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Hayden Library - QP355.2.A65 2018

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Nearly half of phase 3 cancer clinical trials carried out by the NCI-sponsored SWOG Cancer Research Network were associated with clinical care guidelines or new drug approvals, a study in JAMA Network Open shows.

An NCI clinical trial finds the drug selumetinib improves outcomes for children with neurofibromatosis type 1 (NF1), shrinking inoperable tumors called plexiform neurofibromas, reducing pain, and improving function and overall quality of life.

Statement from the National Cancer Institute providing information regarding treatment of cancer patients and participation in clinical trials during the COVID-19 pandemic.

News stories on using pets in clinical trials to test veterinarian drugs, debunking the Piltdown Man once and for all, and deciding just how smart crows can be, with David Grimm.   From the magazine It’s really difficult to figure out how old a free-living animal is. Maybe you can find growth rings in bone or other calcified body parts, but in sharks like the Greenland shark, no such hardened parts exist. Using two different radiocarbon dating approaches, Julius Neilsen and colleagues discovered that the giant Greenland shark may live as long as 400 years.   Read the research.   [Image: James Howard McGregor/Wikimedia Commons/Music: Jeffrey Cook]

Though a law requiring clinical trial results reporting has been on the books for decades, many researchers have been slow to comply. Now, 2 years after the law was sharpened with higher penalties for noncompliance, investigative correspondent Charles Piller took a look at the results. He talks with host Sarah Crespi about the investigation and a surprising lack of compliance and enforcement. Also this week, Sarah talks with Brett Finlay, a microbiologist at the University Of British Columbia, Vancouver, about an Insight in this week’s issue that aims to connect the dots between noncommunicable diseases like heart disease, diabetes, and cancer and the microbes that live in our guts. Could these diseases actually spread through our microbiomes? This week’s episode was edited by Podigy. Listen to previous podcasts. About the Science Podcast Download a transcript (PDF). [Image: stu_spivack/Flickr; Music: Jeffrey Cook]

The world is facing a pandemic of COVID-19, for which there is no effective therapy. And any new therapy can be used in medical practice only if its e

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Interview with Rajendra S. Apte, MD PhD, and Gregory P Van Stavern, MD, authors of Association of Preclinical Alzheimer Disease With Optical Coherence Tomographic Angiography Findings

Interview with Anna L. Bruckner, MD, MSCS, author of Assessment of the Timing of Milestone Clinical Events in Patients With Epidermolysis Bullosa From North America

Interview with Joseph M. Unger, PhD, author of Association of Patient Comorbid Conditions With Cancer Clinical Trial Participation

Interview with Christopher R. Cederroth, PhD, author of Association of Genetic vs Environmental Factors in Swedish Adoptees With Clinically Significant Tinnitus

Interview with Christopher W. Goodman, MD, author of A Clinical Overview of Off-label Use of Gabapentinoid Drugs

Interview with Bohdan Pomahac, MD, author of The Evolving Clinical Presentation of Acute Rejection in Facial Transplantation

Interview with Stephen W. Waldo, MD, author of Association of Coronary Anatomical Complexity With Clinical Outcomes After Percutaneous or Surgical Revascularization in the Veterans Affairs Clinical Assessment Reporting and Tracking Program

Interview with Adrian F. Hernandez, MD, MHS, author of Clinical Effectiveness of Direct Oral Anticoagulants vs Warfarin in Older Patients With Atrial Fibrillation and Ischemic Stroke: Findings From the Patient-Centered Research Into Outcomes Stroke Patients Prefer and Effectiveness Research (PROSPER) Study

Interview with Emma B. Holliday, MD, author of Women’s Representation Among Lead Investigators of Clinical Trials in Oncology

Interview with Justin S. Golub, MD, MS, author of Association of Subclinical Hearing Loss With Cognitive Performance

Interview with Nima Sharifi, M.D., author of HSD3B1 Genotype and Clinical Outcomes in Metastatic Castration-Sensitive Prostate Cancer

Interview with James F. Howard, MD, author of Clinical Effects of Self-administered Subcutaneous Zilucoplan in Patients with Moderate to Severe Generalized Myasthenia Gravis: Results of a Phase 2 Randomized, Double-Blind, Placebo-Controlled, Multicenter Clinical Trial

Interview with Jason Ying Kuen Chan, MBBS, author of Practical Aspects of Otolaryngologic Clinical Services During the 2019 Novel Coronavirus Epidemic: An Experience in Hong Kong

Interview with Reisa A. Sperling, MD, author of Association of Factors With Elevated Amyloid Burden in Clinically Normal Older Individuals

The nucleoside inhibitor has advantages over Gilead's remdesivir but has yet to be tested in humans

Drugmakers want to keep trials going but acknowledge that medical resources are strained

Treatment for rare blood cancers could temper cytokine storm in people with severe forms of the disease

Treatment for rare blood cancers could temper cytokine storm in people with severe forms of the disease

Tests of 10 or more novel vaccines could be underway by mid-May

The antimalaria drug will be tested for treating or preventing the disease in thousands of people worldwide

Despite the hype, support for the use of chloroquine and its relative hydroxychloroquine outside a clinical trial remains mixed

Totowa, N.J. : Humana Press, [2007]

Totowa, N.J. : Humana Press, c2007

Milano : Springer Milan, 2006

Totowa, N.J. : Humana Press, [2007]

Milan ; New York : Springer, 2006

Milano : Springer, 2007

New York : Springer, [2007]