mucin-producing cells.

A method of treating an object with radiation that includes generating volumetric image data of an area of interest of an object and emitting a therapeutic radiation beam towards the area of interest of the object in accordance with a reference plan. The method further includes evaluating the volumetric image data and at least one parameter of the therapeutic radiation beam to provide a real-time, on-line or off-line evaluation and on-line or off-line modification of the reference plan.

Systems and methods for use in playing biotic games having a biologically active material as a component. Various games that provide for one or more human players to interact with biologically active materials are disclosed. The game apparatus includes a replaceable cartridge having a chamber in which a biologically active component such as a single-celled organism or a biologically active compound is contained. A stimulus controller accepts instructions from a human user and provides a stimulus to the biologically active component. A response receiver accepts a signal indicative of a response of the biologically active component. A display is provided to display to the user information indicative of the response of the biologically active component, and a game score. A computer-based game controller includes a set of pre-defined rules of play that define a game and that comprise pre-defined rules of scoring for the game.

Non-naturally occurring peptides are provided that act as a Src SH2 domain antagonist of cardiotonic steroids. Pharmaceutical compositions comprising the peptides are also provided along with vectors encoding the peptides. Methods of treating a Src-associated disease and reducing Src activity in a cell are further provided and include administering or contacting a cell with an effective amount of the peptide.

An assay and a method for identifying a prebiotic to treat a subject in need thereof to promote intestinal barrier integrity or to blunt an inflammatory response are provided.

Multi-biotinylated reactants are provided which can be used in divalent complexes for various applications such as colocalization, labeling, immobilization, and purification. Methods for constructing, purifying, and using the bis-biotinylated reactants are also provided. In certain embodiments, two bis-biotinylated reactants are bound to a single streptavidin tetramer to provide a complex having a 1:1 stoichiometry with respect to the bis-biotinylated reactants.

ELLIOT Groves overcame a stamina-sapping schedule to win the Be Wiser Insurance PGA in Hampshire Matchplay final.

Copyright 2018 NPR. To see more, visit SCOTT SIMON, HOST: Finally, time for sports. (SOUNDBITE OF MUSIC) SIMON: The NFL suddenly powered by free agents. Are the Pats running out of gas? And the return of the Tiger (imitating tiger roar). Joined now by NPR sports correspondent Tom Goldman, who's somewhere in Minnesota - actually, Minneapolis. He's pretty easy to find. Tom, thanks so much for being with us. TOM GOLDMAN, BYLINE: Always a pleasure, Scott. How are you? SIMON: I'm fine, thanks. A little over three weeks into the season. Free agents are getting contracts. Among them, let me ask you about safety Eric Reid. This was kind of a surprise, yes. GOLDMAN: Sure is. And it is not just any free agent signing. Eric Reid, former San Francisco teammate of Colin Kaepernick's. He followed Kaepernick's lead and was the second player to take a knee during the national anthem protests. And he also filed a collusion grievance against the NFL, like Kaepernick, after he wasn't signed as a free

Plugin Boutique has launched a sale on the Organetta Kontakt library by AudioThing, featuring the sounds of a small portable reed organ made in the late 50s by the German company Hohner. The sound is generated by an electric fan that blows air into a set of brass reeds hence the sound is reminiscent of […]

The post Save 70% on AudioThing’s Organetta melodica and accordion hybrid appeared first on rekkerd.org.

Far from the World Cup stadium cheers, a prisoner held in Russia is six weeks into a hunger strike.

Reveal host Al Letson talks with Masha Alyokhina, a founding member of the Russian feminist punk rock collective Pussy Riot, about the efforts to free Oleg Sentsov, a Ukrainian filmmaker convicted of an armed plot during Russia’s invasion of Ukraine. He denies any involvement. His supporters fear U.S. President Donald Trump has undermined their cause. Alyokhina knows the topic well: She spent time in prison for challenging Russian President Vladimir Putin, too.

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As always, a big “thank you” to our front-line workers for their selfless, tireless service — and, in this instance, for sharing a hopeful image of the Seattle skyline, shot from West Seattle on a recent morning.

As always, a big “thank you” to our front-line workers for their selfless, tireless service — and, in this instance, for sharing a hopeful image of the Seattle skyline, shot from West Seattle on a recent morning.

As always, a big “thank you” to our front-line workers for their selfless, tireless service — and, in this instance, for sharing a hopeful image of the Seattle skyline, shot from West Seattle on a recent morning.

Het Rode Plein in Moskou blijft vandaag leeg. Geen trots marcherende militairen, geen voorbijtrekkende tanks of luchtafweersystemen, geen veteranen van de Grote Vaderlandse Oorlog. De coronacrisis heeft roet in het eten gegooid.

Het had het hoogtepunt moeten worden van Poetins regeerperiode die in 2000 begon: een grootschalige herdenking van de victorie op nazi-Duitsland, de 75ste Dag van de Overwinning. Maar de grootste militaire parade ooit is de president door de neus geboord.

Lijden en ongekende trots

9 mei is de belangrijkste feestdag in Rusland en dit jaar is een kroonjaar. Het is een dag van rouw om de ruim 20 miljoen doden die de toenmalige Sovjet-Unie aan het eind van de Tweede Wereldoorlog te betreuren had. Maar het is ook een dag van ongekende trots. Al dat lijden heeft immers geresulteerd in de verovering van Berlijn en de val van het nazi-regime in mei 1945. Zonder het bloed, het zweet en de tranen van het Rode Leger en de Sovjet-bevolking als geheel was dat nooit gelukt.

Hoe graag had Poetin niet op het bordes op het Rode Plein gestaan om de militaire parade af te nemen, geflankeerd door wereldleiders aan de ene kant en het handjevol veteranen dat nog leeft aan de andere kant. Bekeken en bewonderd door tientallen miljoenen televisiekijkers.

Een beetje zoals president Loekasjenko van buurland en voormalige Sovjetstaat Wit-Rusland wél deed. Hij vindt het virus een waanvoorstelling:

Politiek patriottisme

De emotie die de Dag van de Overwinning in Rusland oproept is echt, maar Poetin heeft er een element aan toegevoegd: politiek patriottisme. "We hebben geen ander samenbindend idee dan patriottisme," zei hij in 2016.

Een jaar later voegde hij daaraan toe dat het laten varen van patriottisme "heel gevaarlijk is, de eerste stap op weg naar een wereldramp". En tijdens zijn jaarlijkse grote persconferentie van 2019 zei hij: "Naar mijn mening is patriottisme de enig mogelijke ideologie in een moderne democratische samenleving."

De 75ste Dag van de Overwinning zou bij uitstek in het teken moeten staan van dat politieke patriottisme en Poetin zou er het boegbeeld van zijn.

Niet gegund

Poetin vindt dat Russen op zoek moeten naar wat hen bindt: de liefde voor hun vaderland. Het probleem is dat dat zo ongeveer de enige verbindende factor is in Rusland. Op tal van andere terreinen zijn de belangentegenstellingen levensgroot. Een ander probleem is dat Poetin zichzelf als de enig mogelijke leider van dat patriottische Rusland ziet.

Hoe dan ook, zijn finest hour is hem niet gegund. Massabijeenkomsten zijn een ernstig risico voor verdere verspreiding van het coronavirus en het gaat wat dat betreft toch al niet al te best in Rusland. Voor Poetin rest een bijrol die hem maar matig zal bevallen.

Hij legt een krans bij het graf van de onbekende soldaat, hij spreekt het volk toe, misschien zingt hij 's avonds mee als het de bedoeling is dat heel Rusland het beroemde lied Dag van de Overwinning aanheft. En dan rest hem niets meer dan vanuit zijn slaapkamerraam naar het ongetwijfeld majestueuze vuurwerk te kijken.

Shares of Fortress Biotech Inc. (FBIO) are rising over 17% in pre-market today, after the company announced that its partner company Oncogenuity Inc. has entered into an exclusive worldwide licensing agreement with Columbia University to develop novel oligonucleotides for the treatment of genetically driven cancers.

Read the latest on pharma/biotech news, Clinical Trial Results, FDA Calendar, Top Gainers, Recalls, Food Alert and more on RTTNews Biotechnology.

Deploy and extend an Internet of Things (IoT) Connected Vehicle starter kit on IBM Cloud with the Internet of Things Platform and Geospatial services. The starter kit enables you to simulate, view, and manage vehicles driving through a city and set up geofences for notification.

Vinci’s final opera possesses extraordinary energy and some beautiful moments.

Little Rock Marriott giving 163 employees notice of layoffs longer than originally thought.

The post Little Rock Marriott sends notice of extension of layoffs for more than 160 employees appeared first on Arkansas Times.

Perth's heart transplant unit opened for business 25 years ago. Since then almost 200 people have received new hearts.

Recorded less than 60 times worldwide, much remains a mystery about the ornate eagle ray, which boasts leopard-like signature spots and thick black vein-like lines.

A huge amount of viral videos on the net are about animals doing 'stuff', and we 'humans' find that stuff incredibly cute. Is it that we are touched by that part of ourselves within that is animal? Or are we just anthropomorphising animal behaviour and attaching human meaning to it?

Liverpool manager Jurgen Klopp issues a blunt warning to fans trying to shake his hand as Serie A team Juventus reveals a player tests positive for COVID-19.

Making the right choice in life is never straightforward but is one of the main reasons we find ourselves and each other so fascinating. Three Dollars is the story of Eddie Harnovey, a honest, compassionate man with a brilliant wife, Tanya, and a beautiful, if possibly epileptic, daughter Abbey. Eddie's life revolves around work and the three women in his life; the third is Amanda, a childhood sweetheart who re-appears in his life with mathematical precision every nine-and-a-half years. Eddie has a lovely house in the suburbs, he has a strong moral conscience, he's intelligent and witty, and the world around him is falling apart. On the brink of bankruptcy with just $3 to his name, has he made the wrong choices?Perhaps a large part of the answer lies in the speed with which we live our lives. It is easy to feel sympathy for Eddie as he bemoans the pace of change: "Everything happens too quickly to be understood while it is happening. Analysis is impossible until the event is over."A more likely cause of Eddie's predicament may lie in the fact that his wife is about to lose her teaching position at the university and Eddie, an engineer working for the Department of Environment, has been asked by his wife's former lover to falsify a report to allow a smelting plant to be built by Amanda's father.The depth of these relationships is explored with insight and great wit, unpicking those worries that come to us at night while, like Eddie, we lie and notice (and usually ignore) the cracks and flaking of paint on the bedroom ceiling. For Eddie, it is a time to rank debts and what has become the persistence and tyranny of the day-to-day struggle to financially survive.Three Dollars was written in 1998, but set in the times of Australia's introduction to what the surely misnamed 'economic rationalism'. The obsession with material goods and the soulless never-ending pursuit of profit are both a target for Eddie's scorn as well as a source of hilarious black comedy. Written with great humour and prose which at times may seem just a little too deliberate, Three Dollars is as pertinent today as it was in the 1990s.There are times, however, when the characters' tendency to editorialise or sermonise is a touch overwhelming, even if the sentiments seem sound or relevant to Australian politics today. Take this monologue from Eddie's wife, Tanya:"People's fear of change and their despair at the lack of certainty in any area of their lives, particularly where the social and the personal meet, that is with respect to their jobs and income, if it lasts long enough, will lead them to abandon reason, to be suspicious of it and to look for scapegoats and simplistic solutions. The wisdom or correctness of a government's decision will scarcely be discussed but instead attention will be focused on the strength with which the decision was made, the apparent certainty, the conviction with which it was implemented."Admittedly, Tanya is a university politics lecturer, but the moral hectoring in the novel can easily distract from the plot and soon become tiring.Ignoring the occasional sermon, however, Three Dollars an entertaining read, beautifully written and extremely funny. It sat on my bookshelf for over a decade and was rescued only because the mixed reviews for Perlman's latest novel, The Street Sweeper, made me curious. No ambiguity about Three Dollars though: compelling, dramatic and a disconcertingly humorous reflection of the way so many of us live our lives. In 2005, Three Dollars was made into an Australian movie, starring David Wenham. A superb interpretation of the novel, both film and book are highly recommended.

A country football league is moving on from race riots in its community and embracing the AFL's Indigenous round with all five clubs in the small competition to wear specially-designed, Indigenous-themed guernseys.

Camera tapes, used by police to identify Star Hotel rioters 40 years ago, have resurfaced and show that fire hoses were used to subdue the crowds.

A social media video of a tourist hanging off a notorious WA cliff on Easter Sunday has prompted a furious response from a sea rescue group.

As an experiment, David Elliot-Jones went to Japan to make it big. A documentary crew followed him. This is his story.

Writer / director Stephan Elliot on his new 1970s-set film Swinging Safari.

With skin sores, respiratory tract and ear infections and sore throats common in remote Indigenous communities, experts are urging immediate action to combat the rising rates of antibiotic resistance.

Authorities were warned that a teenage boy with severe cognitive impairments was deteriorating in Darwin's Don Dale youth detention centre and needed help, before he joined in on a riot for which he may now go to adult jail.