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Music really does sound better when you're high, scientists report

Neuroscientists have confirmed what every stoner already knows: music sounds better when you're high on weed. In a paper titled "Exploring the interaction between cannabis, hearing, and music," researchers from Toronto Metropolitan University reported results from a study in which participants "reported significantly greater hearing sensitivity and levels of state absorption while high compared to sober." — Read the rest

The post Music really does sound better when you're high, scientists report appeared first on Boing Boing.





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Mark Milley Fears He Will Face a Court-Martial When Trump Enters White House

Retired Gen. Mark Milley is afraid of retribution. The former chairman of the Joint Chiefs of Staff and a four-star Army general made no bones about his feelings about former […]

The post Mark Milley Fears He Will Face a Court-Martial When Trump Enters White House appeared first on The Western Journal.




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Can I? When Doubt Kills Your Ideas

Alright! The Muses sing, drawing you to the desk, pump your veins with hot blood and fill your mind with combustible imagination. You’re on fire and ready to write. The idea once tumbling in your mind is bucking with life and wants to breath words on your screen. It’s awesome. You’re awesome. All is good.

Then the passions temper under the cool, steady light of your computer screen. The process of fleshing out your idea with words demands time. So much so, you feel the vibrant energy of your story suffocate under the process. Now you’re using the logical, analytical side of your brain. Each scene or circumstance demands continuity and must fit into the internal logic of your world. Everything must make sense; else the reader will dismiss this pile of junk for amateur hubris.

With logic comes the questions. A train of them, each rumbling down the tracks uncaring of the idea which once bucked in the stables of your mind, eager for freedom, now tied to the rails. All of the doubts can easily be summarized into “Can I?”

Of course, this isn’t the real question haunting the halls of your mind.

Continue reading Can I? When Doubt Kills Your Ideas at Mythic Scribes.





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When will we see below-freezing temperatures in Milwaukee? First frost, snow forecasts




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When Taxol met tubulin [Classics]

When the drug Taxol® was approved by the United States Food and Drug Administration in 1993, it was a game changer for cancer patients. The compound, which arrests cell division by preventing the disassembly of tubulin microfibers, has been used over the past three decades to treat millions of cases of breast, lung, and ovarian cancer as well as Kaposi's sarcoma. In 1990, Bristol Myers Squibb applied to trademark the name Taxol, which was approved in 1992, changing the drug's generic name to paclitaxel.At the time that Taxol was entering clinical trials in the late 1970s, it also proved to be a valuable tool for cytoskeletal research. Tubulin had been discovered in the late 1960s, but it was still unclear how the soluble protein dimer polymerized (Fig. 1) to form the long, complex structures of the cytoskeleton.jbc;295/41/13994/F1F1F1Figure 1.Strands of tubulin, a protein in the cell's skeleton, photographed using a high-resolution microscopy technique. Image made by Pakorn Kanchanawong (National University of Singapore) and Clare Waterman (NHLBI, National Institutes of Health).“Back then, people were just discovering the most basic functions of tubulin and how it polymerized, and then they found a drug that affected this,” said Velia Fowler, a cell biologist at the University of Delaware and former Associate Editor at the Journal of Biological Chemistry.The drug and its cytoskeletal activity intersected in the 1981 JBC paper “Taxol-induced polymerization of purified tubulin” (1), the subject of this JBC Classic. In the single-author paper, Nirbhay Kumar, then a postdoctoral fellow at the National...




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Problem Notes for SAS®9 - 66537: SAS Customer Intelligence Studio becomes non-responsive when you delete a calculated variable from the Edit Value dialog box

In SAS Customer Intelligence Studio, you might notice that the user interface becomes unresponsive, as shown below: imgalt="SAS Customer Intelligence Studio UI becomes unresponsive" src="{fusion_66537




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Problem Notes for SAS®9 - 66540: SAS Management Console and SAS Data Integration Studio might return the message "table failed to update" when you use the Update Metadata tool

You encounter this issue when the table metadata matches the data source. In this scenario, no metadata update is required.




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Problem Notes for SAS®9 - 66487: Authentication to the CAS server fails with the error "Access denied..." when initiated on a SAS/CONNECT server in a Microsoft Windows environment

You might see the following error messages: "ERROR: Connection failed. Server returned: SAS Logon Manager authentication failed: Access denied." and "ERROR: Unable to connect to Cloud Analytic Services host-name on port 5570. Veri




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Problem Notes for SAS®9 - 66509: Several procedures in SAS/STAT Software and SAS/QC Software generate incorrect results when an OBSMARGINS= data set is used

If the response variable is in the CLASS statement variable list before the class variables that also appear in the MODEL statement, and an OM-data-set is used, least squares means results for several of the statistical procedures are incorrect.




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Problem Notes for SAS®9 - 66391: Opening a database table returns a Segmentation Violation when you use the Metadata LIBNAME engine (META)

You might receive a Segmentation Violation when opening a database table in SAS. The SAS Log contains the error and traceback:


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Problem Notes for SAS®9 - 33449: An error might occur when you use SAS 9 BULKLOAD= and BULKEXTRACT= options to load data to or extract data from the HP Neoview database on the HP Itanium platform

An error might occur when you use the SAS 9 BULKLOAD= and BULKEXTRACT= options load data to or extract data from HP Neoview on the HP Itanium platform. The problem occurs because Hewlett-Packard changed the name of one of




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Problem Notes for SAS®9 - 48028: Custom Time Frame-based data versions do not aggregate correctly when referenced in worksheets with standard hierarchy levels

In SAS Merchandise Financial Planning, custom time frame-based data versions do not aggregate correctly when referenced in worksheets with standard hierarchy levels. The data does not aggregate correctly from l




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Problem Notes for SAS®9 - 66535: You might intermittently see the error "RangeError: Maximum call stack exceeded..." when viewing a SAS Visual Analytics report

When viewing a SAS Visual Analytics report, you might intermittently see an error that includes content similar to the following:

Error Message:




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Problem Notes for SAS®9 - 66505: The OBS= option does not generate a limit clause when you use SAS/ACCESS Interface to PostgreSQL to access a Yellowbrick database

When you use SAS/ACCESS Interface to PostgreSQL to query a Yellowbrick database, the SAS OBS= option is not generating a limit clause on the query that is passed to the database. Click the



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Problem Notes for SAS®9 - 66496: Titles and footnotes do not span the full width of a page when you use the COLUMNS= option with the TAGSETS.RTF_SAMPLE tagset

Titles and footnotes do not span the entire width of the page when you use the COLUMNS= option with a value that is greater than 1 with the TAGSETS.RTF_SAMPLE tagset. When a value that is greater than 1 is specified for th




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Problem Notes for SAS®9 - 66500: A content release on the SAS Risk Governance Framework fails to load when you use SAS 9.4M7 (TS1M7) on the Microsoft Windows operating system

When you log on to the SAS Risk Governance Framework and choose a solution, the web application might fail to load the solution content. When the problem occurs, you continue to see "Loading..." on the screen, an




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To be there when the picture is being painted [Protein Structure and Folding]

There is nothing quite like the excitement of discovery in science—of finding something no one else knew and seeing a story unfold. One has to be part of an emerging picture to feel the elation. These moments in a lifetime are few and far between, but they fuel enthusiasm and keep one going. They are embedded in struggles and joys of everyday life, years of establishing what Louis Pasteur called “the prepared mind,” working with mentors, trainees, and colleagues, failures and successes. This article recalls 1) how I got to be a biochemist; 2) my contributions as an educator and researcher, especially regarding meprin metalloproteases; and 3) my participation in communities of science. Perhaps my reflections will help an aspiring scientist see how fulfilling a career in science can be.




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Tension Rises in States Over Who Decides When to Reopen Schools

School administrators in some states are caught up in tensions about who gets the final say about when they can reopen their buildings and what precautions they should take to protect their communities.




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Armed Staff Keep Rural Schools Safe When Police Are Far Away, Panel Hears

Arming some school staff provides a needed safety option for rural districts far from law enforcement, educators told the Federal School Safety Commission during an Arkansas site visit Wednesday.




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Tension Rises in States Over Who Decides When to Reopen Schools

School administrators in some states are caught up in tensions about who gets the final say about when they can reopen their buildings and what precautions they should take to protect their communities.




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See What Happened When One Museum Asked Artists to Define ‘Home’

The Smithsonian Design Triennial presents 25 commissions that explore the physical and conceptual ideas of shelter and refuge




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What Happens When Galaxies Collide?

In about four billion years from now, the Milky Way and Andromeda galaxies will crash together Visualization: NASA, ESA, and F. Summers, STScI Simulation credit: NASA, ESA, G. Besla, Columbia University, and R. van der Marel, STScI




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Ask Smithsonian: What Does the World Look Like When You're Color Blind?

Learn more about color blindness: https://www.smithsonianmag.com/smithsonian-institution/ask-smithsonian-how-does-world-look-the-color-blind-180960415/ Have a question in mind? It's your turn to Ask Smithsonian: https://www.smithsonianmag.com/smithsonian-institution/ask-smithsonian/ask-form/




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Ask Smithsonian: When Will the Leaning Tower of Pisa Topple?

Have you ever wondered if the Leaning Tower of Pisa is a catastrophe waiting to happen? In this one-minute video, Ask Smithsonian host Eric Schulze explains how architects and engineers spent the last eight hundred years or so making things go from bad to worse, bringing the gravity-defying tower to the brink of disaster




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Ask Smithsonian: When Did People Start Keeping Pets?

Man’s best friend is also one of his oldest.




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What Happens When the Colorado River Dries Up?

What happens when one of the nation's largest rivers dries up? Photojournalist Pete McBride tells us about the consequences of a prolonged drought in the Colorado River, which provides drinking water and electricity to millions of Americans, and shares his experience walking the river from end to end. What can we learn from the landscape revealed by the historically low water levels, and will they become the new normal? Read “The Breathtaking Glen Canyon Reveals Its Secrets (https://www.smithsonianmag.com/science-nature/glen-canyon-reveals-its-secrets-180980754/) ,” photographs & text by Pete McBride, Smithsonian, October 2022. Learn more about Pete and his work at his site (https://petemcbride.com/) . There’s More to That is a production of Smithsonian magazine and PRX Productions. From the magazine, our team is Chris Klimek, Debra Rosenberg and Brian Wolly. From PRX, our team is Jessica Miller, Adriana Rosas Rivera, Genevieve Sponsler, Terence Bernardo, and Edwin Ochoa. The Executive Producer of PRX Productions is Jocelyn Gonzales. Episode artwork by Emily Lankiewicz. Music by APM Music.




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Ask Smithsonian: Why Does My Nose Run When It’s Cold Outside?

Host Eric Schulze opens the floodgates of knowledge to reveal the answer.




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When Your Great-Great-Great-Grandfather Is a Civil War Hero

Photographer Drew Gardner has a passion for history. His long-term project, “The Descendants,” (https://www.drewgardner.com/descendants)  wherein he recreates famous portraits of historical figures featuring their direct offspring, is his most visible expression of this interest. But like a lot of people who study history, Gardner has in recent years begun to contemplate more deeply the question of whose stories have been judged worthy of preservation, and whose have been allowed to fade into obscurity. That was how he decided to shift his specific focus to locating and photographing Black American descendants of Civil War veterans. You can take a look at Gardner’s photographs and read magazine editor Jennie Rothenberg Gritz’s exploration of their meaning here (https://www.smithsonianmag.com/history/descendants-black-civil-war-heroes-wear-heritage-pride-180983397/) . On the latest episode of the Smithsonian podcast “There’s More to That,” (https://www.smithsonianmag.com/podcast)  I speak with Janisse Flowers and her 9-year-son, Neikoye, who are descended from the Civil War drummer boy David Miles Moore Jr. After some reflection, Janisse and her husband decided to grant Gardner’s request to photograph Neikoye dressed in a replica of Moore’s Union Army uniform. Both Janisse and Neikoye share their surprise over how this experience made them more conscious of their heritage. I’m also joined by Gardner himself, who describes the challenges—and, he hopes, the potential benefits—of asking Black Americans to revisit one of the most painful chapters of America’s history by (almost) literally stepping into their ancestors’ shoes. You can learn more about Drew and his work at his website (https://www.drewgardner.com/) . Find prior episodes of our show here (https://www.smithsonianmag.com/podcast/) . There’s More to That is a production of Smithsonian magazine and PRX Productions. From the magazine, our team is Chris Klimek, Debra Rosenberg and Brian Wolly. From PRX, our team is Jessica Miller, Adriana Rosas Rivera, Genevieve Sponsler, Terence Bernardo, and Edwin Ochoa. The Executive Producer of PRX Productions is Jocelyn Gonzales. Fact-checking by Stephanie Abramson. Episode artwork by Emily Lankiewicz. Music by APM Music.




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Astronomers Are Watching for a Once-in-a-Lifetime Nova Explosion. When Will We See It?

A recurrent nova, known as the Blaze Star or T Coronae Borealis, is predicted to soon appear in the night sky. But the exact timing of the rare eruption remains unknown




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When Art Thieves Stole Four Andy Warhol Prints, They Didn't Realize Only Two Would Fit in the Getaway Car

The robbers only made away with two of the screen prints, which they swiped from a gallery in the Netherlands. They abandoned the other artworks on the street




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Forty-Three Monkeys Are on the Loose in South Carolina After Escaping a Research Facility When a Door Was Left Unsecured

Once the first primate made a break, the 42 others followed suit in a simple case of monkey-see, monkey-do




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When a Search Party Discovered the Frozen Body of a British Explorer Who Raced to the South Pole—and Lost

On this day in 1912, a team found the remains of Robert Falcon Scott and the crew of the "Terra Nova" expedition. A would-be rescuer said he was forever haunted by the "horrible nightmare"




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This Is What You're Paying for When You Buy a Bentley

Manufacturing a Bentley in the traditional way is a time-consuming nod to their brand heritage. Each hand-crafted wheel can take 4.5 hours to finish




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Residents across river from Dawson City, Yukon, stepping up to help neighbours when emergency services limited

A group of volunteers have been providing emergency services to West Dawson residents during the periods of freeze up and break up, when there is no reliable access across the Yukon River to town.



  • News/Canada/North

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When the Nazis Seized Power, This Jewish Actor Took on the Role of His Life

After he was forced off the German stage in 1934 by antisemitic hecklers, Leo Reuss found a daring way to hide in plain sight




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When White Supremacists Staged the Only Successful Coup in U.S. History

The 1898 Wilmington massacre left dozens of Black North Carolinians dead. Conspirators also forced the city's multiracial government to resign at gunpoint




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Santa Claus is coming to town: When and where to catch local parades

Here comes Santa Claus! There are a number of parades set to take place in November and December both during the day and in the evening. Here's a list of where you can find the big man in red.



  • News/Canada/Kitchener-Waterloo

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Who gets Fluffy when you're gone? Pet inheritance is more complex than you might think

The high cost of pet care can be an unfair burden to place on your family when you’re gone. Experts say you should set aside cash pet care expenses, and make sure you have a trusted beneficiary in your will.



  • Radio/Cost of Living

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Surprise results when young Christians are godly

How a team of young Christians’ actions and love for each other can impact other people.




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When God leads the way

A group of people open to the Holy Spirit's leading find an open door for ministry in Nazareth.




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"When I grow up"

OM Guatemala and volunteers visit Tiquisate to share about God's love in eight public schools.




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When discipleship and ministry collide

During the OM's Ride 2 Transform 2017 cycle tour, 17 cyclists biked 550 kilometres around southern Malawi, distributing AudioBibles and praying.




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Trusting God when it hurts

Mexico City, Mexico :: A crewmember on a ministry team in Mexico City meets a faith-filled teenager with an inspiring testimony.




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The way I see it  - When it means what it says

It matters not if we are from 200 countries; we are one in Christ and shall be for eternity. OMNI-team member Greg Kernaghan about ‘globalisation’.




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News24 Business | MONEY CLINIC | What are my rights and responsibilities when it comes to insurance?

Wynand van Vuuren, client experience partner at King Price insurance, unpacks the rights and responsibilities of a consumer when it comes to insurance.




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When the Rubber Hits the Road

Profile of a veteran driver with OM EAST




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When caring for the needy means us

"In order to fulfil our mandate, there are several needs we must invest in," says Stephan Bauer.




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How to Make Lessons Cohesive When Teaching Both Remote and In-Person Classes

When some students are online and others in school buildings, how can teachers make sure everyone is learning what they need to learn?