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Facilitating biomarker development and qualification: Strategies for prioritization, data-sharing, and stakeholder collaboration


Event Information

October 27, 2015
9:00 AM - 5:00 PM EDT

Embassy Suites Convention Center
900 10th St NW
Washington, DC 20001

Strategies for facilitating biomarker development

The emerging field of precision medicine continues to offer hope for improving patient outcomes and accelerating the development of innovative and effective therapies that are tailored to the unique characteristics of each patient. To date, however, progress in the development of precision medicines has been limited due to a lack of reliable biomarkers for many diseases. Biomarkers include any defined characteristic—ranging from blood pressure to gene mutations—that can be used to measure normal biological processes, disease processes, or responses to an exposure or intervention. They can be extremely powerful tools for guiding decision-making in both drug development and clinical practice, but developing enough scientific evidence to support their use requires substantial time and resources, and there are many scientific, regulatory, and logistical challenges that impede progress in this area.

On October 27th, 2015, the Center for Health Policy at The Brookings Institution convened an expert workshop that included leaders from government, industry, academia, and patient advocacy groups to identify and discuss strategies for addressing these challenges. Discussion focused on several key areas: the development of a universal language for biomarker development, strategies for increasing clarity on the various pathways for biomarker development and regulatory acceptance, and approaches to improving collaboration and alignment among the various groups involved in biomarker development, including strategies for increasing data standardization and sharing. The workshop generated numerous policy recommendations for a more cohesive national plan of action to advance precision medicine.  


Event Materials

       




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The gig is unusual because it isn't everyday in our country that the worlds of Indian and western classical music collide on stage. Isbin is one of the world's leading lights in the latter genre. But her introduction to western classical music was wholly by accident. "We were living in Italy for a year when I was nine years old, and my older brother asked for guitar lessons. But he didn't want to study classical. He wanted to be Elvis Presley. So, I volunteered to take his place and raised my hand out of family duty," she reveals, adding that while her father was a nuclear scientist, it was her mother who ensured that she received a solid musical education.

It's a different story for the Bangash brothers, of course. It's almost as if it was preordained that they would take to the sarod, considering that their father, Ustad Amjad Ali Khan, is one of the world's most prolific practitioners of the instrument. But even though they have collaborated with many different musicians — including with Derek Trucks of the rock band Allman Brothers — this is the first time that they will be playing in India with Isbin, who they have known for years.


Ayaan and Amaan Ali Bangash

Ayaan says, "Sharon and we have had mutual admiration for each other's cultures, and I think it's really important to connect with the individual with whom you'll be performing. Also, since we have known each other for a long time, it was easier to develop the music. It's taken us around six years to compose this piece, and I'm glad that everything has fallen into place for us to perform it in India for the first time."

And Isbin adds that her affinity for Indian string instruments began when she was in college. "I loved listening to the sitar, sarod and the tabla back then, and would go to raga concerts because I found them to be meditative. I have also studied transcendental meditation, which of course originated in India, and have been practising it since my teens. That's every single day for many years. So, I have a certain spiritual attraction to the culture and the music here," she says.

Amaan, meanwhile, points out how the sarod and classical guitar have a shared commonality, in that they belong to the larger family of string instruments. Think about it. The guitar, in India, has had a profile that's associated more with jazz, rock 'n' roll and electronic music. Rarely, if ever, has the western classical guitar been heard here in this kind of a collaboration, which also features tabla player Vijay Ghate and mridangam exponent Sridhar Parthasarthy. "We have never played these pieces with a guitar before. But both are string instruments. One is played with the fingertip and the other is played with the finger nails. So, the technical approach isn't wholly different," he tells us, while Ayaan adds that playing this composition will be different for the brothers because they are sticking to a written score.

He further says, "I think everyone's music is a reflection of who they are as individuals. Their soul comes out through their music. And all of us have come out of our comfort zones here to reach a meeting point. Eventually, though, things just happen on stage, you know? You might rehearse all you want, but at the end of the day, what the piece shapes us as is something that has some kind of energy and universal blessing, and we hope to reach that final destination with dignity and grace."

ON February 21, 8 pm
AT Royal Opera House, Girgaum.

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Check out the video of the song below:

Divine refers to it as a small effort from the hip-hop community to support the COVID-19 warriors. The song is supported by The Bill and Melinda Gates Foundation and the ATE Chandra Foundation, who have been working with the government to ensure food and medical aid in the densely populated regions.

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He has met her during the promotions of Panga when he visited the Bigg Boss house. Shehnaaz couldn’t help but cry after meeting him because he reminded her of her home. Jassie Gill was sweet enough to request people to vote for Shehnaaz soon after he met her. Both Shehnaaz Gill and Jassie Gill have a massive fan following respectively and the fans can’t wait to see what’s in store for them.

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The lyrics goes, "So, lock the door and throw out the key / Can't fight this no more, It's just you and me / And there's nothin' I, nothin' I, I can do / I'm stuck with you, stuck with you, stuck with you."

“Grateful to announce that my friend and i have partnered with @1strcf and @sb_projects on this release. proceeds from the streams and sales of #stuckwithu will be donated to first responders children’s foundation to fund grants and scholarships for children of healthcare workers, emergency medical technicians (EMTs), paramedics, police officers and firefighters serving at the front lines during the global pandemic,” Ariana said on her Instagram.

Justin Bieber said in a statement to Just Jared, “More than ever we are seeing the selfless, tireless and amazing work that doctors, nurses, and healthcare providers give to the world every day. It is our hope we can lend our voices to raise awareness and give much-needed support for them and their families. It’s my honor to come together with my friend Ariana and our SB Projects family to try and do some good.”

 

View this post on Instagram

 

2 babies all grown up finally collaborate! Excited for tonight @arianagrande

A post shared by Justin Bieber (@justinbieber) on

Check it out:

ALSO READ: When BTS member Jungkook attended Ariana Grande’s concert during Sweetener tour, watch videos




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