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Lactobionic acid modified cobalt coordination polymer-coated peroxymonosulfate nanoparticles generate sulfate/hydroxy dual-radicals for targeted cancer therapy

J. Mater. Chem. B, 2024, Advance Article
DOI: 10.1039/D4TB01777C, Paper
Jiahui Li, Jiaxuan Li, Zelong Chen, Yichen Wan, Yi Wang, Zhichao Pei, Yuxin Pei
LCP NPs were prepared by forming a coordination polymer on peroxymonosulfate through the coordination between imidazole-2-carboxaldehyde and Co2+, then modified with lactobionic acid to improve the efficacy of sulfate/hydroxy dual-radical therapy.
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Exchange of free and capsule conjugated cyanine dyes between cells

J. Mater. Chem. B, 2024, Advance Article
DOI: 10.1039/D4TB01874E, Paper
Zhanna V. Kozyreva, Polina A. Demina, Olga I. Gusliakova, Gleb B. Sukhorukov, Olga A. Sindeeva
Cells readily exchange free cyanine dyes when their membranes are in close contact. Photoconvertible capsules based on cyanine dyes are internalized into the cytoplasm with a low degree of exchange, allowing individual cell labeling and tracking.
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H2O2-activated mitochondria-targeting photosensitizer for fluorescence imaging-guided combination photodynamic and radiotherapy

J. Mater. Chem. B, 2024, Accepted Manuscript
DOI: 10.1039/D4TB01653J, Paper
Qiufen Tian, Zifan Zhu, Yun Feng, Shirui Zhao, Hui Lin, Wen Zhang, Zhiai Xu
Radiotherapy is a primary modality in cancer treatment but accompanied by severe side effects to healthy tissues and radiation resistance to some extent. To overcome these limitations, we developed a...
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Functionalities of pH-responsive DNA nanostructures in tumor-targeted strategies

J. Mater. Chem. B, 2024, Advance Article
DOI: 10.1039/D4TB01883D, Review Article
Liyue Wen, Min Wang
Design and application of various pH-responsive DNA nanostructures for tumor-targeted strategies toward extracellular and intracellular environments are comprehensively reviewed. Their potential and challenges are also critically discussed.
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Advancing cancer therapy with a heptamethine carbocyanine dye-conjugated radionuclide drug

J. Mater. Chem. B, 2024, Advance Article
DOI: 10.1039/D4TB01798F, Paper
Mingxing Huang, Weichen Wang, Yingwei Wang, Rang Wang, Lili Pan, Xin Li, Bo Li, Jingsong Zhang, Ruoxiang Wang, Yi Zhang, Rong Tian
Malignant tumors pose substantial treatment challenges due to their heterogeneity, metastatic potential, and therapeutic resistance, underscoring the urgent need for more effective treatment options.
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Bigg Boss 10: Rahul Dev is finally evicted

Do the producers want us to see more of Nitibha and Manveer?Is that why the less popular contestant got to stay on





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Sonakshi: 'Sexual harassment at work is neglected'

'Women are ashamed of the repercussions that will come when they speak about it.''Women also feel they will be blamed for whatever has happened to them.''Unless women support each other and stand by each other, that will not change.' Sonakshi Sinha speaks out.












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Bigg Boss 11: Who will get evicted? PREDICT!

Will the celebs win over the commoners?




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Bigg Boss 11: 'I can't believe I am evicted!'

'Arshi never crossed her boundary.''Initially, Akash was entertaining but slowly, he's become irritating because he changes groups without being loyal to anyone.' Hiten Tejwani discusses the contestants on Bigg Boss 11, and reserves the worst for Hina Khan.








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#Bigg Boss12: Who will get evicted? PREDICT!

Three celebrities and one commoner are up for eviction. Who will get the final shove?







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Bigg Boss 16: Guess Who Is NOMINATED?

Day 3 inside the Bigg Boss house has the contestants at loggerheads even as they take part in the first nomination task.




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Sajid Khan To Be Evicted From Bigg Boss?

There is now a behind-the-scenes discussion to evict Sajid immediately.




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Bigg Boss 16: Look Who's EVICTED!

Manya Singh got eliminated, and it did not come as a surprise.




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Bigg Boss 16: Will Soundarya Get Evicted? PREDICT!

After Gautam Vig, will his rumoured girlfriend Soundarya Sharma exit the Bigg Boss house?




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Bigg Boss 16: Should MC Stan Be Evicted Next? VOTE

Namrata Thakker lists why it's time for MC Stan to go home.




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Bigg Boss 16: Will Sumbul Get Evicted? Tell Us

Will Sumbul Toqueer Khan get eliminated from the game? Namrata Thakker feels her chances of going home are high.




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Should MC Stan Be Evicted? VOTE!

Until last week, MC Stan was hellbent on leaving Bigg Boss.




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Bigg Boss: Who Will Get Evicted This Week? PREDICT!

Christmas may be around the corner but will that stop an elimination from the Bigg Boss 16 house this weekend?




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Bigg Boss 16: Will Vikas Get Eliminated? PREDICT!

Will he be the latest contestant to leave the show?




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'I get so many calls I get irritated'

'Be it politicians, actors or from any other walk of life, I get calls from everyone saying that Bigg Boss is a great platform for their career and they would love to be a part of the show.'




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Bigg Boss: Superstar Evicted In 24 Hrs!

The second season of Bigg Boss OTT premiered over the weekend on JIO Cinema and it was an exciting watch, thanks to host Salman Khan and an interesting line-up of contestants.




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The augmented classroom

Why not allow connectivity to enrich our knowledge even as we attend classroom lectures?




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CBSE: NEET 2017 will be counted as first attempt




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“With ‘Sherni’, I wanted to move away from the hero archetype”

A unique environmental drama, the recently released ‘Sherni’ is earning accolades from leading Indian conservationists for its accurate portrayal of the modern wildlife crisis




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Amartya Sen and the ‘busted subject’

The Nobel laureate found out that welfare economics was a non-subject at Cambridge




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How Novotel floated its cloud kitchens

The Accor group hotel beat lockdown blues with some smart pivots




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The illuminated and a new way of seeing

Anindita Ghose’s debut novel is a visceral account of loss and emerging anew from it




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Radioactive — How Ushaben’s broadcasts transmitted the message of freedom

The spirited 22-year-old woman, who earned the sobriquet Radioben, was an integral part of the underground radio service during the Quit India movement




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Making all at work feel wanted and valued

When every member of the support function in a company is recognised and respected, it becomes a visible indicator of the culture and happiness quotient of an organisation





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Big Reveal: Will Smith-Jada Separated...

Talk show host and actor Jada Pinkett Smith, 52, has revealed she and actor-husband Will Smith, 55, have been separated and have lived 'completely separate lives' since 2016.




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Utilizing solid-state nanopore sensing for high-efficiency and precise targeted localization in antiviral drug development

Analyst, 2024, 149,5313-5319
DOI: 10.1039/D4AN00946K, Paper
Wei Xu, Lichun Zou, Haiyan Wang, Changhui Xu, Qinyang Fan, Jingjie Sha
The efficient identification and validation of drug targets are paramount in drug discovery and development.
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Electrochemical and imaging evaluations of electrochemically activated screen-printed gold electrodes

Analyst, 2024, 149,5401-5410
DOI: 10.1039/D4AN00990H, Paper
Nor Dyana Zakaria, Ibrahim Luqman Salih, Hairul Hisham Hamzah, Turgut Sönmez, Muhamad Huzaifah Omar, Noorhashimah Mohamad Nor, Khairunisak Abdul Razak, Venugopal Balakrishnan
The graphic abstract displays the integration of the SPGE measurement system with an electrochemical cell-based 3D printing to evaluate the electrochemical behaviors and 3D images of both unactivated and activated SPGEs.
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