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Lactobionic acid modified cobalt coordination polymer-coated peroxymonosulfate nanoparticles generate sulfate/hydroxy dual-radicals for targeted cancer therapy

J. Mater. Chem. B, 2024, Advance Article
DOI: 10.1039/D4TB01777C, Paper
Jiahui Li, Jiaxuan Li, Zelong Chen, Yichen Wan, Yi Wang, Zhichao Pei, Yuxin Pei
LCP NPs were prepared by forming a coordination polymer on peroxymonosulfate through the coordination between imidazole-2-carboxaldehyde and Co2+, then modified with lactobionic acid to improve the efficacy of sulfate/hydroxy dual-radical therapy.
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Development of a Xanthene-Based NIR Fluorescent Probe for Accurate and Sensitive Detection of γ-Glutamyl Transpeptidase in Cancer Diagnosis and Treatment

J. Mater. Chem. B, 2024, Accepted Manuscript
DOI: 10.1039/D4TB01841A, Paper
Chia-Kai Lai, KUPPAN MAGESH, Sivan Velmathi, Shu-Pao Wu
γ-Glutamyl transpeptidase (GGT) regulates glutathione (GSH), essential for cell functions and linked to cancer. High GGT levels in tumors make it a valuable cancer biomarker. Current GGT detection methods often...
The content of this RSS Feed (c) The Royal Society of Chemistry




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Quantum DFT analysis and molecular docking investigation of various potential breast cancer drugs

J. Mater. Chem. B, 2024, Accepted Manuscript
DOI: 10.1039/D4TB01803F, Paper
Ashraf Ayub, Ankit Raj Tyagi, Sunil Kumar Srivastava, Pranveer Singh
Breast cancer is the most often diagnosed and deadliest type of cancer in the world. These days, the world is facing the threat of breast cancer. It is essential to...
The content of this RSS Feed (c) The Royal Society of Chemistry




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Cuproptosis in cancer therapy: mechanisms, therapeutic application and future prospects

J. Mater. Chem. B, 2024, Advance Article
DOI: 10.1039/D4TB01877J, Review Article
Jiawei Hu, Junfei Zhu, Tao Chen, Yudie Zhao, Qingwen Xu, Yan Wang
Cuproptosis is a regulated form of cell death induced by the accumulation of metal ions and is closely linked to aspects of cellular drug resistance, cellular metabolism, and signalling pathways.
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Advancing cancer therapy with a heptamethine carbocyanine dye-conjugated radionuclide drug

J. Mater. Chem. B, 2024, Advance Article
DOI: 10.1039/D4TB01798F, Paper
Mingxing Huang, Weichen Wang, Yingwei Wang, Rang Wang, Lili Pan, Xin Li, Bo Li, Jingsong Zhang, Ruoxiang Wang, Yi Zhang, Rong Tian
Malignant tumors pose substantial treatment challenges due to their heterogeneity, metastatic potential, and therapeutic resistance, underscoring the urgent need for more effective treatment options.
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Illuminating cisplatin-induced ferroptosis in non-small-cell lung cancer with biothiol-activatable fluorescent/photoacoustic bimodal probes

J. Mater. Chem. B, 2024, Advance Article
DOI: 10.1039/D4TB01656D, Paper
Li Xu, Hongwen Liu, Yi Kong, Lingyun Li, Jia Li, Kang Li, Shuzhi Liang, Bolin Chen
Using activatable NIR fluorescent/PA bimodal probes, we successfully monitored real-time biothiol changes during ferroptosis in NSCLC cells and tumors, revealing enhanced ferroptosis with the combined use of erastin and cisplatin.
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can

Bigg Boss 11: 'I can't believe I am evicted!'

'Arshi never crossed her boundary.''Initially, Akash was entertaining but slowly, he's become irritating because he changes groups without being loyal to anyone.' Hiten Tejwani discusses the contestants on Bigg Boss 11, and reserves the worst for Hina Khan.





can

'We can't say TV is regressive'

'The content on television is directly proportional to what the audience likes.'




can

'Can you imagine dancing with Madhuri Dixit?'

Madhuri Dixit, Karan Johar and Nora Fatehi will judge Jhalak Dikhhla Jaa.




can

Can Ankit Gupta Win Bigg Boss 16?

'Even if I last in the house for a few weeks/months, it would be great as I am somebody who doesn't like to be with too many people. If I achieve that, it will be a trophy for me.'





can

Bigg Boss 10's Sapna Choudhary At Cannes

'It's been a long journey full of sweat, sacrifice, and determination, but it's all worth it.'




can

'You can't prepare to jump off a building'

'We are getting a show to do stuff like jumping off a helicopter.''Even if you pay, you won't get to do these things.'




can

‘You go to meet the prime minister and all you can talk about is my bluddy swimming pool?’

When prime minister Rajiv Gandhi was lectured on free market economics, and cornered about the luxury addition in Satish Sharma’s farmhouse






can

What's Elvis Doing In Cannes?

Baz Luhrmann's new film Elvis got a 10-minute standing ovation at the Cannes film festival.




can

Alterations of the chemical profile of cholesterol in cancer tissue as traced with ToF-SIMS

Analyst, 2024, 149,5344-5352
DOI: 10.1039/D4AN01050G, Paper
Open Access
  This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.
Auraya Manaprasertsak, Julhash U. Kazi, Catharina Hagerling, Kenneth J. Pienta, Per Malmberg, Emma U. Hammarlund
This study uses Time-of-Flight Secondary Ion Mass Spectrometry (ToF-SIMS) to analyze cholesterol alterations in cancer tissue, revealing changes in fragmentation and isotopes that suggest potential diagnostic vulnerabilities.
The content of this RSS Feed (c) The Royal Society of Chemistry




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Effects of media composition and light exposure on the electrochemical current response during scanning electrochemical microscopy live cell imaging

Analyst, 2024, 149,5555-5562
DOI: 10.1039/D4AN01075B, Paper
Nikita Thomas, Mengzhen Lyu, Jadon Khouv, Dhésmon Lima, Sabine Kuss
The cellular electrochemical current response is impacted by media composition and light exposure during scanning electrochemical microscopy (SECM).
The content of this RSS Feed (c) The Royal Society of Chemistry




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An improved cancer diagnosis algorithm for protein mass spectrometry based on PCA and a one-dimensional neural network combining ResNet and SENet

Analyst, 2024, Advance Article
DOI: 10.1039/D4AN00784K, Paper
Liang Ma, Wenqing Gao, Xiangyang Hu, Dongdong Zhou, Chenlu Wang, Jiancheng Yu, Keqi Tang
An improved cancer diagnosis algorithm for protein mass spectrometry based on PCA and 1D neural network combining ResNet and SENet is proposed and successfully applied to the diagnosis of ovarian cancer with high accuracy and strong fitting ability.
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Banks of Canara



  • A J Vinayak

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Two-dimensional Janus XWZAZ' (X = S, Se, Te; A = Si, Ge; Z, Z' = N, P, As): candidates for photocatalytic water splitting and piezoelectric materials

Phys. Chem. Chem. Phys., 2024, 26,27314-27324
DOI: 10.1039/D4CP03503H, Paper
Zhen Gao, Hongbo Wu, Yao He, Kai Xiong
Janus two-dimensional (2D) materials exhibit strong light absorption and high solar-to-hydrogen conversion efficiency, making them promising candidates for photocatalytic water splitting applications.
The content of this RSS Feed (c) The Royal Society of Chemistry




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Effects of surface oxygen vacancy on CO2 adsorption and its activation towards C2H4 using metal (Cu, Pd, CuPd) cluster-loaded TiO2 catalysts: A first principles study

Phys. Chem. Chem. Phys., 2024, Accepted Manuscript
DOI: 10.1039/D4CP03507K, Paper
Sajjad Hussain, Lina Zhang, Zhengzheng Xie, Jianjun Yang, Qiuye Li
The conversion of the highly selective CO2 reduction reaction (CO2RR) into desired value-added multicarbon compounds, like C2H4, is crucial, but it is mainly constrained by high energy barrier for C-C...
The content of this RSS Feed (c) The Royal Society of Chemistry




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Mechanistic Insights into CO2 Activation on Pristine, Vacancy-containing and Doped Goldene: A Single-Atom Layer of Gold

Phys. Chem. Chem. Phys., 2024, Accepted Manuscript
DOI: 10.1039/D4CP03087G, Paper
Kamal Kumar, Nora Henriette De Leeuw, Jost Adam, Abhishek Kumar Mishra
Goldene, a one-atom-thick gold sheet, is an emerging graphene-like flat 2-dimensional material. In this study, the geometrical and electronic properties, as well as CO2 adsorption characteristics, of the pristine,...
The content of this RSS Feed (c) The Royal Society of Chemistry




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Intermolecular Hydrogen Bonding Delineates Stability of Non-canonical Adenine Base Pairs: A First-Principles Study

Phys. Chem. Chem. Phys., 2024, Accepted Manuscript
DOI: 10.1039/D4CP02875A, Paper
Nicholas Adu-Effah, Nabanita Saikia
Non-canonical nucleobase pairs differ from canonical Watson-Crick (WC) pairs in their hydrogen bonding patterns. This study uses density functional theory with empirical dispersion correction to examine the stability and electronic...
The content of this RSS Feed (c) The Royal Society of Chemistry




can

Oxygen vacancy chemistry in oxide cathodes

Chem. Soc. Rev., 2024, 53,3302-3326
DOI: 10.1039/D3CS00872J, Review Article
Yu-Han Zhang, Shu Zhang, Naifang Hu, Yuehui Liu, Jun Ma, Pengxian Han, Zhiwei Hu, Xiaogang Wang, Guanglei Cui
This review focuses on the chemical thermodynamics and reaction kinetics of intrinsic and anionic redox-mediated oxygen vacancies in oxide cathodes.
The content of this RSS Feed (c) The Royal Society of Chemistry




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Advancing nanotechnology for neoantigen-based cancer theranostics

Chem. Soc. Rev., 2024, 53,3224-3252
DOI: 10.1039/D3CS00162H, Tutorial Review
Open Access
  This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.
Jianhua Zou, Yu Zhang, Yuanbo Pan, Zhengwei Mao, Xiaoyuan Chen
Developing nanotechnology for neoantigen-based precision therapy, including photodynamic therapy, photothermal therapy, radiotherapy, chemo/chemodynamic therapy, immunotherapy, and other therapies.
The content of this RSS Feed (c) The Royal Society of Chemistry




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SERS in 3D cell models: a powerful tool in cancer research

Chem. Soc. Rev., 2024, Advance Article
DOI: 10.1039/D3CS01049J, Review Article
Open Access
Lara Troncoso-Afonso, Gail A. Vinnacombe-Willson, Clara García-Astrain, Luis M. Liz-Márzan
3D cancer models recapitulate the tumor microenvironment and serve as a platform to study cancer cell behavior, drug discovery and early diagnosis, which can be monitored chemically with subcellular resolution in real time, via SERS.
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Peptide-based self-assembled monolayers (SAMs): what peptides can do for SAMs and vice versa

Chem. Soc. Rev., 2024, 53,3714-3773
DOI: 10.1039/D3CS00921A, Review Article
Open Access
  This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.
Carlos Redondo-Gómez, Paula Parreira, M. Cristina L. Martins, Helena S. Azevedo
Self-assembled monolayers (SAMs) based on peptides represent a reproducible platform for screening and studying peptide functions and facilitating their translation into multidisciplinary applications.
The content of this RSS Feed (c) The Royal Society of Chemistry




can

Max Verstappen wins 3rd straight Canadian Grand Prix for 60th Formula 1 victory

Verstappen finished more than three seconds ahead of McLaren's Lando Norris in the 70-lap race




can

Can Lando Norris whiz past Max Verstappen in an ever-tightening F1 title race?

The drivers’ championship appeared a foregone conclusion at one stage this season, but Norris and McLaren have changed the complexion of the title picture. While Verstappen still enjoys a 52-point lead, Norris is the in-form driver — the final run of races could well be the making of him




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Men’s hockey: Sreejesh’s saves were nothing short of miracle, we can win gold at Paris Olympics, says Dhanraj Pillay

As soon as Rajkumar Pal scored the winning goal in the shoot-off, an emotional Dhanraj, glued to the TV at home, jumped in joy.




can

RTE seats lie vacant in districts

Ramanathapuram tops southern districts in enrolment




can

Ban the use of cane in classroom




can

A girl can build anything / written by e.E. Charlton-Trujillo and Pat Zietlow Miller ; illustrated by Keisha Morris

Charlton-Trujillo, e. E., author




can

How to spacewalk : step-by-step with shuttle astronauts / created by Kathryn D. Sullivan, the first American woman to walk in space, and Michael J. Rosen ; illustrated with images from NASA and drawings by Michael J. Rosen

Sullivan, Kathy, 1951- author




can

Light : energy we can see! / Julie K. Lundgren

Lundgren, Julie K., author




can

Restoring prairie, woods, and pond : how a small trail can make a big difference / Laurie Lawlor

Lawlor, Laurie, author




can

Volcanoes / written by Nell Cross Beckerman ; illustrated by Kalen Chock

Beckerman, Nell Cross, 1973- author




can

The Journey Prize : stories : the best of Canada's new writers / selected by Kevin Hardcastle, Grace O'Connell, Ayelet Tsabari




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Can you hear the plants speak? / Nicholas Hummingbird with Julia Wasson ; illustrations by Madelyn Goodnight

Hummingbird, Nicholas, author




can

Canada wild : animals found nowhere else on Earth / words by Maria Birmingham ; art by Alex MacAskill

Birmingham, Maria, author




can

Extreme weather for kids : lessons and activities all about hurricanes, tornadoes, blizzards, and more! / Matthew Cappucci ; illustrated by Stephanie Hathaway

Cappucci, Matthew, author




can

This facial scan can unlock health secrets 

Startup deploys machine learning on a mobile app to pinpoint potential disease risks




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Engineering biotin anchored-MWCNTs as a superb carrier for facile delivery of the potent Ru(II)-N^N scaffold in breast cancer cells

Chem. Commun., 2024, 60,13376-13379
DOI: 10.1039/D4CC04276J, Communication
Lavanya Thilak Babu, Nilmadhab Roy, Tiasha Dasgupta, Sreejani Ghosh, Ramasamy Tamizhselvi, Priyankar Paira
This article portrays the construction of biotinylated-MWCNTs for SMVT-guided delivery of a potent Ru(II)-scaffold into MCF7 cells.
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When Kashmiri kehwa sells out in Canada

Niche regional spices and foods are seeing a surge in popularity, both within India and abroad, in a movement spearheaded by a homesick diaspora, curious lockdown cooks and innovative entrepreneurs



  • Life & Style

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Farmlore in Bengaluru sets out to prove that luxury dining can be local, ethical and even fun

Set on 37 acres of farmland, the restaurant seats just 18 guests, serving multi-course menus starring ethically sourced seafood and meat, as well as freshly harvested vegetables and foraged wild greens




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Development of xanthan gum-based solid desiccants for the extraction of water vapors from humid air

Mol. Syst. Des. Eng., 2024, Advance Article
DOI: 10.1039/D4ME00134F, Paper
Hemant Mittal, Ali Al Alili, Saeed M. Alhassan, Naved I. Malek, Md. Didarul Islam
A xanthan gum-acrylamide desiccant with interconnected capillary channels was prepared and showed 1.38 g g−1 water adsorption at 90% RH and 25 °C, retaining 70% capacity over 20 cycles, proving its effectiveness as a salt-free desiccant.
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