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Advances in genome editing: the technology of choice for precise and efficient β-thalassemia treatment




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Tanezumab improves difficult-to-treat OA




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BCR selection and affinity maturation in Peyer’s patch germinal centres




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Th22 cells are efficiently recruited in the gut by CCL28 as an alternative to CCL20 but do not compensate for the loss of Th17 cells in treated HIV-1-infected individuals




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Comparative efficacy of a hydroxyapatite and a fluoride toothpaste for prevention and remineralization of dental caries in children




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Nanopore sequencing and the Shasta toolkit enable efficient de novo assembly of eleven human genomes




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Safety and efficacy of chimeric antigen receptor T-cell therapy in relapsed/refractory multiple myeloma with renal impairment




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Extending therapeutic protein half-lives via fusion to affibodies with pH-dependent binding to neonatal Fc receptor

Fusing therapeutic proteins to affibodies with pH-dependent binding to neonatal Fc receptor could improve the proteins' half-lives.




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Compound LM9, a novel MyD88 inhibitor, efficiently mitigates inflammatory responses and fibrosis in obesity-induced cardiomyopathy




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Efficient generation of mouse models with the prime editing system




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The anti-influenza virus drug, arbidol is an efficient inhibitor of SARS-CoV-2 in vitro




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MEI Affiliate Books

Newly published books by MEI affiliate scholars. 




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Using physiologically-based pharmacokinetic modeling to assess the efficacy of glove materials in reducing internal doses and potential hazards of N-methylpyrrolidone during paint stripping




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Over 1 lakh migrants to return to UP on 114 trains by Saturday night: Official

Over 1 lakh migrant workers from Uttar Pradesh stranded in different parts of the country following the coronavirus-induced lockdown will return to the state by Saturday night on 114 trains, a senior government official said.




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Some Trump Officials Take Harder Actions on China During Pandemic

Since the coronavirus spread from a metropolis on the Yangtze River across the globe, hard-liners in both Washington and Beijing have accelerated efforts to decouple elements of the relationship.




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MEI Affiliate Books

Newly published books by MEI affiliate scholars. 




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MEI Affiliate Books

Newly published books by MEI affiliate scholars. 




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Some Trump Officials Take Harder Actions on China During Pandemic

Since the coronavirus spread from a metropolis on the Yangtze River across the globe, hard-liners in both Washington and Beijing have accelerated efforts to decouple elements of the relationship.




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Some Trump Officials Take Harder Actions on China During Pandemic

Since the coronavirus spread from a metropolis on the Yangtze River across the globe, hard-liners in both Washington and Beijing have accelerated efforts to decouple elements of the relationship.




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Massa frustrated at Q2 traffic

Felipe Massa admitted to being a little frustrated at qualifying sixth on the grid after being held up by Lewis Hamilton towards the end of Q2, ruining one of his flying laps




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MEI Affiliate Books

Newly published books by MEI affiliate scholars. 





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MEI Affiliate Books

Newly published books by MEI affiliate scholars. 




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MEI Affiliate Books

Newly published books by MEI affiliate scholars. 




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Coronavirus has shown us a world without traffic. Can we sustain it?

There are few silver linings to the COVID-19 pandemic, but free-flowing traffic is certainly one of them. For the essential workers who still must commute each day, driving to work has suddenly become much easier. The same applies to the trucks delivering our surging e-commerce orders. Removing so many cars from the roads has even…

       




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Massa bemoans difficult race

Felipe Massa complained about a lack of grip from his Ferrari after finishing a disappointing sixth in the Spanish Grand Prix




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MEI Affiliate Books

Newly published books by MEI affiliate scholars. 




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Some Trump Officials Take Harder Actions on China During Pandemic

Since the coronavirus spread from a metropolis on the Yangtze River across the globe, hard-liners in both Washington and Beijing have accelerated efforts to decouple elements of the relationship.




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MEI Affiliate Books

Newly published books by MEI affiliate scholars. 




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MEI Affiliate Books

Newly published books by MEI affiliate scholars. 




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'We have to make difficult decisions' - Horner

Red Bull boss Christian Horner denied suggestions Mark Webber is being regarded as the team's second driver




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MEI Affiliate Books

Newly published books by MEI affiliate scholars. 




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The Economic Gains of Cloud Computing: An Address by Federal Chief Information Officer Vivek Kundra

Event Information

April 7, 2010
9:00 AM - 11:00 AM EDT

Falk Auditorium
The Brookings Institution
1775 Massachusetts Ave., NW
Washington, DC

Register for the Event

Cloud computing services over the Internet have the potential to spur a significant increase in government efficiency and decrease technology costs, as well as to create incentives and online platforms for innovation. Adoption of cloud computing technologies could lead to new, efficient ways of governing.

On April 7, the Brookings Institution hosted a policy forum that examines the economic benefits of cloud computing for local, state, and federal government. Federal Chief Information Officer Vivek Kundra delivered a keynote address on the role of the government in developing and promoting cloud computing. Brookings Vice President Darrell West moderated a panel of experts and detailed the findings in his paper, "Saving Money through Cloud Computing," which analyzes its governmental cost-savings potential.

After the program, panelists took audience questions.

Video

Audio

Transcript

Event Materials

     
 
 




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This US-China downturn may be difficult for Taiwan

Many Taiwan policymakers hold the view that U.S.-China tensions create favorable conditions for closer U.S.-Taiwan relations. As the thinking goes, the less beholden Washington is to maintaining stable relations with Beijing, the more it will be willing to show support for its democratic friends in Taiwan. In the coming months, this proposition may be tested.…

       




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A Chicago-Area Retrofit Strategy: Coordinating Energy Efficiency Region-Wide

The Center for Neighborhood Technology, a Chicago-area nonprofit promoting urban sustainability, has a long-run vision of a Chicagoland building energy-efficiency system, which, if started up quickly, would help to effectively deploy relevant stimulus dollars in the near-term. Its activities focus on ramping up existing weatherization and retrofit programs in the short-term to take best advantage of current stimulus dollars while at the same time building the institutional capacity to launch and sustain a new regional initiative aimed at coordinating energy efficiency information, financing, and service delivery for the seven-county region over the long-term.

The Center for Neighborhood Technology (CNT) is using ARRA and other resources to work toward a long-run vision of a sustainable regional energy efficiency system. CNT envisions a centrally-coordinated initiative— either through a new stand-alone entity or a formalized network—to manage the financing, marketing, performance monitoring and certification, information provision, supply chain development, and customer assistance required to efficiently scale up the delivery of retrofit services for all types of buildings across the Chicago region.

Downloads

      
 
 




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How office design can catalyze an innovative culture

Which of these two photos, A or B, reveals an organizational culture that is controlling? As institutions, large companies, and small firms dedicate tremendous resources to strengthen their innovation potential, many fail to realize that their office design can be a key building block or a barrier for achieving their goals.  The Anne T. and […]

      
 
 




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Metro Philadelphia’s Energy Efficiency Strategy: Promoting Regionalism to Advance Recovery

Bringing together the five counties of Southeastern Pennsylvania, the nonprofit Metropolitan Caucus, a new regional consortium there, is promoting a joint regional application for ARRA’s competitive Energy Efficiency and Conservation Block Grant dollars. Its four-part proposal, which will add and refine partners and programs over time, draws on the collaboration of multiple regional institutions to establish and operate a loan fund for green building and retrofits; support clean energy technology deployment; assist local governments with energy efficiency plans; and measure the energy performance of public facilities.

The newly created Metropolitan Caucus of southeastern Pennsylvania is leading the bold new regional energy efficiency strategy targeting for the competitive Energy Efficiency and Conservation Block Grants (EECBG) in the American Recovery and Reinvestment Act (ARRA). Unprecedented for the region, the Metropolitan Caucus has brought together five area counties—Bucks, Chester, Delaware, Montgomery, and Philadelphia—to make the most of the stimulus opportunity by coordinating their plans, goals, and assets to achieve maximum regional benefit. Their proposed joint EECBG competitive application for roughly $35 million calls for financing construction and retrofits, supporting clean energy companies, measuring building energy performance, and assisting local governments in implementing various sustainability solutions. To carry out each of these activities, the caucus intends to engage in broad cross-sector collaboration to leverage the strengths and unique assets of regional educational institutions, key nonprofits, and planning agencies.

Downloads

     
 
 




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The Development Finance Corporation confirms the new chief development officer—what’s the role?

The Board of the U.S. International Development Finance Corporation (DFC) just confirmed Andrew Herscowitz to the position of chief development officer (CDO). A career USAID foreign service officer, Andrew has spent the past seven years directing Power Africa. It is hard to think of a more relevant background for this position—two decades with USAID, extensive…

       




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Private capital flows, official development assistance, and remittances to Africa: Who gets what?


Strong Growth and Changing Composition 

External financial flows to sub-Saharan Africa (defined as the sum of gross private capital flows, official development assistance (ODA), and remittances to the region) have not only grown rapidly since 1990, but their composition has also changed significantly. The volume of external flows to the region increased from $20 billion in 1990 to above $120 billion in 2012. Most of this increase in external flows to sub-Saharan Africa can be attributed to the increase in private capital flows and the growth of remittances, especially since 2005 (see Figure 1).

Figure 1. Sub-Saharan Africa: External Flows (1990-2012, in USD billions)

As also displayed in Figure 1, in 1990 the composition of external flows to sub-Saharan Africa was about 62 percent ODA, 31 percent gross inflows from the private sector, and about 7 percent remittances. However, by 2012, ODA accounted for about 22 percent of external flows to Africa, a share comparable to that of remittances (24 percent) and less than half the share of gross private capital flows (54 percent). Also notably, in 1990, FDI flows were greater than ODA flows in only two countries (Liberia and Nigeria) in sub-Saharan Africa excluding South Africa, but 22 years later, 17 countries received more FDI than ODA in 2012—suggesting that sub-Saharan African countries are increasingly becoming less aid dependent (see Figure 2).

Figure 2. Sub-Saharan Africa: Number of Countries Where FDI is Greater than ODA (1990-2012)

But to what extent have these changes in the scale and composition of external flows to sub-Saharan Africa equally benefited countries in the region? Did the rising tide lift all boats? Is aid really dying? Are all countries attracting private capital flows and benefiting from remittances to the same degree? Finally, how does external finance compare with domestic finance? 

The False Demise of ODA

A closer look at the data indicates that, clearly, ODA is not dead, though its role is changing. For instance, middle-income countries (MICs) are experiencing the sharpest decline in ODA as a share of total external flows to the region, while aid flows account for more than half of external flows in fragile as well as low-income countries (LICs) and resource-poor landlocked countries (see Figure 3 and Appendix).

Download the full paper »

Authors

      
 
 




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Ghosts of Resolutions Past: The G20 Agreement on Phasing Out Inefficient Fossil Fuel Subsidies


As much as the nostalgic might hate to admit it, a new year is coming up. And for climate change negotiators, 2015 is a big one: it’s the make-it-or-break it year for a serious, last-ditch effort at an international agreement to slow runaway climate change. 

A new year brings new, hopeful resolutions. Of course, just as ubiquitous are the pesky memories of past resolutions that one never quite accomplished.

Some resolutions fade, understandably. But failure is less forgivable when the repercussions include the increased exploration of fossil fuels at the expense of our warming world. To avoid the most destructive effects of climate change, we must keep two-thirds of existing fossil fuel reserves underground, instead of providing subsidies to dig them up.

One group not living up to its resolution: the G20 members —19 countries and the European Union that make up 85% of global GDP. At the 2009 G20 summit in Pittsburgh, the group agreed to “rationalize and phase out over the medium term inefficient fossil fuel subsidies that encourage wasteful consumption.” At the 2013 summit in St. Petersburg, they reaffirmed this resolution. Yet that same year, these countries funneled $88 billion into exploring new reserves of oil, gas, and coal.

Another resolution abandoned.

This year’s G20 summit will convene in Brisbane, Australia (November 15th - 16th) — a perfect opportunity to commiserate about the backsliding on the agreement and to develop a new approach that includes some means of holding each other accountable. So how can the G20 follow through on its laudable and necessary pledge?

1. Get help from the experts.

A new report by the Overseas Development Institute and Oil Change International criticizes the G20 for “marry[ing] bad economics with potentially disastrous consequences for climate change.” It points out that every dollar used to subsidize renewables generates twice as much investment as the dollar that subsidizes fossil fuels.

And the G20 can try harder to heed the doctor’s orders. This report outlines specific recommendations, including revamping tax codes to support low carbon development instead.

2. Set a timeline and stick to it.

National timelines for fossil fuel subsidy phase out would be different depending on the governmental structures and budgeting processes of individual countries. Also, countries can utilize the timeline of the incoming international climate treaty, by including a subsidy phase out as part of a mitigation plan to be measured and reported.

3. It’s easier with friends.

The G20 got it right that no one country should have to go it alone. Now it is time to strengthen its methodology for peer review of inefficient fossil fuel subsidies, and agree upon a transparent and consistent system for tracking and reporting.

That said, it can also be easier to cheat with friends. The new report tracks where investments from G20 state-owned energy companies are directed. As it turns out, G20 countries continue to fund each other’s fossil fuel exploration. Instead of cheating together on their own resolution, G20 members should leverage these relationships to advance investments in clean energy.  

4. Hold each other accountable.

The G20 is not the only group that has committed to phase out fossil fuel subsidies. The issue has received support from advocacy groups, religious leaders, and business constituencies alike. The public will be able to better hold leaders accountable if the G20 declares its commitment and progress loud and proud.

Moreover, G20 members and advocacy organizations can make the facts very clear: fossil fuel subsidies do not support the world’s poor, and the public ends up paying for the externalities they cause in pollution and public health. This accountability to addressing concerns of the people can help the G20 stand up to the fossil fuel industry.

5. If at first you don’t succeed…

True, phasing out fossil fuel subsidies is no piece of cake. There is no G20 standard definition of “inefficient subsidies” or timeline for the phase out. It also hasn’t helped that countries report their own data. They can even opt out of this unenforced commitment altogether. Yet the pledge is there, as is the urgency of the issue. New Year’s resolutions take more than just commitments — they take work. This week’s G20 Leaders Summit is a wonderful place to commit to phasing out fossil fuel subsidies. Again.

Authors

Image Source: © Francois Lenoir / Reuters
     
 
 




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The Development Finance Corporation confirms the new chief development officer—what’s the role?

The Board of the U.S. International Development Finance Corporation (DFC) just confirmed Andrew Herscowitz to the position of chief development officer (CDO). A career USAID foreign service officer, Andrew has spent the past seven years directing Power Africa. It is hard to think of a more relevant background for this position—two decades with USAID, extensive…

       




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2014 Brookings Blum Roundtable: Jump-Starting Inclusive Growth in the Most Difficult Environments


Event Information

August 7-9, 2014

Aspen, Colorado

The start of the 21st century has been an auspicious period for global economic development. In the 1990s, a mere 13 emerging economies succeeded in growing at a speed at least twice that of the OECD countries, enabling rapid convergence on Western living standards. By the first decade of the 2000s, this number had mushroomed to 83. Accelerated rates of economic growth lay behind many of the recent success stories in global development, not least the fulfilment of the first Millennium Development Goal to halve the global poverty rate, five years ahead of the 2015 deadline. Yet in a number of places, growth has failed to take off, has undergone periodic reversals, or has benefited a few while leaving the majority short-changed.

On August 7-9, 2014, Brookings Global Economy and Development is hosting the eleventh annual Brookings Blum Roundtable on Global Poverty in Aspen, Colorado. This year’s roundtable theme, “Jump-Starting Inclusive Growth in the Most Difficult Environment,” brings together global leaders, entrepreneurs, practitioners, and public intellectuals to discuss what strategies exist for promoting inclusive economic growth in settings where standard prescriptions are not feasible or sufficient as well as what the comparative advantages are of different actors seeking to improve the prospects for inclusive growth and how can they most effectively collaborate with each other to increase their impact. 

This event is closed, but you can follow along on Twitter using #Blum2014.



Roundtable Agenda


Thursday, August 7, 2014

Welcome - 3:30-4:00 p.m.:

  • Strobe Talbott, Brookings Institution

Opening Remarks:

Session I - 4:00-5:00 p.m.: How Can Multinationals Engage With Governments to Support Economic Development?

Multinational corporations are increasingly recognized as key partners for governments in development planning. Corporations are brought into discussions at various levels: around individual projects and their impact on affected localities; on sector performance, regulation and competition; and on country-level issues such as the business environment, infrastructure, jobs, and skills.

What motivations do multinationals have to participate in government engagement? Do discussions work better under formalized and multilateral structures, such as business councils, or on an ad-hoc bilateral basis? How does engagement differ in poor and weakly governed countries?    

Moderator:

Introductory Remarks:

  • Jane Nelson, Harvard University
  • Tara Nathan, MasterCard Worldwide
  • The Honorable Amara Konneh, Government of Liberia

Aspen Institute Madeleine K. Albright Global Development Dinner & Lecture - 7:00-9:30 p.m.:

The Aspen Institute Madeleine K. Albright Global Development Lecture recognizes an exceptional individual whose vision has provided breakthrough thinking to tackle the challenges of global development.

Featuring: 


Friday, August 8, 2014

Session II - 9:00 - 10:30 a.m.: Managing Risks in Conflict Settings

Ending extreme poverty over the next generation will require inclusive and sustained growth across the developing world. This is a particularly onerous challenge in fragile and conflict-affected states, which account for a growing share of the world’s poor. There is growing recognition that fast economic recovery, and the jobs that go with it, can serve to shore up peace agreements and help countries successfully transition beyond the immediate post-conflict phase.

What can be done to support investors and entrepreneurs weighing up the risks and opportunities of starting or expanding business in these settings? What risk-mitigating instruments and strategies work? How can corporations identify, foster and partner with local businesses to support job creation and private sector development?

Moderator:

Introductory Remarks:


Session III - 10:50-12:00 p.m.: Leap-Frogging Technologies

Weak legal and regulatory frameworks, crime and corruption, deficient infrastructure, and lack of access to finance are common constraints to many developing economies. New leap-frogging technologies offer poor countries the potential to overcome some of these challenges without the cost, capacity or good governance required from traditional solutions. Mobile technology, powered by nearly five billion mobile subscriptions worldwide, provides a platform through which to do business and expand financial services. Off-grid power and the internet offer other examples of how weak infrastructure and missing public goods can be circumvented. Special economic zones and charter cities offer the possibility of forging oases where economic conditions are favorable.

On what conditions, if any, does successful leap-frogging depend? What type of financing instruments do innovators look for when designing and marketing such technologies? What are the sources of growth in low-income countries and what can they tell us about new growth strategies?

Moderator:

Introductory Remarks:


Session IV - 2:00-3:30 p.m.: Delivering Government Partnerships

With President Obama’s June 2013 announcement of Power Africa, the U.S. government is demonstrating its new vision for development built on public-private partnerships. Historically, such partnerships have a mixed tracked record.

How can we make sure that Power Africa, Feed the Future, and similar partnerships deliver to their full potential? What have we learned about structuring effective government-business-donor cooperation?

Moderator:

  • Dana Hyde, Millennium Challenge Corporation

Introductory Remarks:


Saturday, August 9, 2014

Session V - 9:00-10:30 a.m.: Unlocking Big Deals

Massive infrastructure gaps in the energy, transport, information and communications technology, water, and urban sectors threaten the long-term competitiveness and prospects for sustainable development across many countries. This realization has spurred interest from countries, donors, regional groups and development finance institutions to devise new ways of overcoming constraints to mega-investment deals, particularly agreements that are cross-border in scope. Identified constraints include a shortage of early-stage project development finance; skilled legal, technology and financial experts; and instruments to attract additional capital from external players like institutional investors and international investment banks.

How can constraints to big deals be overcome, and what are the ingredients that allow for enduring partnerships to deliver on these projects? Are dedicated pools of financing needed to unlock these deals?

Moderator:

Introductory Remarks:

Session VI - 10:50-12:20 p.m.: Where Can Enclave Projects Take Us?

Recent discoveries of natural resource wealth in East Africa offer the promise of supercharged growth in one of the world’s poorest regions. A critical challenge is to leverage the capital, skills and knowledge generated from enclave growth to support nascent other industries.

How can corporations, government, and NGOs support structural transformation away from enclave activities? What sorts of industries present the most feasible small steps away from extractive sector activities?

Moderator:

  • Smita Singh, Independent 
Introductory Remarks:

Closing Remarks:

Event Materials

      
 
 




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Coronavirus has shown us a world without traffic. Can we sustain it?

There are few silver linings to the COVID-19 pandemic, but free-flowing traffic is certainly one of them. For the essential workers who still must commute each day, driving to work has suddenly become much easier. The same applies to the trucks delivering our surging e-commerce orders. Removing so many cars from the roads has even…

       




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Faster, more efficient innovation through better evidence on real-world safety and effectiveness


Many proposals to accelerate and improve medical product innovation and regulation focus on reforming the product development and regulatory review processes that occur before drugs and devices get to market. While important, such proposals alone do not fully recognize the broader opportunities that exist to learn more about the safety and effectiveness of drugs and devices after approval. As drugs and devices begin to be used in larger and more diverse populations and in more personalized clinical combinations, evidence from real-world use during routine patient care is increasingly important for accelerating innovation and improving regulation.

First, further evidence development from medical product use in large populations can allow providers to better target and treat individuals, precisely matching the right drug or device to the right patients. As genomic sequencing and other diagnostic technologies continue to improve, postmarket evidence development is critical to assessing the full range of genomic subtypes, comorbidities, patient characteristics and preferences, and other factors that may significantly affect the safety and effectiveness of drugs and devices. This information is often not available or population sizes are inadequate to characterize such subgroup differences in premarket randomized controlled trials.

Second, improved processes for generating postmarket data on medical products are necessary for fully realizing the intended effect of premarket reforms that expedite regulatory approval. The absence of a reliable postmarket system to follow up on potential safety or effectiveness issues means that potential signals or concerns must instead be addressed through additional premarket studies or through one-off postmarket evaluations that are more costly, slower, and likely to be less definitive than would be possible through a better-established infrastructure. As a result, the absence of better systems for generating postmarket evidence creates a barrier to more extensive use of premarket reforms to promote innovation.

These issues can be addressed through initiatives that combine targeted premarket reforms with postmarket steps to enhance innovation and improve evidence on safety and effectiveness throughout the life cycle of a drug or device. The ability to routinely capture clinically relevant electronic health data within our health care ecosystem is improving, increasingly allowing electronic health records, payer claims data, patient-reported data, and other relevant data to be leveraged for further research and innovation in care. Recent legislative proposals released by the House of Representatives’ 21st Century Cures effort acknowledge and seek to build on this progress in order to improve medical product research, development, and use. The initial Cures discussion draft included provisions for better, more systematic reporting of and access to clinical trials data; for increased access to Medicare claims data for research; and for FDA to promulgate guidance on the sources, analysis, and potential use of so-called Real World Evidence. These are potentially useful proposals that could contribute valuable data and methods to advancing the development of better treatments.

What remains a gap in the Cures proposals, however, is a more systematic approach to improving the availability of postmarket evidence. Such a systematic approach is possible now. Biomedical researchers and health care plans and providers are doing more to collect and analyze clinical and outcomes data. Multiple independent efforts – including the U.S. Food and Drug Administration’s Sentinel Initiative for active postmarket drug safety surveillance, the Patient-Centered Outcomes Research Institute’s PCORnet for clinical effectiveness studies, the Medical Device Epidemiology Network (MDEpiNet) for developing better methods and medical device registries for medical device surveillance and a number of dedicated, product-specific outcomes registries – have demonstrated the potential for large-scale, systematic postmarket data collection. Building on these efforts could provide unprecedented evidence on how medical products perform in the real-world and on the course of underlying diseases that they are designed to treat, while still protecting patient privacy and confidentiality.

These and other postmarket data systems now hold the potential to contribute to public-private collaboration for improved population-based evidence on medical products on a wider scale. Action in the Cures initiative to unlock this potential will enable the legislation to achieve its intended effect of promoting quicker, more efficient development of effective, personalized treatments and cures.

What follows is a set of both short- and long-term proposals that would bolster the current systems for postmarket evidence development, create new mechanisms for generating postmarket data, and enable individual initiatives on evidence development to work together as part of a broad push toward a truly learning health care system.

Downloads

      




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Amidst unimpressive official jobs report for May, alternative measures make little difference


May’s jobs gains, released this morning, show that only 38,000 new jobs were added this May, down from an average of 178,000 over the first four months of the year, and the least new jobs added since September 2010.

This year’s monthly job gains and losses can indicate how the economy is doing once they are corrected to account for the pattern we already expect in a process called seasonal adjustment. The approach for this seasonal adjustment that is presently used by the Bureau of Labor Statistics (BLS) puts very heavy weight on the current and last two years of data in assessing what are the typical patterns for each month.

In my paper “Unseasonal Seasonals?” I argue that a longer window should be used to estimate seasonal effects. I found that using a different seasonal filter, known as the 3x9 filter, produces better results and more accurate forecasts by emphasizing more years of data. The 3x9 filter spreads weight over the most recent six years in estimating seasonal patterns, which makes them more stable over time than in the current BLS seasonal adjustment method.

I calculate the month-over-month change in total nonfarm payrolls, seasonally adjusted by the 3x9 filter, for the most recent month. The corresponding data as published by the BLS are shown for comparison purposes. According to the alternative seasonal adjustment, the economy actually lost about 4,000 jobs in May (column Wright SA), compared to the official BLS total of 38,000 gained (column BLS Official).

In addition to seasonal effects, abnormal weather can also affect month-to-month fluctuations in job growth. In my paper “Weather-Adjusting Economic Data” I and my coauthor Michael Boldin implement a statistical methodology for adjusting employment data for the effects of deviations in weather from seasonal norms. This is distinct from seasonal adjustment, which only controls for the normal variation in weather across the year. We use several indicators of weather, including temperature and snowfall.

We calculate that weather in May had a negligible effect on employment, bringing up the total by only 4,000 jobs (column Weather Effect). Our weather-adjusted total, therefore, is 34,000 jobs added for May (column Boldin-Wright SWA). This is not surprising, given that weather in May was in line with seasonal norms.

Unfortunately, neither the alternative seasonal adjustment, nor the weather adjustment, makes todays jobs report any more hopeful. They make little difference and, if anything, make the picture more gloomy.

a. Applies a longer window estimate of seasonal effects (see Wright 2013).
b. Includes seasonal and weather adjustments, where seasonal adjustments are estimated using the BLS window specifications (see Boldin & Wright 2015). The incremental weather effect in the last column is the BLS official number less the SWA number.

Authors

  • Jonathan Wright
Image Source: © Toru Hanai / Reuters
     
 
 




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What coronavirus means for online fraud, forced sex, drug smuggling, and wildlife trafficking

Possibly emerging as a result of wildlife trafficking and the consumption of wild animal meat, COVID-19 is influencing crime and illicit economies around the world. Some of the immediate effects are likely to be ephemeral; others will take longer to emerge but are likely to be lasting. How is the COVID-19 outbreak affecting criminal groups,…

       




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COVID-19 is hitting the nation’s largest metros the hardest, making a “restart” of the economy more difficult

The coronavirus pandemic has thrown America into a coast-to-coast lockdown, spurring ubiquitous economic impacts. Data on smartphone movement indicate that virtually all regions of the nation are practicing some degree of social distancing, resulting in less foot traffic and sales for businesses. Meanwhile, last week’s release of unemployment insurance claims confirms that every state is seeing a significant…

       




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What coronavirus means for online fraud, forced sex, drug smuggling, and wildlife trafficking

Possibly emerging as a result of wildlife trafficking and the consumption of wild animal meat, COVID-19 is influencing crime and illicit economies around the world. Some of the immediate effects are likely to be ephemeral; others will take longer to emerge but are likely to be lasting. How is the COVID-19 outbreak affecting criminal groups,…

       




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Africa in the news: Nigeria establishes flexible exchange rate, Kenya reaffirms plan to close Dabaab refugee camp, and AfDB meetings focus on energy needs


Nigeria introduces dual exchange rate regime

On Tuesday, May 24, Nigerian Central Bank Governor Godwin Emefiele announced that the country will adopt a more flexible foreign exchange rate system in the near future. This move signals a major policy shift by Emefiele and President Muhammadu Buhari, who had until this point opposed calls to let the naira weaken. Many international oil-related currencies have depreciated against the dollar as oil prices began their decline in 2014. Nigeria, however, has held the naira at a peg of 197-199 per U.S. dollar since March 2015, depleting foreign reserves and deterring investors, who remain concerned about the repercussions of a potential naira devaluation. Following the announcement, Nigerian stocks jumped to a five-month high and bond prices rose in anticipation that a new flexible exchange rate regime would increase the supply of dollars and help attract foreign investors.

For now it remains unclear exactly what a more flexible system will entail for Nigeria, however, some experts suggest that the Central Bank may introduce a dual-rate system, which allows select importers in strategic industries to access foreign currency at the current fixed rate, while more generally foreign currency will be available at a weaker, market-related level. This new regime raises a number of questions, including how it will be governed and who will have access to foreign currency (and at what rate). On Wednesday, Nigeria’s parliament requested a briefing soon from Emefiele and Finance Minister Kemi Adeosun to provide additional clarity on the new system, although the date for such a meeting has not yet been set.

Kenya threatens to close the Dadaab refugee camp, the world’s largest

Earlier this month, Kenya announced plans to close the Dadaab refugee camp, located in northeast Kenya, amid security concerns. The move to close the camp has been widely criticized by international actors. United States State Department Press Relations Director Elizabeth Trudeau urged Kenya to “uphold its international obligations and not forcibly repatriate refugees.” The United Nations High Commissioner for Refugees stated that the closure of the refugee camp would have “devastating consequences.” Despite these concerns, this week, at the World Humanitarian Summit, Kenya stated that it will not go back on its decision and confirmed the closure of the refugee camps within a six-month period.

The camp houses 330,000 refugees, a majority of whom fled from conflict in their home country of Somalia. Kenya insists that the camp poses a threat to its national security, as it believes the camp is used to host and train extremists from Somalia’s Islamist group al-Shabab. Kenya also argued that the developed world, notably the United Kingdom, should host its fair share of African refugees. This is not the first time Kenya has threatened to close the refugee camp. After the Garissa University attacks last April, Kenya voiced its decision to close the refugee camps, although it did not follow through with the plan.

African Development Bank Meetings highlight energy needs and launch the 2016 African Economic Outlook

From May 23-27, Lusaka, Zambia hosted 5,000 delegates and participants for the 2016 Annual Meetings of the African Development Bank (AfDB), with the theme, “Energy and Climate Change.” Held in the wake of December’s COP21 climate agreement and in line with Sustainable Development Goals 7 (ensure access to affordable, reliable, sustainable and modern energy for all) and 13 (take urgent action to combat climate change and its impacts), the theme was timely and, as many speakers emphasized, urgent. Around 645 million people in Africa have no access to electricity, and only 16 percent are connected to an energy source. To that end, AfDB President Akinwumi Adesina outlined the bank’s ambitious aim: “Our goal is clear: universal access to energy for Africa within 10 years; Expand grid power by 160 gigawatts; Connect 130 million persons to grid power; Connect 75 million persons to off grid systems; And provide access to 150 million households to clean cooking energy."

As part of a push to transform Africa’s energy needs and uses, Rwandan President Paul Kagame joined Kenyan President Uhuru Kenyatta on a panel to support the AfDB’s “New Deal on Energy” that aims to deliver electricity to all Africans by 2025. Kenyatta specifically touted the potential of geothermal energy sources. Now, 40 percent of Kenya's power needs come from geothermal energy sources, he said, but there is still room for improvement—private businesses, which make up 30 percent of Kenya’s on-grid energy needs, have not made the switch yet.

As part of the meetings, the AfDB, the Organization for Economic Cooperation and Development (OECD), and United Nations Development Program (UNDP) also launched their annual African Economic Outlook, with the theme “Sustainable Cities and Structural Transformation.” In general, the report’s authors predict that the continent will maintain an average growth of 3.7 percent in 2016 before increasing to 4.5 percent in 2017, assuming commodity prices recover and the global economy improves.  However, the focus was on this year’s theme: urbanization. The authors provide an overview of urbanization trends and highlight that successful urban planning can discourage pollution and waste, slow climate change, support better social safety nets, enhance service delivery, and attract investment, among other benefits.

For more on urbanization in sub-Saharan Africa, see Chapter 4 of Foresight Africa 2016: Capitalizing on Urbanization: The Importance of Planning, Infrastructure, and Finance for Africa’s Growing Cities.

Authors

  • Amy Copley
     
 
 




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Could the latest blunder by Egypt’s Sissi be the nail in his coffin?


Today, Egyptian President Abdel-Fattah el-Sissi is witnessing the most vocal and angry objection to his rule since he took power via a military coup in 2013. Across Cairo and beyond, Egyptians are gathering and chanting some of the same slogans from the January 2011 revolution—such as “the people want the fall of the regime” and “down with military rule.” These protests are not a spontaneous uprising. They were planned and announced on April 15, when thousands of Egyptians took to the streets, protesting the latest in a series of bold and controversial decisions that are slowly and steadily chipping away at Sissi’s once solid support structure abroad and at home.

During Saudi King Salman’s recent visit to Cairo, the Egyptian government announced that it had agreed to transfer sovereignty of two Red Sea islands—Tiran and Sanafir—to Saudi Arabia. This decision, which coincided with a $22 billion oil and aid deal, has a clear short term pay-off: a substantial Band-Aid on Egypt’s gaping economic wounds. But Sissi and his government are once again dramatically underestimating just how self-destructive their behavior can be. As my colleague Tamara Wittes eloquently noted, Egypt “continues to throw obstacles in the road of U.S.-Egyptian cooperation.” But even worse than the self-sabotage in Egypt’s foreign relations is the damage Sissi is doing to his reputation at home. 

The decision to transfer the islands to Saudi Arabia may turn out to be the final nail in Sissi’s coffin.

To the streets, again

Following the announcement of this decision, Egyptians took to Twitter, with the hashtag “leave” and “I didn’t elect Sissi” trending in Egypt. Lawyers filed lawsuits in Egyptian courts opposing the agreement. And plans were made for a much larger protest today, Sinai Liberation Day. 

But today’s protests are different than in the past. First, while the anti-Sissi protesters had time to plan and coordinate their actions, so did the regime. Today, pro-Sissi supporters organized their own protests, proudly waving the Saudi flag in Cairo’s symbolic Tahrir Square. The Egyptian Air Force painted the Egyptian flag in the sky. And the security forces came out in droves early today across greater Cairo, closing off access to most of the usual protests sites (such as the Journalists’ Syndicate and the Doctors’ Syndicate) and making a massive show of force to deter people from coming out. 

The government clearly learned a few lessons since Mubarak’s fall. A law passed in 2013 requires pre-approval from the Interior Ministry for any protest activity. That gave Sissi’s henchmen a green light to round up actual and suspected protesters as they have been doing since Thursday, arresting hundreds of suspected agitators and human rights activists on charges related to organizing today’s protests. (Notably, the pro-Sissi demonstrators have not been touched.) As each new anti-regime protest pops up today, security forces are there, arresting protesters and journalists and dispersing them with tear gas and rubber bullets. Regardless of the final outcome of today’s events, Sissi should pay attention to the growing dissatisfaction among the Egyptian people. 

The symbolism of holding today’s protests on Sinai Liberation Day is potent. Threats to Egypt’s nationalism and national sovereignty have long been key drivers of Egyptian rage, allowing the protest organizers to tap in to the anger and frustration shared by Egyptians across the political spectrum. The outrage citizens have expressed in the streets, online, and in the media should be a red flag to Sissi, who is hemorrhaging support. 

Notably, he’s now struck a nerve not just with Islamists or others in the anti-Sissi crowd, but with one of the few remaining bastions of Sissi supporters—the everyday Egyptians who are not normally politically engaged. This is a group of people who, following five years of political turmoil, see Sissi as Egypt’s best chance at stability in an increasingly unstable neighborhood. And they’re generally willing to forgive Sissi for his transgressions. They don’t believe the theory that the Egyptian security services are responsible for Italian PhD student Giulio Regeni’s death. They agree that foreign funding of NGOs is a form of Western meddling in Egyptian affairs. They justify the brutal crackdown on free expression in the name of security. But secretly concocting a deal to give away Egyptian land—that is one pill even they can’t swallow. 

Final straws?

Making matters worse are reports that Egypt consulted with Israel and the United States prior to the transfer. While the Israeli-Egyptian peace treaty remains active, Egypt and Israel’s peace is cold, at best. The notion that Sissi would consult with Israel over something that he kept secret from his own people is the ultimate insult and betrayal to many Egyptians. The facts behind the transfer matter very little. What matters is the perception of the Egyptian public that President Sissi has duped them. 

The decision to transfer the islands to Saudi Arabia may turn out to be the final nail in Sissi’s coffin. Over the past several months, he has lost other pillars of support—including secular revolutionaries, who saw former President Morsi and the Muslim Brotherhood as subverting the revolution and supported the military’s return to power. The far-reaching and brutal crackdown on Egyptian journalists and NGOs turned many of them off from Sissi. And wealthy Egyptians, who believed Sissi’s promises to grow the economy and protect their assets, have increasingly questioned their leader as Egypt’s economy continues to plummet. 

Sissi is not only running out of supporters, he is also running out of excuses.

Sissi is not only running out of supporters, he is also running out of excuses. Rather than admit his mistakes, Sissi has defended his actions, shifting the blame and feeding conspiracy theories. While protests were growing across Egypt on April 15, Sissi spoke to a group of Egyptian youth, referencing a “hellish scheme” to destabilize Egypt from within. 

Unfortunately for Sissi, there is no such “scheme.” In 2011 it was not a Western plot, as some Egyptian conspiracy theories have suggested, that ousted Mubarak—it was the Egyptian people, fed up with actions Mubarak carried out as president. In 2013, the coup that ousted Morsi succeeded because the people were fed up with decisions he made in office to consolidate power and reject democratic reforms. Had either Mubarak or Morsi spent as much time responding to the wants and needs of their citizenry as they had quashing dissent, one of them might still be in office. Much like his predecessors, what Sissi fails to understand is that the thing most likely to destabilize his government is neither an external conspiracy not an internal scheme—it’s him. 

Authors