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Centre’s nod sought for Vizag Metro, MA&UD Minister informs A.P. Assembly

The revised cost estimate stands at ₹17,232 crore; the project is initially proposed to come up in two phases with four corridors spanning a total length of 76 km




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New road proposed from IIT-Tirupati campus to Rachagunneri

Rachagunneri is home to the massive 400/220/132kV electrical substation and also a private steel plant




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PAG report points out Andhra Pradesh govt.’s failure to disclose quantum of off-budget borrowings in Budget

Principal amount outstanding in 2019-20 was ₹67,171 crore, and it touched ₹1,54,797 crore in 2023-24, says the PAG report released by the I&PR Department




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Jagan dares govt. to arrest him, says will continue to ‘expose failures’




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Police book Sri Reddy for posting ‘defamatory content’ against Chandrababu Naidu, Pawan Kalyan




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Supreme Court sets pan-India guidelines against ‘bulldozer justice,’ calls demolitions without due process unconstitutional

The Apex court maintains that these guidelines do not apply in cases of unauthorized public land construction or where demolition is mandated by a court ruling




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Doctors believe continual upskilling is crucial for diabetes management: survey

The survey also found that doctors were interested in using AI tools for early detection and personalised treatment plans to manage diabetes




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Synthesis and evaluation of photoaffinity labeling reagents for identifying binding sites of sulfated neurosteroids on NMDA and GABAA receptors

RSC Adv., 2024, 14,36352-36369
DOI: 10.1039/D4RA07074G, Paper
Open Access
  This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.
Mingxing Qian, Yuanjian Xu, Hong-Jin Shu, Zi-Wei Chen, Lei Wang, Charles F. Zorumski, Alex S. Evers, Steven Mennerick, Douglas F. Covey
Photoaffinity labels (PALs) for sulfated steroid binding sites on GABAA and NMDA receptors. The PALs have varying profiles of positive and negative modulatory (PAM and NAM) actions.
The content of this RSS Feed (c) The Royal Society of Chemistry




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Satish Jarkiholi supporter to lead Belagavi DCC bank

Before the election, the three Jarkiholi brothers — Satish (Congress MLA), Ramesh (BJP MLA), and Balachandra (BJP MLA) — met in a private hotel in Belagavi to discuss the names of candidates




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PUCL condemns opposition to Dalits’ entry into temple in Mandya village




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FIR registered against Snehamayi Krishna




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Kalaburagi city police arrests 30 vehicle lifters, recovers 105 motorbikes




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Three youths go missing after coracle overturns in Sharavathi backwaters in Sagar taluk




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Comeback man Shami hogs the spotlight as MP takes honours on opening day against Bengal




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Ennoventure bags $8.9 million in Series A led by Tanglin Venture Partners

The round included participation from existing investors, such as Fenice Investment Group and additional SAFE investors




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Tilak’s maiden ton, Abhishek’s 50 fire India to 219/6 against South Africa in 3rd T20I

Tilak Varma got ample backing from Abhishek Sharma who made a brisk 50 after SA skipper Aiden Markram invited the visitors to bat first.




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A hundred years ago | Wilts’ centenary




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Fifty years ago | Tamil Nadu omnibus tax increase held valid




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Pro Kabaddi League: Gujarat Giants return to winning ways with big win over Bengal Warriorz

In the second match of the night, Haryana Steelers moved to the top of the table and extended their winning run to four games after defeating the Patna Pirates 37-32




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Villagers oppose proposal for quarry near Sathanur dam at a public hearing

Tiruvannamalai Collector D. Bhaskara Pandian chaired the hearing organised by the TNPCB on Wednesday. The black granite quarry is proposed to be set up on about 8.46 hectares of government land in Sathanur




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Nagamohan Das to head panel to suggest internal reservation among SC communities




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Village Administrative Officer arrested in DVAC trap in Tiruppur




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Tambaram Corporation begins population survey and area mapping for improved coverage of UPHCs




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No roadmap yet for better traffic signage system in Kozhikode city

Emergency signboards and lane markings near roundabouts have not yet been introduced to streamline the traffic management




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FIR against Hinduvta activist Puneeth Kerehalli




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Co-Founder of The Banyan bags Sat Paul Mittal National Award




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ED files Prosecution Complaint against Jaffer Sadiq before Additional CBI Court

A release said 20 persons had been arraigned as accused in the case, and Jaffer Sadiq was identified as the mastermind




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After Uddhav Thackeray calls EC biased for checking his bags, Eknath Shinde releases videos of his bags being checked

Eknath Shinde’s luggage was being checked at the Palghar police ground helipad as part of Standard Operating Procedures (SOPs)




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Engineering seat blocking scam: FIR booked against IP addresses




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In Beed, Independent candidates on strong footing against party nominees

Candidates who rebelled against party diktat stand out with strong support at the ground level and also have high chances of winning the seat




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Action initiated against apartment for connecting sanitary line to Cauvery pipeline




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Playgrounds in Bengaluru: A mixed bag for parents and children




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Defence Space Agency conducts maiden tabletop exercise ‘Antariksha Abhyas’

One of the aims of the exercise was also to identify vulnerabilities in conduct of operations in the event of denial or disruptions of space-based services




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Waltair Divisional Railway Manager inspects Koraput-Jagdalpur section




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Jana Sena Party corporator alleges neglect of crematorium facelift, stages protest




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HC directs authorities to return Bharat Mata statue removed from BJP office in Virudhunagar

The State told the court that a Division Bench had directed the authorities to ensure that no person or party was permitted to install statues in the State without getting proper permission




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Prioritising mental wellbeing can help in management of diabetes, say doctors




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Food and beverages inflation surged to 9.7% in October, Dec, rate cut unlikely: ICRA’s Nayar

Food and beverage inflation for October compares with 8.4% in September, led by an increase in seven of the 12 food groups. Vegetables inflation reached a 57-month high of 42.2% from 36.0% in September, exerting upward pressure on the overall CPI.”




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Piccadily Agro Industries announces ₹1,000 crore expansion; to set up new distilleries in India and Scotland

The expansions are expected to be completed over the next 24 months




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Will markets hop on the AI bandwagon?

Machine learning and AI usage are already entrenched in capital markets. But adoption of advanced AI/GenAI tools will be slow




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Rupee falls 1 paisa to all-time low of 84.40 against US dollar in early trade

Meanwhile, the dollar index was trading lower by 0.04 per cent at 105.98




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Mid-day updates: Markets deepen losses as metals, auto stocks drag; Sensex down nearly 500 points 

The broader market reflected selling pressure, particularly in metal and automotive sectors, with Hindalco leading the decline at 3.67 per cent




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Rupee rises 1 paisa to close at 84.38 against US dollar

Rupee weighed down by foreign fund outflows, domestic equities




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Gold prices tumble as dollar strengthens against rupee

Global uncertainty, weak domestic economy pushing gold, rupee and equity



  • Gold & Silver

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On ‘bulldozer justice’ Supreme Court sends a message. Will it be heard?




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November 14, 1984, Forty Years Ago: Election Dates Out




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Should You Invest In Arbitrage Funds?

'Arbitrage funds make the most sense for those in the 30 per cent tax bracket, are viable for those in the 20 per cent bracket, but less so for those in the 10 per cent bracket.'




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Coming Soon! World Pickleball League

'The league will begin as a city-based franchise setup, starting with six cities.'




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Rule of law citizens' umbrella against State's power: SC

It said the law must be just and fair and should protect the human rights and dignity of all members of society.




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SA vs IND: Tilak Varma scripts history with maiden century in 3rd T20I against South Africa

Despite the early dismissals of Suryakumar Yadav, Hardik Pandya, and Rinku Singh, Tilak continued his onslaught and ensured India posted a formidable total of 219 runs on the board.