All Classroom Q&A posts on race and gender challenges from the past eight years are described and linked to in this compilation post.

Most districts have the technology to support the basic digital textbooks of today, but not the interactive, multimedia-rich ones of the future.

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This bundle normally sells for $1,149.95 but is available right now for just $596.95, and it will arrive before Christmas with Prime.

For companies to survive and even thrive beyond the coronavirus pandemic, they’re going to have think more like the millennial generation, says Dr Anushka Bogdanov.

Burundi escapó de una guerra civil y años de terror. Hoy se supone que vive en democracia, pero eso está por verse. Ante las próximas elecciones de mayo, y con el panorama de violencia política que asuela el país, parece imposible que éstas se celebren pacíficamente y bajo el paraguas de la democracia.

Sensible, inclusive regulation of pastoralism that has mitigated tension in parts of the Sahel should be extended to the Democratic Republic of Congo (DRC) and the Central African Republic (CAR), where conflicts have worsened with the southward expansion of pastoralism.

In Central African Republic, the conflict between armed groups is now compounded by a conflict between armed communities. The roadmap to end the crisis including elections late 2015 presents only a short-term answer and risks exacerbating existing tensions. The transitional authorities and their international partners must address crucial issues by implementing a comprehensive disarmament policy and reaffirming that Muslims belong within the nation.

The human diseases caused by the fungal pathogens Cryptococcus neoformans and C. gattii are associated with high indices of mortality, and toxic and/or cost-prohibitive therapeutic protocols. The need for affordable antifungals to combat cryptococcal disease is unquestionable. Previous studies suggested benzimidazoles as promising anti-cryptococcal agents combining low cost and high antifungal efficacy, but their therapeutic potential has not been demonstrated so far. In this study, we investigated the antifungal potential of fenbendazole, the most effective anti-cryptococcal benzimidazole. Fenbendazole was inhibitory against 17 different isolates of C. neoformans and C. gattii at a low concentration. The mechanism of anti-cryptococcal activity of fenbendazole involved microtubule disorganization, as previously described for human parasites. In combination with fenbendazole, the concentrations of the standard antifungal amphotericin B required to control cryptococcal growth were lower than those required when this antifungal was used alone. Fenbendazole was not toxic to mammalian cells. During macrophage infection, the anti-cryptococcal effects of fenbendazole included inhibition of intracellular proliferation rates and reduced phagocytic escape through vomocytosis. Fenbendazole deeply affected the cryptococcal capsule. In a mice model of cryptococcosis, the efficacy of fenbendazole to control animal mortality was similar to that observed for amphotericin B. These results indicate that fenbendazole is a promising candidate for the future development of an efficient and affordable therapeutic tool to combat cryptococcosis.

A total of 2,283 Salmonella spp. isolates were recovered from 18,334 samples including patients with diarrhea, food of animal origin and pets across 5 provinces of China. The highest prevalence of Salmonella spp. was detected in chicken meats (39.3%, 486/1,237). Fifteen serogroups and 66 serovars were identified, with Typhimurium and Enteritidis being the most dominant. Most (85.5%, 1,952/2,283) isolates exhibited resistant to ≥ 1 antimicrobial and 56.4% were multi-drug resistant (MDR). A total of 222 isolates harbored extended-spectrum β-lactamases (ESBLs), 200 of which were CTX-M-type that were mostly detected from chicken meat and turtle fecal. Overall, eight bla_CTX-M genes were identified, with bla_CTX-M-65, bla_CTX-M-123, bla_CTX-M-14, bla_CTX-M-79, and bla_CTX-M-130 being the most prevalent. Totally, 166 of the 222 ESBL-producing isolates had amino acid substitutions in GyrA (S83Y, S83F, D87G, D87N, and D87Y) and ParC (and S80I), whilst the PMQR-encoding genes oqxA/B, qepA, and qnrB/S were detected in almost all isolates. Of the fifteen sequence types (STs) identified in the 222 ESBLs, ST17, ST11, ST34, and ST26 ranked among the top 5 in the number of isolates. Our study revealed considerable serovars diversity, high prevalence of co-occurrence of MDR determinants, including CTX-M-type ESBLs, QRDRs mutations and PMQR genes. This is the first report of CTX-M-130 Salmonella spp. from patients with diarrhea and QRDRs mutations from turtle fecal samples. Our study emphasizes the importance of actions, both in the health care settings and in the veterinary medicine sector, to control the dissemination of MDR, especially the CTX-M Salmonella spp. isolates.

Methicillin-resistant Staphylococcus aureus (MRSA) has grown to become a major burden on healthcare systems. The cumulation of limited therapeutic options and worsened patient outcomes with persistent MRSA bacteremia has driven research in optimizing its initial management. The guidelines published by the Infectious Disease of America currently recommend combination therapy for refractory MRSA bacteremia, but the utility of combining antibiotics from the start of therapy is under investigation. The alternative strategy of early use of a β-lactam antibiotics in combination with vancomycin upon initial MRSA bacteremia detection has shown promise. While this concept has gained international attention, providers should give this strategy serious consideration prior to implementation. The objective of this review is to examine retrospective and prospective evidence for early combination with vancomycin and β-lactam antibiotics, as well as explore potential consequences of combination therapy.

The FBI seizes the internet domain to WeLeakInfo.com, a site that was cataloging billions of records, such as email addresses and passwords, from more than 10,300 data breaches at various companies and service providers.

Valencia will need to must a remarkable home recovery to turn round their tie against Atalanta after a 4-1 first-leg defeat.

Today you can save $120 on the Lenovo Flex 14 2-in-1 laptop. Also, the 24-inch Dell S2419HGF 1080p monitor dropped is now just $149.99. Finally, the new Nintendo Switch, featuring improved battery life, is now available.

There are three challenges facing investors going forward, HSBC chief market strategist at HSBC Private Bank tells Fin24.

As shootings break out at high school athletic events, districts must grapple with major questions about their role in keeping venues safe.

The shooting death of a 10-year-old spectator at a high school football game exposes a critical vulnerability and crucial responsibility for schools: keeping people safe at events outside school buildings.

Thanks to its compact, fanless design, the Lenovo ThinkCentre M90n Nano IoT is a tiny and silent mini PC with enough power for basic office and media-streaming tasks, as well as vertical-market and digital-signage use.

Lenovo's IdeaCentre 510A is an unassuming budget desktop in every sense. It'll perform basic tasks without hurting your wallet, but some alternatives do it better at this price point.

Forty-nine Penn State Berks students received recognition for the University Scholastic awards on April 2, through personalized emails. The awards presented included the Evan Pugh Scholars Award,

Jeffrey B. Schwimmer
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SEARCH for Diabetes in Youth Study Group
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Katherine H. Burns
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Coleen A. Boyle
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U19 EURO kicks off in Armenia on Sunday and we pick out a player from each team to keep an eye on.

Penn State Harrisburg faculty share their experiences – the challenges, triumphs and innovations – as they are adapting lesson plans and teaching processes during this time of social distancing.

Online learning holds great potential to transform rural education by ensuring that every student has access to great instruction.

Angel Cintron Jr., Connie Parham, Catlin Tucker, Sheri Edwards, Cheryl Costello, William J. Tolley and George Station explore what blended learning is and how it can be made most effective.

What separates transformative teachers, schools, and districts from those stuck in the routines of the past? The country's best blended teachers have uncovered these commonalities.

A recent school tour of three Bay Area schools with some blended learning experts helped provide answers to some of the common questions we hear about how to implement blended learning.

History teacher Bill Tolley offers tips on adapting to learning environments that combine face-to-face instruction with self-directed online experiences.

Districts across the country are starting to see the blended learning light. We're encouraged by the growing number of forward-thinking leaders who are past the point of needing to be convinced about the potential of blended learning; and are now ready to get serious about implementation.

A survey found that while fewer parents think students should spend considerable time in front of screens in schools, teacher support was unchanged.

We introduce the power and resources released by change. We walk our teachers to the edge of a new world for teaching and learning, step off together and lead while we learn beside our teachers.

The first in a three post series on challenges and opportunities with blended learning, starting with getting to actionable data.

Mica Pollack and her colleagues from UCSD share new research about the importance of teachers in blended learning environments that highlights the strengths and limits of online tools.

Innovative professional development initiatives infuse technology with in-person learning to enhance learning experiences for teachers.

We talk a lot about blended learning opportunities in my district, asking ourselves whether we are offering the most beneficial learning opportunities for both staff and students. We're looking to provide quality online learning resources to students when they are outside of our classrooms, as well

The new "question-of-the-week" is:

Computer programs may help predict students' grades in school as well as determine successful pathways for completing assignments, finds a new Stanford University study.

Using online editing sessions does not affect student scores on standardized writing and reading exams, according to a forthcoming study.

Even great innovations can fail. Will blended learning be one of them? These five factors may help us determine if the new educational model has reached a tipping point.

Modern classrooms are slowly taking a new approach to imparting wisdom and knowledge to the upcoming generation. Traditional classroom teaching techniques are giving way to a new system of blended learning.