A seamless sheet installation system preferably includes a seamless sheet and a plurality of sheet retention devices. The seamless sheet is retained on a tube. A pair of rotating retention devices may be inserted into ends of the roll. Each rolling retention device includes a tube plug and a rotating handle. An end of the seamless sheet is secured to the top eave flange. The seamless sheet is held against a bottom of the eave purlin web with one of the plurality of sheet retention devices. The sheet retention device may have any suitable design. The seamless sheet is rolled out to successive purlins, wrapped over the top flange and anchored to a bottom of the vertical web with one of the plurality of sheet retention devices. The seamless sheet wrapping process is terminated at an opposing eave purlin or a ridge purlin. Insulation is then inserted between adjacent purlins.

Conventional gas mask seals or gaskets are merely rubber flaps integral to and extending from the main body or shell of a gas mask that are conformed to the face of a wearer by tightening straps. The described gas masks comprise a separate gas mask seal and a gas mask shell. Some of the gas mask seals are individualized or customized to more tightly fit and conform to the face of the individual wearer and to provide greater comfort and protection. The gas mask seals may be made from three-dimensional image files developed directly from the wearer's facial features.

Systems and methods for longevity, anti-aging, fatigue management, obesity, weight loss, weight management, delivery of nutraceuticals, and treating hyperglycemia, Alzheimer's disease, sleep disorders, Parkinson's disease, Attention Deficit Disorder and nicotine addiction involve synchronizing and tailoring the administration of nutraceuticals, medications and other substances in accordance with the body's natural circadian rhythms, meal times and other factors. Improved control of blood glucose levels, extended alertness, and weight control, and counteracting of disease symptoms when they are at their worst are possible. An automated, pre-programmable transdermal administration system is used to provide pulsed doses of medications, pharmaceuticals, hormones, neuropeptides, anorexigens, pro-drugs, stimulants, nutraceuticals, phytochemicals, phytonutrients, enzymes, antioxidants, essential oils, fatty acids, minerals, vitamins, amino acids, coenzymes, or other physiological active ingredient or precursor. The system can utilize a pump, pressurized reservoir, a system for removing depleted carrier solution, or other modulated dispensing actuator, in conjunction with porous membranes or micro-fabricated structures.

Disclosed herein is a fluid infusion device of the type that delivers medication fluid to the body of a patient. The device includes or cooperates with a fluid reservoir, and the device has a sealing assembly to receive and form a fluid seal with the fluid reservoir. A retractable sealing element surrounding a hollow fluid delivery needle may be used to seal a port of the fluid reservoir. The port may include a pressure vent that is sealed by the retractable sealing element. In one variation, the reservoir includes a moving valve sleeve that holds a septum. The septum moves to allow the reservoir to vent, and to form a seal with the port when the needle pierces the septum. In another variation, the device includes a needleless sealing assembly. In yet other variations, the device uses a needled fluid reservoir.

System and method for control of a subsea located cyclone for separating oil from water. The cyclone is arranged to receive water with oil contents through an inlet line, the oil is separated from the water and delivered through an oil outlet to an oil outlet line, and the water is delivered through a water outlet to a water outlet line. The system is comprising a control valve in the oil outlet or oil outlet line from the cyclone, a first differential pressure transducer arranged between the inlet line and the oil outlet from the cyclone, and a second differential pressure transducer arranged between the inlet line and the water outlet from the cyclone. The system is distinguished in that a sensor for measuring oil contents is arranged in the water outlet or water outlet line, and via a control means said sensor is operatively connected to the control valve.

An assay and a method for identifying a prebiotic to treat a subject in need thereof to promote intestinal barrier integrity or to blunt an inflammatory response are provided.

Methods and compositions are described for categorizing and treating autoimmune disease, using single cell network profiling (SCNP), where activation levels of one or more activatable elements are determined in single cells, with or without modulation, to categorize or determine treatment for the autoimmune disease.

This invention publicizes a chronic renal disease diagnostic kit, comprised of FGF23 monoclonal antibody, biotin labeling reagent Sulfo-NHS-LC-Biotin, PBS buffer solution (pH7.0, 0.1M), casein saline solution, streptomycin avidin and substrate TMB. The labeling condition is the weight ratio of FGF23 antibody and Sulfo-NHS-LC-Biotin, which is 1:5-1:12. The dilution ratio of streptomycin avidin is 1:3000. The lowest testing threshold limit value of FGF23 kit is 10 pg/ml, whose sensitivity is 10 times higher than that of common monoclonal antibody, which is very significant for early diagnose of chronic renal disease.

In sporadic Alzheimer's disease, neurofibrillary lesion formation is preceded by extensive post-translational modification of the microtubule associated protein tau. Immunoassays have been developed recently that detect tau in biological specimens, thus providing a means for pre-mortem diagnosis of Alzheimer's disease, which has remained elusive. These assays have been improved by the analysis of relevant post-translational modifications, such as phosphorylation, however opportunity for improvement remains. The present invention addresses this issue by disclosing synthetic methylated peptides derived from the tau protein of paired helical filaments and non-diseased control brain. Alzheimer's disease specificity is provided by the presence or absence of methyl moieties on lysine residues and differences between mono-, di-, and tri-methylation. The methylated peptide is useful as an antigen and a binding partner for identifying compounds that interact with the peptide and the methylated tau protein, including antibodies that can distinguish non-diseased brain from that affected by Alzheimer's disease. The resulting antibodies are useful diagnostically and therapeutically. The compounds that specifically bind to methylated tau proteins are useful for eliminating abnormally methylated tau.

East Bay resident Miles Woodruff, CEO of the pioneering vegan-seafood brand Sophie's Kitchen, has just donated 3,000 cases of plant-based Toona to the Food Bank of Contra Costa and Solano County as well as several other Bay Area food shelters.

Amidst the Covid-19 outbreak, the company's brand-new Lemon Grass Toona flavor has not yet arrived in grocery stores — but 100 percent of it is now being provided to people in need.…

A method and a device for heat sealing multiple plies of a laminate from which gable top packaging can be produced, wherein the laminate has a carrier layer made of electrically non-conductive material and a sealing layer made of thermoplastic material on at least one surface of the laminate. To heat seal multiple plies of a laminate in a high-frequency alternating electric field, the alternating electric field is generated by a first lead of an HF voltage supply in a first sub-region of the sealing region and is generated by a second lead of the HF voltage supply, differing from the first lead, in at least a second sub-region of the sealing region, so that a different heat distribution is obtained over the sub-regions of the sealing region.

News you don't want to miss for April 14:

1. Six of the 15 confirmed covid-19 cases at Santa Rita Jail have recovered, the East Bay Times reports.…

AN ICONIC Hampshire hotel which closed its doors after going into administration has been bought by an international hotelier.

Saints bag themselves a well deserved point at Stamford Bridge after Dusan Tadic equalises with a penalty.

Pictures from Southampton v Swansea.

View the Barclays Premier League clash between Chelsea and Saints via our picture gallery

WATERSIDE angler Arran Harmer was rewarded with a personal best pike of 23lb 2oz when he tackled a Southern Stillwater.

A 9lb bull huss bagged by Adrian Moody from the Waterside was the highlight when the Lymington club staged a shallow boat competition, writes Chris Clark.

On some occasions, we earn revenue from content. This commercial content is compiled via expert opinion. Clicking in certain hyperlinks within this article will redirect you to a 3rd party. 

updating with pars 15 & 16.

THIS week I wanted to do something a bit different by revisiting two of my most memorable games since joining Saints back in 2016.

THE largest producing community theatre in Europe is looking forward to a season of new plays in 2021.

AFC TOTTON fear midfielder Liam Crook’s season may be over.

ANDY Samuels is standing down as manager of Sydenhams Wessex One side Romsey Town at the end of the season.

Daily Echo gaming reviewer Ian Crump reviews the latest games.

HAMPSHIRE racing starlet Brody Crockford has followed in his father’s tyre marks after completing his debut MiniGP50 Motorcycle British Championship in spectacular style.

MOTORCYCLE racing starlet Brody Crockford has already made his mark within the British SuperBike paddock with impressive performances in the Dickies British Junior Supersport championship.

To wrap up our 40 Years of Jazz celebration, WEMU is inviting area musicians and jazz fans to come in the studio and be a Guest DJ. Today’s guest was drummer Sean Dobbins. Sean remembers years ago when his main musical mentor, trumpeter, and teacher Louis Smith told Sean to listen to WEMU to hear more of the music he wanted to play. WEMU has been a big part of Sean’s life and Sean has been a big player in our sound and programming for years.

The Sahara – the world’s largest desert – was once underwater. Now a 20-year study led by a Stony Brook University professor has profiled the aquatic animals that once lived there.

Video games often get a bad rap for isolating young people. However, they might be an effective treatment for older adults with depression. Scientists from several universities, including the University of Connecticut, are investigating.

Cold Spring Harbor Laboratory has won a $750,000 grant from TD Bank to support its new cancer research facility.

The GOP has flipped two of the five Connecticut General Assembly seats left vacant by Democratic incumbents who resigned to take jobs in Governor Ned Lamont’s new administration.

Connecticut Governor Ned Lamont has announced a shakeup in his office staff. It comes after Lamont had some challenges getting lawmakers to support some of his agenda in his first legislative session.

Copyright 2018 NPR. To see more, visit (SOUNDBITE OF MUSIC) SCOTT SIMON, HOST: And to the uplifting notes of B.J. Leiderman, who writes our theme music, Major League Baseball is headed into the final weeks of the regular season. Mercy, is there a race in the NL Central. Howard Bryant of ESPN and espn.com joins us. Howard, thanks for being with us. HOWARD BRYANT, BYLINE: Good morning, Scott. SIMON: Oh, it is a good morning. The Cubs defeated the Reds - I mean the Cincinnati baseball team, not the KGB - 3-2. The Brewers defeated the Pirates 7-2. The Dodgers defeated the Cards 3-0. This put the Cubs a game and a half above the Brew Crew (ph) and five ahead of the Cards. These are three very worthy teams, aren't they? BRYANT: You know what, Scott? We talk so much this year about the president, and we talk about the NFL when we talk about Colin Kaepernick, and we talk about Serena and we talk about all of these things, but this has been such an underrated baseball season. And this is my

In episode two, host Will McInerney talks with reporter Reema Khrais about her personal connections to the Chapel Hill Shootings, and Will travels to the Syrian border to visit a dental clinic named in honor of Deah, Yusor, and Razan. Subscribe to this Podcast Stories with a Heartbeat is a new podcast hosted by poet Will McInerney that explores the human condition in conflict through poetry, listening, and conversation. On February 10th, 2015 Deah Barakat, his wife Yusor Abu-Salha, and her sister Razan Abu-Salha were murdered in Chapel Hill, North Carolina. All three young American-Muslims were shot and killed execution style in their home. Last episode on Stories with a Heartbeat, we relived the night of the Chapel Hill Shootings through the eyes of Deah’s brother, Farris Barakat. Shortly after that night, this story echoed around the world as the victims’ legacy was honored from Chapel Hill to the Syrian border, and concerns over hate crimes and Islamophobia moved to the forefront.

Both Robert Rodriguez and Payton Reed have been confirmed to sit behind the lens for the upcoming second installment of Disney's hit 'Star Wars' spin-off.

Weeks after COVID-19 shut down productions worldwide, Ryan Murphy admits that he has been contemplating between pushing production back by a year or changing theme.

Cast members, including Pete Davidson and Kate McKinnon, have been entertaining fans with skits and musical numbers from their self-isolation since mid-April.

Series creator Ryan Murphy reveals in a new interview that he has done writing the scripts for the new installment of the series, though the production has yet to start due to the Coronavirus pandemic.

Twenty three years after she wore the prom dress in the 'Prophecy Girl' episode, the former 'Buffy the Vampire Slayer' star delights fans with her throwback look in a new social media post.

Cast members, including Pete Davidson and Kate McKinnon, have been entertaining fans with skits and musical numbers from their self-isolation since mid-April.

Series creator Ryan Murphy reveals in a new interview that he has done writing the scripts for the new installment of the series, though the production has yet to start due to the Coronavirus pandemic.

Tyrell Reed, the uncle of the late Indianapolis rapper also known as Sean Da Don, says the officer's insensitive comment only adds pain to the family's grief.

Efforts to boost economic development and research in Flint are getting support from the U.S. Economic Development Administration.

A former Stony Brook University professor has pleaded guilty to stealing over $200,000 of government cancer research money to pay personal bills.

The inimitable Brownsville representer Sean P gives us a rundown of his long-awaited album, Mic Tyson.

See http://theciphershow.com/episode/23/ for full show notes and comments.

Sput is a drummer, keyboardist, and producer who consistently plays with the top acts in the world. Hip-hop fans have heard his work with Snoop Dogg, Timbaland, and Kendrick Lamar. But in addition to that, the Dallas native has played with everyone from Erykah Badu to Celine Dion to his main gig, the instrumental powerhouse band Snarky Puppy.

But back before all that, Sput got his start as a part of Kirk Franklin’s Grammy-winning group God’s Property, which he played in as a teenager - and whose lineup, incidentally, was a who’s-who of future star musicians.

See http://theciphershow.com/episode/155/ for full show notes and comments.

Madin walking tour led by Alan Clawley Starting at Five Ways Station, 10.30 am, 22nd June 2013