high

A highly stable RNA aptamer probe for the retinoblastoma protein in live cells

Chem. Sci., 2020, 11,4467-4474
DOI: 10.1039/D0SC01613F, Edge Article
Open Access
Thao T. Le, Andreas Bruckbauer, Bogachan Tahirbegi, Alastair J. Magness, Liming Ying, Andrew D. Ellington, Anthony E. G. Cass
An RNA G-quadruplex aptamer, specific for the human retinoblastoma protein (RB) and highly stable inside cells, is selected and its application to live cell probing of the protein illustrated.
The content of this RSS Feed (c) The Royal Society of Chemistry




high

N2Phos – an easily made, highly effective ligand designed for ppm level Pd-catalyzed Suzuki–Miyaura cross couplings in water

Chem. Sci., 2020, Advance Article
DOI: 10.1039/D0SC00968G, Edge Article
Open Access
  This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.
Nnamdi Akporji, Ruchita R. Thakore, Margery Cortes-Clerget, Joel Andersen, Evan Landstrom, Donald H. Aue, Fabrice Gallou, Bruce H. Lipshutz
A new, biaryl phosphine-containing ligand, N2Phos, forms a 1 : 1 complex with Pd resulting in an active catalyst at the ppm level for Suzuki–Miyaura couplings in water, enabled by an aqueous micellar medium. Notably, aryl chlorides are shown to be amenable substrates.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry




high

Electrochemical Radical Reactions of Alkyl Iodides: A Highly Efficient, Clean, Green Alternative to Tin Reagents

Chem. Sci., 2020, Accepted Manuscript
DOI: 10.1039/D0SC01694B, Edge Article
Open Access
diyuan Li, Tsz-Kan Ma, Reuben J Scott, Jonathan David Wilden
An electrochemical ‘redox-relay’ system has been developed which allows the generation of C-centered radicals. Intermolecular ‘tin-like’ radical reactions can subsequently be conducted under the most benign of conditions. The yields...
The content of this RSS Feed (c) The Royal Society of Chemistry




high

Reflective teaching in higher education / Paul Ashwin and [and 10 others]

Ashwin, Paul, 1970-




high

Researching higher education : international perspectives on theory, policy and practice / edited by Jennifer M. Case and Jeroen Huisman




high

Corporate humanities in higher education : moving beyond the neoliberal academy / Jeffrey R. Di Leo

Di Leo, Jeffrey R., author




high

Leading the academy : distributed leadership in higher education / Sandra Jones

Jones, Sandra, author




high

Higher education research methodology : a step-by-step guide to the research process / Ben Kei Daniel and Tony Harland

Daniel, Ben Kei, 1971- author




high

Higher education and the future of graduate employability : a connectedness learning approach / edited by Ruth Bridgstock, Neil Tippett




high

International student engagement in higher education : transforming practices, pedagogies and participation / Margaret Kettle

Kettle, Margaret, author




high

Tools and techniques for high performance computing: selected workshops, HUST, SE-HER and WIHPC, held in conjunction with SC 2019, Denver, CO, USA, November 17-18, 2019, revised selected papers / Guido Juckeland, Sunita Chandrasekaran (eds.)

Online Resource




high

Rapid lipolytic oscillations in ex vivo adipose tissue explants revealed through microfluidic droplet sampling at high temporal resolution

Lab Chip, 2020, 20,1503-1512
DOI: 10.1039/D0LC00103A, Paper
Juan Hu, Xiangpeng Li, Robert L. Judd, Christopher J. Easley
High temporal resolution sampling and quantitative detection of glycerol secretion dynamics from adipose tissue using our automated, droplet-based microfluidic system.
The content of this RSS Feed (c) The Royal Society of Chemistry




high

Nanoplasmon-enhanced drop-screen for high throughput single-cell nucleocytoplasmic miRNA profiling

Lab Chip, 2020, Advance Article
DOI: 10.1039/C9LC01226E, Paper
Jia Liu, Guoyun Sun, Shih-Chung Wei, Song Guo, Weikang Nicholas Lin, Chia-Hung Chen
Nanoplasmon-enhanced drop screen is developed to measure single-cell multiple miRNAs with high sensitivity of 0.1 nM, addressing cell nucleocytoplasmic profile in a throughput ∼100 cells per minute.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry




high

Microfluidic device for high-throughput affinity-based isolation of extracellular vesicles

Lab Chip, 2020, Advance Article
DOI: 10.1039/C9LC01190K, Paper
Ting-Wen Lo, Ziwen Zhu, Emma Purcell, Daniel Watza, Joyful Wang, Yoon-Tae Kang, Shruti Jolly, Deepak Nagrath, Sunitha Nagrath
Immunoaffinity based EV isolation technologies use antibodies targeting surface markers on EVs to provide higher isolation specificity and purity compared to existing approaches.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry




high

Acoustic separation of living and dead cells using high density medium

Lab Chip, 2020, Advance Article
DOI: 10.1039/D0LC00175A, Paper
Open Access
Karl Olofsson, Björn Hammarström, Martin Wiklund
A novel, simple and robust route for binary separation of viable and dead cells using a density modified medium which takes advantage of the compromised cell membrane of dead cells.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry




high

High-sensitivity microliter blood pressure sensors based on patterned micro-nanostructure arrays

Lab Chip, 2020, 20,1554-1561
DOI: 10.1039/D0LC00063A, Communication
Nianzuo Yu, Yongshun Liu, Bai Ji, Shuli Wang, Yunyun Chen, Tianmeng Sun, Junhu Zhang, Bai Yang
Blood pressure sensors are proposed to measure the value of central venous pressure, and diagnose the severity of hypertension, hypotension and arterial thrombosis.
The content of this RSS Feed (c) The Royal Society of Chemistry




high

A high-throughput system combining microfluidic hydrogel droplets with deep learning for screening the antisolvent-crystallization conditions of active pharmaceutical ingredient

Lab Chip, 2020, Accepted Manuscript
DOI: 10.1039/D0LC00153H, Paper
Zhening Su, Jinxu He, Peipei Zhou, Lu Huang, Jianhua Zhou
Crystallization of active pharmaceutical ingredients (APIs) is a crucial process in the pharmaceutical industry due to its great impact in drug efficacy. However, conventional approaches for screening the optimal crystallization...
The content of this RSS Feed (c) The Royal Society of Chemistry




high

Legal Research Reports: Greece: Higher Education Reforms and University Asylum

The Law Library of Congress is proud to present the report, Greece: Higher Education Reforms and University Asylum.

This report discusses the legislative history of the university asylum rule that prohibits police from entering universities without permission of a three-person panel (with exceptions). Relevant legislation and legislative resources are highlighted. A short bibliography is also included. (Nov. 2019)

This report is one of many prepared by the Law Library of Congress. Visit the Comprehensive Index of Legal Reports page for a complete listing of reports and the Current Legal Topics page for our highlighted and newer reports. 




high

Highest viewership for PM Modi’s TV address to the nation on lockdown-2

Data suggests average daily reach has now stabilised at 627 million. The highlight of the week was an all-time high viewership of 4 billion impressions by the Hindi GEC genre in the Hindi speaking market, urban region.




high

Gujarat: Doctors plan study to reduce high infant mortality rate in tribal areas

SAVING FUTURE: The medical practitioner saYS 50-70 per cent of deaths take place within one month of birth




high

The Experience of Being First in Family at University [electronic resource] : Pioneers in Higher Education / by Sharron King, Ann Luzeckyj, Ben McCann

King, Sharron, author




high

Higher Education, Pedagogy and Social Justice [electronic resource] : Politics and Practice / edited by Kelly Freebody, Susan Goodwin, Helen Proctor




high

Mature-Age Male Students in Higher Education [electronic resource] : Experiences, Motivations and Aspirations / by Madeleine Mattarozzi Laming, Aileen Morris, Pamela Martin-Lynch

Laming, Madeleine Mattarozzi, author




high

Strategies for Resisting Sexism in the Academy [electronic resource]: Higher Education, Gender and Intersectionality




high

[ASAP] Development of Mischmetal–Fe–Co–B Permanent Magnet Alloys via High-Throughput Methods

ACS Combinatorial Science
DOI: 10.1021/acscombsci.9b00190




high

Annual Report to the Nation: Overall cancer mortality continues to decline; Special section on adults ages 20 to 49 shows higher cancer incidence and mortality for women than men

The 2019 Annual Report to the Nation on the Status of Cancer finds overall cancer death rates continue to decline and cancer incidence dropped in men and remained stable in women. A special section reports on recent cancer trends in younger adults.




high

Higher daily step count linked with lower all-cause mortality

In a new study, higher daily step counts were associated with lower mortality risk from all causes. Researchers found that the number of steps taken each day, but not the intensity of the stepping, had a strong association with mortality.




high

[ASAP] Removal of Hydrogen Poisoning by Electrostatically Polar MgO Support for Low-Pressure NH<sub>3</sub> Synthesis at a High Rate over the Ru Catalyst

ACS Catalysis
DOI: 10.1021/acscatal.0c00954




high

[ASAP] Highly Enantioselective Construction of Fully Substituted Stereocenters Enabled by <italic toggle="yes">In Situ</italic> Phosphonium-Containing Organocatalysis

ACS Catalysis
DOI: 10.1021/acscatal.0c01079




high

[ASAP] Gold(I)-Catalyzed Highly Enantioselective [4 + 2]-Annulations of Cyclopentadienes with Nitrosoarenes via Nitroso-Povarov versus Oxidative Nitroso-Povarov Reactions

ACS Catalysis
DOI: 10.1021/acscatal.0c01293




high

[ASAP] Highly Efficient Ultralow Pd Loading Supported on MAX Phases for Chemoselective Hydrogenation

ACS Catalysis
DOI: 10.1021/acscatal.0c00082




high

Coronavirus | U.S. unemployment rate spikes to 14.7%, highest since Great Depression

As companies have laid off tens of millions, lives have been upended across the country.




high

High altitude humans living ~11,000 years ago (24 October 2014)

Kurt Rademaker discusses his work exploring the Andean plateau for artifacts of the earliest high-altitude humans, Paleoindians that lived at 4500 meters more than 11,000 years ago. Hosted by Sarah Crespi. [Img: David-Stanley/Flickr]




high

High-altitude bird migration and a news roundup

Charles Bishop discusses the "roller-coaster" flight strategy of bar-headed geese as they migrate across the Himalayas between their breeding and wintering grounds. Online news editor David Grimm discusses daily news stories. Hosted by Sarah Crespi. [Img: © Nyambayar Batbayar]




high

Podcast: Science lessons for the next U.S. president, human high altitude adjustments, and the elusive Higgs bison

This week, we chat about some of our favorite stories—jumping spiders that can hear without ears, long-lasting changes in the human body at high altitudes, and the long hunt for an extinct bison—with Science’s Online News Intern Jessica Boddy. Plus, Sarah Crespi talks to Deputy News Editor David Malakoff about six science lessons for the next U.S. president.    [Image: Gil Menda at the Hoy Lab; Music: Jeffrey Cook]




high

Podcast: Giant virus genetics, human high-altitude adaptations, and quantifying the impact of government-funded science

This week, viruses as remnants of a fourth domain of life, a scan of many Tibetan genomes reveals seven new genes potentially related to high-altitude life, and doubts about dark energy with Online News Editor David Grimm. Danielle Li joins Sarah Crespi to discuss her study quantifying the impact of government funding on innovation by linking patents to U.S. National Institutes of Health grants. Listen to previous podcasts. Download the show transcript. Transcripts courtesy of Scribie.com. [Image: artubo/iStockphoto; Music: Jeffrey Cook]




high

Effective methods for the determination of triphenyltin residues in surface water and soil samples by high-performance liquid chromatography with tandem mass spectrometry

Anal. Methods, 2020, Advance Article
DOI: 10.1039/D0AY00329H, Paper
Gabriel C. dos Santos, Állisson A. da S. Avellar, Rômulo de O. Schwaickhardt, Nelson M. G. Bandeira, Filipe F. Donato, Osmar D. Prestes, Renato Zanella
Monitoring of triphenyltin (TPhT) in the environment, particularly to control its misuse in agriculture, is of great importance because of its high toxicity.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry




high

Versatile additively manufactured (3D printed) wall-jet flow cell for high performance liquid chromatography-amperometric analysis: application to the detection and quantification of new psychoactive substances (NBOMes)

Anal. Methods, 2020, 12,2152-2165
DOI: 10.1039/D0AY00500B, Paper
Open Access
Hadil M. Elbardisy, Eduardo M. Richter, Robert D. Crapnell, Michael P. Down, Peter G. Gough, Tarek S. Belal, Wael Talaat, Hoda G. Daabees, Craig E. Banks
Additive manufacturing is an emerging technology of vast applicability, receiving significant interest in a plethora of industrial and research domains as it allows the translation of designs produced via computer software, into 3D printed objects.
The content of this RSS Feed (c) The Royal Society of Chemistry




high

High cytotoxic activity of ZnO@leucovorin nanocomposite based materials against an MCF-7 cell model

Anal. Methods, 2020, 12,2176-2184
DOI: 10.1039/D0AY00498G, Paper
Mohamed Fathi Sanad, Esraa Samy Abu Serea, Shereen Magdy Bazid, Shimaa Nabih, Md Ariful Ahsan, Ahmed Esmail Shalan
In the current work, we design a multifunctional hybrid nanocomposite for treating MCF-7 cell lines, which act as a model for breast cancer cells, to overcome the serious side-effects of chemotherapy treatment pathways.
The content of this RSS Feed (c) The Royal Society of Chemistry




high

Multi-residue determination of micropollutants in Nigerian fish from Lagos lagoon using ultrasound assisted extraction, solid phase extraction and ultra-high-performance liquid chromatography tandem mass spectrometry

Anal. Methods, 2020, 12,2114-2122
DOI: 10.1039/D0AY00411A, Paper
Idera Fabunmi, Natalie Sims, Kathryn Proctor, Aderonke Oyeyiola, Temilola Oluseyi, Kehinde Olayinka, Barbara Kasprzyk-Hordern
This reports for the first time a simple and robust approach in determining pharmaceuticals in different fish species in Nigeria.
The content of this RSS Feed (c) The Royal Society of Chemistry




high

A high-throughput plasmonic tongue using an aggregation assay and nonspecific interactions: classification of taste profiles in maple syrup

Anal. Methods, 2020, Advance Article
DOI: 10.1039/C9AY01942A, Paper
Simon Forest, Trevor Théorêt, Julien Coutu, Jean-Francois Masson
A simple colorimetric test detects off-flavour profiles of maple syrups in minutes, which are detectable by the naked eye.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry




high

Miniaturized QuEChERS method for determination of 97 pesticide residues in wine by ultra-high performance liquid chromatography coupled to tandem mass spectrometry

Anal. Methods, 2020, Accepted Manuscript
DOI: 10.1039/D0AY00744G, Paper
Gabrieli Bernardi, Magali Kemmerich, Martha B Adaime, Osmar Damian Prestes, Renato Zanella
A miniaturized sample preparation method was developed and validated for the multiresidue determination of 97 pesticide residues in wine samples. The proposed extraction procedure is based on QuEChERS acetate method...
The content of this RSS Feed (c) The Royal Society of Chemistry




high

NHAI to resume toll collection on national highways from April 20

Replying to a letter from NHAI, the ministry said the NHAI in letters dated April 11 and 14 has highlighted reasons for resuming the collection of user fee on national highways, saying that the Ministry of Home Affairs has allowed a lot of activities with effect from April 20, including commercial and private establishments and construction activities.




high

NHAI to resume toll collection on National highways from April 20

Besides construction activity, the home ministry has allowed commercial and private establishments to resume operations. Toll collection falls under this category. Interstate and intra-state movement of all trucks and other goods or carrier vehicles has also been allowed.




high

Transporters say not able to sustain highway toll charges

The All India Motor Transport Congress (AIMTC), the apex body for transporters that represents about 95 lakh truckers and transport entities, sought suspension of toll till May 3.




high

Toll collection resumes on National Highways

National Highways Authority of India (NHAI) as well as highway developers resumed collection at toll plazas. Highways developer IRB Infrastructure Developers said all its Special Purpose Vehicles (SPVs) "have resumed their toll collection from 00.00 hours today" in line with the NHAI directives.




high

70% Highway projects resume after partial lifting of lockdown

As the ministry of home affairs (MHA) made way for lifting curbs on certain sectors to get economic activity restarted, construction activity is still crawling, though it has started across various districts.




high

Managing state transportation research programs: a synthesis of highway practice / Donald Ludlow, Vivek Sakhrani, Camille Wu

Barker Library - TE7.N2755 no.522




high

Prioritization of freight investment projects: a synthesis of highway practice / Mario M. Monsreal, Matthew Miller, Madison Metsker-Galarza, Madison Graham, Juan Carlos Villa

Barker Library - TE7.N2755 no.542




high

The highway capacity manual: a conceptual and research history. / Elena S. Prassas, Roger P. Roess

Online Resource