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Capt. Chowta seeks coffee board’s support for arecanut growers of Dakshina Kannada to grow coffee




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Collective action can promote culture of honesty, Maharashtra Upa Lokayukta




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Online education: How Gen Z and millennials can leverage it for career growth

Transformative online education in India for Gen Z and millennials, driving growth and innovation, faces challenges of inclusivity and credibility.




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Indian Sign Language: So the deaf can hear music

Experience of profound deaf individual at live concert with Indian Sign Language interpreters, highlighting ISL expansion and community empowerment




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Every institution can be improved, but that doesn't mean it is fundamentally flawed: CJI Chandrachud in Mumbai

The Chief Justice of India emphasises institutional improvement without undermining the judiciary’s fundamental strength and maturity in decision-making processes




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How simulation using AR, VR can facilitate learning

Simulations in education, from earth-sun-moon system to antimicrobial resistance, enhance learning through interactive virtual experiences.




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Canada ends fast-track visa programme for international students, Indians to be affected

From now on, students need to apply through the regular study permit stream, which accepts Guaranteed Investment Certificates as proof of financial support




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Will the end of SDS Visa derail Indian students’ Canadian dreams?

Canadian government discontinues SDS visa, impacting Indian students with longer processing times, higher fees, and complex procedures.




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India can have global food brands: Yuvraj Singh

Starts his next venture Twiddles, a guilt-free indulgence healthy food brand targeted at the youth and athletes




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Brookfield-led consortium completes acquisition of American Tower’s operations in India

The acquisition, valued at $2.2 billion, encompasses approximately 76,000 communications sites, solidifying the consortium’s commitment to advancing India’s connectivity




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From caves to canvas

The paintings of tribal art mirror life in the villages and the bond between man and nature. While Warli, Pithora and Gond art has found a platform and wide appreciation in various exhibitions over the years, the Saora paintings are a highlight here.




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18F-labelling of nitrogen-containing aryl boronates – anti-cancer drug melflufen as a case study

Org. Chem. Front., 2024, 11,6411-6417
DOI: 10.1039/D4QO01594K, Research Article
Open Access
  This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.
Kevin Bajerke, Fredrik Lehmann, Gunnar Antoni, Kálmán J. Szabó
This study addresses the 18F-labelling of nitrogen-containing arenes via copper-mediated radiofluorination (CMRF). In this case study, derivatives/fragments of the anti-cancer drug melflufen were targeted.
The content of this RSS Feed (c) The Royal Society of Chemistry




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At Via Milano in Hyderabad, the pizza can wait, go for the chops




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Cockroach infestation found at CCMB canteen; hygiene violations flagged at Nacharam restaurants




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India cancel intra-squad match to prioritise net practice ahead of Border-Gavaskar Trophy

India cancels intra-squad match with ‘A’ side in Australia tour for more net practice, focusing on Test series preparation




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India’s coaching staff under the scanner ahead of the Border-Gavaskar series

Gambhir & Co. gets captain Rohit’s backing after the home Test series loss against New Zealand; the head coach says the team has to be honest and keep working hard




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Can skipper Rohit find inspiration to ‘pull’ his side out of the numbing depths?

India has been in similar situations in the past and found a way to bounce back in style. Nothing will motivate the skipper more than the prospect of a statement-making performance down under, especially with qualification for the final of the World Test Championship now hanging by a slender thread




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Indian students can even work in UK after studies: UK minister




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‘Anyone can crack civil services exam’

“I prefer the term ‘civil servant’ to the term ‘bureaucrat’ because it clearly spells out that the ‘master’ is the common man.’’




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You can make the cut

Fashion industry is diverse and vast. How can you carve a niche for yourself?




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Who can study the Vedas?

As an icon of equality, Ramanuja embraced the whole of humanity.




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The Teen’s Ultimate Guide to Making Money When You Can’t Get a Job: 199 Ideas for Earning Cash On Your Own Terms

Whether it was in a department store, fast-food chain, or kiosk in the mall, everyone remembers his or her first job — even more so, you probably remember that first paycheck. But with the current job crisis, it has become harder and harder to enjoy the fruits of your labor. As of October 2011, the […]




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Design, synthesis, biological evaluation, and in silico studies of novel N-substituted-2-(3,4,5-trimethoxyphenyl)-1H-benzo[d]imidazole-6-carboxamides as promising anticancer agents

RSC Adv., 2024, 14,35323-35335
DOI: 10.1039/D4RA04492D, Paper
Open Access
Navid Dastyafteh, Manica Negahdaripour, Mohammad Hosein Sayahi, Mina Emami, Younes Ghasemi, Elham Safaei, Homa Azizian, Zahra Pakrouh Jahromi, Mehdi Asadi, Mohammad Reza Mohajeri-Tehrani, Fateme Zare, Minoo Shahidi, Zahra Pooraskari, Sayed Mahmoud Sajjadi-Jazi, Bagher Larijani, Mohammad Mahdavi, Sara Ranjbar
Synthesis and cytotoxicity evaluation of novel benzimidazoles were explained. The most potent derivative was subjected to cell cycle, apoptosis, and in silico investigations. Compound 5o proved to be a promising anticancer agent.
The content of this RSS Feed (c) The Royal Society of Chemistry




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Macroporous chitosan/alginate hydrogels crosslinked with genipin accumulate and retain glioblastoma cancer cells

RSC Adv., 2024, 14,35286-35304
DOI: 10.1039/D4RA06197G, Paper
Open Access
  This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.
Lauriane Parès, Sahar Naasri, Lisa Delattre, Hélène Therriault, Benoît Liberelle, Gregory De Crescenzo, Marc-Antoine Lauzon, Nathalie Faucheux, Benoit Paquette, Nick Virgilio
This work demonstrates how macroporous hydrogels can be prepared with porous polylactide molds, and homogeneous solutions of sodium alginate and chitosan crosslinked with genipin, in order to accumulate glioblastoma cancer cells.
The content of this RSS Feed (c) The Royal Society of Chemistry




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Design, synthesis, and in vitro and in vivo biological evaluation of triazolopyrimidine hybrids as multitarget directed anticancer agents

RSC Adv., 2024, 14,35239-35254
DOI: 10.1039/D4RA06704E, Paper
Open Access
Heba A. Adawy, Samar S. Tawfik, Abdullah A. Elgazar, Khalid B. Selim, Fatma E. Goda
In response to the urgent need for new anti-proliferative agents, four novel series of triazolopyrimidine compounds (7a–e, 9a–d, 11a–f, and 13a–e) were synthesized and evaluated for in vitro and in vivo anticancer efficacy.
The content of this RSS Feed (c) The Royal Society of Chemistry




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Synthesis and antiproliferative activity of 2-oxo-3-phenylquinoxaline derivatives and related compounds against colon cancer

RSC Adv., 2024, 14,35679-35695
DOI: 10.1039/D4RA06822J, Paper
Open Access
  This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.
M. S. Gomaa, Abdulghany H. A. Ahmed, S. M. El Rayes, Ibrahim A. I. Ali, Walid Fathalla, Mansour S. Alturki, Abdulaziz Hassan Al Khzem, Atiah H. Almalki, Mohammed F. Aldawsari, F. H. Pottoo, Firdos A. Khan, Mohd Amir
The impact of compound 7j on colon cancer cells (HCT-116). Fig. (A) shows the control cells Fig. (B) shows the treatment cells. The arrows show chromatin condensation, nuclear augmentation, and formation of apoptotic bodies.
The content of this RSS Feed (c) The Royal Society of Chemistry




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Physicochemical properties and mechanism of action of a new copper(II) pyrazine-based complex with high anticancer activity and selectivity towards cancer cells

RSC Adv., 2024, 14,36295-36307
DOI: 10.1039/D4RA06874B, Paper
Open Access
  This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.
B. Rogalewicz, T. Sierański, M. Szczesio, A. Olczak, K. Gobis, C. Orlewska, I. Korona-Głowniak, A. Korga-Plewko, M. Iwan, M. Michalczuk, J. Kubik, G. Adamczuk, M. Korga, N. Rutkowska, T. Boruta, K. Gas, M. Sawicki, E. Poleszak, W. Maniukiewicz, M. Świątkowski, A. Czylkowska
The presented work underlines the importance of coordination compounds in the development of new anticancer agents that are safer and more efficient.
The content of this RSS Feed (c) The Royal Society of Chemistry




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Bihar Government cancels 350 contracts worth ₹826 crore awarded by Mahagathbandhan regime

BJP-JDU government cites “irregularities in the process of awarding contracts” by the Public Health Engineering Department, initiates probe. RJD says NDA “scared of Tejashwi Yadav’s popularity”




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The Meghalaya Public Service Commission is under the scanner after Assam and Arunachal Pradesh

A students’ body has asked the panel to justify the ‘missing candidates’ who should have been called for the police service interview according to the prescribed number per post




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Race walker Suraj loses Paris ticket as World Athletics cancels results of Nationals

World body marks results of Indian meet as ‘invalid’)




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Sebastian Coe, multi-millionaire Johan Eliasch among seven candidates for IOC presidency

The IOC, with 111 members currently, is in charge of the Olympic Games and the multi-billion dollar industry linked to the world's biggest multi-sports event.




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Can India avoid defeat in Bengaluru Test?

India were in danger of suffering their first home test loss to New Zealand since 1988, despite Sarfaraz Khan's 150 and Rishabh Pant's 99, when the tourists bowled them out for 462 on the fourth day of their rain-interrupted series opener on Saturday.




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T.N. Health Department takes cancer screening to women at their workplace

To give better access to women for screening of cancer, the Health Department is taking their programmes to work sites and also encouraging women to come in for annual check-ups




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Researchers document huge drop in African elephants in a half century

Fresh evidence of this comes in a study that documents alarming population declines at numerous sites across the continent over about a half century.




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How much can US president-elect Donald Trump derail global climate action?

Trump is a climate change denier who has promised to increase fossil fuel production and withdraw the US from the Paris climate deal, among other worrying pledges.




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You can use text-wrap: balance; on icons

The CSS text-wrap property is (rightfully) widely assumed to be used strictly for text elements. But Terrence Eden posted an article on his blog that shows how it can also be used to balance the way other types of elements wrap, including icons.


You can use text-wrap: balance; on icons originally published on CSS-Tricks, which is part of the DigitalOcean family. You should get the newsletter.




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FACTBOX-Who are the candidates running in the US presidential election?

The upcoming elections in the United States on November 5 have the world on the edge of their seats as they heat up, here is a brief overview of who they are




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Hurricane Milton leaves 16 dead and millions without power in Florida

The hurricane, among the most intense in the Atlantic, has incurred a lowered insurance cost estimate of $30 to $60 billion.




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US and India can work together on mental health, says US Surgeon General Vivek Murthy

US Surgeon General Murthy says it is time to prioritise and accelerate the work on mental health, because the consequences have been too high




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Nijjar killing row: Canada seeks diplomatic immunity waiver; India rejects as political agenda

New Delhi described the accusations as baseless and politically motivated, claiming they serve Prime Minister Justin Trudeau’s domestic vote-bank agenda.




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Nijjar killing: Canadian PM Trudeau admits he had no hard proof when he alleged Indian agents' involvement

Trudeau admits intelligence, not evidence, behind claims of Indian involvement in Nijjar’s killing.




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Biden, Harris celebrate Diwali with 600 Indian American guests at the White House

Biden shared a message of hope and democracy, while Harris highlighted the importance of knowledge and peace in her Diwali message from the campaign trail




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India protests Canada’s allegations against Home Minister Shah, warns of diplomatic fallout

MEA spokesperson Randhir Jaiswal accused Canadian officials of using such insinuations as part of a strategic campaign to damage India’s reputation internationally




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Volcanic eruption burns houses in Indonesia, killing at least 9 people

Authorities raised the danger level and widened the danger zone for Mount Lewotobi Laki Laki on Monday, following a series of eruption that last week




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Musk $1 million voter giveaway can proceed after lawsuit

Pennsylvania Judge Angelo Foglietta on Monday rejected a request to halt the contest by the DA, who called it an illegal lottery




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Trump expands lead, Republican Party captures Senate as Harris path narrows

Trump wins both North Carolina and Georgia, while holding a more tentative advantage across Wisconsin, Michigan, Pennsylvania and Arizona




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Can Brazil save the Amazon rainforest? Marina Silva is trying

‘The challenge of being the leader of COP30 next year, in the heart of the Amazon forest, is huge,’ said Marina Silva, Brazil’s environment minister and top climate diplomat, at an event recently




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Many supporters of Khalistan in Canada, but they do not represent Sikh Community: PM Trudeau

His comments came during Diwali celebrations at Ottawa’s Parliament Hill recently amid an ongoing diplomatic row with India over the killing of Khalistan extremist Hardeep Singh Nijjar




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Trudeau warns US tariffs on Canada would ‘hurt American workers’

The Canadian leader appealed in his comments directly to the interests of Donald Trump, whose strategy throughout his election campaign was to win over blue-collar workers




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Messi scores hat trick as Argentina outclasses Bolivia in South American World Cup qualifying

Lionel Messi shines with a hat trick and two assists in its 6-0 home win as Argentina dominates in World Cup qualifying match