NEW CASTLE (May 15, 2018) – Governor John Carney will present the Governor’s Youth Volunteer Service Awards to eight young people and six groups during a May 24 ceremony in recognition of their service to Delaware. “Through their volunteer efforts, these young people are making a lasting impact on their communities and the lives of […]

NEW CASTLE (May 8, 2019) – Highlighting the difference that young volunteers make in their communities, Governor John Carney will present the Governor’s Youth Volunteer Service Awards to 25 individuals and three groups during a May 14 ceremony in recognition of their service to Delaware. “Giving back to our communities is one of the most […]

Nominate a young person making a difference through volunteerism in Delaware.

The plot continues to thicken around Realme's seemingly never-ending stream of new devices. Last month, a certain RMX2142 appeared on Chinese certification authority TENAA's website. Now, the very numerically-similar RMX2141 and the RMX2052 have joined its ranks. RMX2142 There are more than a few similarities between these devices, as listed by TENAA. All of them seem to have the exact same dimensions of 163.8 x 75.8 x 8.9mm, which, coincidentally, or rather not, match-up perfectly with the existing Realme X50m 5G. Same goes for the reported weight of the RMX2142 and the...

(LAWRENCE KS) As the sun set Saturday over Memorial Field, the Indians and Bacone College kicked off game four of Haskell Football's season. Athletes and fans were pulling for a win against our rival Warriors. The Indians came out hard and fought endlessly through the night, but in the end, it would be experience that would win the game.

Wearing delicate makeup, a traditional hairstyle and the ancient Chinese clothing Hanfu, a young lady posed for a vintage photoshoot.

The youth unemployment rate has hit a record-high level in August since the Asian financial crisis. As for the number of net job increase, it fell to a low of 54 months. Even though the government is doing everything it can to create jobs, jobs-related figures won't budge. According to a report "August 2017 Employment Trend" published by the National Statistical Office on September 13, the jobless ratio of those aged between 15 and 29 was 9.4 percent, up 0.1 percentage point from a year ago. ...

Patna: Tales of humanity and brotherhood have brought much-needed comfort to the people in distress as they battle the coronavirus pandemic, locking themselves in homes for the past 40 days. Two such incidents in four days stand out. A man from the Indian state of Bihar broke his fast to donate blood in a bid to save the life of a little girl admitted to a government hospital. The...

Nteranya Sanginga is Director General of the International Institute of Tropical Agriculture

The post Pandemic Lays Bare Africa’s Deficits, but Youth Will Grow the Future appeared first on Inter Press Service.

80 young African scholars are tackling the business of agriculture through the innovativeness and freshness that comes with youth — while obtaining their masters or doctoral degrees in the process.

The post Africa’s Youth Scholars Harvest Ideas on the Business of Agriculture appeared first on Inter Press Service.

Vanessa Nakate of Uganda may have been cropped out of a photograph taken at the World Economic Forum, but she along with Swedish activist Greta Thunberg have made the climate crisis centre stage. Women Deliver Young Leader Jyotir Nisha discusses with Costa Rican President Carlos Alvarado Quesada on how to harness young people to overcome […]

The post Harness Youth to Change World’s Future appeared first on Inter Press Service.

The mining sector in Africa is facing radical change as youth activists take action against the environmental degradation caused by mining industries. Tensions between activists and the mining industry have raised, however, concerns over human rights abuses. Kenya’s National Coalition for Human Rights Defenders reported, for instance, cases of harassment and intimidation “against at least […]

The post Growing Youth Activism for Environmental Protection in Africa appeared first on Inter Press Service.

As social distancing, quarantines and lockdowns have spread across the globe to slow the spread of coronavirus, they have imposed some of the greatest worldwide restrictions on public gatherings in living memory. These restrictions may be necessary for public health, but they require the most anxious scrutiny to prevent them being misused to quash legitimate political […]

The post How Coronavirus Makes us Rethink Youth Protests appeared first on Inter Press Service.

A group of irate youths got their lives handed to them when they attempted to block Deputy President William Ruto’s bloackade.

To reduce air pollution, national and city government policy makers, their development partners, academe, and the private sector need to work with young people. 

BENGALURU, INDIA –  HARMAN (NYSE:HAR), the premier connected technologies company for automotive, consumer and enterprise markets, today announced that it has launched its global corporate social responsibility initiative, ‘HARMAN Inspired’, in India....

Stone by stone, digital artists and game developers from Mosul are rebuilding Nineveh's heritage sites in the digital world. Francis Maguire reports.

Young German climate-strikers on Friday (April 24) got creative with their social distancing, set up hundreds of cardboard cutouts to represent protesters taking part in the Fridays for Future demonstration.

Stone by stone, digital artists and game developers from Mosul are rebuilding Nineveh's heritage sites in the digital world. Francis Maguire reports.

Stone by stone, digital artists and game developers from Mosul are rebuilding Nineveh's heritage sites in the digital world. Francis Maguire reports.

Title: U.S. Youth Suicide Rates Hit 19-Year High After '13 Reasons Why'
Category: Health News
Created: 4/30/2019 12:00:00 AM
Last Editorial Review: 4/30/2019 12:00:00 AM

Identifying gene variants causing monogenic diabetes (MD) increases understanding of disease etiology and allows for implementation of precision therapy to improve metabolic control and quality of life. Here, we aimed to assess the prevalence of MD in youth with diabetes in Lithuania, uncover potential diabetes-related gene variants, and prospectively introduce precision treatment. First, we assessed all pediatric and most young-adult patients with diabetes in Lithuania (n = 1,209) for diabetes-related autoimmune antibodies. We then screened all antibody-negative patients (n = 153) using targeted high-throughput sequencing of >300 potential candidate genes. In this group, 40.7% had MD, with the highest percentage (100%) in infants (diagnosis at ages 0–12 months), followed by those diagnosed at ages >1–18 years (40.3%) and >18–25 years (22.2%). The overall prevalence of MD in youth with diabetes in Lithuania was 3.5% (1.9% for GCK diabetes, 0.7% for HNF1A, 0.2% for HNF4A and ABCC8, 0.3% for KCNJ11, and 0.1% for INS). Furthermore, we identified likely pathogenic variants in 11 additional genes. Microvascular complications were present in 26% of those with MD. Prospective treatment change was successful in >50% of eligible candidates, with C-peptide >252 pmol/L emerging as the best prognostic factor.

Abnormal interactions between misfolded mutant and wild-type (WT) proinsulin (PI) in the endoplasmic reticulum (ER) drive the molecular pathogenesis of mutant INS gene–induced diabetes of youth (MIDY). How these abnormal interactions are initiated remains unknown. Normally, PI-WT dimerizes in the ER. Here, we suggest that the normal PI-PI contact surface, involving the B-chain, contributes to dominant-negative effects of misfolded MIDY mutants. Specifically, we find that PI B-chain tyrosine-16 (Tyr-B16), which is a key residue in normal PI dimerization, helps confer dominant-negative behavior of MIDY mutant PI-C(A7)Y. Substitutions of Tyr-B16 with either Ala, Asp, or Pro in PI-C(A7)Y decrease the abnormal interactions between the MIDY mutant and PI-WT, rescuing PI-WT export, limiting ER stress, and increasing insulin production in β-cells and human islets. This study reveals the first evidence indicating that noncovalent PI-PI contact initiates dominant-negative behavior of misfolded PI, pointing to a novel therapeutic target to enhance PI-WT export and increase insulin production.

Moe responded to reports that some young people are congregating and spreading COVID-19 in La Loche, the centre of an outbreak that's still driving the overwhelming majority of new cases in Saskatchewan.

Lokomotiv Moscow youth player Innokenty Samokhvalov has died at the age of 22 after suffering suspected heart failure while training.

Iain Brunskill should currently be getting his teeth into an exciting new role with the Chinese FA.

Manchester United are waiting to learn the fate of the FA Youth Cup after the academy season was cancelled due to coronavirus.

Marcus Rashford has urged Manchester United's academy starlets to stay positive and 'remember why they fell in love with football' after their season was cut short because of the coronavirus outbreak.

The first ever set of specific recommendations to support transgender autistic young people was co-created by these youth and their families working hand-in-hand with clinical experts. The resulting model offers clinicians a set of concrete ways to provide this unique population the support they need.

But if he wants to avoid being the target of their protests both before and—if he’s elected—after November, he’ll need to earn more than just their votes.

"We simply cannot stand for an epidemic of violence that robs our youth of their childhood and perpetuates a cycle in which today’s victims become tomorrow’s criminals."

“We must engage the broadest spectrum of community partners in order to stem youth violence, and a cornerstone of that partnership is young people themselves,” said Attorney General Holder. “The Department of Justice is committed to working with young people to develop innovative solutions to help prevent teen dating abuse.”

The plain truth is that youth violence is far-too common. There’s no single cause and no simple solution. But we know one important contributor is the absence of a responsible, loving father. Here in D.C., where half of African-American households don’t include even one grown man, the implications of this fact could not be clearer.

At the direction of President Obama, the Departments of Justice and Education officially launched the National Forum on Youth Violence Prevention (the forum) along with participating localities and other federal agencies.

Attorney General Eric Holder today commended teams from six cities across the country for developing comprehensive plans to reduce youth violence in their communities.

"This gathering marks an important step forward in what I know – and what I pledge – will be an ongoing conversation about how we can address violence among – and directed toward – our nation’s young people."

“This conference provides a critical opportunity to highlight, to celebrate, and – hopefully – to replicate, the extraordinary progress that’s been made under Minneapolis’s “Blueprint for Action” strategy. It’s also our chance to reaffirm our commitment to the goals that we share – protecting young people in need and at risk; and strengthening our approach to addressing one of the greatest public safety – and public health – epidemics of our time: children’s exposure to violence.”

The operator of Morning Star Center, a residential facility located in Port-au-Prince, Haiti, that provided food and shelter to minors, has been charged with offenses involving the sexual abuse of minors in Haiti.

"You are here today because you know how important it is to continue finding innovative and effective ways to fight violent crime. As someone who focuses on criminal prosecution, I am absolutely committed to doing everything I can to help make our communities safer."

One hundred and seventy five young men and women from nearly 50 tribal communities across the country have convened at the week-long 2011 National Intertribal Youth Summit in Santa Fe, N.M., which runs from July 24-28, 2011.

“The work we are doing is sending an unmistakable message: that, in this country, we will not give up on our children when it comes to combating youth violence,” Attorney General Eric Holder said.

Following a comprehensive investigation, the Justice Department announced today its findings that the state of Mississippi violated the constitutional rights of youth detained at the Walnut Grove Youth Correctional Facility.

Universal Health Services Inc. (UHS) and two subsidiaries have reached a settlement in a False Claims Act lawsuit with the United States and the Commonwealth of Virginia, the Justice Department announced today.

Attorney General Eric Holder today recognized six cities for their progress in preventing youth violence at the second annual summit of the National Forum on Youth Violence Prevention held in Washington, D.C.

"I don’t need to tell anyone here what a difficult challenge youth violence is. You’re all part of the Forum because you’ve seen the consequences of juvenile crime in your own communities. You understand how complex this issue is – and you know this is not a problem any of us can solve alone – especially in this tough fiscal climate," said Acting Assistant Attorney General Leary.

"Especially in recent weeks – as the importance of protecting our children from harm has been at the forefront of our national discourse – the urgency of this challenge has been brought into stark focus. And the need to take action has never been more clear," said Attorney General Holder.