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AbbVie invests in switchable CAR-T therapies for cancer

The drug company is partnering with Calibr to develop universal CAR T cells directed to different tumors via antibody switches




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Un patógeno recluta bacterias buenas en la piel para iniciar infecciones

Un estudio hace que los científicos se replanteen cómo se desarrollan las infecciones bacterianas




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The spies next door




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Exclusive: Jason Gillespie explains what makes Jasprit Bumrah and Pat Cummins so special, and why reverse swing will be key with Kookaburra ball




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‘It was pretty clear to us where CA’s priorities lie’: Pakistan coach Jason Gillespie on Cricket Australia promoting BGT ahead of ODI series against Pakistan





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Real Madrid 'set Arsenal transfer deadline for Pierre-Emerick Aubameyang deal'

Madrid are keen to sign the striker, who is out of contract at the end of next season and appears set to leave the club in pursuit of Champions League football, but want to seal a deal immediately.




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Studies point way to precision therapies for common class of genetic disorders

Two Princeton University studies are opening important new windows into understanding an untreatable group of common genetic disorders known as RASopathies that affect approximately one child out of 1,000 and are characterized by distinct facial features, developmental delays, cognitive impairment and heart problems. The findings could help point the way toward personalized precision therapies for these conditions.




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Updated: Unilever recalls Wall’s Mini Calippo multi-packs because they may contain small pieces of metal

Unilever is recalling Wall’s Mini Calippo (Orange and Lemon-Lime) multi-packs because they may contain small pieces of metal. The presence of metal makes this product unsafe to eat.




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News24.com | Pieter du Toit: Beyond Covid-19 lies turbulence, change and opportunity

South Africans must insist on innovative solutions and new policies to ensure that when the country emerges from this governance and economic crisis, it does so not only aware of the country’s weaknesses but also primed to effect the necessary changes, writes Pieter du Toit.




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Disease modifying therapies for relapsing multiple sclerosis




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Penn State Altoona announces spring 2020 faculty and staff award recipients

Penn State Altoona this spring recognized outstanding employee contributions with the 2020 faculty and staff awards.




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Pieces of the puzzle

A suitcase sermon illustration helped Fredi understand what God had in store for him through full-time ministry with OM.




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3,000 CBSE Schools Open Today For Evaluation Of Board Answer Copies

The Home Ministry has granted permission for opening of 3000 CBSE affiliated schools as assessment centres across India to facilitate evaluation of answer sheets of CBSE Board exams.




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BS-VI Honda SP125 First Ride Review | Better comfort & refinement in a peppier looking package

BS-VI Honda SP125 Review: Honda's second BS6 compliant two-wheeler not only is now more fuel-efficient and cleaner for the environment, but it also offers several new features. We rode it around the streets of Mumbai to find out more.




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Credit Suisse arm invests in Sapience Analytics

Credit Suisse Asset Management's NEXT Investors has invested an undisclosed amount in Indian software product company Sapience Analytics.




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Book Review: Stop Reading the News – A Manifesto for a Happier, Calmer and Wiser Life

A cautionary note on the heavy deluge of unnecessary knowledge that surrounds us.




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1 In 10 Americans Prefer Colonoscopies To PC Security





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Piers Morgan to 'dial down' the anger towards Meghan Markle, admitting he went 'too far'

Piers Morgan has been at outs with the newly-exited British royal family members Harry and Meghan Markle




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Hollywood Punks and Hippie Scientists: New VOD Movies to Stream This Weekend

How are musical Valley Girl remake, Clark Duke's Arkansas, and Spaceship Earth? Here are our reviews.




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How Network Science Surfaced 81 Potential COVID-19 Therapies

Researchers led by Albert-László Barabási used network-based models to discover existing drugs that might take on COVID-19




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UFC legend St-Pierre to be inducted into HOF

UFC legend Georges St-Pierre will be inducted to UFC's Hall of Fame, it was announced on Saturday.




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Piers Morgan admits his criticism of Meghan Markle has 'probably' gone 'a bit too far'

Piers Morgan has admitted that he had probably “taken things a bit too far” with his criticism of the Duchess of Sussex.The Good Morning Britain presenter has been a regular critic of Meghan and her husband, particularly after they announced their decision to step back from their roles as senior royals.





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Georges St-Pierre headed to the UFC Hall of Fame

Canadian Georges St-Pierre, who ruled the UFC welterweight division before putting a bow on a glittering career by winning the middleweight title in his final outing, is headed to the UFC Hall of Fame.




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Piers Morgan's wife reveals unexpected way he's recovering after COVID-19 test

Piers Morgan's wife Celia Walden has revealed that her husband is using his downtime to...




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Piers Morgan admits his criticism of Meghan Markle has 'probably' gone 'a bit too far'




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Coronavirus: Fifty million plastic pieces sifted from beach in lockdown

Artist Rob Arnold is spending his lockdown sifting 40 sacks of beach litter in Cornwall.





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Piers Morgan admits he has probably 'taken things a bit too far' with his criticism of Meghan Markle

The Good Morning Britain presenter has previously accused the Duchess of Sussex of having 'ditched' her own relatives and splitting her husband Prince Harry from the Royal Family.




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Qantas cleaners handled face masks, soiled nappies, dirty tissues without gloves, inspector found

SafeWork New South Wales has slapped Qantas with an improvement notice after observing cleaners handle used face masks, vomit, soiled nappies and dirty tissues without gloves or masks.




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Atletico Madrid 'set £20m price tag on Kieran Trippier' amid Premier League interest

The 29-year-old moved to the Wanda Metropolitano last summer having fallen out of favour in north London, with the La Liga side splashing £20million on the England international.




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Piers Morgan admits he has probably 'taken things a bit too far' with his criticism of Meghan Markle

The Good Morning Britain presenter has previously accused the Duchess of Sussex of having 'ditched' her own relatives and splitting her husband Prince Harry from the Royal Family.




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Piers Morgan slams Sam Smith for 'causing Brit Awards shake-up'

Piers Morgan has slammed Sam Smith for 'causing a Brit Awards shake-up' after it was revealed the 'best male' and 'best female' categories could be abolished.




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Kmart shopper use pie maker to create oozing rocky road pastry tarts with leftover Easter eggs

An Australian home cook has wowed foodies after using Kmart's popular pie maker to create oozing rocky road pastry tarts with leftover Easter eggs.




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Ralph Hasenhuttl hopeful skipper Pierre-Emile Hojbjerg will remain at Southampton

Southampton boss Ralph Hasenhuttl has expressed his hope that captain Pierre-Emile Hojbjerg signs a new deal with the club.




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PewDiePie wedding: YouTuber marries social media star Marzia Bisognin

Internet sensation PewDiePie married longterm girlfriend Marzia Bisognin in a lavish ceremony at London's Kew Gardens on Monday - eight years to the day since they met.




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Atletico Madrid 'set £20m price tag on Kieran Trippier' amid Premier League interest

The 29-year-old moved to the Wanda Metropolitano last summer having fallen out of favour in north London, with the La Liga side splashing £20million on the England international.




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Mouthpiece of change


The government's recent CR policy is considered a big leap forward in enabling people to participate in the mass media. The next five years may see some self-help groups, fisherfolk and farmer groups, in areas remote and near, bid for radio stations of their own. Malvika Kaul reports.




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3,000 CBSE Schools Open Today For Evaluation Of Board Answer Copies

The Home Ministry has granted permission for opening of 3000 CBSE affiliated schools as assessment centres across India to facilitate evaluation of answer sheets of CBSE Board exams.




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Latest TRP Ratings: Uttar Ramayan Tops The Chart; Doordarshan’s Mahabharat Occupies Second Place

The latest BARC/TRP ratings for the Week 17 (April 25-May 1, 2020) are here. The mythological shows are still ruling the TRP chart. Among the mythological shows, Doordarshan National's Uttar Ramayan is at the tops slot while DD Bharti's Mahabharat has




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New Mahindra Thar Spied Ahead Of India Launch: Testing Resumes As Lockdown Eased

The 2020 Mahindra Thar has been spotted testing ahead of its launch in India. Vehicle testing has resumed as the nation-wide lockdown has been eased in certain states across the country.




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Latest TRP Ratings: Uttar Ramayan Tops The Chart; Doordarshan’s Mahabharat Occupies Second Place

The latest BARC/TRP ratings for the Week 17 (April 25-May 1, 2020) are here. The mythological shows are still ruling the TRP chart. Among the mythological shows, Doordarshan National's Uttar Ramayan is at the tops slot while DD Bharti's Mahabharat has




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The papers of Joseph Henry / Editor: Nathan Reingold. Assistant editors: Stuart Pierson and Arthur P. Molella with the assistance of James M. Hobbins and John R. Kerwood

Archives, Room Use Only - Q143.H6.A2 1972




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The A.B.C. of wireless telegraphy: a plain treatise on Hertzian wave signaling, embracing theory, methods of operation, and how to build various pieces of the apparatus employed / by Edward Trevert [pseud.]

Archives, Room Use Only - TK5741.T74 1902




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Hubble sees fragile comet break into dozens of pieces




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Only 2% of Covid-19 beds occupied in Karnataka

Karnataka’s efforts to slow the spread of coronavirus have ensured that healthcare systems are not overwhelmed with cases. This is evident from the low bed occupancy in dedicated Covid-19 hospitals. Ninety-eight per cent of the beds earmarked for coronavirus patients across the state are vacant.




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Welcome indicator: Only 2% of Covid-19 beds occupied in Karnataka | Bengaluru News - Times of India

Welcome indicator: Only 2% of Covid-19 beds occupied in Karnataka | Bengaluru News - Times of India




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Identifying dynamic, partially occupied residues using anomalous scattering

Although often presented as taking single `snapshots' of the conformation of a protein, X-ray crystallography provides an averaged structure over time and space within the crystal. The important but difficult task of characterizing structural ensembles in crystals is typically limited to small conformational changes, such as multiple side-chain conformations. A crystallographic method was recently introduced that utilizes residual electron and anomalous density (READ) to characterize structural ensembles encompassing large-scale structural changes. Key to this method is an ability to accurately measure anomalous signals and distinguish them from noise or other anomalous scatterers. This report presents an optimized data-collection and analysis strategy for partially occupied iodine anomalous signals. Using the long-wavelength-optimized beamline I23 at Diamond Light Source, the ability to accurately distinguish the positions of anomalous scatterers with occupancies as low as ∼12% is demonstrated. The number and positions of these anomalous scatterers are consistent with previous biophysical, kinetic and structural data that suggest that the protein Im7 binds to the chaperone Spy in multiple partially occupied conformations. Finally, READ selections demonstrate that re-measured data using the new protocols are consistent with the previously characterized structural ensemble of the chaperone Spy with its client Im7. This study shows that a long-wavelength beamline results in easily validated anomalous signals that are strong enough to be used to detect and characterize highly disordered sections of crystal structures.




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Comparative study of the around-Fermi electronic structure of 5d metals and metal-oxides by means of high-resolution X-ray emission and absorption spectroscopies

The composition of occupied and unoccupied electronic states in the vicinity of Fermi energies is vital for all materials and relates to their physical, chemical and mechanical properties. This work demonstrates how the combination of resonant and non-resonant X-ray emission spectroscopies supplemented with theoretical modelling allows for quantitative analysis of electronic states in 5d transition metal and metal-oxide materials. Application of X-rays provides element selectivity that, in combination with the penetrating properties of hard X-rays, allows determination of the composition of electronic states under working conditions, i.e. non-vacuum environment. Tungsten metal and tungsten oxide are evaluated to show the capability to simultaneously assess composition of around-band-gap electronic states as well as the character and magnitude of the crystal field splitting.