A system and method for making a layered dental appliance. The system can include a first portion comprising a negative of a first layer of a layered dental appliance, and a second portion comprising a positive shape of a second layer of the layered dental appliance. The method can include providing a mold comprising a negative of an outer shape of a layered dental appliance, and positioning a slurry in the mold, forming a first layer of the layered dental appliance. The method can further include providing a solid structure comprising a positive shape of a second layer of the layered dental appliance, and pressing the solid structure into the slurry in the mold.

Discrete micro and nanoscale particles are formed in predetermined shapes and sizes and predetermined size dispersions. The particles can also be attached to a film to form arrays of particles on a film. The particles are formed from molding techniques that can include high throughput and continuous particle molding.

A spray-drying apparatus includes a drying chamber that has a first end, a second end, and at least one side wall extending between the first and second ends to define an interior of the drying chamber having a center axis. A nozzle can be positioned at the first end of the drying chamber and be configured to atomize liquid and spray the atomized liquid into the interior of the drying chamber at a maximum spray pattern angle relative to the center axis. A ratio of the length between the first end and second end to a maximum width between opposing internal surfaces of the interior of the drying chamber can be at least 5 to 1.

Systems and methods are provided for generating a composite video based on a plurality of asynchronously recorded input video streams. A plurality of segments of the input video streams are identified. A number of the input video streams that were recording during the particular segment are determined. A video display configuration for the particular segment is determined based on the number of video streams that were recording, where the video display configuration includes a display sub-region for each of the number of video streams that was recording. A composite video is generated, where the composite video includes a portion of video associated with each of the segments, where the composite video portion associated with the particular segment is formatted according to the video display configuration and displays the video streams that were recording during the particular segment in the display sub-regions of the video display configuration.

Recording reconstruction from multiple overlapping recordings may be provided. New recorders may copy manifests from working recorders, as opposed to reconstructing from failed recorders, to construct manifests that refer to video fragments from different recorders. Origin servers may follow these reconstructed manifests to obtain any fragment in the recording, in any combination of recorder failure/take-over/restart, as long as there was at least one recorder functioning at all times.

Systems and methods to position and play content. The system renders a first content segment to an output device at an accelerated speed for the first content segment. Next, the system receives a request to play the first content segment from the beginning of the first content segment at a normal speed for the first content segment. Next, the system automatically positions to the beginning of the first content segment based on position information that is associated with the first content segment. Finally, the system renders the first content segment to the output device from the beginning of the first content segment at a normal speed for the first content segment.

Low profile reamers and methods of use are provided which can, in general, allow a hole to be drilled in bone. In one embodiment, a low profile retractable bone reamer is provided having an elongate shaft with a cutting element disposed on a distal end of the elongate shaft that can be configured to drill a hole in bone. The elongate shaft and cutting element can have first and second longitudinally separated portions that are movably coupled to each other. The reamer can be configured to move between a retracted configuration, in which a the reamer has a reduced, low profile configuration, and a non-retracted configuration, in which both longitudinally separated portions of the cutting element can be positioned adjacent to one another to form a single cutting element.

Illustrative embodiments of force sensitive input devices and methods are disclosed. In at least one embodiment, an input device may comprise a first input key configured to output a first analog signal as a function of force applied to the first input key, a second input key configured to output a second analog signal as a function of force applied to the second input key, a third input key configured to output a third analog signal as a function of force applied to the third input key, a fourth input key configured to output a fourth analog signal as a function of force applied to the fourth input key, and a controller configured to output movement data including both direction and magnitude in response to the first, second, third, and fourth analog signals, where the movement data is formatted for presentation to a driver of a computing device.

A method for calibrating (700) an antenna array comprises a plurality of antenna elements coupled to a plurality of respective receive paths in a wireless communication system. The method comprises, in receive mode, applying a test signal to an individual single receive path (715) of the plurality of receive paths; and feeding back the test signal via a switched coupler network. The method further comprises running a receive calibration measurement routine to determine at least one measurement value used to calibrate the individual signal receive path and waiting for at least one converged measurement value; and extracting (720) the converged measurement value for at least one individual receive path. The steps of applying, running, extracting for a next individual single receive path are repeated until the calibration routine has completed (725). The method further comprises selecting a converged measurement value of at least one individual receive path from a plurality of receive paths (730) to form a reference receiver calibration result (730); normalizing a plurality of at least one measurement values of the plurality of receive paths using the reference receiver calibration result (730); and applying a normalized value to at least one of the plurality of receive paths.

Devices, systems, and methods for sending positional information from transmitters/beacons are disclosed. In one implementation a transmitter generates a range block including a ranging signal and a hybrid block including positioning data, and sends the range block and hybrid block in predefined slots in a transmit frame. A receiver in a user device receives signals from a plurality of transmitters and generates position/location information using trilateration and measured altitude information in comparison with transmitter altitude information.

A system and method of identifying changes utilizing radio frequency polarization includes receiving a reflected and/or transmitted polarized radio frequency signal at a receiver, filtering, amplifying and conditioning the received signal, converting the received signal from an analog format to a digital format, processing the digital signal to elicit a polarization mode dispersion feature of the received signal, and comparing the polarization mode dispersion features to a known calibration to detect a change in a characteristic of the target object.

A system for determining a coverage region of a radar device is disclosed. The system may have one or more processors and a memory. The memory may store instructions that, when executed, enable the one or more processors to receive radar data generated by a radar device and lidar data generated by a lidar device. The radar data may include radar data points representing objects detected by the radar device and the lidar data may include lidar data points representing objects detected by the lidar device. The one or more processors may be further enabled to determine a radar coverage region for the radar device by comparing one or more radar data points to one or more lidar data points, and to generate data used to display a graphical representation of the radar coverage region.

A phased array transmitter includes a plurality of vector modulators, an in-phase/quadrature (I/Q) signal generator, and a multiphase generator. The output phases of the plurality of vector modulators, and hence the direction of transmission of the phased array transmitter, are set and controlled by adjusting both the magnitude ratios of I/Q signal pairs generated by the I/Q signal generator and applied to I and Q inputs of the plurality of vector modulators and phases of a plurality of local oscillator (LO) signal phases generated by the multiphase generator and applied to LO inputs of the plurality of vector modulators. Setting and controlling the output phases of the vector modulators by varying both the magnitude ratios of the I/Q signal pairs and the phases of the LO signal phases allows the output phases of the plurality of vector modulators to be more precisely set and controlled than if the output phases were to be set and controlled only through the LO paths or only through the I/Q signal paths of the plurality of vector modulators.

A positive response notification to provide information regarding locate and/or marking operations for underground facilities may include time-stamp information to provide proof of a time at which the locate and/or marking operation was completed by a locate technician, and/or place-stamp information to provide proof of a presence of the locate technician at or near a work site. An electronic manifest image and/or a virtual white line image similarly may be included in a positive response notification. In one example, such images may be bundled together based on respective descriptor files (or descriptor metadata) that associates the corresponding images with a locate request ticket for the operation. In another example, a positive response notification may include environmental information regarding one or more environmental conditions present at or near the work site during the locate and/or marking operation.

Embodiments include systems and methods of powering a mobile device using a sink device. The method may include detecting a coupling of the mobile device to the sink device and transmitting an acknowledgement in response to a query, the acknowledgement confirming that the sink device has charging capability. Power may be selectively provided in response to the power request. According to some embodiments, the method includes transmitting a query by a communications transmitter to determine if a sink device has charging capability, and deactivating a driver for a power line and transmitting a power request using the communications transmitter in response to receiving an acknowledgement signal from the sink device. The method may further include selectively providing power received from the sink device to a charging circuit of the mobile device. The mobile device may include an HDMI transmitter for communicating through a transmission line to an HDMI sink device.

Methods and systems for a go/no-go Landing Decision Point (LDP) are disclosed. The methods and systems provide a graphical LDP on a cockpit display that pilots can use to determine whether to continue the landing or execute a go-around. The methods and systems may be implemented in embodiments having an onboard portion, an off-board portion, or both operatively coupled to provide an LDP in a preview/planning mode and real time mode.

Systems and methods disclosed herein may be useful emergency braking systems for use in, for example, an aircraft. A system is disclosed that allows emergency braking without the need for a manually operated emergency brake. For example, a system is provided comprising a potentiometer in mechanical communication with a brake pedal, a first electronic switch in electrical communication with the potentiometer, a second electronic switch indicating a displacement of the brake pedal, wherein a brake control valve opens in response to the first electronic switch, and wherein a shutoff valve opens in response to the second electronic switch.

A method for monitoring input power to an electronically commutated motor (ECM) is described. The method includes determining, with a processing device, an average input current to the motor, the average input current based on a voltage drop across a shunt resistor in series with the motor, measuring an average input voltage applied to the motor utilizing the processing device, multiplying the average input current by the average voltage to determine an approximate input power, and communicating the average input power to an external interface.

In some aspects, an unloading device for a pipe processing system includes a depositing carriage having a depositing surface for depositing a pipe during and/or after a pipe processing operation, the depositing carriage being configured to move in a longitudinal direction of the pipe, and a supporting carriage having a supporting member for the pipe, the supporting member having a wall for radially supporting the pipe, and the supporting carriage being configured to move in a longitudinal direction of the pipe, where the depositing surface of the depositing carriage and/or the supporting member of the supporting carriage is configured to move in at least one other direction in addition to the longitudinal direction of the pipe so that the depositing carriage and the supporting carriage can be at least partially moved past each other along the longitudinal direction of the pipe.

Boom drive apparatus for substrate transport systems and methods are described. The boom drive apparatus is adapted to drive one or more multi-arm robots rotationally mounted to the boom to efficiently put or pick substrates. The boom drive apparatus has a boom including a hub, a web, a first pilot above the web, and a second pilot below the web, a first driving member rotationally mounted to the first pilot, a second driving member rotationally mounted to the second pilot, a first driven member rotationally mounted to the boom above the a web, a second driven member rotationally mounted to the boom below the a web, and a first and second transmission members coupling the driving members to driven members located outboard on the boom. Numerous other aspects are provided.

Reinforcement devices and systems for holding a traffic control assembly in compression are provided. The traffic control assembly includes a traffic signal disconnect hanger and/or a traffic signal and a first span wire positioned above the traffic control assembly. In some embodiments, the reinforcement device includes an upper support device connected to the first span wire where the upper support device has a length that is greater than a width of the traffic control assembly and the upper support device is configured to spread the load of the traffic signal assembly to the first span wire. The reinforcement device includes a lower support device operably connected to the traffic signal, a first vertical support member, and a second vertical support member where the first and second vertical members are tensioned when the upper support device, the lower support device and the first and second vertical support members are connected together.

Disclosed are methods and systems for the analysis of testosterone in a sample using supported liquid extraction and liquid chromatography-mass spectrometry.

An improved analytical method for analysis of dianhydrogalactitol preparations provides a method for determining the purity of dianhydrogalactitol and detecting impurities in preparations of dianhydrogalactitol, as well as identifying any such impurities. The method employs high performance liquid chromatography (HPLC), in particular, HPLC with evaporative light scattering detection (ELSD); the HPLC can be followed by tandem mass spectroscopy. The method can further comprise the step of performing preparative HPLC collection of at least one specific substance peak present in a preparation of dianhydrogalactitol.

Microfluidic devices having a protein renaturation component and methods for using the same are provided. Aspects of the present disclosure include microfluidic devices that include a separation medium with a first flow path and a protein renaturation component in fluid communication with the separation medium and having a second flow path. Also provided are methods of using the devices as well as systems and kits that include the devices. The devices, systems and methods find use in a variety of different applications, including diagnostic and validation assays.

A molecularly imprinted polymer (MIP) sensor including a substrate, two or more electrodes, a conductive layer applied to the substrate and a molecularly imprinted polymer layer applied to the conductive layer is disclosed herein The MIP sensor may form part of an MIP sensor system that can be used to detect and quantify target molecules.

The invention describes biomarkers which can be used to predict the likelihood that an individual will develop Diabetes. The biomarkers can also be used to screen large groups in order to identify individuals at risk of developing Diabetes.

A two step lateral flow assay method for identifying IgE antibodies in a sample comprises applying a sample to a sample port of a device, wherein the device is adapted to deliver the sample to a lateral flow matrix having a plurality of IgE antigen species immobilized at respective positions at a first location; allowing the sample to travel along the lateral flow matrix through the immobilized plurality of IgE antigen species to a second location downstream of the first location; and, after a predetermined period of time, applying liquid buffer to the lateral flow matrix to mobilize labeled reagent which is adapted to bind anti-IgE antibody and which is dried on the lateral flow matrix at a location upstream of the sample port delivery of the sample to the lateral flow matrix, and allowing labeled reagent mobilized by the liquid buffer to travel along the lateral flow matrix through the immobilized plurality of IgE antigen species and bind with any IgE antibody bound to the immobilized IgE antigen species, and to travel to a second location downstream of the first location where the mobilized labeled reagent causes a visible change to occur at the second location.

Fluorescent pH detector and methods for measuring pH using the fluorescent pH detector.

Disclosed herein are antibody-nanoparticle conjugates that include two or more nanoparticles (such as gold, palladium, platinum, silver, copper, nickel, cobalt, iridium, or an alloy of two or more thereof) directly linked to an antibody or fragment thereof through a metal-thiol bond. Methods of making the antibody-nanoparticle conjugates disclosed herein include reacting an arylphosphine-nanoparticle composite with a reduced antibody to produce an antibody-nanoparticle conjugate. Also disclosed herein are methods for detecting a target molecule in a sample that include using an antibody-nanoparticle conjugate (such as the antibody-nanoparticle conjugates described herein) and kits for detecting target molecules utilizing the methods disclosed herein.

Devices for attaching a sheet-like implant to a target tissue include a sheath and a staple push rod. The sheath has a distal end configured to be pressed against the target tissue. The staple push rod is disposed within at least a portion of the sheath and is slidable relative thereto. The staple push rod includes a pair of stakes. Each stake is dimensioned to abut a surface of a staple to apply pushing forces thereto. The stakes are biased to assume a bow-like shape such that an intermediate portion of a staple extends tautly between the first stake and the second stake when the stakes are extending beyond the distal end of the tubular member. Methods for attaching a sheet-like implant to a target tissue are also disclosed.

A device for attaching a sheet-like implant to a target tissue. The device includes a fastener push rod including a first portion, a second portion and a force limiting mechanism operably coupled between the first portion and the second portion. A fastener is carried by the second portion of the fastener push rod. The force limiting mechanism transmits longitudinal movement of the first portion to the second portion while the forces applied to the fastener by the fastener push rod are less than a predetermined value such that longitudinal movement of the first portion of the fastener push rod causes substantially equivalent longitudinal movement of the second portion. The force limiting mechanism allows relative longitudinal motion between the first and second portions while the forces applied to the fastener are equal to or greater than the predetermined value such that the application of undue forces to the fastener is prevented.

Devices and methods are provided for forming and securing a tissue plication. More particularly, the devices and methods of the present invention can be used to create multiple tissue folds on an anterior and posterior wall of a stomach cavity to reduce the volume thereof. In one aspect, a method of acquiring and fixating tissue is disclosed that includes inserting a surgical device having first and second jaws and a tissue acquisition member into a body lumen, positioning the device in a first position in which the jaws extend substantially parallel to a tissue surface, drawing tissue through the jaws by moving the tissue acquisition member away from the jaws, and driving at least one fastener through the tissue disposed between the jaws.

Compositions and methods for inhibiting and controlling the growth of microbes are disclosed. The composition comprises at least one chemically-modified peptide with antimicrobial activity and at least one carrier. The method comprises of administering an amount, effective for the prevention, inhibition and termination of microbial growth for industrial, pharmaceutical, household and personal care use.

Devices capable of deterring or preventing bulk extraction of drugs from, for example, drug-delivery systems are exemplarily disclosed. In one embodiment, such a device may include a package releasably retaining a drug and an agent. The agent is configured to suppress a physiological effect of the drug when the agent contacts the drug or is coadministered with the drug. The cell package is configured such that an amount of the drug is selectively releasable with respect to the agent when the package is operably proximate to an encoded key. The package, however, may be configured to impose a relatively high likelihood that either the drug will not be accessed or the drug will be contaminated by the agent if access to the contents of the package is sought without the use of an encoded key.

A method of enabling administration of a drug includes determining, within a drug-transfer device including cells, a location of at least one cell and generating information identifying the determined location. A user may be provided with the drug-transfer device. The drug is retained within the at least one cell when the user is provided with the drug-transfer device. The method also includes encoding a key with the information and providing the user with the key before, after or when the user is provided with the drug-transfer device. Drug retained within the at least one cell is selectively releasable when the key is operably proximate to the drug-transfer device and is encoded with the information. The key can be encoded with the information before and/or after being provided to the user. In some embodiments, the key is encoded based on instructions transmitted over a network.

An apparatus for forming a single extrudable food stream such as a cooked cereal dough into a plurality of differently colored and/or flavored dough streams is disclosed including an extruder having screw augers for advancing a plastic food mass, a head or manifold for dividing the plastic food mass into a plurality of substreams each in turn in fluid communication with a plurality of sub-divided dough passageways, and a die head having a plurality of die ports. Each subpassage is separately supplied an additive and has disposed therein a multiplicity of in-line static mixer elements to admix the additive into the substreams of the plastic food mass before passage through the die ports. In a preferred form, first and second substreams are intermixed in a non-homogenous manner before reaching the exit ports. The extrudates are severed into individual pieces by a rotary cutter.

Disclosed are novel processing methods for green coffee beans that result in novel green coffee bean products, including products that incorporate whole green coffee beans. Methods include selecting whole coffee beans in their fresh green unroasted state with naturally-occurring levels of phytonutrients, sterilizing and drying them, applying iterative grinding processes and stabilization techniques, all while avoiding high temperatures. Whole green coffee bean products created and defined by these methods have unexpectedly been found to increase focus and concentration in users, and are believed useful in the treatment of attention and concentration deficits and related disorders, such as attention deficit (AD), attention deficit disorder (ADD), attention deficit hyperactivity disorder (ADHD), and various related and/or comorbid disorders.

The invention generally provides novel no-bake grain products and methods of preparation of the same. Specifically a no-bake food product with a toasted appearance and flavor and a method of providing a toasted appearance and flavor to a no-bake food product. The no-bake food product includes granola bars, clusters, cereal, instant hot cereal and snacks.

Isolated wheat proteins that are substantially free of sulfites and compositions formed from the isolated wheat proteins are described. Methods of forming compositions which include isolated wheat proteins that are substantially free of sulfites are also described.

The present invention provides stabilized oil-in-water emulsions with an extended range of chemical, thermal and/or mechanical stabilities, and method(s) for their preparation. Such preparations provide an environmentally-protective biopolymer component exhibiting improved adherence to the dispersed phase, reducing or eliminating dissociation therefrom under such conditions, for use in the context of a range of food, pharmaceutical, personal care, health care, cosmetic and other end-use applications.

In order to solve the numerous problems with existing steam, vacuum, and hot water heating systems, presented are novel systems and methods of vapor vacuum heating having several improvements over the prior art, including: condensate return which can operate without steam traps; naturally-induced vacuum; improved vacuum pump operation for sustaining vacuum in such systems; liquid lift apparatus for use with such systems; and other improvements. All innovations presented herein make vapor vacuum heating more efficient and economical for industrial, commercial, and home applications. A field test conducted with these innovations show results of about 26-50% reduced energy usage, implying significant energy savings from the use of the present invention over current heating systems.

Deliquefication systems with an upper pumping section for discharging fluid pumped to it by a lower pumping section; in one aspect, for providing liquid from a wellbore to the upper section for removal of the liquid from the wellbore; and, in one aspect, such systems for dewatering a gas well. This abstract is provided to comply with the rules requiring an abstract which will allow a searcher or other reader to quickly ascertain the subject matter of the technical disclosure and is submitted with the understanding that it will not be used to interpret or limit the scope or meaning of the claims, 37 C.F.R. 1.72(b).

An electronic system for enhancing camera focusing on a portable electronic device is disclosed. The system comprises a body, a bus, and a camera module coupled to the bus and comprising a photosensitive substrate and a lens assembly wherein the lens assembly comprises a lens capable of being selectively moved to a distance from the photosensitive substrate for light focus thereon. Further, it comprises an accelerometer coupled to the bus and configured to generate orientation information, said orientation information indicating contemporaneous orientation of the body with respect to a predetermined reference. It also comprises a memory and a processor coupled to the bus. The memory comprises instructions that when executed implement an autofocus program configured to automatically determine the distance based on: 1) image data captured by said camera module; and 2) the orientation information generated by the accelerometer.

In some embodiments, a kit includes a slide device and an action figure coupled to the slide device. The kit also includes a tool configured to modify a shape of a base material such that a path that has a non-zero height is defined within the base material. The action figure and the slide device can collectively slide down at least a portion of the path when disposed on the path. The base material can be, for example, snow or sand. In some embodiments, the tool can include tool body having a length dimension, a width dimension and a height dimension. The length dimension can be greater than the width dimension and the height dimension can be greater than at least half a height dimension of the slide device and the action figure collectively. A handle can be coupled to the tool body.

The present invention relates to moldable sand compositions, methods for making the moldable sand compositions, and methods for using the moldable sand compositions. In a particular embodiment, the moldable sand composition comprises between about 70% to about 95% sand, between about 5% to about 30% water, a polar polymeric resin, a crosslinking agent, and a humectant. In an exemplary embodiment, the composition contains no oils, waxes, glycols, or rubbers. The composition is capable of becoming hardened over time in order to maintain the achieved shape, and can be re-wetted and molded again after becoming hardened.

A microlaser system includes an optical source, a microlaser, an actuator switch, and a photovoltaic power source. The microlaser, which includes a control element, is optically pumped by at least a portion of light emitted by the optical source. The actuator switch is configured to be activated by a triggering event. Furthermore, the photovoltaic power source is coupled in a series connection with the actuator switch and the control element, the series connection configured to connect the photovoltaic power source to the control element of the microlaser when the actuator switch is activated by the triggering event.

Bushing assemblies include a first tubular end portion, a second tubular end portion, and a middle tubular portion. The middle tubular portion has a longitudinal compressive strength that is less than that of the end portions. In some embodiments, the middle tubular portion is constructed of braided sleeving. Also disclosed are bushing assembly kits, apparatuses that include bushing assemblies, such as aircraft, and associated methods of utilizing bushing assemblies.

A nut assembly and a holddown assembly using the nut assembly are described, including methods of manufacture and assembly. The nut assembly may include a body portion having first and second openings with an internal wall extending between them. A rotation-inhibiting wall may be included between the first and second openings. A nut portion configured to move axially within the internal wall of the body portion includes structures for co-acting with a rotation-inhibiting wall to limit or prevent rotation of the body portion and the nut portion relative to each other. A nut portion and a body portion extending around the nut portion have limited axial movement relative to each other due to axial engagement between adjacent surfaces on the nut portion and the body portion.

Panel fasteners, panel assemblies, methods of assembly and installation of panel assemblies and panel fasteners, anchor systems, anchor systems with captive fasteners and assemblies are disclosed.

Methods, systems and devices are provided for displaying monitored activity data in substantial real-time on a screen of a computing device. One example method includes capturing motion data associated with activity of a user via an activity tracking device. The motion data is quantified into a plurality of metrics associated with the activity of the user. The method includes connecting the activity tracking device with a computing device over a wireless data connection, and sending motion data from the activity tracking device to the computing device for display of one or more of the plurality of metrics on a graphical user interface of the computing device. At least one of the plurality of metrics displayed on the graphical user interface is shown to change in substantial real-time based on the motion data.