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7 officials to reduce corona doubling rate

In a bid to tackle the spread of coronavirus in a more effective manner, the Brihanmumbai Municipal Corporation has put additional commissioners in charge of seven zones in the city. As per the order, seven additional commissioners will work towards improving the double rate of positive cases from 10 days to 20 days by May 17.




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The Disneyland encyclopedia : the unofficial, unauthorized, and unprecedented history of every land, attraction, restaurant, shop and major event in the original magic kingdom / Chris Strodder ; illustrated maps by Tristan Tang

Strodder, Chris, 1956-




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Commercializing nanomedicine: industrial applications, patents, and ethics / edited by Luca Escoffier, Mario Ganau, Julielynn Wong

Online Resource




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Proof of concept for poor inhibitor binding and efficient formation of covalent adducts of KRASG12C and ARS compounds

Org. Biomol. Chem., 2020, 18,3069-3081
DOI: 10.1039/D0OB00071J, Paper
Maria G. Khrenova, Anna M. Kulakova, Alexander V. Nemukhin
Comprehensive molecular modeling and kinetic analysis reveal a novel mechanism of the inhibition of the oncogenic mutant of the “undruggable” KRAS protein.
The content of this RSS Feed (c) The Royal Society of Chemistry




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Half-sandwich (η5-Cp*)Rh(III) complexes of pyrazolated organo-sulfur/selenium/tellurium ligands: efficient catalysts for base/solvent free C–N coupling of chloroarenes under aerobic conditions

Org. Biomol. Chem., 2020, Advance Article
DOI: 10.1039/D0OB00538J, Paper
Charu Sharma, Avinash Kumar Srivastava, Kamal Nayan Sharma, Raj Kumar Joshi
Three new Rh(III) complexes of organochalcogen (S/Se/Te) ligands were synthesized and along with a co-catalyst Cu(OAc)2, used for the base/solvent free catalysis of Buchwald type C–N coupling of amines and aryl chlorides under aerobic conditions.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry




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Donor–acceptor fluorophores as efficient energy transfer photocatalysts for [2 + 2] photodimerization

Org. Biomol. Chem., 2020, Advance Article
DOI: 10.1039/C9OB02735A, Paper
Qing-An Wu, Feng Chen, Chen-Chao Ren, Xue-Fen Liu, Hao Chen, Liang-Xuan Xu, Xiao-Cong Yu, Shu-Ping Luo
Donor–acceptor fluorophores can act as efficient energy transfer photocatalysts to activate enone substrates, realizing photodimerization and isomerization reaction of enone substrates without precious metal photocatalysts.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry




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Catalyst- and Solvent-Free Efficient Access to N-Alkylated Amines via Reductive Amination using HBPin

Org. Biomol. Chem., 2020, Accepted Manuscript
DOI: 10.1039/D0OB00740D, Communication
ARNAB RIT, Vipin Kumar Pandey, Somnath Bauri
A sustainable approach which works under catalyst- and solvent-free conditions for the synthesis of structurally diverse secondary amines has been uncovered. This one-pot protocol works efficiently at room temperature and...
The content of this RSS Feed (c) The Royal Society of Chemistry




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Protein labeling approach to improve lysosomal targeting and efficacy of antibody–drug conjugates

Org. Biomol. Chem., 2020, 18,3229-3233
DOI: 10.1039/D0OB00265H, Communication
Ying Han, Yifan Da, Mingjia Yu, Yaping Cheng, Xin Wang, Jiale Xiong, Guoying Guo, Yan Li, Xianxing Jiang, Xiaoqing Cai
An anti-EGFR nanobody was labeled at the C-terminus with a lysosome-sorting NPGY (Asn-Pro-Gly-Tyr) motif via sortase-mediated ligation to enhance the clathrin-mediated endocytosis.
The content of this RSS Feed (c) The Royal Society of Chemistry




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Efficient synthesis of a galectin inhibitor clinical candidate (TD139) using a Payne rearrangement/azidation reaction cascade

Org. Biomol. Chem., 2020, Accepted Manuscript
DOI: 10.1039/D0OB00910E, Paper
Jacob St-Gelais, Vincent Denavit, Denis Giguère
Selective galectin inhibitors are valuable research tools and could also be used as drug candidates. In that context, TD139, a thiodigalactoside galectin-3 inhibitor, is currently being evaluated clinically for the...
The content of this RSS Feed (c) The Royal Society of Chemistry




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Officials to pay for illegal building: Venkaiah Naidu

The Centre will push for key reforms including the provision of incentivising civic agencies for good work & making officials concerned accountable for illegal construction or unauthorized development under their jurisdiction.






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[ASAP] Toward Efficient Triple-Junction Polymer Solar Cells through Rational Selection of Middle Cells

ACS Energy Letters
DOI: 10.1021/acsenergylett.0c00857




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Eco-efficient concrete / edited by F. Pacheco-Torgal ... [et al.]

Barker Library - TA439.E36 2013




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Eco-efficient and sustainable concrete incorporating recycled post-consumer and industrial byproducts: held at the ACI Fall 2013 Convention, Phoenix, Arizona, USA, 20-24 October 2013 / Editor: Moncef L. Nehdi

Barker Library - TA441.E286 2013




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‘The borderless Republic’: Sheffield celebrates migration

Britain’s largest festival about refugees and sanctuary is more relevant than ever, writes Lydia Noon.




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The Ultimate Guide to Office Color Psychology

Skillful use of colors in the office can boost your productivity, health, and even happiness. Learn all about color psychology in this article.




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[ASAP] Thioproline Serves as an Efficient Antioxidant Protecting Human Cells from Oxidative Stress and Improves Cell Viability

Chemical Research in Toxicology
DOI: 10.1021/acs.chemrestox.0c00055




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Son, sacrifice, and great shepherd : studies on the Epistle to the Hebrews / edited by David M. Moffitt and Eric F. Mason.

Tübingen : Mohr Siebeck, [2020].




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Most Dangerous Object in the Office: Orion Flare Gun

Wired staffers contemplate resorting to the black powder and strontium nitrate-filled Orion Flare Gun to get their coworkers' attention.




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Most Dangerous Object in the Office: Shomer-Tec Sap Cap

A pound of tiny metal balls hidden inside Shomer-Tec's normal-looking baseball cap turns it into the ultimate stealth cudgel.




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Most Dangerous Object in the Office: GreenSteam Weed Killer

Check out the propane-powered weed killer that blasts 930-degree steam to wipe out most anything in its path.




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Most Dangerous Object in the Office: Mushroom Box Mini Growing System

Check out what happens when you use this DIY kit to grow foodie fungi, or anything else you might want to dream up.




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Most Dangerous Object in the Office: CRY-AC-3 Liquid Nitrogen Dispenser

Fill the CRY-AC-3's canister with liquid nitrogen and pull the trigger. Then just chill.




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Most Dangerous Object in the Office: Superior Hiwheel Bicycle

Nobody said going retro would be safe. Check out Rideable Bicycle Replicas' 4-foot-high bike, which we've been careering around the office hallways.




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Most Dangerous Object in the Office: Garden Games Outdoor Darts

Outdoor Darts isn't for the faint of heart.




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Most Dangerous Object in the Office: FlashFog Tiger 1500 X2 Fog Generator

A killer party or a killer instinct? A blanket of fog and blinding strobe lights await thieves caught by FlashFog's Tiger.




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Most Dangerous Object in the Office: Supreme Products Pocket Chain Saw

Set the office a-chattering when you whip out this 4-ounce human-powered chain saw. Then set that leg on your office chair straight.




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Most Dangerous Object in the Office: Lee Production Pot IV Electric Melter

Some people use the Lee Production Pot metal melter to make bullets. Wired's editors are pleased with their hand-forged paper clips.




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Most Dangerous Object in the Office: Cyborg Crampons

These stainless steel cleats will will grip rock, ice, particleboard—whatever cubicle wall that blocks your path.




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Most Dangerous Object in the Office: Mo-Tool Ax

Brook & Hunter’s Mo-Tool is quite a monstrosity, but you can’t frown on it forever -- it has an ax!




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Most Dangerous Object in the Office: AeroShot Pure Energy

A quick powdery blast of vitamin B, niacin, and caffeine courtesy of Breathable Foods could be just the (legal) pick-me-up you need.




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Most Dangerous Object in the Office: Pocket Artillery Mini Cannon

Check out the Pocket Artillery Mini Cannon in action.




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Most Dangerous Object in the Office: North Face Avalanche Airbag Safety System Backpack

No matter the danger&mash;a torrent of gizmos or an avalanche of snow—this North Face system will have your back (Saint Bernard and brandy not included).




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20.06 Most Dangerous Object in the Office: Wicked Lasers Torch

20.06 Most Dangerous Object in the Office: Wicked Lasers Torch. Let's Burn Ants! (No animals were harmed in the making of this video; humans however, were)




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Most Dangerous Object in the Office: Ara Safety Pro

The Ara Safety Pro is like the do-gooder offspring of a fire extinguisher and a smoke grenade. Just pull the pin and toss the 9-pound projectile directly into the blaze.




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Most Dangerous Object in the Office: Solowheel Motorized Unicycle

Check out the Solowheel Motorized Unicycle in action.




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Most Dangerous Object in the Office: Skike VX Twin Roller Skis

Finally, skiing minus all that cold wet snow. With inflatable tires, elaborately adjustable bindings that allow your heels to lift, and optional ski-style poles, Skikes let you replicate cross-country skiing without going outside.




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WIRED Live - Creating Video Games That Are Easy to Learn, but Difficult to Master

Atari founder Nolan Bushnell and game developer Dong Nguyen join author David Kushner to talk about the ingredients for a successful video game and how the industry has transitioned from being a hobby to a full-blown business.




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Angry Nerd - Will the New U.K. Import “Gracepoint" Join the Ranks of “The Office,” “House of Cards,” and “Shameless”?

The British are coming. Can the new crime drama Gracepoint (based on the U.K. hit Broadchurch) find success stateside and join the shortlist of Brit expats that found their footing on red, white, and blue T.V.s, like The Office, House of Cards, and Shameless?




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Out of Office with Brent Rose - What $500 Can Get You on Magic (Silicon Valley’s Newest Texting-Based Delivery Service)

We gave tech writer Brent Rose $500 to stress-test Silicon Valley’s overnight sensation, Magic. From meatballs to medicinal cannabis to Mexican wrestling, see what unfolds when he pushes the new text message-based delivery service.




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Out of Office with Brent Rose - Fitness Trackers vs. Smartphones: Why Wearables Win

Tech writer Brent Rose debunks a study claiming smartphones are as good as wearables at tracking activity. From the Fitbit Charge HR to the iPhone 6, Brent's stress tests uncover compelling results that demonstrate why wearables with heart rate monitors win.




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Out of Office with Brent Rose - Tesla’s Powerwall Home Battery: The Stuff Worth Knowing

Elon Musk recently unveiled Tesla Energy and the Powerwall home battery. I'll attempt to cut through the hype and break down the basics. NOTE: One of the most important things we neglected to mention in the video is that a big part of the appeal for this system is not economical, but environmental. It may not be easier on the wallet (at least not yet) but you're powering your home with green energy instead of fossil fuels, and there's a lot to be said for that. -Brent




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Out of Office with Brent Rose - Fun With Powdered Alcohol: You Can Stop Being Scared Now

People are freaking out about powdered alcohol, but I wasn’t convinced they understood the science behind it. So I tested their concerns. Will it get you crazy drunk? Will people snort it? Watch & see! -Brent




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I Made an Untraceable AR-15 'Ghost Gun' In My Office

WIRED senior writer Andy Greenberg puts new homemade gunsmithing tools to the test as he tries three ways of building an untraceable AR-15 semi-automatic rifle---a so-called "ghost gun"---while skirting all gun control laws.




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Out of Office with Brent Rose - Best & Worst Foods for California’s Drought

California is in an unprecedented drought, but you gotta eat, right? Well, some foods use way more water than others. We chewed through a ton of data to make this bite-sized video. For you! -Brent




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Unnecessarily Rushed Explanations - The Most Difficult Video Game of All Time: Super Hexagon

Super Hexagon is not a video game for the easily discouraged. You die early and often until eventually (hopefully) you get into the swing of things. WIRED editor Chris Kohler explains why it’s the most difficult video game of all time.




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Out of Office with Brent Rose - Mini GoPro! Hero4 Session: Full Review, Tests, Comparison Footage

If you hate GoPro's rectangular shape, your prayers have been answered! Sort of. We took the new Hero4 Session into rivers, lakes, and surf, off cliffs and platforms, through trees and go kart courses. Our full review will tell you everything you need to know.




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Out of Office with Brent Rose - Rideables Are So Hot Right Now. We Put Them to the Test

Electric personal transportation devices (aka “rideables”) are everywhere. We’re seeing them under everyone from Justin Bieber to J.R. Smith to Casey Neistat, but are any of them worth a damn? We put four of the most promising rideables to the test and I’ve got the scars to prove it. -Brent




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Out of Office with Brent Rose - Teched-Out Van

Brent Rose has just taken “Out of Office” to the next level. In this episode, he shows off the teched-out van he will be living in during his nascent year-long road trip across the United States. Brent gives us a fun tour of his supremely techy mobile home, including the roof-mounted solar panels, cutting edge lithium ion batteries, GPS-enabled, smartphone-connected alarm system, fingerprint-secured safe, and cutting edge stereo system.