spa Maison Perron Expands Beyond Just a Vibrant Office Space in Quebec By design-milk.com Published On :: Mon, 04 Nov 2024 17:00:23 +0000 Maison Perron redefines the studio's ethos by transforming a historic Quebec building into a vibrant space that celebrates Perron’s blend of artistry and functionality. Full Article Architecture Interior Design Main Perron
spa "WE PAINT...Spaces and Faces!" By indianapublicmedia.org Published On :: 04 Oct 2024 13:00:00 GMT The Vault at Gallery Mortgage121 E 6th StreetBloomington IN 47408 Ongoing through Friday, November 22, 2024, 5pm Come enjoy the beautiful artwork by the talented artists of the Bloomington Watercolor Society. The Fall Membership Show, "Spaces and Faces" features 30 paintings by the BWS portrait and plein air painters. Gallery Hours 9-5, M-F. Receptions take place on Gallery Walk Fridays, 5-8 pm. Presenter: Bloomington Watercolor Society Annual Fall Show Contact: Jeanne Dutton Cost: Free Communities: Bedford, Bloomington, Brown County, Columbus, Greene County, Indianapolis, Martinsville, Seymour, Spencer Full Article 2024/10/04 (Fri)
spa Northwestern, U. of C. presidents talk 'safe spaces' on Katie Couric's new series By www.chicagotribune.com Published On :: Wed, 16 May 2018 15:25 -0500 President Robert J. Zimmer and Northwestern president discuss safe spaces and discourse on campus Full Article
spa A Brief History of Dinosaurs in Space By motherboard.vice.com Published On :: Thu, 31 May 2018 11:22 -0500 Prof. W.J.T. Mitchell writes book on cultural depictions of dinosaurs Full Article
spa Sky Crew: Missions to Venus, Space Junk & UFOs By www.nhpr.org Published On :: Wed, 09 Jun 2021 11:37:00 -0400 Our Sky Crew returns for a send-off for Laura Knoy’s last show as Exchange host. The Sky Crew will be at their telescopes in the wee hours prior to the show checking out the partial solar eclipse visible in our area. We discuss the goals of NASA’s newly-announced missions to our nearest planetary neighbor, Venus, the growing problem of space junk, and what to think about UFOs. Full Article
spa Anna Kikina: Russia's only woman cosmonaut tames SpaceX Crew Dragon By english.pravda.ru Published On :: Thu, 06 Oct 2022 20:02:00 +0300 On October 5, SpaceX Crew Dargon blasted off to the International Space Station. Anna Kikina, a woman cosmonaut from Russia, was on board the SpaceX spacecraft. "A SpaceX Falcon 9 rocket propelled the Dragon Endurance spacecraft into orbit carrying NASA astronauts Nicole Mann as mission commander, and Josh Cassada, pilot. JAXA (Japan Aerospace Exploration Agency) astronaut Koichi Wakata and Roscosmos cosmonaut Anna Kikina, also aboard the Dragon, will serve as mission specialists for their science expedition in microgravity aboard the space station," NASA wrote. The participation of a Russian cosmonaut in the launch launch was made possible owing to the cross-flight programme: a Russian cosmonaut boarded SpaceX, and an American astronaut flew to the ISS on board a Soyuz spacecraft. Full Article Society
spa What does the future hold for International Space Station? By english.pravda.ru Published On :: Tue, 12 Jan 2021 20:19:00 +0300 The future of the International Space Station remains extremely vague. News reports about technical problems on board the ISS became, one might say, traditional. Is it time to decide? The service life of the International Space Station extends till 2024. At the same time, now is the time to decide what should be done to the station afterwards. Late last year, Deputy Prime Minister Yuri Borisov said that the future of the ISS would be determined in the first quarter of 2021."The fate of the ISS has not been fully decided yet, it will be determined, probably, in the first quarter of next year," Borisov told TASS. He also added that Roscosmos corporation plans to launch a new segment of the ISS, which is expected to become the basis for the Russian orbital station in the future.It goes about "Nauka" ("Science") module, which will become a space laboratory for Russian cosmonauts. Does Russia want the ISS to last longer? Ivan Moiseev, the scientific director of the Institute of Space Policy, believes that stopping international cooperation was out of the question. "There is an official permit to run the station till 2024 - till 2025, in fact. All the countries participating in the ISS agreement agreed to consider the issue of extending the service life of the station till 2028-2030 - that was six months ago," the expert told Pravda.Ru.However, the situation took a turn due to a series of accidents on board the ISS."Those were insignificant accidents, but they create a relevant information background. The government had to decide. If it was not for those accidents, they would have quietly extended the service life of the ISS until 2028, and it would be beneficial to everyone. But when those accidents started happening, they led the general public to believe that the station was falling apart. There were official statements made about the need to finish its work," Ivan Moiseev said.However, the expert believes that the work of the station should be extended. "Therefore, the government apparently will make a decision on the matter in early 2021," he believes. Full Article Science
spa Russia gets involved in the new space race By english.pravda.ru Published On :: Tue, 20 Apr 2021 21:26:00 +0300 In 2025, the era of the International Space Station is supposed to end. Russia, China and the United States will switch to their own programs in near space. All space powers have their problems. Who is going to win the race? Russia to flood its section of the ISS in 2024 Roscosmos CEO Dmitry Rogozin wrote in Telegram that the Russian Space Agency started working on the construction of the first module of the new Russian orbital station. "The work on the first base module for the new Russian orbital service station is underway. The Energia Rocket and Space Corporation has been tasked to ensure its readiness for launch into orbit in 2025," Rogozin wrote. Full Article Science
spa Russia is losing space power status with the launch of Nauka module to ISS By english.pravda.ru Published On :: Thu, 22 Jul 2021 20:09:00 +0300 Russia is making pointless and even strange steps in and around space, and they are all the more sad because they cost the Russian budget a lot of money and deprive the nation of the space power status. Why the United States would like to work with Russia in space, but Russia would not The space race has been getting increasingly intense lately. Different countries declare their claims to the Moon. It appears that China is going to be the first to go there. The exploration or even the colonisation of Mars is next on the list. Space exploration by private corporations is in full swing: Full Article Science
spa Video shows highly professional rescue of woman and her dog from flooded home in Spain By english.pravda.ru Published On :: Wed, 30 Oct 2024 13:44:00 +0300 A woman trapped in her flooded home in Utiel, Valencia, was rescued with her dog. The video of her salvation shows the professionalism of Spanish rescuers. At least 51 people were killed in Spain's autonomous community of Valencia due to heavy rains and floodwaters, the Single Operations Coordination Centre (Cecopi) said. Rescuers found the lifeless bodies of five people in the town of Torrent: a couple, two children and a baby. Four bodies were found in Paiport: two men, a woman and a child. Victims were also reported in Chiva, Cheste, Alfafar and Alcudia. Full Article Incidents
spa Launch of Soyuz MS-25 manned spacecraft to ISS aborted at the last moment By english.pravda.ru Published On :: Thu, 21 Mar 2024 19:19:00 +0300 On Thursday, March 21, the Soyuz-2.1a rocket with the Soyuz MS-25 manned spacecraft was supposed to blast off from launch pad No. 31 (Vostok) at Baikonur Cosmodrome. The rocket launch was aborted at the last moment. The countdown was stopped approximately 20 seconds before the start time. "Attention at the launch complex. The launch was automatically aborted. Bring the units of the launch complex to their original condition. Prepare to be parked for 24 hours,” the announcer of the broadcast hosted by Roscosmos said. The launch was dedicated to the 90th anniversary of Soviet cosmonaut and first man in space Yuri Gagarin. Full Article Science
spa Russia's first Angara space launch vehicle finally launched at third attempt By english.pravda.ru Published On :: Thu, 11 Apr 2024 16:11:00 +0300 The Orion upper stage of the Angara-A5 heavy rocket launched the Gagarinets small satellite into low Earth orbit, Roscosmos said on its Telegram channel. "The Cubesat 3U format satellite was created by Russian private company Avant Space and is intended to test elements of the service platform,” the state corporation said. After the launch of the Gagarinets, the upper stage continued its work. Full Article Science
spa China sends three taikonauts on board Shenzhou-19 spacecraft into orbit By english.pravda.ru Published On :: Wed, 30 Oct 2024 14:07:00 +0300 Chinese manned spacecraft Shenzhou-19 with three taikonauts on board was successfully launched into low-Earth orbit from the Jiuquan Satellite Launch Center in northwestern China, UDN Global reports. The spacecraft blasted off on October 29 at 23:27 Moscow time, or October 30 at 04:27 local time. A Long March 2 °F-19 launch vehicle was used for the liftoff. About ten minutes into the flight, the Shenzhou-19 manned spacecraft successfully separated from the rocket and flew into orbit. There are three crew members on board the Shenzhou-19. They will conduct 86 scientific experiments in space, including experiments in the field of medicine, biology, fundamental physics of microgravity, materials science and space technology, the agency notes. Full Article Science
spa Decentralization, corruption, negligence: Causes of humanitarian disaster in Spain By english.pravda.ru Published On :: Thu, 07 Nov 2024 17:46:00 +0300 The Spanish authorities allowed a humanitarian disaster to occur in Valencia when a catastrophic flood hit the region. The government of Spain pays first priority to Ukraine, rather to its own people. Humanitarian crisis in Valencia due to government inaction On October 29, torrential rains hit Valencia inundating dry riverbeds and ravines filled with dead wood and debris. Floodwaters went upstream under pressure trapping thousands of people. To date, 217 bodies have been identified. According to European satellite emergency assistance system Copernicus EMS, the floods affected 15,633 hectares of land, including 3,249 kilometers of streets and roads. Over 190,000 people were affected, 17,597 residential buildings were ruined or partially damaged. Hospitals of the region work in overdrive due to disrupted logistics. Full Article World
spa Extend the Lifespan of Your Gadgets - A Comprehensive Maintenance Checklist By www.retailtechnologyreview.com Published On :: By George Freeman, freelance writer.In our fast-paced world, electronic devices have become integral to our daily lives. From smartphones and tablets to laptops and smartwatches, these gadgets keep us connected, entertained, and productive. However, the wear and tear of regular use can take a toll on our beloved devices. Full Article Critical Issues Mobile Computers
spa The Ergonomic Solutions Group’s new SpacePole Kiosk – A modular, configurable and customisable platform for a wide range of self-service applications By www.retailtechnologyreview.com Published On :: Tue, 13 Nov 4040 16:52:00 +0000 The Ergonomic Solutions Group, the designer and manufacturer of technology mounting solutions, has launched the SpacePole Kiosk – described as a multifunctional platform with maximum flexibility for a wide range of self-service applications including self-check-in/check-out, self-ordering, endless aisle, product display & advertising, ticketing, click & collect and many more. Full Article Kiosk Technology
spa Defense Chiefs of S. Korea, US Condemn Dispatching of N. Korean Troops in ‘Strongest Terms’ By world.kbs.co.kr Published On :: Thu, 31 Oct 2024 08:31:24 +0900 [Inter-Korea] : The defense chiefs of South Korea and the United States have condemned the deployment of North Korean troops to Russia in the “strongest” terms with “one voice.” Defense Minister Kim Yong-hyun and U.S. Secretary of Defense Lloyd Austin issued the condemnation on Wednesday in a joint statement after ...[more...] Full Article Inter-Korea
spa S. Korea, US to Launch Solar Observation Instrument to Int’l Space Station By world.kbs.co.kr Published On :: Fri, 01 Nov 2024 14:15:21 +0900 [Science] : South Korea and the United States will launch a jointly developed instrument to the International Space Station(ISS) to help scientists learn more about the solar wind. According to the Korea AeroSpace Administration and the Korea Astronomy and Space Science Institute, the Coronal Diagnostic ...[more...] Full Article Science
spa Space Agency to Develop Lunar Module to be Sent to Moon by 2032 By world.kbs.co.kr Published On :: Mon, 04 Nov 2024 17:44:41 +0900 [Science] : The Korea AeroSpace Administration and the Korea Aerospace Research Institute are set to proceed with the development of a lunar module after signing an agreement on the second phase of the nation’s moon exploration project. According to the state agency on Monday, some 530 billion won, or around 386 ...[more...] Full Article Science
spa S. Korea’s Telecom Satellite Koreasat-6A Launched from US Space Center By world.kbs.co.kr Published On :: Tue, 12 Nov 2024 09:48:52 +0900 [Science] : A telecommunication satellite from the South Korean telecom giant KT has been launched into space and is now in orbit. According to a launch video from SpaceX, the Koreasat-6A, a geostationary satellite for communication services, was launched aboard SpaceX’s Falcon 9 rocket from the Kennedy Space ...[more...] Full Article Science
spa [4K] aespa, THE BOYZ, ITZY, STAYC, Kep1er, FIFTY FIFTY, tripleS VV, SAY MY NAME | On the way to music bank 241101 By world.kbs.co.kr Published On :: 2024-11-01 +09:00 On the morning of November 1, at Yeoido KBS HallKBS WORLD Radio filmed K-pop stars making their way to attend rehearsals for Music Bank.[more...] Full Article Economy&It
spa Washington DC among US cities most vulnerable to space weather, scientists say - The Royal Astronomical Society By news.google.com Published On :: Thu, 18 Jul 2024 07:00:00 GMT Washington DC among US cities most vulnerable to space weather, scientists say The Royal Astronomical Society Full Article
spa Studying multi-hazards from space - British Geological Survey By news.google.com Published On :: Fri, 31 May 2024 08:09:03 GMT Studying multi-hazards from space British Geological Survey Full Article
spa Monitoring coastal change from space - British Geological Survey By news.google.com Published On :: Thu, 10 Oct 2024 14:36:15 GMT Monitoring coastal change from space British Geological Survey Full Article
spa GraphT–T (V1.0Beta), a program for embedding and visualizing periodic graphs in 3D Euclidean space By journals.iucr.org Published On :: 2024-04-29 Following the work of Day & Hawthorne [Acta Cryst. (2022), A78, 212–233] and Day et al. [Acta Cryst. (2024), A80, 258–281], the program GraphT–T has been developed to embed graphical representations of observed and hypothetical chains of (SiO4)4− tetrahedra into 2D and 3D Euclidean space. During embedding, the distance between linked vertices (T–T distances) and the distance between unlinked vertices (T⋯T separations) in the resultant unit-distance graph are restrained to the average observed distance between linked Si tetrahedra (3.06±0.15 Å) and the minimum separation between unlinked vertices is restrained to be equal to or greater than the minimum distance between unlinked Si tetrahedra (3.713 Å) in silicate minerals. The notional interactions between vertices are described by a 3D spring-force algorithm in which the attractive forces between linked vertices behave according to Hooke's law and the repulsive forces between unlinked vertices behave according to Coulomb's law. Embedding parameters (i.e. spring coefficient, k, and Coulomb's constant, K) are iteratively refined during embedding to determine if it is possible to embed a given graph to produce a unit-distance graph with T–T distances and T⋯T separations that are compatible with the observed T–T distances and T⋯T separations in crystal structures. The resultant unit-distance graphs are denoted as compatible and may form crystal structures if and only if all distances between linked vertices (T–T distances) agree with the average observed distance between linked Si tetrahedra (3.06±0.15 Å) and the minimum separation between unlinked vertices is equal to or greater than the minimum distance between unlinked Si tetrahedra (3.713 Å) in silicate minerals. If the unit-distance graph does not satisfy these conditions, it is considered incompatible and the corresponding chain of tetrahedra is unlikely to form crystal structures. Using GraphT–T, Day et al. [Acta Cryst. (2024), A80, 258–281] have shown that several topological properties of chain graphs influence the flexibility (and rigidity) of the corresponding chains of Si tetrahedra and may explain why particular compatible chain arrangements (and the minerals in which they occur) are more common than others and/or why incompatible chain arrangements do not occur in crystals despite being topologically possible. Full Article text
spa Duality of spaces and the origin of integral reflection conditions By journals.iucr.org Published On :: The reciprocal of a non-primitive unit cell is not a unit cell and the basis vectors do not correspond to cell lengths. Full Article text
spa Animations, videos and 3D models for teaching space-group symmetry By journals.iucr.org Published On :: Animations, videos and 3D models have been designed to visualize the effects of symmetry operators on selected cases of crystal structures, pointing out the relationship with the diagrams published in International Tables for Crystallography, Vol. A. Full Article text
spa Animations, videos and 3D models for teaching space-group symmetry By journals.iucr.org Published On :: 2024-10-16 A series of animations, videos and 3D models that were developed, filmed or built to teach the symmetry properties of crystals are described. At first, these resources were designed for graduate students taking a basic crystallography course, coming from different careers, at the National Autonomous University of Mexico. However, the COVID-19 pandemic had the effect of accelerating the generation of didactic material. Besides our experience with postgraduate students, we have noted that 3D models attract the attention of children, and therefore we believe that these models are particularly useful for teaching children about the assembled arrangements of crystal structures. Full Article text
spa Duality of spaces and the origin of integral reflection conditions By journals.iucr.org Published On :: 2024-10-16 The dualism between direct and reciprocal space is at the origin of well known relations between basis vectors in the two spaces. It is shown that when a coordinate system corresponding to a non-primitive unit cell is adopted, this dualism has to be handled with care. In particular, the reciprocal of a non-primitive unit cell is not a unit cell but a region in reciprocal space that does not represent a unit of repetition by translation. The basis vectors do not correspond to reciprocal-space cell lengths, contrary to what is stated even in the core CIF dictionary. The corresponding unit cell is a multiple of this region. The broken correspondence between basis vectors and unit cell is at the origin of the integral reflection conditions. Full Article text
spa Performance of a photoelectron momentum microscope in direct- and momentum-space imaging with ultraviolet photon sources By journals.iucr.org Published On :: 2024-01-01 The Photoelectron-Related Image and Nano-Spectroscopy (PRINS) endstation located at the Taiwan Photon Source beamline 27A2 houses a photoelectron momentum microscope capable of performing direct-space imaging, momentum-space imaging and photoemission spectroscopy with position sensitivity. Here, the performance of this microscope is demonstrated using two in-house photon sources – an Hg lamp and He(I) radiation – on a standard checkerboard-patterned specimen and an Au(111) single crystal, respectively. By analyzing the intensity profile of the edge of the Au patterns, the Rashba-splitting of the Au(111) Shockley surface state at 300 K, and the photoelectron intensity across the Fermi edge at 80 K, the spatial, momentum and energy resolution were estimated to be 50 nm, 0.0172 Å−1 and 26 meV, respectively. Additionally, it is shown that the band structures acquired in either constant energy contour mode or momentum-resolved photoemission spectroscopy mode were in close agreement. Full Article text
spa Similarity score for screening phase-retrieved maps in X-ray diffraction imaging – characterization in reciprocal space By journals.iucr.org Published On :: 2024-01-01 X-ray diffraction imaging (XDI) is utilized for visualizing the structures of non-crystalline particles in material sciences and biology. In the structural analysis, phase-retrieval (PR) algorithms are applied to the diffraction amplitude data alone to reconstruct the electron density map of a specimen particle projected along the direction of the incident X-rays. However, PR calculations may not lead to good convergence because of a lack of diffraction patterns in small-angle regions and Poisson noise in X-ray detection. Therefore, the PR calculation is still a bottleneck for the efficient application of XDI in the structural analyses of non-crystalline particles. For screening maps from hundreds of trial PR calculations, we have been using a score and measuring the similarity between a pair of retrieved maps. Empirically, probable maps approximating the particle structures gave a score smaller than a threshold value, but the reasons for the effectiveness of the score are still unclear. In this study, the score is characterized in terms of the phase differences between the structure factors of the retrieved maps, the usefulness of the score in screening the maps retrieved from experimental diffraction patterns is demonstrated, and the effective resolution of similarity-score-selected maps is discussed. Full Article text
spa Increased spatial coherence length from an asymmetric crystal reflection at grazing exit By journals.iucr.org Published On :: 2024-03-26 Coherent X-ray imaging is an active field at synchrotron sources. The images rely on the available coherent flux over a limited field of view. At many synchrotron beamlines a double-crystal monochromator (DCM) is employed in a standard nondispersive arrangement. For coherent diffraction imaging it is advantageous to increase the available field of view by increasing the spatial coherence length (SCL) of a beam exiting such a DCM. Here, Talbot interferometry data together with ray-tracing simulations for a (+ − − +) four-reflection experimental arrangement are presented, wherein the first two reflections are in the DCM and the final fourth reflection is asymmetric at grazing exit. Analyses of the interferometry data combined with the simulations show that compared with the beam exiting the DCM a gain of 76% in the SCL was achieved, albeit with a factor of 20 reduction in flux density, which may not be a severe penalty at a synchrotron beamline. Previous efforts reported in the literature to increase the SCL that employed asymmetric crystal diffraction at grazing incidence are also discussed. A much reduced SCL is found presently in simulations wherein the same asymmetric crystal is set for grazing incidence instead of grazing exit. In addition, the present study is compared and contrasted with two other means of increasing the SCL. These are (i) focusing the beam onto an aperture to act as a secondary source, and (ii) allowing the beam to propagate in vacuum an additional distance along the beamline. Full Article text
spa Signal-to-noise and spatial resolution in in-line imaging. 1. Basic theory, numerical simulations and planar experimental images By journals.iucr.org Published On :: 2024-06-06 Signal-to-noise ratio and spatial resolution are quantitatively analysed in the context of in-line (propagation based) X-ray phase-contrast imaging. It is known that free-space propagation of a coherent X-ray beam from the imaged object to the detector plane, followed by phase retrieval in accordance with Paganin's method, can increase the signal-to-noise in the resultant images without deteriorating the spatial resolution. This results in violation of the noise-resolution uncertainty principle and demonstrates `unreasonable' effectiveness of the method. On the other hand, when the process of free-space propagation is performed in software, using the detected intensity distribution in the object plane, it cannot reproduce the same effectiveness, due to the amplification of photon shot noise. Here, it is shown that the performance of Paganin's method is determined by just two dimensionless parameters: the Fresnel number and the ratio of the real decrement to the imaginary part of the refractive index of the imaged object. The relevant theoretical analysis is performed first, followed by computer simulations and then by a brief test using experimental images collected at a synchrotron beamline. More extensive experimental tests will be presented in the second part of this paper. Full Article text
spa Investigating the missing-wedge problem in small-angle X-ray scattering tensor tomography across real and reciprocal space By journals.iucr.org Published On :: 2024-08-28 Small-angle-scattering tensor tomography is a technique for studying anisotropic nanostructures of millimetre-sized samples in a volume-resolved manner. It requires the acquisition of data through repeated tomographic rotations about an axis which is subjected to a series of tilts. The tilt that can be achieved with a typical setup is geometrically constrained, which leads to limits in the set of directions from which the different parts of the reciprocal space map can be probed. Here, we characterize the impact of this limitation on reconstructions in terms of the missing wedge problem of tomography, by treating the problem of tensor tomography as the reconstruction of a three-dimensional field of functions on the unit sphere, represented by a grid of Gaussian radial basis functions. We then devise an acquisition scheme to obtain complete data by remounting the sample, which we apply to a sample of human trabecular bone. Performing tensor tomographic reconstructions of limited data sets as well as the complete data set, we further investigate and validate the missing wedge problem by investigating reconstruction errors due to data incompleteness across both real and reciprocal space. Finally, we carry out an analysis of orientations and derived scalar quantities, to quantify the impact of this missing wedge problem on a typical tensor tomographic analysis. We conclude that the effects of data incompleteness are consistent with the predicted impact of the missing wedge problem, and that the impact on tensor tomographic analysis is appreciable but limited, especially if precautions are taken. In particular, there is only limited impact on the means and relative anisotropies of the reconstructed reciprocal space maps. Full Article text
spa A new dual-thickness semi-transparent beamstop for small-angle X-ray scattering By journals.iucr.org Published On :: 2024-08-25 An innovative dual-thickness semi-transparent beamstop designed to enhance the performance of small-angle X-ray scattering (SAXS) experiments is introduced. This design integrates two absorbers of differing thicknesses side by side into a single attenuator, known as a beamstop. Instead of completely stopping the direct beam, it attenuates it, allowing the SAXS detector to measure the transmitted beam through the sample. This approach achieves true synchronization in measuring both scattered and transmitted signals and effectively eliminates higher-order harmonic contributions when determining the transmission light intensity through the sample. This facilitates and optimizes signal detection and background subtraction. This contribution details the theoretical basis and practical implementation of this solution at the SAXS station on the 1W2A beamline at the Beijing Synchrotron Radiation Facility. It also anticipates its application at other SAXS stations, including that at the forthcoming High Energy Photon Source, providing an effective solution for high-precision SAXS experiments. Full Article text
spa Structure determination using high-order spatial correlations in single-particle X-ray scattering By journals.iucr.org Published On :: 2024-01-01 Single-particle imaging using X-ray free-electron lasers (XFELs) is a promising technique for observing nanoscale biological samples under near-physiological conditions. However, as the sample's orientation in each diffraction pattern is unknown, advanced algorithms are required to reconstruct the 3D diffraction intensity volume and subsequently the sample's density model. While most approaches perform 3D reconstruction via determining the orientation of each diffraction pattern, a correlation-based approach utilizes the averaged spatial correlations of diffraction intensities over all patterns, making it well suited for processing experimental data with a poor signal-to-noise ratio of individual patterns. Here, a method is proposed to determine the 3D structure of a sample by analyzing the double, triple and quadruple spatial correlations in diffraction patterns. This ab initio method can reconstruct the basic shape of an irregular unsymmetric 3D sample without requiring any prior knowledge of the sample. The impact of background and noise on correlations is investigated and corrected to ensure the success of reconstruction under simulated experimental conditions. Additionally, the feasibility of using the correlation-based approach to process incomplete partial diffraction patterns is demonstrated. The proposed method is a variable addition to existing algorithms for 3D reconstruction and will further promote the development and adoption of XFEL single-particle imaging techniques. Full Article text
spa C-SPAM: an open-source time-resolved specimen vitrification device with light-activated molecules By journals.iucr.org Published On :: 2023-12-14 Molecular structures can be determined in vitro and in situ with cryo-electron microscopy (cryo-EM). Specimen preparation is a major obstacle in cryo-EM. Typical sample preparation is orders of magnitude slower than biological processes. Time-resolved cryo-EM (TR-cryo-EM) can capture short-lived states. Here, Cryo-EM sample preparation with light-activated molecules (C-SPAM) is presented, an open-source, photochemistry-coupled device for TR-cryo-EM that enables millisecond resolution and tunable timescales across broad biological applications. Full Article text
spa Quantum refinement in real and reciprocal space using the Phenix and ORCA software By journals.iucr.org Published On :: 2024-09-30 X-ray and neutron crystallography, as well as cryogenic electron microscopy (cryo-EM), are the most common methods to obtain atomic structures of biological macromolecules. A feature they all have in common is that, at typical resolutions, the experimental data need to be supplemented by empirical restraints, ensuring that the final structure is chemically reasonable. The restraints are accurate for amino acids and nucleic acids, but often less accurate for substrates, inhibitors, small-molecule ligands and metal sites, for which experimental data are scarce or empirical potentials are harder to formulate. This can be solved using quantum mechanical calculations for a small but interesting part of the structure. Such an approach, called quantum refinement, has been shown to improve structures locally, allow the determination of the protonation and oxidation states of ligands and metals, and discriminate between different interpretations of the structure. Here, we present a new implementation of quantum refinement interfacing the widely used structure-refinement software Phenix and the freely available quantum mechanical software ORCA. Through application to manganese superoxide dismutase and V- and Fe-nitrogenase, we show that the approach works effectively for X-ray and neutron crystal structures, that old results can be reproduced and structural discrimination can be performed. We discuss how the weight factor between the experimental data and the empirical restraints should be selected and how quantum mechanical quality measures such as strain energies should be calculated. We also present an application of quantum refinement to cryo-EM data for particulate methane monooxygenase and show that this may be the method of choice for metal sites in such structures because no accurate empirical restraints are currently available for metals. Full Article text
spa Magnetic space groups versus representation analysis in the investigation of magnetic structures: the happy end of a strained relationship By journals.iucr.org Published On :: 2024-09-10 In recent decades, sustained theoretical and software developments have clearly established that representation analysis and magnetic symmetry groups are complementary concepts that should be used together in the investigation and description of magnetic structures. Historically, they were considered alternative approaches, but currently, magnetic space groups and magnetic superspace groups can be routinely used together with representation analysis, aided by state-of-the-art software tools. After exploring the historical antagonism between these two approaches, we emphasize the significant advancements made in understanding and formally describing magnetic structures by embracing their combined use. Full Article text
spa Visualizing the fibre texture of satin spar using laboratory 2D X-ray diffraction By journals.iucr.org Published On :: 2024-02-12 The suitability of point focus X-ray beam and area detector techniques for the determination of the uniaxial symmetry axis (fibre texture) of the natural mineral satin spar is demonstrated. Among the various diffraction techniques used in this report, including powder diffraction, 2D pole figures, rocking curves looped on φ and 2D X-ray diffraction, a single simple symmetric 2D scan collecting the reciprocal plane perpendicular to the apparent fibre axis provided sufficient information to determine the crystallographic orientation of the fibre axis. A geometrical explanation of the `wing' feature formed by diffraction spots from the fibre-textured satin spar in 2D scans is provided. The technique of wide-range reciprocal space mapping restores the `wing' featured diffraction spots on the 2D detector back to reciprocal space layers, revealing the nature of the fibre-textured samples. Full Article text
spa The multi-slit very small angle neutron scattering instrument at the China Spallation Neutron Source By journals.iucr.org Published On :: 2024-03-21 A multi-slit very small angle neutron scattering (MS-VSANS) instrument has been finally accepted at the China Spallation Neutron Source (CSNS). It is the first spallation neutron source based VSANS instrument. MS-VSANS has a good signal-to-noise ratio and can cover a wide scattering vector magnitude range from 0.00028 to 1.4 Å−1. In its primary flight path, a combined curved multichannel beam bender and sections of rotary exchange drums are installed to minimize the background downstream of the instrument. An exchangeable multi-slit beam focusing system is integrated into the primary flight path, enabling access to a minimum scattering vector magnitude of 0.00028 Å−1. MS-VSANS has three modes, namely conventional SANS, polarizing SANS and VSANS modes. In the SANS mode, three motorized high-efficiency 3He tube detectors inside the detector tank cover scattering angles from 0.12 to 35° simultaneously. In the polarizing SANS mode, a double-V cavity provides highly polarized neutrons and a high-efficiency 3He polarization analyser allows full polarization analysis. In the VSANS mode, an innovative high-resolution gas electron multiplier detector covers scattering angles from 0.016 to 0.447°. The absolute scattering intensities of a selection of standard samples are obtained using the direct-beam technique; the effectiveness of this method is verified by testing the standard samples and comparing the results with those from a benchmark instrument. The MS-VSANS instrument is designed to be flexible and versatile and all the design goals have been achieved. Full Article text
spa Accurate space-group prediction from composition By journals.iucr.org Published On :: 2024-06-18 Predicting crystal symmetry simply from chemical composition has remained challenging. Several machine-learning approaches can be employed, but the predictive value of popular crystallographic databases is relatively modest due to the paucity of data and uneven distribution across the 230 space groups. In this work, virtually all crystallographic information available to science has been compiled and used to train and test multiple machine-learning models. Composition-driven random-forest classification relying on a large set of descriptors showed the best performance. The predictive models for crystal system, Bravais lattice, point group and space group of inorganic compounds are made publicly available as easy-to-use software downloadable from https://gitlab.com/vishsoft/cosy. Full Article text
spa Synchrotron CT dosimetry for wiggler operation at reduced magnetic field and spatial modulation with bow tie filters By journals.iucr.org Published On :: 2024-10-22 The Australian Synchrotron Imaging and Medical Beamline (IMBL) uses a superconducting multipole wiggler (SCMPW) source, dual crystal Laue monochromator and 135 m propagation distance to enable imaging and computed tomography (CT) studies of large samples with mono-energetic radiation. This study aimed to quantify two methods for CT dose reduction: wiggler source operation at reduced magnetic field strength, and beam modulation with spatial filters placed upstream from the sample. Transmission measurements with copper were used to indirectly quantify the influence of third harmonic radiation. Operation at lower wiggler magnetic field strength reduces dose rates by an order of magnitude, and suppresses the influence of harmonic radiation, which is of significance near 30 keV. Beam shaping filters modulate the incident beam profile for near constant transmitted signal, and offer protection to radio-sensitive surface organs: the eye lens, thyroid and female breast. Their effect is to reduce the peripheral dose and the dose to the scanned volume by about 10% for biological samples of 35–50 mm diameter and by 20–30% for samples of up to 160 mm diameter. CT dosimetry results are presented as in-air measurements that are specific to the IMBL, and as ratios to in-air measurements that may be applied to other beamlines. As CT dose calculators for small animals are yet to be developed, results presented here and in a previous study may be used to estimate absorbed dose to organs near the surface and the isocentre. Full Article text
spa Satispay raises EUR 60 million to further drive its service expansion By thepaypers.com Published On :: Mon, 11 Nov 2024 14:27:00 +0100 Italy-based unicorn Satispay has announced... Full Article
spa Director Edgar Wright On His New Documentary ‘The Sparks Brothers’ And Why The Musicians Deserve To Be LA Rock Royalty By www.scpr.org Published On :: Fri, 18 Jun 2021 08:48:35 -0700 Edgar Wright attends the 55th Annual International Cinematographers Guild Publicists Awards at The Beverly Hilton Hotel on March 2, 2018 in Beverly Hills, California.; Credit: Tommaso Boddi/Getty Images FilmWeekThe joke about Sparks — if you’ve even heard of them — is that it’s the best British band to come out of America. That confusion is why Edgar Wright, the director of “Baby Driver” and “Shaun of the Dead,” wanted to make his first documentary about the group, headed by brothers Ron and Russell Mael. Quite simply, Wright was tired of explaining who the band was and why he loves them. His documentary, called “The Sparks Brothers,” premiered at this year’s Sundance Film Festival. John Horn talked with Wright after its January premiere about his personal connection to the band, how he connected with the brother, the editing process of the documentary and more. The film is in theaters now. With guest host John Horn Guest: Edgar Wright, director of the new documentary “The Sparks Brothers;” he tweets @edgarwright This content is from Southern California Public Radio. View the original story at SCPR.org. Full Article
spa Testing Finds 'Positive' Results for Base Metal Recoveries in Spain By www.streetwisereports.com Published On :: Tue, 05 Nov 2024 00:00:00 PST Emerita Resources Corp. (EMO:TSX.V; EMOTF:OTCQB; LLJA:FSE) announces results from a metallurgical testing program at its wholly-owned Iberian Belt West (IBW) project in Spain. Read why one expert says the company is in "the right place to be." Full Article EMO:TSX.V; EMOTF:OTCQB; LLJA:FSE
spa Catawba Industrial Commons to create manufacturing, distribution and warehousing space for industries By www.catawbacountync.gov Published On :: Thu, 7 Apr 2011 10:22:00 EST RealtyAnalytix Advisors, LLC announces the introduction of Catawba Industrial Commons, a multi-tenant industrial campus offering the most attractive, affordable and functional manufacturing, distribution and warehousing space in the Greater Catawba County region. Full Article News Release FYI Please Choose
spa New Report Examines Implications of Growing Gap in Life Span by Income for Entitlement Programs By Published On :: Thu, 17 Sep 2015 05:00:00 GMT As the gap in life expectancy between the highest and lowest earners in the U.S. has widened over time, high earners have disproportionately received larger lifetime benefits from government programs such as Social Security and Medicare, says a new congressionally mandated report from the National Academies of Sciences, Engineering, and Medicine. Full Article
spa NASA Should Continue its Large Strategic Missions to Maintain United States’ Global Leadership in Space By Published On :: Thu, 24 Aug 2017 05:00:00 GMT NASA’s large strategic missions like the Hubble Space Telescope, the Curiosity rover on Mars, and the Terra Earth observation satellite are essential to maintaining the United States’ global leadership in space exploration and should continue to be a primary component of a balanced space science program that includes large, medium, and smaller missions, says a new report by the National Academies of Sciences, Engineering, and Medicine. Full Article
spa Consumer Access to Affordable Medicines Is a Public Health Imperative, Says New Report - Government Negotiation of Drug Prices, Prevention of ‘Pay-for-Delay’ Agreements, and Increased Financial Transparency Among Recommendations By Published On :: Thu, 30 Nov 2017 06:00:00 GMT Consumer access to effective and affordable medicines is an imperative for public health, social equity, and economic development, but this need is not being served adequately by the biopharmaceutical sector, says a new report from the National Academies of Sciences, Engineering, and Medicine. Full Article