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'We had to leave'

OM writer Ellyn shares firsthand accounts from those who fled for their lives to Bangladesh and now reside with thousands in camps in Cox’s Bazar.




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Fin24.com | Sars may leave no good deed unpunished

Don't make the mistake of thinking that the money your company spends on social upliftment is automically tax deductible.




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Twinkle Khanna's "Mother's Day" Monologue Will Leave You In Splits

"What mothers really want for mother's day but can't tell their kids," wrote Twinkle




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Oyo cuts salary, sends employees on leave

Oyo’s consolidated losses increased to $335 million in the year to March 2019 from $52 million in FY18 as expansion into international markets, including key market China entailed heavy costs.




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Highest mortality, low testing: Central team’s note to Bengal as it leaves state

While praising the state on some counts, including increasing daily testing from 400 to 2,410 per day between April 20 and May 2, it also flagged the non-cooperation of the state bureaucracy.




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'I like to face guys that have COUNTRIES behind them': Floyd Mayweather leaves door open to Khabib, McGregor boxing bouts (VIDEO)

While he says he has no interest in facing a top-ranked boxer, Floyd Mayweather is refusing to rule out a fight with the likes of Conor McGregor or Khabib Nurmagomedov, as long as the money is right.
Read Full Article at RT.com




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Riots Valorant leaves plenty of room for CSGO in the competitive tactical shooter scene




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Coronavirus: Tourist centres in Tamil Nadu under lockdown; visitors in Ooty asked to leave within 24 hours

Tamil Nadu has so far reported only one COVID-19 case and the 45-year old man unuder treatment in Chennai has recovered and two subsequent tests returned negative.




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S&P settlement leaves future unclear for ratings

It cost $1.37 billion, but Standard & Poor’s finally seems to have closed the darkest chapter in its 150-year history as a rating agency.




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Medical leave

A person who is enrolled in State Government job he continued his service 6 yrs, unfortunately he met accident he need bed rest for two to three. is that such term leaves are available,or they terminated from service ,so please advise what to do next seeking your response




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IndiGo to implement wider pay cuts, send some staff on leave without pay

While senior-vice presidents and above would have 20% of their pay slashed, vice-presidents and cockpit crew would take a 15% cut.




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Mystery Of The Missing Pound: TikTok Puzzle Leaves Internet Baffled

In the video, a TikTok user challenges viewers to solve the mystery of the missing pound while splitting a restaurant bill equally.




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Wipro Can Fire Employees, Enforce Unpaid Leaves To Save Costs; Hiring Will Not Stop

India’s leading IT firm Wipro has said that firing employees can be considered in the coming days, in order to save costs. Employees can be asked to go on unpaid leaves as well. However, the silver lining is that, hiring won’t be stopped. Wipro: Business Hit Due To Coronavirus Wipro declared their 4th quarter earnings, […]

The post Wipro Can Fire Employees, Enforce Unpaid Leaves To Save Costs; Hiring Will Not Stop first appeared on Trak.in . Trak.in Mobile Apps: Android | iOS.




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IC Packagers: You Can Leave Your (Molding) Cap On…

Molding caps aren’t something we talk about too frequently around here. We all know they exist, and they serve an important purpose of protecting the delicate die from potentially harsh environmental conditions. They impact how well heat can be...(read more)



  • Allegro Package Designer

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Apache ActiveMQ Flaws Leave Servers Open To DoS Attacks





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Design Flaw Leaves Bluetooth Devices Vulnerable






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Packet Storm Exploit 2013-0813-1 - Oracle Java IntegerInterleavedRaster.verify() Signed Integer Overflow

The IntegerInterleavedRaster.verify() method in Oracle Java versions prior to 7u25 is vulnerable to a signed integer overflow that allows bypassing of "dataOffsets[0]" boundary checks. This exploit code demonstrates remote code execution by popping calc.exe. It was obtained through the Packet Storm Bug Bounty program.




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Packet Storm Advisory 2013-0813-1 - Oracle Java IntegerInterleavedRaster.verify()

The IntegerInterleavedRaster.verify() method in Oracle Java versions prior to 7u25 is vulnerable to a signed integer overflow that allows bypassing of "dataOffsets[0]" boundary checks. This vulnerability allows for remote code execution. User interaction is required for this exploit in that the target must visit a malicious page or open a malicious file. This finding was purchased through the Packet Storm Bug Bounty program.





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A modern Cinderella story: California’s record on wholesale distributed generation leaves much room for improvement

California, long a progressive leader on renewable energy and climate change mitigation, has neglected a key market segment for renewable energy: the “community-scale,” or “wholesale distributed generation” (DG), market. This market segment is defined as projects below 20 megawatts that connect to the distribution grid and export power to the grid for sale.




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Fifth GE wind turbine collapse leaves worker injured

A utility worker at the Delta 6 wind park in Brazil has been injured following yet another collapse of a General Electric (GE) turbine, bringing the total number of turbines to have failed in the America’s to five in 2019.

 




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RGGI Chair Says States Won’t Leave Emissions Trading Market for California, Quebec

California and Quebec, which together created the largest carbon market in North America this year, may come away empty-handed as they woo northeastern U.S. states to join their system.





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Fifth GE wind turbine collapse leaves worker injured

A utility worker at the Delta 6 wind park in Brazil has been injured following yet another collapse of a General Electric (GE) turbine, bringing the total number of turbines to have failed in the America’s to five in 2019.

 




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RGGI Chair Says States Won’t Leave Emissions Trading Market for California, Quebec

California and Quebec, which together created the largest carbon market in North America this year, may come away empty-handed as they woo northeastern U.S. states to join their system.




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Coronavirus – Emergency volunteering leave - UK

Updated 30/3/20 The Coronavirus Act 2020 was enacted on 26/3/20 and introduces a new statutory emergency volunteering leave, to support health and social care authorities. The Act’s provisions on volunteering leave are expected to be implement...




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IHC HR e-briefing 114 - Uncertainty over future of paternity leave

Comments made in Parliament yesterday by Theresa May, Minister for Women and Equalities, suggest that regulations introduced by the Labour government to extend paternity leave for fathers could be postponed and, ultimately, rewritten by the coalitio...




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Shramik train leaves Coimbatore for UP's Akbarpur

(MENAFN - IANS) Chennai, May 9 (IANS) A Sharmik special train left for Akbarpur in Uttar Pradesh on Saturday evening from the Coimbatore railway s... ......




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Being ostracized: Virus leaves its mark for UK's elderly

LONDON (AP) — From resounding applause to ostracization and isolation. That's essentially the journey Lt. Cmdr. Robert Embleton, who served 34 years in Britain's Royal Navy, took by ambulance when discharged from Derriford Hospital in Plymouth, southwestern England, on April 8 following his near-month sickness with COVID-19. Arriving at his retirement home, he immediately went into self-isolation with his wife of 55 years, Jean, who has shown no symptoms of the virus. Soon after, Embleton realized he was carrying some new baggage — the stigma of the virus. He even considered buying a bell to warn of his presence. “I was regarded as a sort of leper, a plague carrier. Some people when they...




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Being ostracized: Virus leaves its mark for UK's elderly

Stars and Stripes is making stories on the coronavirus pandemic available free of charge. See other free reports here. Sign up for our daily coronavirus newsletter here. Please support our journalism with a subscription. LONDON — From resounding applause to ostracization and isolation. That's essentially the journey Lt. Cmdr. Robert Embleton, who served 34 years in Britain's Royal Navy, took by ambulance when discharged from Derriford Hospital in Plymouth, southwestern England, on April 8 following his near-month sickness with COVID-19. Arriving at his retirement home, he immediately went into self-isolation with his wife of 55 years, Jean, who has shown no symptoms of the virus. Soon after,...




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Being ostracized: Virus leaves its mark for UK’s elderly

LONDON (AP) — From resounding applause to ostracization and isolation. That’s essentially the journey Lt. Cmdr. Robert Embleton, who served 34 years in Britain’s Royal Navy, took by ambulance when discharged from Derriford Hospital in Plymouth, southwestern England, on April 8 following his near-month sickness with COVID-19. Arriving at his retirement home, he immediately went into self-isolation with his wife of 55 years, Jean, who has shown no symptoms of the virus. Soon after, Embleton realized he was carrying some new baggage — the stigma of the virus. He even considered buying a bell to warn of his presence. “I was regarded as a sort of leper, a plague carrier. Some people...




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Israel: Bennett leaves the army after approving a number of serious settlement projects

The settlement report said that in strange and reprehensible statements that reflect the Zionist colonial and racist ideology, the American ambassador to Israel, David Friedman, urged the government of Benjamin Netanyahu and Benny Gantz to accelerate the announcement of the annexation of areas in the occupied West Bank to Israel. He told an Israeli newspaper that “if the government of Israel announces this, the United States will be prepared to recognize, in the coming weeks, Israel’s sovereignty over the Jordan Valley and Israeli settlement in Judea and Samaria, and that it will recognize 30% of the occupied West Bank as areas of Israel within the deal of the century in the...




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Education ebriefing – Statutory parental bereavement leave and pay to commence in April 2020

Background The Parental Bereavement (Leave and Pay) Act 2018 received Royal Assent as long ago as 13 September 2018. The intention was the Act would come into force in 2020, with further clarification on the provisions to be contained in regulations...




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Education briefing - Coronavirus - Emergency volunteering leave

The Coronavirus Act 2020 has now been enacted and introduces a new statutory emergency volunteering leave, to support health and social care authorities. Health and social care workforces are under increasing pressure in providing services during th...




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U.S. Military Operations Leave 132 Civilians Dead in 2019

[Dalsan Radio] US military operations in four countries in 2019 left 132 civilians dead, according to a report released Wednesday by the Pentagon.




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Taylor: I want to leave with lasting legacy

Katie Taylor has Amanda Serrano, Delfine Persoon and Cecilia Braekhus on her radar as the Irish fighter looks to leave behind a legacy that will stand the test of time.




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Kipchoge-led Nike leave rivals playing catch-up in marathon shoe wars

The Covid-19 outbreak could favour Nike, Metzler argues.




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Refugee children leave Greece to settle in Luxembourg

A group of 12 is the first of more than 1000 relocations being expedited amid concerns over the impact of coronavirus on vulnerable groups.




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Russia celebrates Victory Day as lockdown leaves Moscow deserted

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U.S. E-Cigarette Maker to Leave Korea as Health Fears Hit Sales

U.S. electronic cigarette maker Juul Labs is pulling out of the Korean market just a year after its launch here amid health concerns over its products.The company announced on Wednesday, "We decided to stop operations in Korea, and have notified sellers here."Launched in the U.S. in 2015, Juul, a li...




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Mum and newborn leave hospital after beating COVID-19

A mother who was given a 50 percent survival chance and her newborn baby were discharged from hospital on Monday (May 4) after both fighting COVID-19.




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Routine Ear Wax 'Flush' Leaves Woman's Face Paralyzed

Title: Routine Ear Wax 'Flush' Leaves Woman's Face Paralyzed
Category: Health News
Created: 12/19/2019 12:00:00 AM
Last Editorial Review: 12/20/2019 12:00:00 AM




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Cervical Cancer May Leave Lasting Imprint on Survivors

Title: Cervical Cancer May Leave Lasting Imprint on Survivors
Category: Health News
Created: 5/5/2017 12:00:00 AM
Last Editorial Review: 5/5/2017 12:00:00 AM




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Raking Your Leaves to the Edge of Your Yard an Invitation to Ticks

Title: Raking Your Leaves to the Edge of Your Yard an Invitation to Ticks
Category: Health News
Created: 3/22/2020 12:00:00 AM
Last Editorial Review: 3/23/2020 12:00:00 AM




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Many Seniors Leave Hospital With New Disabilities

Title: Many Seniors Leave Hospital With New Disabilities
Category: Health News
Created: 3/2/2020 12:00:00 AM
Last Editorial Review: 3/3/2020 12:00:00 AM




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Glycoprotein 5 Is Cleaved by Cathepsin E during Porcine Reproductive and Respiratory Syndrome Virus Membrane Fusion [Virus-Cell Interactions]

Porcine reproductive and respiratory syndrome (PRRS) is a serious viral disease affecting the global swine industry. Its causative agent, PRRS virus (PRRSV), is an enveloped virus, and therefore membrane fusion between its envelope and host cell target membrane is critical for viral infection. Though much research has focused on PRRSV infection, the detailed mechanisms involved in its membrane fusion remain to be elucidated. In the present study, we performed confocal microscopy in combination with a constitutively active (CA) or dominant negative (DN) mutant, specific inhibitors, and small interfering RNAs (siRNAs), as well as multiple other approaches, to explore PRRSV membrane fusion. We first observed that PRRSV membrane fusion occurred in Rab11-recycling endosomes during early infection using labeled virions and subcellular markers. We further demonstrated that low pH and cathepsin E in Rab11-recycling endosomes are critical for PRRSV membrane fusion. Moreover, PRRSV glycoprotein 5 (GP5) is identified as being cleaved by cathepsin E during this process. Taken together, our findings provide in-depth information regarding PRRSV pathogenesis, which support a novel basis for the development of antiviral drugs and vaccines.

IMPORTANCE PRRS, caused by PRRSV, is an economically critical factor in pig farming worldwide. As PRRSV is a lipid membrane-wrapped virus, merging of the PRRSV envelope with the host cell membrane is indispensable for viral infection. However, there is a lack of knowledge on its membrane fusion. Here, we first explored when and where PRRSV membrane fusion occurs. Furthermore, we determined which host cell factors were involved in the process. Importantly, PRRSV GP5 is shown to be cleaved by cathepsin E during membrane fusion. Our work not only provides information on PRRSV membrane fusion for the first time but also deepens our understanding of the molecular mechanisms of PRRSV infection, which provides a foundation for future applications in the prevention and control of PRRS.




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Robot with origami leaves can follow the sun like a real plant

A robot can recreate the mechanism plants use to transport water to bend itself towards the sun and open its leaves like a real plant