Protein crystallography is an established method to study the atomic structures of macromolecules and their complexes. A prerequisite for successful structure determination is diffraction-quality crystals, which may require extensive optimization of both the protein and the conditions, and hence projects can stretch over an extended period, with multiple users being involved. The workflow from crystallization and crystal treatment to deposition and publication is well defined, and therefore an electronic laboratory information management system (LIMS) is well suited to management of the data. Completion of the project requires key information on all the steps being available and this information should also be made available according to the FAIR principles. As crystallized samples are typically shipped between facilities, a key feature to be captured in the LIMS is the exchange of metadata between the crystallization facility of the home laboratory and, for example, synchrotron facilities. On completion, structures are deposited in the Protein Data Bank (PDB) and the LIMS can include the PDB code in its database, completing the chain of custody from crystallization to structure deposition and publication. A LIMS designed for macromolecular crystallography, IceBear, is available as a standalone installation and as a hosted service, and the implementation of key features for the capture of metadata in IceBear is discussed as an example.

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The pandemic has once again felled Burning Man. Some burners still plan to gather for informal events on the dusty Black Rock Desert Playa this summer.; Credit: Bernard Friel/Education Images/Universal Images Group via Getty Images

And so it goes: Burning Man 2021 is canceled. It's the second year in a row, the popular arts festival won't be held in Nevada's Black Rock Desert due to the pandemic.

"We have decided to set our sights on Black Rock City 2022," event officials announced in a blog post on Tuesday. In a frequently-asked-questions section, organizers added: "We've heard from many who don't feel ready to come to Black Rock City. While we're confident in our ability to get a permit and to safeguard public health, we know that co-creating Black Rock City in 2021 would put tremendous strain on our community while we are still ironing out uncertainty."

Many would-be attendees praised the decision in comments on the Burning Man website and on social media as a safe one; others are anxiously anticipating a bigger and better 2022 Burn.

But the cancellation has put many people in the event's host community at ease.

Wary of a trend of rising coronavirus cases in some parts of the region, Washoe County's district health officer Kevin Dick said "the right call was made," in order to lower the risk of spreading infection.

"The event draws thousands of people from all over the world," Dick said in an email. "We are seeing large outbreaks of COVID-19 occurring in a number of countries, areas where very contagious COVID-19 variants of concern are prevalent and where low rates of vaccination are occurring."

The head of a local Paiute tribe is also feeling less burdened knowing there won't be the annual pilgrimage. The main highway to get to the Black Rock Desert playa, which normally draws tens of thousands of people to the summer event, cuts through tribal lands.

"For us it is a sigh of relief," said Janet Davis, chairwoman of the Pyramid Lake Paiute Tribe.

Although the event — which brings in about $63 million to the state annually — gives the tribal community a welcome financial boost, Davis said.

"We don't know who's vaccinated and who's not," she said. "We've been trying to keep our reservation safe and that happening was too soon for us to open."

As with last year, the organization will offer virtual programming during Burn Week, from Aug. 29 through Sept. 7, an experience they say drew 165,000 participants in 2020.

In response to a request for more details on the reasons for the cancellation, Burning Man organizers declined to comment further. Earlier this month, though, CEO Marian Goodell said the organization was "weighing the gravity" of implementing a vaccination requirement that she said challenged "radical inclusion," one of the group's 10 principles.

Still, for many burners, the news won't extinguish their plans to trek to the desert in droves. Just like last year, revelers are preparing to hold unofficial gatherings on public land in place of the annual event.

Last summer, those events — the so-called "rogue" and "free" burns or, unmistakably, "Not Burning Man" — drew an estimated 3,000 people to Black Rock Desert during the time Burning Man is normally held, according to the Bureau of Land Management, the federal agency that approves the organization's permits each year.

Kevin Jervis, one such attendee who now lives in Gerlach — a tiny desert town near the event site — welcomed this year's cancellation.

He called it "more of a relief than anything. ... A lot of us liked it better the way it happened last year."

During the informal festivities, Jervis spent a few days between the playa and its outskirts. He said he and his fellow burners felt like it represented the festival's freewheeling roots.

"I've had friends that have been going since '94 and they said it was a lot more like it used to be. We didn't have to go by regulations," he said. "We could have guns, dogs ... it was a lot freer."

Even before the pandemic, burners increasingly saw an annual gathering under siege.

Event-goers who adhere to Burning Man's counterculture beginnings say the festival's explosion in popularity in the past decade has welcomed a host of bad actors who trash the desert and surrounding communities and disregard the event's founding principles, including "decommodification" and the eco-friendly philosophy of "leave no trace."

Some of those perceived threats come from festival officials themselves, he said. A ticket to the main event alone cost over $400 in 2019 — a financial hurdle critics say goes against another tenet long espoused, that "everyone is invited."

"People that have never been before came out last year because they either couldn't get a ticket other years or they were just kind of curious. Or they didn't have the money to go to the actual Burn," said Jervis.

As for the Pyramid Lake Paiute community, with the reservation largely closed during that period last year, Davis said, "we really didn't see the impact" from a public health standpoint.

"You're not talking about 65 — 75,000 people." While there was more traffic, she said, "they moseyed on through and moseyed on out."

In the years leading up to the pandemic, BLM had been cracking down on the event's growth. Were the festival to return this year, Burning Man organizers said they would have had to meet a population cap of 69,000, down from its 80,000 limit for previous events.

Jervis says he won't miss what he describes as organizers' leniency toward "elites" who set up VIP areas at their camps and hire out to construct their art creations instead of making their own.

"A lot of people have gotten sick of what Burning Man's kind of become," he said.

Even if this year was a go, he said, burners would still be setting up their own Burning Man-adjacent happenings.

Following the announcement of the event's cancellation, people are taking to Facebook groups to reminisce about last year's unsanctioned burns and discuss preparations for their own this summer.

"So it seems that as of today there isn't going to be an official [Burning Man Ceremony] this year," James Zapata wrote. "So who's joining me in the dust?"

This content is from Southern California Public Radio. View the original story at SCPR.org.

Catawba County has upgraded a feed from its 911 Center of the information on calls regarding traffic incidents. The feed shows the type of incident reported, such as a vehicle accident, stranded motorist or vehicle fire, and gives the location of the incident. Only traffic related incidents are reported through this feed.

The committee compiled existing information about the status of children in the county. It also held public meetings and surveyed members of the public about their priorities and ideas. The committee found that most children in the county are well-cared for, but that a substantial number are falling through the cracks. A major cause of concern is the large number of children living in poverty.

Catawba County has launched a performance dashboard, a program that will be the gateway for hundreds of pieces of data on dozens of topics related to the County government, demographics and quality of life. Catawba County Facts and Figures, offers users a choice of exploring data grouped into eight broad categories.

Randy Cress, currently the Systems and Network Manager for Rowan County, North Carolina, is named Catawba County's new Chief Information Officer.

The explosive growth of information technology is having a profound impact on our lives.

Welcome to the public release of the latest Institute of Medicine report on the quality of health care in America.

To significantly reduce the tens of thousands of deaths and injuries caused by medical errors every year, health care organizations must adopt information technology systems that are capable of collecting and sharing essential health information on patients and their care, says a new report by the Institute of Medicine of the National Academies.

Each year, tens of millions of Americans, young and old, choose to learn about science in informal ways -- by visiting museums and aquariums, attending after-school programs, pursuing personal hobbies, and watching TV documentaries, for example.

The best indicator of whether a disabled adult who receives Social Security benefits is capable of managing his or her benefits is evidence of real-world performance of meeting his or her own basic needs, rather than an office-based assessment of financial competence, says a new report from the National Academies of Sciences, Engineering, and Medicine.

We are pleased to announce that the National Academies of Sciences, Engineering, and Medicine are exploring ways to mobilize our expertise to counter misinformation on the web related to science, engineering, and health.

The National Academies of Sciences, Engineering, and Medicines Task Force on the 2020 Census today issued a letter report and submitted it as a public comment to the U.S. Department of Commerce, which recently requested public comments on the 2020 Census.

If the dilute and dispose approach for disposing of the surplus plutonium in the Waste Isolation Pilot Plant (WIPP) is fully implemented, the U.S. Department of Energy (DOE) should use two independent review teams to develop public trust in and improve its decisions, says a new interim report by the National Academies of Sciences, Engineering, and Medicine.

The National Academies today released Criteria for Selecting the Leading Health Indicators for Healthy People 2030, the first of two reports that will help inform the development of Healthy People 2030 (HP2030).

Medicine regulatory authorities — including the U.S. Food and Drug Administration (FDA) — should strengthen cooperation with other countries’ regulators to ensure the quality, safety, and efficacy of medicines, says a new report from the National Academies of Sciences, Engineering, and Medicine.

National Academies host three events to explore ways to expand the reach of accurate science and health information online

In order to enhance the accessibility of trustworthy health information on its platform, YouTube asked the National Academy of Medicine (NAM) to identify preliminary definitions of “authoritative” sources of health information and the criteria by which these sources derive and maintain their authority.

As vaccination campaigns begin ramping up around the world, experts discuss how variants, misinformation, and “brain drain” are affecting pandemic-control efforts.

The U.S. surgeon general has released a public advisory calling misinformation a “serious threat to public health.” The National Academies have been addressing misinformation in health and science on multiple fronts and are taking steps to help cultivate a fact- and evidence-based information environment.

The U.S. Environmental Protection Agency (EPA) should make changes to its integrated risk information system (IRIS) assessments handbook to ensure it provides clear operational instructions for those conducting assessments, and transparency regarding the assessment process, says a new report from the National Academies of Sciences, Engineering, and Medicine.

As the U.N. Climate Change Conference (COP27) approaches, a new report recommends steps to improve the accuracy and usability of greenhouse gas emissions information for decision-makers, including creating a global information clearinghouse.

Nobel Prize laureates and other esteemed experts and leaders will gather at “Truth, Trust and Hope” for a global dialogue on how to stop misinformation from eroding public trust in science. Hosted by NAS and the Nobel Foundation, the summit takes place May 24-26 in Washington, D.C., and virtually.

Registration is now open for the Nobel Prize Summit “Truth, Trust and Hope,” a global conversation on how to stop misinformation from eroding public trust in science. Hosted by NAS and the Nobel Foundation, the summit takes place May 24-26 in Washington, D.C., and virtually.

As health data continues to be a prized target for hackers, here's how to minimize the fallout from a breach impacting your own health records

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Have you ever googled yourself? Were you happy with what came up? If not, consider requesting the removal of your personal information from search results.

Following the takedown of RedLine Stealer by international authorities, ESET researchers are publicly releasing their research into the infostealer’s backend modules

The biggest gaps lie in technology readiness, with only 9 per cent of companies possessing the necessary AI capabilities like machine learning frameworks, prebuilt algorithms, and dynamic compute.

Under the proposed legislation, the owners of platforms like Facebook, Google, Twitter, TikTok and podcasting services would face penalties worth up to five percent of annual global turnover -- some of the highest proposed anywhere in the world.

Every year some of the world’s best young musicians would jet into London to audition for a bursary with the Southbank Sinfonia. Simon Over wanted to cut down on those thousands of air miles and hours in transit. He also didn’t want to miss out on youngsters who couldn’t afford the fare.

With global temperatures rising, an international group of 22 top biologists is calling for a coordinated effort to gather important species information that is urgently needed to improve predictions for the impact of climate change on future biodiversity.

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According to a release, Infosys will work closely with Sector Alarm to migrate their disparate, on-premises Enterprise Resource Planning (ERP) platform onto Microsoft Dynamics 365 Finance and Operations (F&O), helping them modernize their financial and business operating models.

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Ingredient suppliers are making moves to aid today’s beverage-makers. Monin Americas released a Spicy Agave Sweetener, while Kyowa Hakko USA announced the launch of CENTR Enhanced sparkling water.  

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