si How Coca-Cola shaped obesity science and policy in China By feeds.bmj.com Published On :: Wed, 09 Jan 2019 17:25:25 +0000 Susan Greenhalg is a research professor of chinese society in Harvard’s department of anthropology - not a natural fit for a medical journal you may think, but recently she has been looking at the influence of Coca Cola on obesity policy in China. She has written up her investigation in an article published on bmj.com this week, and joins us in... Full Article
si Assisted dying: should doctors help patients to die? By feeds.bmj.com Published On :: Mon, 04 Feb 2019 15:28:01 +0000 The Royal College of Physicians will survey all its members in February on this most controversial question. It says that it will move from opposition to neutrality on assisted dying unless 60% vote otherwise. The BMJ explores several conflicting views. From Canada, palliative care doctor Sandy Buchman explains why he sees medical aid in dying... Full Article
si Chronic Rhinosinusitis By feeds.bmj.com Published On :: Fri, 08 Feb 2019 13:58:35 +0000 Patients who experience chronic rhinosinusitis may way for a considerable period of time before presenting, because they believe the condition to be trivial. In this podcast, Alam Hannan, ENT Consultant at the Royal Throat Nose and Ear Hospital in London, explains why that belief is not founded, and describes which treatments can be effective at... Full Article
si Diabetes Insipidus - the danger of misunderstanding diabetes By feeds.bmj.com Published On :: Fri, 01 Mar 2019 18:10:43 +0000 Diabetes is synonymous with sugar, but diabetes insipidus, "water diabetes", can't be forgotten. Between 2009 and 2016, 4 people died in hospital in England, when lifesaving treatment for the condition was not given. In this podcast, we hear some practical tips for non-specialists to aid diagnosis, and how patients should be managed during... Full Article
si Signals from the NIHR By feeds.bmj.com Published On :: Thu, 07 Mar 2019 18:02:07 +0000 If you've been keeping up to day with The BMJ - online on in print, you might have noticed that we've got a new type of article - NIHR Signals - and they are here to give busy clinicians a quick overview of practice changing research that has come out of the UK's National Institute for Health Research. Tara Lamont, director of the NIHR... Full Article
si Ebola - Stepping up in Sierre Leone By feeds.bmj.com Published On :: Fri, 08 Mar 2019 16:36:33 +0000 In 2014, Oliver Johnson was a 28 year old British doctor, working on health policy in Sierre Leone after finishing medical school. Also working in Freetown was Sinead Walsh, then the Irish Ambassador to the country. Then the biggest outbreak of Ebola on record happened in West Africa, starting in Guinea and quickly spreading to Liberia, Sierre... Full Article
si Passing on the secret knowledge of loop diuretics By feeds.bmj.com Published On :: Fri, 15 Mar 2019 17:07:15 +0000 In every generation there are a few that know the secret; the counterintuitive effects of loop diuretics. In this podcast Steven Anisman, cardiologist at the Dartmouth Hitchcock Department of Cardiovascular Medicine, joins us to explain about the threshold effects of these drugs, and why that might change the way in which you think about... Full Article
si Capital punishment, my sixth great grandfather, and me By feeds.bmj.com Published On :: Tue, 09 Apr 2019 16:49:48 +0000 On the 7th of June, 1753, Dr Archibald Cameron was executed at Tyburn. "The body, after hanging twenty minutes, was cut down: it was not quartered; but the heart was taken out and burnt. " 250 years later, his sixth great grandson, Robert Syned found himself deeply involved in the process of execution, as an expert witness in a case about the use... Full Article
si Talk evidence - cancer causing food, prostate cancer and disease definitions By feeds.bmj.com Published On :: Sat, 25 May 2019 12:11:43 +0000 Helen Macdonald and Carl Heneghan are back again talking about what's happened in the world of evidence this month. (1.05) Carl rants about bacon causing cancer (7.10) Helen talks about prostate cancer, and we hear from the author of the research paper which won Research Paper Of The Year at the BMJ awards. We also cover disease definition and... Full Article
si Cannabinoid Hyperemesis Syndrome By feeds.bmj.com Published On :: Fri, 19 Jul 2019 15:47:49 +0000 Cannabinoid hyperemesis syndrome is a relatively newly recognised condition - but, according to one study, can account for up to 6% of patients presenting to emergency departments. The causal mechanism is as yet unclear - but currently the only known way to prevent the syndrome is for the patient to stop their cannabis use. Yaniv Chocron, chief... Full Article
si Burnout - Don't try to make the canary in the coal mine more resilient By feeds.bmj.com Published On :: Thu, 08 Aug 2019 16:59:04 +0000 Burnout is a problem in healthcare - it’s a problem for individuals, those who experience it and decide to leave a career they formerly loved, but it’s also a problem for our healthcare system. Burnout is associated with an increase in medical errors, and poor quality of care. Fundamentally it’s a patient safety issue. But, unlike other patient... Full Article
si Physical activity and mortality - "The least active quartile did less than 5 minute per day" By feeds.bmj.com Published On :: Fri, 23 Aug 2019 14:29:32 +0000 We know that exercise is good for you - the WHO recommends at least 150 minutes of moderate intensity or 75 minutes of vigorous intensity aerobic physical activity each week. That recommendation is built on evidence that relied on self reporting that may underestimate the amount of lower intensity exercise those people were doing, and at the... Full Article
si Reversing our preconceptions about where innovation comes from By feeds.bmj.com Published On :: Thu, 14 Nov 2019 16:51:19 +0000 Reverse innovation may sound like some attempt to return to the dark ages - but it has a specific meaning, especially when it comes to med-tech. It’s about where we look for innovation - and overturning our preconceived ideas of where new ideas come from. Mark Skopec, and Matthew Harris - both from Imperial College London are two of the authors... Full Article
si Is it possible to have fair pricing for medicines By feeds.bmj.com Published On :: Fri, 17 Jan 2020 17:50:54 +0000 Is it possible to have a fair price for medicines? Yes, according to a new collection just published on bmj.com. The authors set out to evaluate how we could improve the functioning of the market for medicines, to honestly compensate industry for innovation, whilst allowing the poorest to afford them. Suerie Moon, co-director of global health at... Full Article
si Talk Evidence - Sepsis, talc and blindsided by blinding By feeds.bmj.com Published On :: Wed, 22 Jan 2020 17:40:40 +0000 Welcome to the festive talk evidence, giving you a little EBM to take you into the new year. As always Duncan Jarvies is joined by Helen Macdonald (resting GP and editor at The BMJ) and Carl Heneghan (active GP, director of Oxford University’s CEBM and editor of BMJ Evidence)* This month: (1.20) Carl tells us about new research on treating... Full Article
si Writing a good outpatient letter means addressing it to the patient By feeds.bmj.com Published On :: Fri, 07 Feb 2020 11:31:30 +0000 In many countries (including the UK and Australia) it is still common practice for hospital doctors to write letters to patients’ general practitioners (GPs) following outpatient consultations, and for patients to receive copies of these letters. However, Hugh Rayner, consultant nephrologist, and Peter Rees, former Chair of the Academy of... Full Article
si Talk Evidence - Remdesivir, care homes, and death data By feeds.bmj.com Published On :: Fri, 17 Apr 2020 15:00:49 +0000 For the next few months Talk Evidence is going to focus on the new corona virus pandemic. There is an enormous amount of uncertainty about the disease, what the symptoms are, fatality rate, treatment options, things we shouldn't be doing. We're going to try to get away from the headlines and talk about what we need to know - to hopefully give... Full Article
si Talk Evidence - covid ethics, waste and a minimum RCT size By feeds.bmj.com Published On :: Fri, 24 Apr 2020 16:19:18 +0000 For the next few months Talk Evidence is going to focus on the new corona virus pandemic. There is an enormous amount of uncertainty about the disease, what the symptoms are, fatality rate, treatment options, things we shouldn't be doing. We're going to try to get away from the headlines and talk about what we need to know - to hopefully give... Full Article
si Glucose-Induced Reactive Oxygen Species Cause Apoptosis of Podocytes and Podocyte Depletion at the Onset of Diabetic Nephropathy By diabetes.diabetesjournals.org Published On :: 2006-01-01 Katalin SusztakJan 1, 2006; 55:225-233Complications Full Article
si Prospective Analysis of The Insulin-Resistance Syndrome (Syndrome X) By diabetes.diabetesjournals.org Published On :: 1992-06-01 Steven M HaffnerJun 1, 1992; 41:715-722Original Article Full Article
si Fuel selection in human skeletal muscle in insulin resistance: a reexamination By diabetes.diabetesjournals.org Published On :: 2000-05-01 DE KelleyMay 1, 2000; 49:677-683Articles Full Article
si Diabetes and Cardiovascular Disease: The "Common Soil" Hypothesis By diabetes.diabetesjournals.org Published On :: 1995-04-01 Michael P SternApr 1, 1995; 44:369-374Perspectives in Diabetes Full Article
si Morbidity and Mortality in Diabetics In the Framingham Population: Sixteen Year Follow-up Study By diabetes.diabetesjournals.org Published On :: 1974-02-01 Mariano J GarciaFeb 1, 1974; 23:105-111Original Contribution Full Article
si Moving GLUT4: The Biogenesis and Trafficking of GLUT4 Storage Vesicles By diabetes.diabetesjournals.org Published On :: 1997-11-01 Shane ReaNov 1, 1997; 46:1667-1677Perspectives in Diabetes Full Article
si High Incidence of Metabolically Active Brown Adipose Tissue in Healthy Adult Humans: Effects of Cold Exposure and Adiposity By diabetes.diabetesjournals.org Published On :: 2009-07-01 Masayuki SaitoJul 1, 2009; 58:1526-1531Metabolism Full Article
si Endothelial Progenitor Cell Dysfunction: A Novel Concept in the Pathogenesis of Vascular Complications of Type 1 Diabetes By diabetes.diabetesjournals.org Published On :: 2004-01-01 Cindy J.M. LoomansJan 1, 2004; 53:195-199Complications Full Article
si Thiazolidinediones in the Treatment of Insulin Resistance and Type II Diabetes By diabetes.diabetesjournals.org Published On :: 1996-12-01 Alan R SaltielDec 1, 1996; 45:1661-1669Perspectives in Diabetes Full Article
si Relation Between Antioxidant Enzyme Gene Expression and Antioxidative Defense Status of Insulin-Producing Cells By diabetes.diabetesjournals.org Published On :: 1997-11-01 Markus TiedgeNov 1, 1997; 46:1733-1742Original Article Full Article
si Are the {beta}-Cell Signaling Molecules Malonyl-CoA and Cystolic Long-Chain Acyl-CoA Implicated in Multiple Tissue Defects of Obesity and NIDDM? By diabetes.diabetesjournals.org Published On :: 1996-03-01 Marc PrentkiMar 1, 1996; 45:273-283Original Article Full Article
si Intramyocellular triglyceride content is a determinant of in vivo insulin resistance in humans: a 1H-13C nuclear magnetic resonance spectroscopy assessment in offspring of type 2 diabetic parents By diabetes.diabetesjournals.org Published On :: 1999-08-01 G PerseghinAug 1, 1999; 48:1600-1606Articles Full Article
si Mechanisms of Pancreatic {beta}-Cell Death in Type 1 and Type 2 Diabetes: Many Differences, Few Similarities By diabetes.diabetesjournals.org Published On :: 2005-12-01 Miriam CnopDec 1, 2005; 54:S97-S107Section III: Inflammation and beta-Cell Death Full Article
si Tumor Necrosis Factor {alpha}: A Key Component of the Obesity-Diabetes Link By diabetes.diabetesjournals.org Published On :: 1994-11-01 Gökhan S HotamisligilNov 1, 1994; 43:1271-1278Perspectives in Diabetes Full Article
si Intrauterine exposure to diabetes conveys risks for type 2 diabetes and obesity: a study of discordant sibships By diabetes.diabetesjournals.org Published On :: 2000-12-01 D DabeleaDec 1, 2000; 49:2208-2211Articles Full Article
si Lipotoxicity in the Pathogenesis of Obesity-Dependent NIDDM: Genetic and Clinical Implications By diabetes.diabetesjournals.org Published On :: 1995-08-01 Roger H UngerAug 1, 1995; 44:863-870Perspectives in Diabetes Full Article
si Lipid-Induced Insulin Resistance in Human Muscle Is Associated With Changes in Diacylglycerol, Protein Kinase C, and I{kappa}B-{alpha} By diabetes.diabetesjournals.org Published On :: 2002-07-01 Samar I. ItaniJul 1, 2002; 51:2005-2011Rapid Publications Full Article
si Exendin-4 stimulates both beta-cell replication and neogenesis, resulting in increased beta-cell mass and improved glucose tolerance in diabetic rats By diabetes.diabetesjournals.org Published On :: 1999-12-01 G XuDec 1, 1999; 48:2270-2276Articles Full Article
si Elevated Levels of Acute-Phase Proteins and Plasminogen Activator Inhibitor-1 Predict the Development of Type 2 Diabetes: The Insulin Resistance Atherosclerosis Study By diabetes.diabetesjournals.org Published On :: 2002-04-01 Andreas FestaApr 1, 2002; 51:1131-1137Complications Full Article
si The Relationship of Glycemic Exposure (HbA1c) to the Risk of Development and Progression of Retinopathy in the Diabetes Control and Complications Trial By diabetes.diabetesjournals.org Published On :: 1995-08-01 The Diabetes Control and Complications Trial Research GroupAug 1, 1995; 44:968-983Original Article Full Article
si PPAR{gamma} Ligands Increase Expression and Plasma Concentrations of Adiponectin, an Adipose-Derived Protein By diabetes.diabetesjournals.org Published On :: 2001-09-01 Norikazu MaedaSep 1, 2001; 50:2094-2099Pathophysiology Full Article
si Preservation of Pancreatic {beta}-Cell Function and Prevention of Type 2 Diabetes by Pharmacological Treatment of Insulin Resistance in High-Risk Hispanic Women By diabetes.diabetesjournals.org Published On :: 2002-09-01 Thomas A. BuchananSep 1, 2002; 51:2796-2803Pathophysiology Full Article
si Free fatty acid-induced insulin resistance is associated with activation of protein kinase C theta and alterations in the insulin signaling cascade By diabetes.diabetesjournals.org Published On :: 1999-06-01 ME GriffinJun 1, 1999; 48:1270-1274Articles Full Article
si Role of Fatty Acids in the Pathogenesis of Insulin Resistance and NIDDM By diabetes.diabetesjournals.org Published On :: 1997-01-01 Guenther BodenJan 1, 1997; 46:3-10Perspectives in Diabetes Full Article
si U.K. Prospective Diabetes Study 16: Overview of 6 Years' Therapy of Type II Diabetes: A Progressive Disease By diabetes.diabetesjournals.org Published On :: 1995-11-01 U.K. Prospective Diabetes Study GroupNov 1, 1995; 44:1249-1258Perspectives in Diabetes Full Article
si The Triumvirate: {beta}-Cell, Muscle, Liver: A Collusion Responsible for NIDDM By diabetes.diabetesjournals.org Published On :: 1988-06-01 Ralph A DeFronzoJun 1, 1988; 37:667-687Lilly Lecture 1987 Full Article
si Quantification of the Relationship Between Insulin Sensitivity and {beta}-Cell Function in Human Subjects: Evidence for a Hyperbolic Function By diabetes.diabetesjournals.org Published On :: 1993-11-01 Steven E KahnNov 1, 1993; 42:1663-1672Original Article Full Article
si Isolation of INS-1-derived cell lines with robust ATP-sensitive K+ channel-dependent and -independent glucose-stimulated insulin secretion By diabetes.diabetesjournals.org Published On :: 2000-03-01 HE HohmeierMar 1, 2000; 49:424-430Articles Full Article
si Changes in Gut Microbiota Control Metabolic Endotoxemia-Induced Inflammation in High-Fat Diet-Induced Obesity and Diabetes in Mice By diabetes.diabetesjournals.org Published On :: 2008-06-01 Patrice D. CaniJun 1, 2008; 57:1470-1481Metabolism Full Article
si Metabolic Endotoxemia Initiates Obesity and Insulin Resistance By diabetes.diabetesjournals.org Published On :: 2007-07-01 Patrice D. CaniJul 1, 2007; 56:1761-1772Obesity Studies Full Article
si Classification and Diagnosis of Diabetes Mellitus and Other Categories of Glucose Intolerance By diabetes.diabetesjournals.org Published On :: 1979-12-01 National Diabetes Data GroupDec 1, 1979; 28:1039-1057Articles Full Article
si {beta}-Cell Deficit and Increased {beta}-Cell Apoptosis in Humans With Type 2 Diabetes By diabetes.diabetesjournals.org Published On :: 2003-01-01 Alexandra E. ButlerJan 1, 2003; 52:102-110Islet Studies Full Article
