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Methylcellulose – a versatile printing material that enables biofabrication of tissue equivalents with high shape fidelity

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Biomater. Sci., 2020, 8,2102-2110
DOI: 10.1039/D0BM00027B, Minireview
Open Access
T. Ahlfeld, V. Guduric, S. Duin, A. R. Akkineni, K. Schütz, D. Kilian, J. Emmermacher, N. Cubo-Mateo, S. Dani, M. v. Witzleben, J. Spangenberg, R. Abdelgaber, R. F. Richter, A. Lode, M. Gelinsky
This minireview highlights the use of the polysaccharide methylcellulose for biofabrication applications. Its properties are useful for printing of dissolvable support structures as well as the development of novel bioinks.
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A fluorinated low-molecular-weight PEI/HIF-1α shRNA polyplex system for hemangioma therapy

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Biomater. Sci., 2020, 8,2129-2142
DOI: 10.1039/D0BM00171F, Paper
Xiaoshuang Guo, Zihan Yuan, Yang Xu, Minyan Wei, Zhiwei Fang, Wei-En Yuan
RNAi technology targeting HIF-1α could benefit hemangioma therapy effectively and FPEI polyplexes which could inhibit the expression of HIF-1α at the translational level can provide a practicable strategy for clinical hemangioma treatment in the future.
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Cu, Zn doped borate bioactive glasses: antibacterial efficacy and dose-dependent in vitro modulation of murine dendritic cells

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Biomater. Sci., 2020, 8,2143-2155
DOI: 10.1039/C9BM01691K, Paper
Open Access
Katharina Schuhladen, Lena Stich, Jochen Schmidt, Alexander Steinkasserer, Aldo R. Boccaccini, Elisabeth Zinser
Bioactive borate glasses additionally doped with copper and/or zinc have enthralling immune-modulatory effects on immune cells.
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Balancing the thickness of sensitizing and inert layers in neodymium-sensitized tetralayer nanoconstructs for optimal ultraviolet upconversion and near-infrared cross-linked hydrogel tissue sealants

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Biomater. Sci., 2020, Advance Article
DOI: 10.1039/D0BM00453G, Paper
Zhongzheng Yu, Yong Yao Chun, Jingwen Xue, Jodie Zu Yi Tan, Wen Kiat Chan, Weizheng Cai, Yan Zhang, Timothy Thatt Yang Tan
Balancing the thickness of sensitizing and inert layers in neodymium-sensitized tetralayer nanoconstructs for optimal ultraviolet upconversion.
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Strategic reconstruction of macrophage-derived extracellular vesicles as a magnetic resonance imaging contrast agent

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Biomater. Sci., 2020, Advance Article
DOI: 10.1039/D0BM00128G, Paper
Sagar Rayamajhi, Ramesh Marasini, Tuyen Duong Thanh Nguyen, Brandon L. Plattner, David Biller, Santosh Aryal
Reconstruction of extracellular vesicles with imaging agents allows precise downstream analysis using clinical imaging modalities, for example, MRI. This will further improve the biocompatibility of agents thereby enhancing clinical investigations.
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High antimicrobial photodynamic activity of photosensitizer encapsulated dual-functional metallocatanionic vesicles against drug-resistant bacteria S. aureus

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Biomater. Sci., 2020, Advance Article
DOI: 10.1039/D0BM00323A, Paper
Bunty Sharma, Gurpreet Kaur, Ganga Ram Chaudhary, Santosh L. Gawali, P. A. Hassan
Developments in the field of photodynamic therapy (PDT) are being made by investigating appropriate photosensitizers (PSs) and enhancing the penetration effect of light by developing new metallocatanionic vesicles.
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Bacterial nanocellulose as a corneal bandage material: a comparison with amniotic membrane

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Biomater. Sci., 2020, Advance Article
DOI: 10.1039/D0BM00083C, Paper
Open Access
Irene Anton-Sales, Justin Christopher D'Antin, Jorge Fernández-Engroba, Victor Charoenrook, Anna Laromaine, Anna Roig, Ralph Michael
Bacterial nanocellulose exhibits valuable properties to act as a corneal bandage material in terms of conformability, suturability, durability and ease of manipulation in ophthalmological environments.
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Matrix stiffness-regulated cellular functions under different dimensionalities

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Biomater. Sci., 2020, Advance Article
DOI: 10.1039/C9BM01809C, Review Article
Jiajun Zhong, Yuexiong Yang, Liqiong Liao, Chao Zhang
The microenvironments that cells encounter with in vitro.
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Correction: An eximious and affordable GSH stimulus-responsive poly(α-lipoic acid) nanocarrier bonding combretastatin A4 for tumor therapy

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Biomater. Sci., 2020, Advance Article
DOI: 10.1039/D0BM90037K, Correction
Open Access
  This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.
Zhilin Liu, Na Shen, Zhaohui Tang, Dawei Zhang, Lili Ma, Chenguang Yang, Xuesi Chen
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Enhanced nanoparticle accumulation by tumor-acidity-activatable release of sildenafil to induce vasodilation

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Biomater. Sci., 2020, Advance Article
DOI: 10.1039/D0BM00466A, Paper
Peng Zhang, Yu Zhang, Xiaoya Ding, Chunsheng Xiao, Xuesi Chen
An efficient strategy to selectively promote nanoparticle accumulation in solid tumors was developed by encapsulating sildenafil in cisplatin-incorporated polymeric micelles.
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Near-infrared-persistent luminescence/bioluminescence imaging tracking of transplanted mesenchymal stem cells in pulmonary fibrosis

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Biomater. Sci., 2020, Advance Article
DOI: 10.1039/D0BM00063A, Paper
Yuyang Xia, Hongying Bao, Jie Huang, Xiaodi Li, Chenggong Yu, Zhijun Zhang, Haishui Wang
A dual-labeling strategy integrating near-infrared-persistent luminescence and RfLuc-based bioluminescence imaging techniques has been developed to track the transplanted stem cells, deepening the understanding of the role played by stem cells in PF treatment.
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Dendritic cells reprogrammed by CEA messenger RNA loaded multi-functional silica nanospheres for imaging-guided cancer immunotherapy

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Biomater. Sci., 2020, Advance Article
DOI: 10.1039/D0BM00395F, Communication
Yue Hu, Yuyin Tang, Xiao-Jing Zhang, Xiao-Tong Yang, Ying-Ying Tang, Su Li, Linyu Hu, Peng Chen, Dong Zhu
Multi-functional and hierarchically structured silica nanospheres are rationally designed and fabricated, which encapsulate quantum dots to permit near infrared deep tissue imaging and are loaded with carcinoembryonic antigen messenger RNA (CEAmRNA) to enable stable and abundant antigen expression in DCs.
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A TRACER culture invasion assay to probe the impact of cancer associated fibroblasts on head and neck squamous cell carcinoma cell invasiveness

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Biomater. Sci., 2020, Advance Article
DOI: 10.1039/C9BM02017A, Paper
Teresa Dean, Nancy T. Li, Jose L. Cadavid, Laurie Ailles, Alison P. McGuigan
A novel 3D in vitro co-culture platform to explore the interactions between cancer-associated fibroblasts and tumour cells that drive increased tumour cell invasion and the impact of matrix density.
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Disulfiram-Gold-Nanorod Integrate for Effective Tumor Targeting and Photothermal-Chemical Synergistic Therapy

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Biomater. Sci., 2020, Accepted Manuscript
DOI: 10.1039/D0BM00062K, Paper
Chaoli Xu, Ting Zhang, Guangming Lu, Kun Chen, Jun Tao, Yunlei Zhang, Zhaogang Teng, Bin Yang
Herein, we successfully constructed a combined therapeutic nanoplatform with high tumor targeting for cancer treatment by integrating gold nanorods with disulfiram (denoted Au-DSF). The Au-DSF integrates possess a uniform length...
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Fluorescence Imaging-Guided Multifunctional Liposomes for Tumor-Specific Phototherapy for Laryngeal carcinoma

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Biomater. Sci., 2020, Accepted Manuscript
DOI: 10.1039/D0BM00249F, Paper
Di Wu, zheng zhao, nan wang, xinrui zhang, honghong yan, xiaoqi chen, yunyun fan, weiwei liu, xuekui liu
Reliable diagnosed and efficient targeted therapy regime is important and may in turn lead to more effective laryngeal carcinoma treatments. Multifunctional nano-theranostic agents demonstrate great potential in tumor theranostic applications....
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A disulfide based low molecular weight gel for the selective sustained release of biomolecules

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Biomater. Sci., 2020, Advance Article
DOI: 10.1039/D0BM00508H, Paper
Nitin D. Bansode, Kotagudda Ranganath Sindhu, Chloe Morel, Murielle Rémy, Julien Verget, Claudine Boiziau, Philippe Barthélémy
Constructing biocompatible soft materials via supramolecular approaches remains an important challenge for in vivo applications.
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A conductive PEDOT/alginate porous scaffold as a platform to modulate the biological behaviors of brown adipose-derived stem cells

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Biomater. Sci., 2020, Advance Article
DOI: 10.1039/C9BM02012H, Paper
Boguang Yang, Fanglian Yao, Lei Ye, Tong Hao, Yabin Zhang, Lei Zhang, Dianyu Dong, Wancai Fang, Yan Wang, Xiaoyang Zhang, Changyong Wang, Junjie Li
The development of three-dimensional conductive scaffolds is vital to support the adhesion, proliferation and myocardial differentiation of stem cells in cardiac tissue engineering.
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Multifunctional Antibacterial Dental Sealants Suppress Biofilms Derived from Children at High Risk of Caries

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Biomater. Sci., 2020, Accepted Manuscript
DOI: 10.1039/D0BM00370K, Paper
Maria Salem Ibrahim, Isadora Martini Garcia, Taissa Vila, Abdulrahman A. Balhaddad, Fabricio Mezzomo Collares, Michael D Weir, Huakun Xu, Mary Anne Melo
Dental caries in children is a leading worldwide concern for oral health. Combining antibacterial and remineralizing additives within dental sealants is a promising approach for caries prevention. Saliva contains oral...
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In situ conversion of rose bengal microbubbles into nanoparticles for ultrasound imaging guided sonodynamic therapy with enhanced antitumor efficacy

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Biomater. Sci., 2020, 8,2526-2536
DOI: 10.1039/C9BM02046B, Paper
Rui Hou, Xiaolong Liang, Xiaoda Li, Xu Zhang, Xiaotu Ma, Fan Wang
Sonosensitizer microbubbles enhance drug accumulation and the antitumor efficacy of sonodynamic therapy by ultrasound mediated micro to nano conversion.
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A riboflavin–ultraviolet light A-crosslinked decellularized heart valve for improved biomechanical properties, stability, and biocompatibility

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Biomater. Sci., 2020, 8,2549-2563
DOI: 10.1039/C9BM01956A, Paper
Chungeng Liu, Weihua Qiao, Hong Cao, Jinchi Dai, Fei Li, Jiawei Shi, Nianguo Dong
Riboflavin–ultraviolet light A could effectively crosslink a decellularized heart valve to improve its biomechanical properties, stability and biocompatibility.
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Engineering red-emitting multi-functional nanocapsules for magnetic tumour targeting and imaging

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Biomater. Sci., 2020, 8,2590-2599
DOI: 10.1039/D0BM00314J, Paper
Julie Tzu-Wen Wang, Umberto Martino, Rehan Khan, Maasoomeh Bazzar, Paul Southern, Dönüş Tuncel, Khuloud T. Al-Jamal
Self-red-emitting magnetic PLGA-PEG nanocapsules for optical imaging and magnetic tumour targeting.
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Biomimic strategies for modulating the interaction between particle adjuvants and antigen-presenting cells

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Biomater. Sci., 2020, 8,2366-2375
DOI: 10.1039/C9BM02098E, Review Article
Jie Wu, Guanghui Ma
The design strategies of particle adjuvants by mimicking natural pathogens to strengthen their interaction with antigen-presenting cells.
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A nanosystem loaded with perfluorohexane and rose bengal coupled upconversion nanoparticles for multimodal imaging and synergetic chemo-photodynamic therapy of cancer

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Biomater. Sci., 2020, 8,2488-2506
DOI: 10.1039/C9BM02081K, Paper
Hai-yan Wang, Li Hou, Hai-liang Li, Xu Wang, Yang Cao, Bo-yu Zhang, Jing-tao Wang, Shi-jie Wei, Hong-wan Dang, Hai-tao Ran
A novel nanosystem (FURH-PFH-NPs) combined with LIFU and laser irradiation realized multimodal imaging, targeted release of HCPT, UCNPs-RB and synergetic chemo-photodynamic therapy of cancer.
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Enhanced selectivity, cellular uptake, and in vitro activity of an intrinsically fluorescent copper–tirapazamine nanocomplex for hypoxia targeted therapy in prostate cancer

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Biomater. Sci., 2020, 8,2420-2433
DOI: 10.1039/C9BM01905G, Paper
Vera L. Silva, Abdessamad Kaassis, Ashkan Dehsorkhi, Cédrik-Roland Koffi, Maja Severic, Moustafa Abdelhamid, Duuamene Nyimanu, Christopher J. Morris, Wafa’ T. Al-Jamal
Cu(TPZ)2 complex as a promising hypoxia selective cytotoxin in prostate cancer.
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Bioinspired inorganic nanoparticles and vascular factor microenvironment directed neo-bone formation

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Biomater. Sci., 2020, 8,2627-2637
DOI: 10.1039/D0BM00041H, Paper
Hwan D. Kim, Jungha Park, Sivashanmugam Amirthalingam, R. Jayakumar, Nathaniel S. Hwang
VEGF-overexpressing human tonsil-derived stem cells (VEGF-hTMSCs) and a whitlockite microenvironment induce vascularized bone tissue formation in biodegradable polymeric scaffolds.
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Assembly of FN-silk with laminin-521 to integrate hPSCs into a three-dimensional culture for neural differentiation

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Biomater. Sci., 2020, 8,2514-2525
DOI: 10.1039/C9BM01624D, Paper
Open Access
  This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.
Carolina Åstrand, Veronique Chotteau, Anna Falk, My Hedhammar
The functionalized recombinant spider silk protein FN-silk can self-assemble into a 3D microfiber network. When combined with recombinant laminin521 it provides a 3D culture system suitable for expansion of hPSCs and following neural differentiation.
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Injectable hydrogel systems with multiple biophysical and biochemical cues for bone regeneration

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Biomater. Sci., 2020, 8,2537-2548
DOI: 10.1039/D0BM00104J, Paper
Weinan Cheng, Zhaozhao Ding, Xin Zheng, Qiang Lu, Xiangdong Kong, Xiaozhong Zhou, Guozhong Lu, David L. Kaplan
Tunable multiple angiogenic and osteogenic cues were introduced into hydrogel systems simultaneously to optimize the niches for bone regeneration.
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NIR-emitting semiconducting polymer nanoparticles for in vivo two-photon vascular imaging

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Biomater. Sci., 2020, 8,2666-2672
DOI: 10.1039/C9BM02063B, Paper
Xiao-Ting Gong, Wenguang Xie, Jing-Jing Cao, Shengxiang Zhang, Kanyi Pu, Hao-Li Zhang
A NIR-emitting TPF probe (NESPN) was prepared using semiconducting polymers and used for continuously monitoring the whole process of ischemic stroke and subsequent reperfusion. This work provides a new and versatile tool for vascular research and diagnosis of vascular diseases.
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Spatial immobilization of endogenous growth factors to control vascularization in bone tissue engineering

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Biomater. Sci., 2020, 8,2577-2589
DOI: 10.1039/D0BM00087F, Paper
Marta R. Casanova, Catarina Oliveira, Emanuel M. Fernandes, Rui L. Reis, Tiago H. Silva, Albino Martins, Nuno M. Neves
An engineered biofunctional system comprises endogenous BMP-2 and VEGF bound in a parallel pattern. It successfully enabled obtaining the spatial osteogenic and angiogenic differentiation of human hBM-MSCs under basal culture conditions.
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The electrospinning of a thermo-responsive polymer with peptide conjugates for phenotype support and extracellular matrix production of therapeutically relevant mammalian cells

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Biomater. Sci., 2020, 8,2611-2626
DOI: 10.1039/C9BM01965K, Paper
Open Access
  This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.
F. A. A. Ruiter, L. E. Sidney, K. L. Kiick, J. I. Segal, C. Alexander, F. R. A. J. Rose
The fabrication and application of a biocompatible peptide conjugated thermo-responsive fibrous scaffolds for cellular phenotype support and enzymatic-free passaging of mammalian cells.
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A multifunctional metal-biopolymer coordinated double network hydrogel combined with multi-stimulus responsiveness, self-healing, shape memory and antibacterial properties

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Biomater. Sci., 2020, Advance Article
DOI: 10.1039/D0BM00425A, Paper
Kun Yan, Feiyang Xu, Chunyu Wang, Yingying Li, Yuanli Chen, Xiufang Li, Zhentan Lu, Dong Wang
A universal, straightforward macroscale assembly technology has been presented for fabrication of polysaccharide-based multifunctional DN gels based on metal coordination chemistry.
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Modulating neutrophil extracellular traps for wound healing

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Biomater. Sci., 2020, Advance Article
DOI: 10.1039/D0BM00355G, Paper
Tejinder Kaur, Shweta Dumoga, Veena Koul, Neetu Singh
An alginate-GelMa scaffold for modulating neutrophil extracellular traps using a PAD4 inhibitor could be a novel therapeutic approach for wound healing.
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A super-stretchable, self-healing and injectable supramolecular hydrogel constructed by a host–guest crosslinker

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Biomater. Sci., 2020, Advance Article
DOI: 10.1039/D0BM00290A, Paper
Yang Zhou, Yuanhao Zhang, Zhaobo Dai, Fang Jiang, Jia Tian, Weian Zhang
Supramolecular hydrogels based on host–guest interactions have drawn considerable attention due to their unique properties and promising applications.
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A versatile ultrafine and super-absorptive H+-modified montmorillonite: application for metabolic syndrome intervention and gastric mucosal protection

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Biomater. Sci., 2020, Advance Article
DOI: 10.1039/D0BM00474J, Paper
Qiwen Wang, Jie Shen, Enqi Mo, Haotian Zhang, Jianwei Wang, Xiurong Hu, Jun Zhou, Hongzhen Bai, Guping Tang
An H+-modified montmorillonite (H-MMT) was prepared using an acid modification method to obtain powerful absorption ability as a theranostic platform for both metabolic syndrome and gastric mucosa protection.
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Optically controlled hybrid metamaterial of plasmonic spiky gold inbuilt graphene sheets for bimodal imaging guided multimodal therapy

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Biomater. Sci., 2020, Advance Article
DOI: 10.1039/D0BM00312C, Paper
Kunnumpurathu Jibin, Jayaram S. Prasad, Giridharan Saranya, Sachin J. Shenoy, Kaustabh K. Maiti, Ramapurath S. Jayasree
Gold–graphene nanohybrid for simultaneous dual-imaging guided triple therapy as a new paradigm in light-triggered cancer theranostics. The material demonstrates excellent therapeutic efficacy and treatment monitoring features.
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Effective intracellular delivery of bevacizumab via PEGylated polymeric nanoparticles targeting CD44v6 receptor in colon cancer cells

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Biomater. Sci., 2020, Accepted Manuscript
DOI: 10.1039/D0BM00556H, Paper
Ana Baião, Flávia Sousa, Ana Oliveira, Carla Oliveira, Bruno Sarmento
Colorectal cancer (CRC) is one of the most incident and mortal cancers in the world, mainly due to its metastatic and metabolic ability. CD44 receptor isoform containing exon 6 (CD44v6)...
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Kaempferol derivatives isolated from Lens culinaris Medik. reduce DNA damage induced by etoposide in peripheral blood mononuclear cells

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Toxicol. Res., 2019, 8,896-907
DOI: 10.1039/C9TX00176J, Paper
Magdalena Kluska, Michał Juszczak, Daniel Wysokiński, Jerzy Żuchowski, Anna Stochmal, Katarzyna Woźniak
Bioactive compounds isolated from plants are considered to be attractive candidates for cancer therapy.
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Gynura divaricata ameliorates hepatic insulin resistance by modulating insulin signalling, maintaining glycolipid homeostasis and reducing inflammation in type 2 diabetic mice

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Toxicol. Res., 2019, 8,928-938
DOI: 10.1039/C9TX00191C, Paper
Xuan Dong, Shu-Xiang Zhao, Bing-Qing Xu, Yu-Qing Zhang
Oral lyophilized powder of Gynura divaricata, an edible medicinal plant, can alleviate both hyperglycaemia and hepatic insulin resistance in type 2 diabetic mice.
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Lipoic acid antagonizes paraquat-induced vascular endothelial dysfunction by suppressing mitochondrial reactive oxidative stress

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Toxicol. Res., 2019, 8,918-927
DOI: 10.1039/C9TX00186G, Paper
Li Pang, Ping Deng, Yi-dan Liang, Jing-yu Qian, Li-Chuan Wu, Ling-ling Yang, Zheng-ping Yu, Zhou Zhou
α-Lipoic acid antagonizes paraquat toxicity.
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Thyroid endocrine status and biochemical stress responses in adult male Wistar rats chronically exposed to pristine polystyrene nanoplastics

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Toxicol. Res., 2019, 8,953-963
DOI: 10.1039/C9TX00147F, Paper
Fatemeh Amereh, Akbar Eslami, Simin Fazelipour, Mohammad Rafiee, Mohammad Ismail Zibaii, Mohammad Babaei
At this time, little is known about the long-term effects of micro(nano)plastics on public health. In the present study, early warning signs of thyroid endocrine disruption were noticed in adult Wistar rats from the ingestion of virgin polystyrene nanoparticles.
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Reply to the ‘Comment on “Acetylcysteine in paracetamol poisoning: a perspective of 45 years of use”’ by M. E. Mullins, M. C. Yarema, M. L. A. Sivilotti, M. Thompson, D. A. Algren, M. C. Beuhler and C. P. Holstege, Toxicol. Res., 2019, 8, DOI: 10.1039/C9T

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Toxicol. Res., 2019, 8,1059-1059
DOI: 10.1039/C9TX00216B, Comment
Open Access
D. Nicholas Bateman, James W. Dear
Mullins et al. made a comment on our article (DOI: 10.1039/C9TX00002J) stating they noticed the omission of the one-bag, standard concentration protocol which is shared by several centers in North America when we discussed IV acetylcysteine protocols.
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Cadmium telluride quantum dot-exposed human bronchial epithelial cells: a further study of the cellular response by proteomics

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Toxicol. Res., 2019, 8,994-1001
DOI: 10.1039/C9TX00126C, Paper
Yan-Ming Xu, Heng Wee Tan, Wei Zheng, Zhan-Ling Liang, Fei-Yuan Yu, Dan-Dan Wu, Yue Yao, Qiu-Hua Zhong, Rui Yan, Andy T. Y. Lau
A comparative proteome analysis was conducted to identify global changes in the protein expression profiles of cadmium telluride quantum dot-exposed human bronchial epithelial BEAS-2B cells.
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Novel evaluation of sevoflurane anesthetic exposure on the testicular germ cells of neonatal male mice

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Toxicol. Res., 2019, 8,988-993
DOI: 10.1039/C9TX00193J, Paper
Ali Raza Ebrahim Soltani, Abdolmohammad Kajbafzadeh, Maryam Ezzati, Zahra Ebrahim Soltani, Navid Hosseinifar, Anahid Maleki, Maryam Nezhad Sistani
Inhalatory anesthetics may impact spermatogenesis and sexual behavior.
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Mice with a Sertoli cell-specific knockout of the Ctr1 gene exhibit a reduced sensitivity to cisplatin-induced testicular germ cell apoptosis

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Toxicol. Res., 2019, 8,972-978
DOI: 10.1039/C9TX00142E, Paper
Open Access
Rashin Ghaffari, John H. Richburg
Exposure to the chemotherapeutic agent cis-diamminedichloroplatinum(II) (cDDP) is well known to instigate acute and prolonged testicular injury in male patients.
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Effects of moderate red wine on cardiovascular risk factors in diabetics: a systematic review and meta-analysis of randomized controlled trials

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Toxicol. Res., 2019, 8,979-987
DOI: 10.1039/C9TX00227H, Paper
Saavia Alice Naame, Decheng Li, Ruixue Huang
Diabetes mellitus is of major public health concerns; its incidence is continuously increasing.
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Methanol extract of Iphiona aucheri ameliorates CCl4 induced hepatic injuries by regulation of genes in rats

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Toxicol. Res., 2019, 8,815-832
DOI: 10.1039/C9TX00157C, Paper
Jawaid Ahmed Zai, Muhammad Rashid Khan, Zaib un Nisa Mughal, Riffat Batool, Irum Naz, Sonia Maryam, Zartash Zahra
Alteration in expression of ER stress associated genes, inflammatory genes and antioxidant biochemical induced with CCl4 in liver of rats were restored towards the control rats by co-administration of methanol extract of Iphiona aucheri to rats.
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Cytotoxic effect of silica nanoparticles against hepatocellular carcinoma cells through necroptosis induction

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Toxicol. Res., 2019, 8,1042-1049
DOI: 10.1039/C9TX00240E, Paper
Yuexiang Niu, Engong Tang, Qingan Zhang
Hepatocellular carcinoma (HCC) is a common cancer that affects people worldwide with high morbidity and mortality, and its resistance to current chemotherapeutic drugs is a serious concern.
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Central Board of Direct Taxes amends Rule 44G of Income-tax Rules 1962

By www.business-standard.com
Published On :: Fri, 08 May 2020 10:34:00 +0530

It also states that if a resolution is arrived, the same shall be communicated to the assessee, who shall communicate his acceptance or non-acceptance within 30 days


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SC's struggles with 'unruly horse' of public policy in foreign awards

By www.business-standard.com
Published On :: Fri, 08 May 2020 11:58:00 +0530

The Nafed-Alimenta judgment shows it might perhaps be time for Parliament to intervene and clarify the notion of public policy in the context of foreign arbitral awards


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Export contraction in April could surpass March's steep 25-year decline

By www.business-standard.com
Published On :: Fri, 08 May 2020 19:02:00 +0530

Major forex earning sectors cite lack of labour, funds and key supplies


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