A previously healthy 9-year-old immigrant girl from Mexico was evaluated in the emergency department (ED) with one week of fatigue, fevers, rhinorrhea, and cough. She initially presented to her primary pediatrician, where a complete blood count revealed neutropenia, prompting referral to the ED. In the ED, she was found to be influenza A–positive. Because of dehydration, she received intravenous fluids and was admitted to the pediatric hospital medicine service. After 2 days, influenza symptoms improved, and oral intake increased. However, she was noted to have decreased bilateral lower-extremity strength, absent Achilles reflexes, decreased lower-extremity sensation and proprioception, a positive result on the Romberg sign, and abnormal heel-to-shin testing results. These findings prompted an urgent neurology consultation. After extensive imaging, laboratory evaluation, and further consultations, a diagnosis was established.

Bus4Life is OM’s mobile missions centre to the unreached people of Central and Eastern Europe, bringing books and also participating in summer programmes, as it did in summer 2017.

LEARNING from the hands of her grandmother in Italy, it was perhaps always going to be Giovanna Eusebi's destiny that she would go on to create culinary masterpieces of her own one day.

Grab a refurbished third-generation iPad Air or fifth-generation iPad Mini from Apple to save big while getting nearly the same experience new tablets offer.

The Pennsylvania Technical Assistance Program (PennTAP) at Penn State is looking for undergraduate entrepreneurs from any Penn State campus to compete in the 2020 Inc.U Competition. Six finalist teams will earn a spot on “The Investment,” a production of WPSU-TV, giving them a chance to pitch their company for a share of $30,000 in funding. The 2020 Inc.U Competition submission deadline is Feb. 7.

Eurostar says all its passengers must wear face masks as a safeguard against Covid-19, effective from Monday.

Three new studies show that a web of factors appear to influence how often black and Hispanic children are identified for special education compared to similar white peers.

Eoin Hayes's first-half strike earned the Group B points for Irish side Region 2 as Russia's South Region failed to convert their possession into a single shot on goal.

The only way an ed-tech company can have a meaningful impact in schools is by addressing a specific problem and offering a real solution.

The Florida Department of Education is in a bitter dispute with a software company it hired to create online resources aligned with the standards for teachers and students.

Rural advocates say developing youth entrepreneurs is one way to spark economic development, and a new Rural Entrepreneurship Teaching Unit gives educators a template for teaching students about that issue.

Yong Zhao speaks to BookMarks about the new education paradigm that he proposes in World Class Leaders (Corwin, 2012).

At age 17, Nick D'Aloisio just sold Summly to Yahoo! for $30 Million. With technology increasingly penetrating our everyday lives, today's children grow up with computers in their blood: thus, this rise of the teenage entrepreneur is not fading anytime soon.

Entrepreneurship education should be universally available, to provide all students with opportunities to explore and fulfill their potential, write Stephanie Bell-Rose and Thomas W. Payzant.

Entrepreneurship is a powerful tool that can be used within an established institution to foster innovation and accelerate promising initiatives. Leading a startup project within an organization is called "intrapreneurship" and there are many ways to do that within a school setting.

While ed-tech entrepreneurship may be less risky than other sectors, there are still many uncertainties to be aware of. Financial, technology, and market sectors are all areas for deep thought and caution.

Many programs designed by educational entrepreneurs are rendered ineffective by complications with current public policy, suggests a report published by the National Center for the Study of Privatization in Education at Teachers College, Columbia University.

K-12 educational entrepreneurship today is marked by at least three major tensions that deserve a lot more careful attention.

What does it take to get students interested in learning entrepreneurial skills?

There are many entrepreneurs who can claim that "they've always known they would start their own business," but I am not one of them. So how did I end up as an entrepreneur writing this blog?

Entrepreneurship is often considered a "risky" endeavor. But I think ed-tech startups are often less risky that startups in other industries.

By providing authentic opportunities to practice self-direction, connect with the larger community, collaborate with peers, and develop their respect for social responsibility, the annual Magnolia Makers Market is one way Montessori For All works toward preparing children to be successful leaders in

Rudy Gay's Flight 22 Foundation is partnering with ed-tech company EverFi to teach students how to create a successful business.

In the possible coming of Article 11 and Article 13 to law in the European Union, some see disaster for the internet. What's really happening is an attempt to legally extort money out of Google, Facebook, and other far-too-successful US-based mega-corporations.

For three decades now, the artist and playwright John Byrne has been sitting regularly for photographer David Eustace, the Glasgow-born photographer who left school at 16 and joined first the navy and then the prison service before settling on a career behind a camera.

UEFA Grassroots Day has been marked in Munich and all over Europe with a series of especially arranged activities promoting the message that football is open to everyone.

UEFA's technical team of experienced trainers will look at the trends and talking points at UEFA EURO 2012 from a coaching point of view, helping to produce a report on the tournament.

Youngsters in Northern Ireland celebrated UEFA EURO 2012 with a specially-themed event for UEFA Grassroots Day, one of several activities arranged across the country.

Source: Retema - La Comisión Europea ha aprobado un conjunto de inversiones por valor de 222 millones de euros procedentes del presupuesto de la UE para facilitar la transición de Europa hacia un futuro más sostenible e hipocarbónico en el marco del programa LIFE de medio ambiente y acción por el clima. La financiación de la UE movilizará inversiones adicionales con las que se llegará a un total de 379 millones de euros destinados a 139 nuevos proyectos en 20 Estados miembros.

Febrile neutropenia is a common complication in children with cancer. Traditionally, even low-risk episodes have been managed entirely in an inpatient setting, and discharge of the patients has been delayed until resolution of fever and sustainable hematopoietic recovery.

The results of this decision-analytic model evaluating low-risk febrile neutropenia episodes suggest that the substantially higher costs of inpatient management cannot be justified on the basis of safety and efficacy considerations or patient/parent preferences. Uncertainty remains whether intravenous or oral treatment might be the preferable route of drug administration in an ambulatory setting. (Read the full article)

Corticosteroids inhibit the expression of many proinflammatory cytokines released during the course of community-acquired pneumonia infection. Corticosteroids have been found in some studies to be associated with improved clinical outcomes in adults with pneumonia. No studies have investigated corticosteroid use in children with pneumonia.

Results showed that corticosteroid treatment in children with pneumonia is common and its use is highly variable across institutions. Although corticosteroid therapy may benefit children with acute wheezing treated with β-agonists, corticosteroid therapy may lead to worse outcomes for children without wheezing. (Read the full article)

Neurocognitive testing is recommended for the assessment of sport-related concussions. Computerized neurocognitive tests are more sensitive and more efficient than traditional neuropsychological testing in assessing sport-related concussions.

We describe the current prevalence of computerized neurocognitive testing, the relative use of the various computerized programs, the types of clinicians interpreting test scores, and associations of computerized tests with timing of return-to-play and medical provider type managing the athlete. (Read the full article)

Very low birth weight (VLBW) male neonates appear to have increased mortality. VLBW female neonates appear to have better long-term outcomes.

VLBW male neonates have increased mortality and poorer neurological outcome. This gender difference appears to disappear at weeks' gestation. (Read the full article)

Pertussis is a poorly controlled vaccine-preventable disease. Verifying outbreaks is challenging owing to nonspecific clinical presentations and imperfect diagnostic tests. Exclusive reliance on highly sensitive polymerase chain reaction has been associated with pseudo-outbreaks.

Contamination of specimens with vaccine derived Bordetella pertussis DNA from pediatric clinic surfaces likely resulted in misdiagnoses. Standard practices, liquid transport medium, and lack of polymerase chain reaction cutoffs for discerning weakly positive (contaminant) DNA are contributory, but modifiable factors. (Read the full article)

Vitamin D levels in the general population have decreased considerably over the past decade. The implications of maternal vitamin D insufficiency during pregnancy for offspring neurocognitive development remain unclear.

Studying a large sample and using a prospective longitudinal design, this study demonstrates a link between maternal vitamin D insufficiency during pregnancy and offspring language impairment. There was no association with childhood behavioral or emotional problems. (Read the full article)

Community-acquired pneumonia (CAP) is a common pediatric illness caused by Streptococcus pneumoniae. New pediatric Infectious Diseases Society of America CAP guidelines are now available recommending ampicillin as empirical treatment of children hospitalized with uncomplicated CAP.

This study found that a CAP guideline led to an increase in the narrow-spectrum antibiotic ampicillin. Additionally, an increase in the use of amoxicillin at discharge was observed. Furthermore, change in therapy did not lead to increased adverse outcomes. (Read the full article)

Some studies reveal an association between exposure to alcohol consumption in movies and youth drinking, but the evidence is sparse.

Exposure to alcohol consumption in movies is associated with youth binge drinking, is little influenced by cultural differences between countries (Germany, Iceland, Italy, Netherlands, Poland, and Scotland), and is specific to movie alcohol, not movie smoking, depictions. (Read the full article)

Pneumonia is still a significant problem in young children from developing countries where zinc deficiency is prevalent. Although zinc supplementation reduces the risk of childhood pneumonia, the effect of adjunct zinc on severe pneumonia is unclear with conflicting results.

The overall effect, if any, of zinc as adjuvant therapy for World Health Organization–defined severe pneumonia in young children is small. (Read the full article)

There is a perception among clinicians that methicillin-resistant Staphylococcus aureus (MRSA) bacteremia and/or meningitis result in a greater burden of disease than invasive infections attributed to methicillin-susceptible Staphylococcus aureus (MSSA) among very low birth weight (VLBW) infants.

VLBW infants with MRSA and MSSA bacteremia and/or meningitis have equivalent morbidity and mortality. These findings suggest that allocation of resources for prevention and treatment of both MRSA and MSSA infections among VLBW infants should be comparable. (Read the full article)

Staphylococcus aureus is a leading cause of infections in infants. Staphylococcal colonization is a known risk factor for infection, but whether maternal colonization plays a role in subsequent colonization in the infant is unclear.

This prospective study found that infants born to women colonized with S aureus either during their third trimester of pregnancy or at the time of delivery are more likely to harbor S aureus than are those born to noncolonized women. (Read the full article)

Although developmental care in NICUs reduces the stress experienced by preterm infants, the actual level of developmental care may vary and little is known about how the level of developmental care relates to preterm infants’ neurobehavioral performance.

The study demonstrates the relationship between variations in developmental care in NICUs and the neurobehavior of preterm infants. Infants from NICUs with high-quality developmental care compared with infants from units with low quality of care evidenced a better neurobehavioral profile. (Read the full article)

Diabetes during pregnancy has been associated with general development impairments in offspring; however, associations between autism and maternal diabetes have been inconsistent. Few studies have examined related conditions accompanied by underlying increased insulin resistance and their association with developmental outcomes.

This population-based study in young children provides evidence that maternal metabolic conditions are a risk factor for autism, developmental delay without autistic symptoms, and impairments in several domains of development, particularly expressive language, after adjusting for sociodemographic and other characteristics. (Read the full article)

Isolated methylmalonic acidemia, one of the most common inborn errors of organic acid metabolism, is known to be associated with variably impaired intellectual functioning and severe biochemical and clinical abnormalities. However, the neurocognitive outcomes have yet to be fully described.

This research defines the neurocognitive phenotype of isolated methylmalonic acidemia and identifies processing speed as a specific impairment. Clinical, biochemical, and molecular genetic covariates were explored. A history of hyperammonemia at diagnosis was found to correlate with poorer cognitive outcomes. (Read the full article)

Persistent facial nerve palsy is a well-described neurologic deficit after Lyme neuroborreliosis and occurs in 13% to 20% of children. Other neurologic deficits are less closely described. Nonspecific subjective symptoms are reported as often among patients as controls in previous short-term follow-up studies.

Persistent neurologic deficits, other than facial nerve palsy, were found in 14% of patients, causing impaired fine motor skills, poor balance, or persistent pain. Nonspecific subjective symptoms were reported as often among patients as controls in this long-term follow-up study and should not be considered as sequelae after Lyme neuroborreliosis. (Read the full article)

The 2009 influenza A (H1N1) pandemic caused illness in all age groups, but children were disproportionately affected. Children with underlying neurologic disorders were at high risk of influenza-related complications, including death.

This study provides the first detailed description of underlying neurologic disorders among children who died of influenza A (H1N1)pdm09 virus infection. (Read the full article)

Previous studies suggest that abnormal findings on conventional EEG during the neonatal period are associated with death or severe brain injury in preterm infants. However, large cohort studies on preterm EEG for predicting later neurodevelopmental outcome remain scarce.

This study demonstrates precise prognostic values of conventional EEG for predicting neurodevelopmental outcome in the current perinatal care setting. Additionally, its prognostic values are independent of severe injury on neuroimaging and clinical risk factors. (Read the full article)

Infants with hypoxic-ischemic encephalopathy suffer a high rate (>40%) of death or moderate to severe disability, even after therapeutic hypothermia. High-dose erythropoietin (Epo) reduces brain injury and improves neurologic function in animal models of neonatal hypoxic-ischemic brain injury.

Multiple doses of Epo (up to 2500 U/kg intravenously) given in conjunction with hypothermia are well tolerated in newborns with HIE. Epo doses of 1000 U/kg intravenously in cooled infants produce plasma concentrations that are neuroprotective in animal studies. (Read the full article)

Adult patients with neurocardiogenic syncope have shown high rates of depression. Patients with more severe depressive symptoms have higher rates of syncope recurrence. Psychiatric interventions improve quality of life and decrease syncope recurrence rates.

Children with neurocargiogenic syncope presented a 2.6-fold higher rate of clinically significant depressive symptoms compared to healthy controls. No recurrent syncope was noted during follow-up which along with improvement in family functioning predicted depressive symptoms improvement. (Read the full article)

There are limited data on current testing and treatment patterns for children hospitalized with pneumonia, and on whether institutional guidelines affect care.

The use of institutional clinical practice guidelines was not associated with changes in diagnostic testing, hospital length of stay, or costs for children hospitalized with pneumonia, but was associated with increased use of narrow-spectrum antibiotics. (Read the full article)