assessment Teachers Should Design Student Assessments. But First They Need to Learn How By feedproxy.google.com Published On :: Thu, 18 Jul 2019 00:00:00 +0000 "When the day came to administer the first test I had designed," writes Brandon Lewis, "my heart sank." Full Article Assessment+and+testing
assessment Readiness Assessments Fuel Testing Jitters By feedproxy.google.com Published On :: Fri, 02 Jan 2015 00:00:00 +0000 The collection and use of data about just how prepared individual children are to enter kindergarten can be a ticklish proposition. Full Article Assessment+and+testing
assessment Assessment and Testing By feedproxy.google.com Published On :: Fri, 07 May 2010 00:00:00 +0000 Full Article Assessment+and+testing
assessment NCLB Was Right: Assessment Can Change Instruction By feedproxy.google.com Published On :: Tue, 01 Nov 2016 00:00:00 +0000 What gets tested gets taught, so performance assessments that measure the competencies that matter can lead to instruction that yields those competencies, argues Ben Kornell of Envision Learning Partners. Full Article Nochildleftbehind
assessment Grants for New Assessment Systems Signal the End of the Big Test By feedproxy.google.com Published On :: Mon, 04 Apr 2016 00:00:00 +0000 The Assessment for Learning Project, a partnership between Center for Innovation in Education and Next Generation Learning Challenges, granted twelve grants totaling $2 million for rethinking assessment. Full Article Nochildleftbehind
assessment Turkey disputes US religious freedom commission's assessment of Turkey By feedproxy.google.com Published On :: Fri, 01 May 2020 12:09:00 -0600 CNA Staff, May 1, 2020 / 12:09 pm (CNA).- The Turkish foreign ministry on Wednesday rejected Turkey's inclusion in a report by the US Commission on International Religious Freedom, charging that the report comes from a “biased mindset”. “The report contains baseless, unaccredited and vague allegations as in the past years while trying to portray isolated incidents as violations of religious freedoms through far-fetched accusations,” Hami Aksoy, a spokesperson for the Turkish Ministry of Foreign Affairs, said April 29. “The importance attached by Turkey to protect religious freedoms, including those of religious minorities, is expressed at the highest level by our Government officials. Our authorities make it clear that any harm to the religious freedoms of our citizens will not be tolerated,” Aksoy added. In its 2020 report, USCIRF recommended that the State Department add Turkey, as well as 10 other countries, to a “Special Watch List” of countries where abuses of religious minorities are taking place, but not at a level as severe as in those designated as “countries of particular concern.” The commission wrote that “religious freedom conditions in Turkey remained worrisome” in 2019, “with the perpetuation of restrictive and intrusive governmental policies on religious practice and a marked increase in incidents of vandalism and societal violence against religious minorities.” It cited the Turkish government's prevention of the election of board members for non-Muslim religious groups and its limitations on the election of the Armenian Patriarch of Constantinople. The report added that Alevis, a group related to Shia Islam and the country's largest religious minority, “remained unable to gain official recognition for their gathering houses (cemevleri) as places of worship or to exempt their children from compulsory religious classes, despite European Court of Human Rights (ECtHR) rulings finding that these policies violated Alevis’ rights.” According to the US commission, Turkish religious minorities “expressed concerns that governmental rhetoric and policies contributed to an increasingly hostile environment and implicitly encouraged acts of societal aggression and violence.” The report also drew attention to the permission given for a museum, that was originally a Greek Orthodox church and later a mosque, to be reconverted into a mosque. It noted also that president Recep Tayyip Erdoğan has called for the same thing to happen to the Hagia Sophia, which has the same history. USCIRF also said the Turkish government has “continued to dismiss, detain, and arrest individuals affiliated with, or accused of affiliation with, the U.S.-based cleric Fethullah Gülen, for alleged complicity in a July 2016 coup attempt or involvement in terrorist activity.” Gülen has lived in the US since 1999, and is considered a terrorist by the Turkish government. The Turkish foreign ministry charged that Gülen's mention in the report “amounts to deliberately turning a blind eye” to the coup attempt, and added: “We invite the US authorities to earnestly examine the evidence we have provided” about the Gülen movement “and to engage in effective cooperation in line with the spirit of alliance in order to reveal the true nature of this terrorist organization.” Aksoy added that the recommendation of adding Turkey to a “special watch list” for religious freedom “is a clear indication of the biased mindset behind it and the circles under whose influence it was drawn up.” “In the report that is supposed to include global trends that threaten religious freedoms, the Commission does not mention a single word about xenophobia, Islamophobia and discrimination on religious grounds that is on the rise in the West and the US,” Aksoy stated. “This clearly reveals that the purpose of the report is not to protect religious rights and freedoms. It is clear that the Commission, which has been accused of being anti-Muslim in the past, has drawn up this report based on its unwarranted agenda and priorities under the influence of circles that are hostile to Turkey, rather than objective criteria. We recommend the authors of this report to look in the mirror and engage in self-criticism.” Earlier this year, Turkish authorities arrested a Syriac Orthodox priest on terrorism charges after he provided bread and water to members of a Kurdish separatist group that has been deemed illegal. Full Article Middle East - Africa
assessment Delaware State Housing Authority Releases Delaware Housing Needs Assessment 2015-2020 By news.delaware.gov Published On :: Mon, 08 Sep 2014 17:51:18 +0000 Governor Jack Markell today joined Delaware State Housing Authority (DSHA) for the release of the Delaware Housing Needs Assessment 2015-2020. The report, prepared by GCR Incorporated of New Orleans, Louisiana and The Reinvestment Fund (TRF) of Philadelphia, Pennsylvania, will drive planning for housing resources at DSHA and in communities around the State. With this new analysis of housing needs and market conditions in the state for years 2015-2020, DSHA will be identifying priorities for the next five years and evaluating its programs and strategies. Full Article Delaware State Housing Authority Former Governor Jack Markell (2009-2017) Kent County New Castle County News Office of the Governor Sussex County Housing quality of life ResponsibleGovernment
assessment Performance Flat, But Gaps Widen in International Assessments By feedproxy.google.com Published On :: Tue, 10 Dec 2019 00:00:00 +0000 The United States has gained ground against other countries in a global assessment of teenagers' reading, math, and science skills. That's ironic, though, considering this country has been running in place for years in all three subjects. Full Article International
assessment DPH Invites Public Comment on Delaware Statewide Health Assessment By news.delaware.gov Published On :: Mon, 02 Jul 2018 18:45:02 +0000 The Delaware Division of Public Health (DPH) is seeking input from Delawareans on a draft version of a statewide assessment identifying the primary health needs of First State residents. Full Article Division of Public Health News assessment data DPH feedback health survey
assessment Efsa publishes framework for scientific assessments By chemicalwatch.com Published On :: Thu, 07 May 2020 11:45:00 GMT Intended for staff and external experts Full Article
assessment Risk from pesticide mixtures below threshold in Efsa assessments By chemicalwatch.com Published On :: Thu, 07 May 2020 14:59:00 GMT But campaign group concerned about selected modelling tools Full Article
assessment Free COVID-19 Threat List - Domain Risk Assessments for Coronavirus Threats By www.domaintools.com Published On :: Thu, 23 Apr 2020 08:04:00 -0700 DomainTools is providing a free, curated list of high-risk COVID-19-related domains to support the community during the Coronavirus crisis. The list will be updated daily and available for CSV download. Full Article Company Updates
assessment MHK risk assessment tool set for demonstration in London this month By feedproxy.google.com Published On :: 2015-11-18T16:13:00Z Offshore Renewable Energy (ORE) Catapult and consultancy firm Frazer-Nash, both based in the UK, will perform a live demonstration of their marine hydrokinetics (MHK) energy project risk assessment tool during the International Tidal Energy Summit pre-conference risk and reliability workshop in London on Nov. 23. Full Article
assessment The Pacific Islands Regional Climate Assessment Releases Collaborative Report on Climate Change By feedproxy.google.com Published On :: Wed, 05 Dec 2012 01:30:45 +0000 HONOLULU (December 4, 2012)—The Pacific Islands Regional Climate Assessment (PIRCA) today released its first report, Climate Change and Pacific Islands: Indicators and Impacts (Island Press). The report highlights the findings of more than 100 scientists and other experts who assessed the state of knowledge about climate change and its impacts on the Hawaiian archipelago and the US-Affiliated Pacific Islands. The report also examines the adaptive capacity of island communities in the region. Full Article
assessment Pacific Islands Regional Climate Assessment to Be a Focus of Climate Services Forum in Fiji By feedproxy.google.com Published On :: Thu, 17 Jan 2013 02:51:42 +0000 HONOLULU (Jan.16, 2013) — The Pacific Islands Climate Services Forum to be held next week in Suva, Fiji, will feature discussion of the recently released 2012 Pacific Islands Regional Climate Assessment (PIRCA) report, titled Climate Change and Pacific Islands: Indicators and Impacts. The Forum provides an opportunity for dialogue between climate experts and decision makers, including resource and disaster risk managers and community planners, as well as government ministries and policy makers from across the region. PIRCA editors will present a summary of the report, which incorporates findings of the more than 100 scientists who assessed climate change impacts in Hawai‘i and the US-Affiliated Pacific Islands. Full Article
assessment New Pacific Islands Regional Climate Assessment Website Now Live By feedproxy.google.com Published On :: Tue, 13 Sep 2016 21:12:05 +0000 HONOLULU (September 14, 2016) -- The Pacific Islands Regional Climate Assessment (PIRCA) has launched its new website at PIRCA.org. The website provides a wealth of information and resources about climate change in Hawai‘i and the U.S.-Affiliated Pacific Islands (USAPI). Full Article
assessment In Hawai‘i and the Pacific Islands, Climate Change Means Billions of Dollars of Coastal Damage, Widespread Coral Death and Human Health Risks, Official US Assessment Finds By feedproxy.google.com Published On :: Fri, 23 Nov 2018 20:49:16 +0000 HONOLULU (November 23, 2018) – Strained freshwater supplies, damaged and compromised coastal infrastructure, coral reef death, and greater stresses on native biodiversity and species are among the major concerns and challenges detailed in the Hawai‘i-Pacific Islands chapter of the fourth official US National Climate Assessment, released today. In economic terms, the impacts add up to billions of dollars. The chapter on Hawai‘i and the US-Affiliated Pacific Islands appears in Volume II of the Fourth National Climate Assessment, the most significant US report to assess the effects of climate change on the US economy and communities. The assessment finds that early action to address these impacts can lower economic, environmental, social, and cultural costs and could help to prevent conflict or displacement from lands and resources. Full Article
assessment What happens on an assessment of costs when a costs management order has been made By www.eversheds.com Published On :: 2020-04-02 With a few exceptions, costs budgeting applies to the majority of part 7 multi-track matters. Once the costs budget is agreed between the parties, approved by the court or a costs management order has been made, what is the position upon an assessme... Full Article
assessment Covid-19: Feeling sick? Use digital self-assessment tool HealthCheck By Published On :: Fri, 08 May 2020 12:25:00 GMT Enables early detection, mapping and management of coronavirus using USSD and official government WhatsApp service, Covid Connect Full Article
assessment Visa And Mastercard: COVID-19 And Q1 Results Assessment By seekingalpha.com Published On :: Fri, 08 May 2020 17:01:46 -0400 Full Article AXP PYPL MA V Librarian Capital
assessment Energy Saving Opportunity Scheme: A new mandatory energy assessment scheme for large undertakings By www.eversheds.com Published On :: 2014-08-20 What is the Energy Saving Opportunities Scheme ("ESOS")? ESOS is the UK Government’s implementation of a particular requirement of the Energy Efficiency Directive regarding energy audits. It requires energy assessments (including the ide... Full Article
assessment Japan’s response to COVID-19: A preliminary assessment By www.japantimes.co.jp Published On :: Wed, 06 May 2020 04:20:09 +0900 Will Japan end up in the group of countries that is on the way to successfully containing the virus or in the group that experiences ... Full Article Opinion medicine health covid-19 covid-19 in Japan
assessment Initial AFRICOM Civilian Casualty Assessment Quarterly Report By allafrica.com Published On :: Wed, 06 May 2020 16:11:33 GMT [Africom] As part of the command's commitment to transparency, U.S. Africa Command is implementing a quarterly report on the status of ongoing and completed civilian casualty allegations and assessments. This initiative was directed by U.S. Army Gen. Stephen Townsend, commander, U.S. Africa Command, to increase transparency regarding civilian casualty allegations that are reported to the command while demonstrating the U.S. military's constant commitment to minimizing collateral damage in the pursuit of Full Article
assessment An assessment of coronavirus in the Middle East By www.jpost.com Published On :: Thu, 07 May 2020 20:42:12 GMT Decisions taken by Middle Eastern governments in their fight against the coronavirus reflect differences in administrative capacities, infrastructures and specific national political preferences. Full Article Middle East Coronavirus spread Coronavirus Live Updates
assessment Three ways to enhance student assessments -- by Sungsup Ra, Unika Shrestha By blogs.adb.org Published On :: Mon, 09 Mar 2020 12:35:39 +0800 Developing a holistic national student assessment system can be a colossal undertaking but strategic measures can produce results. Full Article
assessment Knowledge, Attitudes and Practices of Dental Hygienists Regarding Diabetes Risk Assessments and Screenings By jdh.adha.org Published On :: 2020-04-30T12:39:03-07:00 Purpose: Untreated and poorly controlled diabetes causes increased levels of blood glucose associated with poor periodontal disease outcomes. Dental hygienists can play a significant role in screening patients for diabetes mellitus, leading to referral and early diagnosis. The purpose of this study was to determine the knowledge, attitudes, practices, and barriers faced by clinical dental hygienists regarding diabetes risk assessment and screenings.Methods: A mixed method design was used with a convenience sample of dental hygienists in clinical practice (n=316). A 32 item, electronic survey was validated at item-level, and participants were recruited through multiple dental hygiene Facebook groups. Descriptive statistics were used to analyze the data. The survey also included two open-ended attitude questions that were interpreted using thematic analysis to pinpoint common patterns within the data.Results: Dental hygienists had high knowledge scores regarding diabetes and oral health, although many were unaware of their states' specific statutes and regulations for screening practices. Nearly all (95.9%), were likely to educate and refer patients (82%), although fewer than half (40.9%), were likely to perform chairside screening for diabetes. Emergent themes for barriers to screening were time, money, patient acceptance/willingness, lack of education, not having the proper tools, and states' rules and regulations.Conclusion: Despite high knowledge scores regarding diabetes and oral health, there is a gap in regards to dental hygienists' willingness to perform diabetes screenings in a clinical setting. Dental hygienists should be capable of integrating chairside diabetes screening practices into the process of care with proper training. Full Article
assessment Oral Health-Related Quality of Life of Children: An Assessment of the Relationship between Child and Caregiver Reporting By jdh.adha.org Published On :: 2020-04-30T12:39:03-07:00 Purpose: Oral and craniofacial conditions or diseases can impact an individual's health and quality of life. The purpose of this study was to assess the perceived oral health related quality of life (OHRQoL) of children, and evaluate the reported level of agreement between caregivers and their children.Methods: Purposive sampling was used to recruit children ages 8-15, and their caregivers from a dental clinic in a pediatric hospital for this descriptive, cross-sectional study. A modified version of a validated measure, Child Oral Health Impact Profile-Short Form (COHIP-SF), was used for a 22-item questionnaire encompassing three subscales: oral health, functional well-being, and social emotional well-being. Two additional items were included to assess child/caregiver's level of agreement. A dental chart review was also conducted to assess the child's overbite, overjet, and decayed surfaces. Data were analyzed through descriptive statistics and examined for assumptions of normality and linearity.Results: Sixty child/caregiver pairs (n=120) participated in this study. Overbite, overjet and decayed surfaces were not found to be related to any OHRQoL variable, including child/caregiver ratings and overall agreement (p>.05). Average OHRQoL scores for caregivers found to be more positive those of their children (p=.02). Agreement between caregivers and the child's gender was shown to be significant (p=.01). Female child scores differed significantly from males with respect to their caregiver responses (p=.02). Caregivers rated a higher OHRQoL for female children, thus overestimating their female child's reported OHRQoL.Conclusions: The moderate level of agreement found between children and caregivers reinforces the importance of including the child, as well as the caregiver, when assessing OHRQoL. Full Article
assessment Family Medicine Certification Longitudinal Assessment after One Year By www.jabfm.org Published On :: 2020-03-16T09:31:37-07:00 Full Article
assessment Complexities in Integrating Social Risk Assessment into Health Care Delivery By www.jabfm.org Published On :: 2020-03-16T09:31:37-07:00 Full Article
assessment In Vivo Assessment of Size-Selective Glomerular Sieving in Transplanted Human Induced Pluripotent Stem Cell-Derived Kidney Organoids By jasn.asnjournals.org Published On :: 2020-04-30T10:00:29-07:00 Background The utility of kidney organoids in regenerative medicine will rely on the functionality of the glomerular and tubular structures in these tissues. Recent studies have demonstrated the vascularization and subsequent maturation of human pluripotent stem cell–derived kidney organoids after renal subcapsular transplantation. This raises the question of whether the glomeruli also become functional upon transplantation. Methods We transplanted kidney organoids under the renal capsule of the left kidney in immunodeficient mice followed by the implantation of a titanium imaging window on top of the kidney organoid. To assess glomerular function in the transplanted human pluripotent stem cell–derived kidney tissue 1, 2, and 3 weeks after transplantation, we applied high-resolution intravital multiphoton imaging through the imaging window during intravenous infusion of fluorescently labeled low and high molecular mass dextran molecules or albumin. Results After vascularization, glomerular structures in the organoid displayed dextran and albumin size selectivity across their glomerular filtration barrier. We also observed evidence of proximal tubular dextran reuptake. Conclusions Our results demonstrate that human pluripotent stem cell–derived glomeruli can develop an appropriate barrier function and discriminate between molecules of varying size. These characteristics together with tubular presence of low molecular mass dextran provide clear evidence of functional filtration. This approach to visualizing glomerular filtration function will be instrumental for translation of organoid technology for clinical applications as well as for disease modeling. Full Article
assessment An Interrater Reliability Study of Pulmonary Function Assessment With a Portable Spirometer By rc.rcjournal.com Published On :: 2020-04-28T00:42:49-07:00 BACKGROUND:In this study, we aimed to validate the agreement between pulmonary function measurements obtained with a portable spirometer and measurements obtained with conventional spirometry in Chinese pediatric and adult populations.METHODS:Pulmonary function testing was performed to evaluate subjects enrolled at Shanghai Zhongshan Hospital (n = 104) and Shanghai Children's Medical Center (n = 103). The portable spirometers and conventional devices were applied to each subject with a 20-min quiescent period between each measurement. Pulmonary function parameters of FVC, FEV1, peak expiratory flow, maximum expiratory flow at 25%, 50%, and 75% of FVC (MEF25, MEF50, and MEF75, respectively), and FEV1/FVC% were compared with intraclass correlation and Bland-Altman methods.RESULTS:A satisfactory concordance of pulmonary function was observed between spirometry measurements obtained with portable versus conventional spirometers. Intraclass correlation indicated excellent reliability (>0.75) for all pulmonary function indicators in pediatric and adult subjects. Significant positive correlations of all variables measured with different spirometers were observed (all P < .001). No significant bias was observed in either group, although limits of agreement varied. Funnel effects were observed for peak expiratory flow in pediatric subjects and for FVC, FEV1, MEF50, and MEF25 in adult subjects.CONCLUSIONS:The portable spirometer is an alternative to the conventional device for the measurement of pulmonary function. Compared with the conventional device, the portable spirometer is expected to provide convenient, operational, and financial advantages. Full Article
assessment Recent Approaches To Optimize Laboratory Assessment of Antinuclear Antibodies [Minireviews] By cvi.asm.org Published On :: 2017-12-05T08:00:30-08:00 The presence of antinuclear antibodies (ANAs) is a hallmark of a number of systemic autoimmune rheumatic diseases, and testing is usually performed as part of the initial diagnostic workup when suspicion of an underlying autoimmune disorder is high. The indirect immunofluorescence antibody (IFA) technique is the preferred method for detecting ANAs, as it demonstrates binding to specific intracellular structures within the cells, resulting in a number of staining patterns that are usually categorized based on the cellular components recognized and the degree of binding, as reflected by the fluorescence intensity or titer. As a screening tool, the ANA patterns can guide confirmatory testing useful in elucidating a specific clinical diagnosis or prognosis. However, routine use of ANA IFA testing as a global screening test is hampered by its labor-intensiveness, subjectivity, and limited diagnostic specificity, among other factors. This review focuses on current efforts to standardize the nomenclature of ANA patterns and on alternative methods for ANA determination, as well as on recent advances in image-based computer algorithms to automate IFA testing in clinical laboratories. Full Article
assessment Geospatial assessment methods for geotechnical asset management of legacy railway embankments By qjegh.lyellcollection.org Published On :: 2020-05-01T00:46:18-07:00 Most British railway embankments were constructed between 120 and 180 years ago without the benefit of modern design and construction methods. This can result in undesirable load-deformation characteristics and consequent disruption to present-day railway operations, for which there is unprecedented demand. Annual rail passenger kilometres have approximately doubled in the last 20 years and freight has increased by 60% over the same period. Whereas elements such as rails or bridges can be refurbished or replaced to meet increasing demand, the same is not usually feasible for embankments. Development of techniques to assess embankment performance risks posed by operational capacity enhancements is therefore of increasing significance to railway geotechnical asset management. The two case studies presented in this paper demonstrate how geospatial analysis and data management techniques may be applied to this challenge at both strategic (regional or national) and tactical (site-specific) scales for embankments incorporating plastic clay fill. The case studies also demonstrate, in a world of ever more abundant data, the growing need for engineering geologists and geotechnical engineers to augment their traditional knowledge with comprehensive data management and geospatial analysis skills, these being essential for modern infrastructure asset management. Thematic collection: This article is part of the ‘Ground-related risk to transportation infrastructure’ collection available at: https://www.lyellcollection.org/cc/Ground-related-risk-to-transportation-infrastructure Full Article
assessment Proposal for Systemic-Therapy Response-Assessment Criteria at the Time of PSMA PET/CT Imaging: The PSMA PET Progression Criteria By jnm.snmjournals.org Published On :: 2020-05-01T06:31:37-07:00 In around 20% of men with prostate cancer, metastasis develops during the course of their disease. Accordingly, discovering and developing new potent treatment strategies for patients with metastatic prostate cancer has been a major research focus during the last few decades. Identifying disease progression, especially within clinical trials, is essential in determining drug effectiveness. One major remaining question is how best to define disease progression. The criteria of the Prostate Cancer Clinical Trials Working Group (PCWG2) include clinical and laboratory parameters, as well as conventional imaging modalities such as MRI, CT, and bone scan findings, but advanced molecular imaging techniques, especially prostate-specific membrane antigen (PSMA) PET findings, are not considered. This is a problem because PSMA PET is used not only for detecting biochemical recurrence but also for restaging and as an intermediate-endpoint biomarker in ongoing clinical trials. Therefore, response criteria and PSMA PET progression (PPP) criteria need to be established with some urgency. The intent of this article is therefore to define prostate cancer progression by PSMA PET criteria. Our PPP proposal is based on the same principles as were applied for the PCGW2 criteria but adds value by including PSMA PET criteria. PPP defines PSMA treatment response using 3 different criteria. The first is the appearance of 2 or more new PSMA-positive distant lesions. The second is the appearance of 1 new PSMA-positive lesion plus consistent clinical or laboratory data and recommended confirmation by biopsy or correlative imaging within 3 mo of PSMA PET. The third is an increase in size or PSMA uptake of 1 or more existing lesions by at least 30%, plus consistent clinical or laboratory data or confirmation by biopsy or correlative imaging within 3 mo of PSMA PET. Full Article
assessment Development and Implementation of the Readiness Assessment of Emerging Adults With Type 1 Diabetes Diagnosed in Youth (READDY) Tool By spectrum.diabetesjournals.org Published On :: 2020-02-14T06:59:49-08:00 Full Article
assessment Risk Assessment Approach to Microbiological Controls of Cell Therapies By journal.pda.org Published On :: 2020-04-09T09:40:03-07:00 This technology review, written by a small group of pharmaceutical microbiologists experienced in cell therapies, discussed a risk-based approach to microbiological contamination detection and control during gene and cell therapy production. Topics discussed include a brief overview of cell therapies, a risk analysis related to donor selection, cell collection and infectious agent testing, cell transformation and expansion, packaging, storage, and administration, and cell therapy microbial contamination testing and release. Full Article
assessment Diagnostic Utility and Impact on Clinical Decision Making of Focused Assessment With Sonography for HIV-Associated Tuberculosis in Malawi: A Prospective Cohort Study By ghspjournal.org Published On :: 2020-03-31T15:28:55-07:00 ABSTRACTBackground:The focused assessment with sonography for HIV-associated tuberculosis (TB) (FASH) ultrasound protocol has been increasingly used to help clinicians diagnose TB. We sought to quantify the diagnostic utility of FASH for TB among individuals with HIV in Malawi.Methods:Between March 2016 and August 2017, 210 adults with HIV who had 2 or more signs and symptoms that were concerning for TB (fever, cough, night sweats, weight loss) were enrolled from a public HIV clinic in Lilongwe, Malawi. The treating clinicians conducted a history, physical exam, FASH protocol, and additional TB evaluation (laboratory diagnostics and chest radiography) on all participants. The clinician made a final treatment decision based on all available information. At the 6-month follow-up visit, we categorized participants based on clinical outcomes and diagnostic tests as having probable/confirmed TB or unlikely TB; association of FASH with probable/confirmed TB was calculated using Fisher's exact tests. The impact of FASH on empiric TB treatment was determined by asking the clinicians prospectively about whether they would start treatment at 2 time points in the baseline visit: (1) after the initial history and physical exam; and (2) after history, physical exam, and FASH protocol.Results:A total of 181 participants underwent final analysis, of whom 56 were categorized as probable/confirmed TB and 125 were categorized as unlikely TB. The FASH protocol was positive in 71% (40/56) of participants with probable/confirmed TB compared to 24% (30/125) of participants with unlikely TB (odds ratio=7.9, 95% confidence interval=3.9,16.1; P<.001). Among those classified as confirmed/probable TB, FASH increased the likelihood of empiric TB treatment before obtaining any other diagnostic studies from 9% (5/56) to 46% (26/56) at the point-of-care. For those classified as unlikely TB, FASH increased the likelihood of empiric treatment from 2% to 4%.Conclusion:In the setting of HIV coinfection in Malawi, FASH can be a helpful tool that augments the clinician's ability to make a timely diagnosis of TB. Full Article
assessment A Qualitative Assessment of Provider and Client Experiences With 3- and 6-Month Dispensing Intervals of Antiretroviral Therapy in Malawi By ghspjournal.org Published On :: 2020-03-31T15:28:55-07:00 ABSTRACTIntroduction:Multimonth dispensing (MMD) of antiretroviral therapy (ART) is a differentiated model of care that can help overcome health system challenges and reduce the burden of HIV care on clients. Although 3-month dispensing has been the standard of care, interest has increased in extending refill intervals to 6 months. We explored client and provider experiences with MMD in Malawi as part of a cluster randomized trial evaluating 3- versus 6-month ART dispensing.Methods:Semi-structured in-depth interviews were conducted with 17 ART providers and 62 stable, adult clients with HIV on ART. Clients and providers were evenly divided by arm and were eligible for an interview if they had been participating in the study for 1 year (clients) or 6 months (providers). Questions focused on perceived challenges and benefits of the 3- or 6-month amount of ART dispensing. Interviews were transcribed, and data were coded and analyzed using constant comparison.Results:Both clients and providers reported that the larger medication supply had benefits. Clients reported decreased costs due to less frequent travel to the clinic and increased time for income-generating activities. Clients in the 6-month dispensing arm reported a greater sense of personal freedom and normalcy. Providers felt that the 6-month dispensing interval reduced their workload. They also expressed concerned about clients' challenges with ART storage at home, but clients reported no storage problems. Although providers mentioned the potential risk of clients sharing the larger medication supply with family or friends, clients emphasized the value of ART and reported only rare, short-term sharing, mostly with their spouses. Providers mentioned clients' lack of motivation to seek care for illnesses that might occur between refill appointments.Conclusions:The 6-month ART dispensing arm was particularly beneficial to clients for decreased costs, increased time for income generation, and a greater sense of normalcy. Providers' concerns about storage, sharing, and return visits to the facility did not emerge in client interviews. Further data are needed on the feasibility of implementing a large-scale program with 6-month dispensing. Full Article
assessment Structured assessment of frailty in multiple myeloma as a paradigm of individualized treatment algorithms in cancer patients at advanced age By www.haematologica.org Published On :: 2020-05-01T00:05:41-07:00 Full Article
assessment Functional assessment of glucocerebrosidase modulator efficacy in primary patient-derived macrophages is essential for drug development and patient stratification By www.haematologica.org Published On :: 2020-05-01T00:05:42-07:00 Full Article
assessment Assessment of Apparent Internal Carotid Tandem Occlusion on High-Resolution Vessel Wall Imaging: Comparison with Digital Subtraction Angiography [EXTRACRANIAL VASCULAR] By www.ajnr.org Published On :: 2020-04-09T06:30:48-07:00 BACKGROUND AND PURPOSE: Not all tandem occlusions diagnosed on traditional vascular imaging modalities, such as MRA, represent actual complete ICA occlusion. This study aimed to explore the utility of high-resolution vessel wall imaging in identifying true ICA tandem occlusions and screening patients for their suitability for endovascular recanalization. MATERIALS AND METHODS: Patients with no signal in the ICA on MRA were retrospectively reviewed. Two neuroradiologists independently reviewed their high-resolution vessel wall images to assess whether there were true tandem occlusions and categorized all cases into intracranial ICA occlusion, extracranial ICA occlusion, tandem occlusion, or near-occlusion. DSA classified patient images into the same 4 categories, which were used as the comparison with high-resolution vessel wall imaging. The suitability for recanalization of occluded vessels was evaluated on high-resolution vessel wall imaging compared with DSA. RESULTS: Forty-five patients with no ICA signal on MRA who had available high-resolution vessel wall imaging and DSA images were included. Among the 34 patients (34/45, 75.6%) with tandem occlusions on DSA, 18 cases also showed tandem occlusions on high-resolution vessel wall imaging. The remaining 16 patients, intracranial ICA, extracranial ICA occlusions and near-occlusions were found in 2, 6, and 8 patients, respectively, on the basis of high-resolution vessel wall imaging. A total of 20 cases (20/45, 44.4%) were considered suitable for recanalization on the basis of both DSA and high-resolution vessel wall imaging. Among the 25 patients deemed unsuitable for recanalization by DSA, 11 were deemed suitable for recanalization by high-resolution vessel wall imaging. CONCLUSIONS: High-resolution vessel wall imaging could allow identification of true ICA tandem occlusion in patients with an absence of signal on MRA. Findings on high-resolution vessel wall imaging can be used to screen more suitable candidates for recanalization therapy. Full Article
assessment ERT launches patient-administered ECG assessment By www.outsourcing-pharma.com Published On :: Mon, 04 May 2020 15:48:00 +0100 The technology enables sponsors to continue gathering cardiac data for clinical trials without interruption or risk to patient safety. Full Article Clinical Development
assessment National Drug Intelligence Center Releases National Drug Threat Assessment 2010 By www.justice.gov Published On :: Thu, 25 Mar 2010 12:08:03 EDT The National Drug Intelligence Center (NDIC), a component of the Department of Justice and the nation’s principal center for strategic drug intelligence, has released the National Drug Threat Assessment 2010 (NDTA 2010), detailing drug trafficking and abuse trends within the United States. Full Article OPA Press Releases
assessment Justice Department Asks Court to Dismiss Matter Involving the Arkansas Juvenile Assessment and Treatment Center Because Center Has Complied with Agreement By www.justice.gov Published On :: Tue, 20 Nov 2012 18:36:59 EST The Justice Department announced that it has filed a joint motion with the state of Arkansas to dismiss the settlement in United States v. Arkansas, a case involving conditions at the Arkansas Juvenile Assessment and Treatment Center in Alexander, Ark. The state has fully complied with the settlement, which includes reforms in mental health care, fire safety, education and religious freedom for the youth residing at the facility. In addition to complying with the settlement, during the course of the department’s investigation and settlement, the state shifted its focus on juvenile justice from an institution-based model to a community-based model. The result has been a significant statewide decrease in the number of incarcerated youth. At the same time, crime in Arkansas has dropped even though the population of youth under 18 has grown. Full Article OPA Press Releases
assessment Early assessment of <i>KRAS</i> mutation in cfDNA correlates with risk of progression and death in advanced non-small-cell lung cancer By feeds.nature.com Published On :: 2020-05-07 Full Article
assessment Rodent models of post-traumatic stress disorder: behavioral assessment By feeds.nature.com Published On :: 2020-05-06 Full Article
assessment The Need for Creative and Effective Nuclear Security Vulnerability Assessment and Testing By feedproxy.google.com Published On :: Feb 10, 2020 Feb 10, 2020Realistic, creative vulnerability assessment and testing are critical to finding and fixing nuclear security weaknesses and avoiding over-confidence. Both vulnerability assessment and realistic testing are needed to ensure that nuclear security systems are providing the level of protection required. Systems must be challenged by experts thinking like adversaries, trying to find ways to overcome them. Effective vulnerability assessment and realistic testing are more difficult in the case of insider threats, and special attention is needed. Organizations need to find ways to give people the mission and the incentives to find nuclear security weaknesses and suggest ways they might be fixed. With the right approaches and incentives in place, effective vulnerability assessment and testing can be a key part of achieving and sustaining high levels of nuclear security. Full Article
assessment Urban Waste to Energy Recovery Assessment Simulations for Developing Countries By feedproxy.google.com Published On :: Mar 26, 2020 Mar 26, 2020In this paper, a quantitative Waste to Energy Recovery Assessment (WERA) framework is used to stochastically analyze the feasibility of waste-to-energy systems in selected cities in Asia. Full Article
assessment Urban Waste to Energy Recovery Assessment Simulations for Developing Countries By feedproxy.google.com Published On :: Mar 26, 2020 Mar 26, 2020In this paper, a quantitative Waste to Energy Recovery Assessment (WERA) framework is used to stochastically analyze the feasibility of waste-to-energy systems in selected cities in Asia. Full Article
assessment Urban Waste to Energy Recovery Assessment Simulations for Developing Countries By feedproxy.google.com Published On :: Mar 26, 2020 Mar 26, 2020In this paper, a quantitative Waste to Energy Recovery Assessment (WERA) framework is used to stochastically analyze the feasibility of waste-to-energy systems in selected cities in Asia. Full Article