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Data-based methods for materials design and discovery: basic ideas and general methods / Ghanshyam Pilania, Prasanna V. Balachandran, James E. Gubernatis, Turab Lookman

Online Resource




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Promote all school students next year or use internal assessment mechanism: Kapil Sibal

With uncertainty looming over the 2020-2021 academic session of schools in the wake of the Covid-19 pandemic, former Human Resource Development Mini




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Covid-19: Karnataka sees biggest single-day jump of 54

With 54 new cases, Karnataka witnessed the highest single-day jump in number of new positive cases. The largest number of patients tested positive to




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ICICI Bank: Investors should wait for a turnaround in credit demand

ICICI Bank stock has corrected 37 per cent in three months. But investors should not rush into it




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‘Paul Pogba, Bruno Fernandes can thrive in United midfield’: Ole Gunnar Solskjaer




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EPA public meeting on October 24 to discuss cleanup at Vernay Laboratories site in Yellow Springs, Ohio

YELLOW SPRINGS, Ohio (October 17, 2019) – The U.S. Environmental Protection Agency (EPA) will present the proposed cleanup options for the Vernay Laboratories Inc. site at a public meeting on Thursday, Oct. 24 in Yellow Springs. The information session will run from 5-7 p.m.




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Photos: Purdue takes on Michigan St. in Big Ten women's tournament

Photos: Purdue takes on Michigan St. in Big Ten women's tournament

      




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Photos: Maryland defeats Purdue women in Big Ten tournament

Photos: Maryland defeats Purdue women in Big Ten tournament

      




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Angola as a Global Influence: Priorities for International Cooperation

Research Event

13 June 2014 - 3:30pm to 4:30pm

Chatham House, London

Event participants

Dr Maria Ângela Bragança, Secretary of State for Cooperation, Ministry of External Relations, Angola

Reaping the benefits of more than a decade of stability and fast economic growth, Angola increasingly wields global influence. Angola seeks to diversify its bilateral partnerships and improve existing ones, and is well-placed to exert its influence in multilateral fora. 

At this roundtable event, Angola’s Secretary of State for Cooperation, Hon Dr Maria Angela Bragança, will discuss Angola’s international priorities and how Angola is helping to shape key issues of global importance in a multipolar world.

Department/project

Christopher Vandome

Research Fellow, Africa Programme
+44 (0) 20 7314 3669




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China and the Future of Global Governance

Research Event

29 January 2015 - 1:00pm to 2:00pm

Chatham House, London

Event participants

Dr Katherine Morton, Senior Fellow, Department of International Relations, Australian National University
Chair: Professor Shaun Breslin, Associate Fellow, Asia Programme, Chatham House

How is China’s growing international status likely to affect the future trajectory of global governance? Will it operate within the confines of liberal order, or attempt to substantively revise the existing global framework? The speaker will argue that China is now playing an active role in shaping the rules, norms, and institutions of global governance. She will offer some fresh insights into this new trend in Chinese foreign policy by placing a lens upon key global policy-making realms, including the maritime commons, where conflicts over international norms and national interests are most stark.

THIS EVENT IS NOW FULL AND REGISTRATION IS CLOSED.

Department/project

Joshua Webb

+44 (0)20 7314 3678




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NF-{kappa}B mediates lipopolysaccharide-induced alternative pre-mRNA splicing of MyD88 in mouse macrophages [Signal Transduction]

Although a robust inflammatory response is needed to combat infection, this response must ultimately be terminated to prevent chronic inflammation. One mechanism that terminates inflammatory signaling is the production of alternative mRNA splice forms in the Toll-like receptor (TLR) signaling pathway. Whereas most genes in the TLR pathway encode positive mediators of inflammatory signaling, several, including that encoding the MyD88 signaling adaptor, also produce alternative spliced mRNA isoforms that encode dominant-negative inhibitors of the response. Production of these negatively acting alternatively spliced isoforms is induced by stimulation with the TLR4 agonist lipopolysaccharide (LPS); thus, this alternative pre-mRNA splicing represents a negative feedback loop that terminates TLR signaling and prevents chronic inflammation. In the current study, we investigated the mechanisms regulating the LPS-induced alternative pre-mRNA splicing of the MyD88 transcript in murine macrophages. We found that 1) the induction of the alternatively spliced MyD88 form is due to alternative pre-mRNA splicing and not caused by another RNA regulatory mechanism, 2) MyD88 splicing is regulated by both the MyD88- and TRIF-dependent arms of the TLR signaling pathway, 3) MyD88 splicing is regulated by the NF-κB transcription factor, and 4) NF-κB likely regulates MyD88 alternative pre-mRNA splicing per se rather than regulating splicing indirectly by altering MyD88 transcription. We conclude that alternative splicing of MyD88 may provide a sensitive mechanism that ensures robust termination of inflammation for tissue repair and restoration of normal tissue homeostasis once an infection is controlled.




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Opportunities for Transatlantic Cooperation on International Migration

The EU-U.S. relationship is one of the most significant partnerships among wealthy nations. Interconnections between the two on migration issues make dialogue necessary and inevitable, as each relies on each other to attain a number of policy objectives, most clearly in the case of travel and border security.




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RNA interference machinery influences epithelial cell biology

Epithelial cells are held together and connected by several different types of structures that form cell-cell contacts.




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Filmfare recommends: Bollywood films revolving around journalism – Filmfare

Filmfare recommends: Bollywood films revolving around journalism  Filmfare



  • IMC News Feed

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Incarnate School of Art and Mission 2014 begins

For the second time, OM Italy hosts the Incarnate School of Art and Mission in Bobbio Pellice.




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Benvenuto a Incarnate

OM Arts introduces locals from Isola, Italy to Incarnate - a programme teaching artists to work in cross-cultural missions.




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International arts festival impacts Italian community

Artists present visual and performing arts during the international art Festival Week hosted by OM Arts International’s Incarnate programme.




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Incarnate 2016

Artists gathered in Italy for Incarnate 2016 with purpose: to pursue the arts while engaging in cross-cultural missions. 




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Panini Pandya selected as international politics marshal

As part of Penn State’s 2020 spring commencement activities, Panini Pandya will represent international studies as its student marshal. Pandya, a Paterno Fellow and Schreyer Scholar, will graduate with bachelor of arts degrees in international politics, Spanish and history, with a minor in geography.




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MIDDLEFORD RD FROM OLD FURNACE RD TO RT 13 HAS A EB LANE CLOSURE DUE TO CONSTRUCTION UNTIL 6PM




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RT 1 SB IS CLOSED BEFORE THE RAMPS TO RT 13 NB AND RAMP TO RT 71, PLEASE USE AN ALTERNATE ROUTE




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Aprilia RS660 Supersport spotted testing undisguised: A worthy Daytona alternative?

Aprilia RS660 will soon be making an official entry to the markets soon and the latest spy shot reveals a lot of interesting details.




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Sebi asks 8 entities to make open offer to Kanchan International shareholders

The market regulator also directed the entities to pay 10 per cent interest along with the offer price to shareholders who were holding shares at the time when the company violated the Sebi norms.




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Covid-19 pandemic: Growth lessons for states from Gujarat, Karnataka

The pandemic and its economic consequences have given every state economy the unprecedented opportunity to take bold decisions and accelerate decadal growth.




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how to change surname

I want to change the surname,but my wife and children have old surname,how to change their surname also





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Unpublished Iraq War Logs Trigger Internal WikiLeaks Revolt





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Leaked Internal Presentation Details the Oil Industry's Campaign to Stop Clean Energy

The Western States Petroleum Association (WSPA) — whose members include Chevron, ExxonMobil, Shell, ConocoPhillips, BP, and others — was caught red-handed late last month when a leaked internal presentation revealed a coordinated campaign to stomp out climate and clean energy progress in California, Oregon and Washington by propping up over 15 front groups that purport to represent the views of concerned citizens and the broader business community.




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India Renewables Boom Aided by International Funds

India said cheaper credit along with foreign investment will help the world’s third-largest polluter fund an ambitious renewable energy program that would build green power plants faster than China.




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What Drives Alternative Energy Stocks?

Alternative energy became a serious market player after the turn of the millennium. Since that time, solar, wind, smart grid and other alternative energy stocks have experienced both strong up and down trends. The forces at work driving these markets are complex, counterintuitive, and sometimes mysterious. This article looks at what has been driving the price of alternative energy markets, and as a result, alternative energy company stocks.




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Alternative Energy Outperforms All Other Sectors in September

Alternative energy mutual funds (MF) racked up extremely robust gains in the past year. Returns range from a low of 16 percent, to a high of 64 percent for a mutual fund that is heavy into solar investments. Exchange traded funds (ETF) also did well, but returns are much more variable. They range from a loss of 34 percent for a carbon ETF, to more than doubling of a solar ETF.




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International Geothermal Industry Developing Strong Partnerships, Robust Market

This year’s Geothermal Energy Association (GEA)’s Geothermal Energy Expo and Geothermal Resources Council’s Annual Meeting incorporated a wide range of meetings on international development. U.S. interest in exporting geothermal goods and services is ever-increasingly met with outside interest in U.S. knowledge and materials, particularly from developing countries.




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International Geothermal Market Set for Development Boom but Challenges Remain

What’s the next big opportunity for geothermal? According to panelists at last week's Renewable Energy World North America international geothermal session, it’s emerging markets. Kicking off the two-hour discussion, special guest Agnes Dasewicz of the U.S. Agency for International Development (USAID) explained the Power Africa initiative, which launched in June 2013. USAID is attempting to unlock energy growth in six countries: Kenya, Tanzania, Ghana, Nigeria, Liberia, and — of particular interest to the geothermal crowd — Ethiopia.




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India Renewables Boom Aided by International Funds

India said cheaper credit along with foreign investment will help the world’s third-largest polluter fund an ambitious renewable energy program that would build green power plants faster than China.




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Israeli settlements require international legal attention, envoy says

A U.N. special envoy on Palestinian issues said Friday it was time for the International Court of Justice to assess what he said was Israeli colonialism.




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Income Strip, Annuity, Bond – alternative investment in real estate

Eversheds Sutherland property column: September 2018 Originally published in Practical law In these uncertain times, if cash is king, income is emperor. As a consequence, investors are looking for long-term, lower risk investments in the real estate...




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Income Strips and Student Accommodation - an alternative funding model for Higher Education Institutions

Economic and political uncertainty since the Brexit vote and fear of a predicted debt crisis have increased funding pressures on Higher Education Institutions when putting their estates strategies into action.  A perfect storm of a predicted dr...




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Accessing foreign investment protection for international construction and engineering projects

In 2015, the United Nations Conference on Trade and Development (UNCTAD) estimated that foreign direct investment for the construction of greenfield projects in developing economies had jumped from US$22 billion in 2013, to US$42 billion in 2014 wit...




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Nigerian journalist, medical workers test positive for coronavirus

A journalist working in Bauchi State has tested positive for coronavirus. The Bauchi State Task Force on COVID-19 made the announcement at a briefing on Saturday. NAN reports that the Deputy Governor, Baba Tela, did not disclose the identity of the journalist. He advised all newsmen in the state to go check their COVID-19 status. […]

Nigerian journalist, medical workers test positive for coronavirus




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Fiverr International Ltd. (FVRR) CEO Micha Kaufman on Q1 2020 Results - Earnings Call Transcript




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Oncternal Therapeutics, Inc. (ONCT) CEO Dr. Jim Breitmeyer on Q1 2020 Results - Earnings Call Transcript




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Nigeria: Fortify and the Wellbeing Foundation Africa Announce Strategic Partnership to Reduce Iron Deficiency and Improve Maternal Survival in West Africa

[Wellbeing Foundation] CHICAGO, Illinois and LAGOS, NIGERIA -Partnership combines private sector ingenuity with local know-how and leadership to save the lives of millions of women and children suffering from iron deficiency




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Golf tournament to use high-tech ID chip badges to track spectators


The sale of draft beer and fountain drinks will be prohibited while all transactions will be restricted to credit cards.





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Salman Khan, Jacqueline Fernandez's 'Tere Bina' teaser is out now

Salman Khan also extended wishes to all the mothers on Mother’s Day.




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ANP to not commemorate May 12 carnage this year

The Awami National Party Sindh chapter has decided not to hold a gathering to commemorate the May 12 carnage because of the coronavirus outbreak.ANP Sindh president Shahi Syed said that the May 12, 2007, tragedy was unforgettable for them and the party would continue to commemorate it until those...




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Centre Allots 2.1 Lakh Tonnes Free Food Grain to Karnataka Under PM Garib Kalyan Yojana Package

The Central government will bear the total cost of Rs 2,351 crore for supplying the free food grains to beneficiaries in Karnataka for the three months.





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Centre Allots 2.1 Lakh Tonnes Free Food Grain to Karnataka Under PM Garib Kalyan Yojana Package

The Central government will bear the total cost of Rs 2,351 crore for supplying the free food grains to beneficiaries in Karnataka for the three months.





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Andy Serkis says 'The Batman' is going to be the darkest incarnation yet

Andy Serkis says the upcoming Batman film will be darker and broodier than the previous cinematic incarnations.