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ECM-based microchannel for culturing in vitro vascular tissues with simultaneous perfusion and stretch

Lab Chip, 2020, Advance Article
DOI: 10.1039/D0LC00254B, Paper
Azusa Shimizu, Wei Huang Goh, Shun Itai, Michinao Hashimoto, Shigenori Miura, Hiroaki Onoe
A perfusable and stretchable gelatin-based microfluidic system that can apply both simultaneous fluidic shear stress and stretch stress to in vitro endothelial 3D tissues is presented.
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Seeded droplet microfluidic system for small molecule crystallization

Lab Chip, 2020, Advance Article
DOI: 10.1039/D0LC00122H, Paper
N. Garg, R. Tona, P. Martin, P. M. Martin-Soladana, G. Ward, N. Douillet, D. Lai
A microfluidic approach to seeded crystallization has been demonstrated using abacavir hemisulfate, a nucleoside analog reverse transcriptase inhibitor, in droplet reactors to control polymorphism and produce particles with a low particle size distribution.
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A new microfluidic model that allows monitoring of complex vascular structures and cell interactions in a 3D biological matrix

Lab Chip, 2020, Advance Article
DOI: 10.1039/D0LC00059K, Paper
Open Access
Christian G. M. van Dijk, Maarten M. Brandt, Nikolaos Poulis, Jonas Anten, Matthijs van der Moolen, Liana Kramer, Erik F. G. A. Homburg, Laura Louzao-Martinez, Jiayi Pei, Merle M. Krebber, Bas W. M. van Balkom, Petra de Graaf, Dirk J. Duncker, Marianne C. Verhaar, Regina Luttge, Caroline Cheng
We present a microfluidic vascular device. Vascular cells in a 3D-ECM environment support hemodynamic flow and enable monocyte interaction.
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Microfluidic device for high-throughput affinity-based isolation of extracellular vesicles

Lab Chip, 2020, Advance Article
DOI: 10.1039/C9LC01190K, Paper
Ting-Wen Lo, Ziwen Zhu, Emma Purcell, Daniel Watza, Joyful Wang, Yoon-Tae Kang, Shruti Jolly, Deepak Nagrath, Sunitha Nagrath
Immunoaffinity based EV isolation technologies use antibodies targeting surface markers on EVs to provide higher isolation specificity and purity compared to existing approaches.
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In situ generation of plasma-activated aerosols via surface acoustic wave nebulization for portable spray-based surface bacterial inactivation

Lab Chip, 2020, Advance Article
DOI: 10.1039/D0LC00001A, Paper
Kiing S. Wong, William T. H. Lim, Chien W. Ooi, Leslie Y. Yeo, Ming K. Tan
We demonstrate an efficient technique for in situ production and application of plasma-activated aerosols for surface disinfection.
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Photonic crystal-based smart contact lens for continuous intraocular pressure monitoring

Lab Chip, 2020, Advance Article
DOI: 10.1039/C9LC01268K, Paper
Bohee Maeng, Hyung-kwan Chang, Jungyul Park
A powerless smart contact lens enabling to monitor intraocular pressure (IOP) by checking the visual color change in photonic crystal structure with a microhydraulic amplification system has been realized.
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Multiplexed homogeneous digital immunoassay based on single-particle motion analysis

Lab Chip, 2020, Advance Article
DOI: 10.1039/D0LC00079E, Paper
Kenji Akama, Hiroyuki Noji
Homogeneous digital immunoassay is a powerful analytical method for highly sensitive biomarker detection with a simple protocol. By using this method, we demonstrated the simultaneous multiple protein detection.
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Bioinspired reconfiguration of 3D printed microfluidic hydrogels via automated manipulation of magnetic inks

Lab Chip, 2020, Advance Article
DOI: 10.1039/D0LC00280A, Communication
Amin Mansoorifar, Anthony Tahayeri, Luiz E. Bertassoni
We proposed a novel concept for reconfiguration of hydrogel microfluidic devices, where multiple fluidic pathways could be generated via reversible manipulation of magnetic inks.
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Capacitive Sensing of Triglyceride Film Reactions: A Proof-of-Concept Demonstration for Sensing in Simulated Duodenal Contents with Gastrointestinal Targeting Capsule System

Lab Chip, 2020, Accepted Manuscript
DOI: 10.1039/D0LC00133C, Paper
George Banis, Luke Beardslee, Justin Stine, Rajendra Mayavan Sathyam, Reza Ghodssi
Ingestible capsule systems continue evolving to overcome drawbacks associated with traditional gastrointestinal (GI) diagnostic and therapeutic processes, such as location restrictions or insufficient sensitivity measures when obtaining information on local...
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Multiscale brain research on a microfluidic chip

Lab Chip, 2020, 20,1531-1543
DOI: 10.1039/C9LC01010F, Critical Review
Yanan Zhao, Utkan Demirci, Yun Chen, Pu Chen
We report recent progress in applying innovative microfluidic chip-based neurotechnologies to promote multiscale brain research across the hierarchical organizations from the molecular, cellular, and tissue levels up to the whole organism level.
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Electrostatically gated nanofluidic membrane for ultra-low power controlled drug delivery

Lab Chip, 2020, 20,1562-1576
DOI: 10.1039/D0LC00121J, Paper
Open Access
Nicola Di Trani, Antonia Silvestri, Antons Sizovs, Yu Wang, Donald R. Erm, Danilo Demarchi, Xuewu Liu, Alessandro Grattoni
Control of molecular diffusion through nanofluidic channels using electrostatic gating.
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3-Step flow focusing enables multidirectional imaging of bioparticles for imaging flow cytometry

Lab Chip, 2020, 20,1676-1686
DOI: 10.1039/D0LC00244E, Paper
Open Access
  This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.
Andreas Kleiber, Anuradha Ramoji, Günter Mayer, Ute Neugebauer, Jürgen Popp, Thomas Henkel
The control of the focus plane allows multi-directional imaging flow cytometry.
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Smartphone-based multiplex 30-minute nucleic acid test of live virus from nasal swab extract

Lab Chip, 2020, 20,1621-1627
DOI: 10.1039/D0LC00304B, Paper
Fu Sun, Anurup Ganguli, Judy Nguyen, Ryan Brisbin, Krithika Shanmugam, David L. Hirschberg, Matthew B. Wheeler, Rashid Bashir, David M. Nash, Brian T. Cunningham
A 30-minute nucleic acid test for equine respiratory virus from nasal swab material, detected with a smartphone.
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Microfluidic assessment of red blood cell mediated microvascular occlusion

Lab Chip, 2020, Accepted Manuscript
DOI: 10.1039/D0LC00112K, Paper
Yuncheng Man, Erdem Kucukal, Ran An, Quentin Watson, Jürgen Bosch, Peter A. Zimmerman, Jane A Little, Umut A. Gurkan
Abnormal red blood cells (RBC) deformability contributes to hemolysis, thrombophilia, inflammation, and microvascular occlusion in various circulatory diseases. A quantitative and objective assessment of microvascular occlusion mediated by RBCs with...
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Evaluation of intercellular communication between breast cancer cells and adipose-derived stem cells via passive diffusion in a two-layer microfluidic device

Lab Chip, 2020, Advance Article
DOI: 10.1039/D0LC00142B, Paper
Sharif M. Rahman, Joshua M. Campbell, Rachael N. Coates, Katie M. Render, C. Ethan Byrne, Elizabeth C. Martin, Adam T. Melvin
Breast cancer cells co-cultured with adipose-derived stem cells (ASCs) in a microfluidic device exhibited enhanced growth, a more aggressive morphology and polarization towards the ASCs, and increased drug resistance.
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Putin to Modi: Here’s Forbes’ 10 most powerful people in 2015




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#ie100: Narendra Modi to Ravish Kumar, the most powerful Indians




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[ASAP] SPREAD: A Fully Automated Toolkit for Single-Particle Cryogenic Electron Microscopy Data 3D Reconstruction with Image-Network-Aided Orientation Assignment

Journal of Chemical Information and Modeling
DOI: 10.1021/acs.jcim.9b01099




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[ASAP] Donepezil Inhibits Acetylcholinesterase via Multiple Binding Modes at Room Temperature

Journal of Chemical Information and Modeling
DOI: 10.1021/acs.jcim.9b01073




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[ASAP] What Could Go Wrong? A Practical Guide to Single-Particle Cryo-EM: From Biochemistry to Atomic Models

Journal of Chemical Information and Modeling
DOI: 10.1021/acs.jcim.9b01178




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[ASAP] Structural Biology in the Multi-Omics Era

Journal of Chemical Information and Modeling
DOI: 10.1021/acs.jcim.9b01164




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[ASAP] Flexible Fitting of Small Molecules into Electron Microscopy Maps Using Molecular Dynamics Simulations with Neural Network Potentials

Journal of Chemical Information and Modeling
DOI: 10.1021/acs.jcim.9b01167




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[ASAP] Simulation-Based Methods for Model Building and Refinement in Cryoelectron Microscopy

Journal of Chemical Information and Modeling
DOI: 10.1021/acs.jcim.0c00087




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[ASAP] Propagation of Conformational Coordinates Across Angular Space in Mapping the Continuum of States from Cryo-EM Data by Manifold Embedding

Journal of Chemical Information and Modeling
DOI: 10.1021/acs.jcim.9b01115




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[ASAP] The Synthesizability of Molecules Proposed by Generative Models

Journal of Chemical Information and Modeling
DOI: 10.1021/acs.jcim.0c00174




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[ASAP] Molecular Perception for Visualization and Computation: The Proxima Library

Journal of Chemical Information and Modeling
DOI: 10.1021/acs.jcim.0c00076




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[ASAP] Mechanism-Based Rational Discovery and <italic toggle="yes">In Vitro</italic> Evaluation of Novel Microtubule Stabilizing Agents with Non-Taxol-Competitive Activity

Journal of Chemical Information and Modeling
DOI: 10.1021/acs.jcim.9b01133




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[ASAP] Brick-CFCMC: Open Source Software for Monte Carlo Simulations of Phase and Reaction Equilibria Using the Continuous Fractional Component Method

Journal of Chemical Information and Modeling
DOI: 10.1021/acs.jcim.0c00334




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[ASAP] Discovery of Ubiquitin-Specific Protease 7 (USP7) Inhibitors with Novel Scaffold Structures by Virtual Screening, Molecular Dynamics Simulation, and Biological Evaluation

Journal of Chemical Information and Modeling
DOI: 10.1021/acs.jcim.0c00154




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[ASAP] Ranking Molecules with Vanishing Kernels and a Single Parameter: Active Applicability Domain <italic toggle="yes">Included</italic>

Journal of Chemical Information and Modeling
DOI: 10.1021/acs.jcim.9b01075




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[ASAP] Evaluating Scalable Uncertainty Estimation Methods for Deep Learning-Based Molecular Property Prediction

Journal of Chemical Information and Modeling
DOI: 10.1021/acs.jcim.9b00975




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[ASAP] Multisolvent Models for Solvation Free Energy Predictions Using 3D-RISM Hydration Thermodynamic Descriptors

Journal of Chemical Information and Modeling
DOI: 10.1021/acs.jcim.0c00065




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[ASAP] Augmenting Hit Identification by Virtual Screening Techniques in Small Molecule Drug Discovery

Journal of Chemical Information and Modeling
DOI: 10.1021/acs.jcim.0c00113




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[ASAP] A Community Letter Regarding Sharing Biomolecular Simulation Data for COVID-19

Journal of Chemical Information and Modeling
DOI: 10.1021/acs.jcim.0c00319




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[ASAP] Understanding the Contributions of Microscopic Heat Transfer to Thermal Conductivities of Liquid Aldehydes and Ketones by Molecular Dynamics Simulation

Journal of Chemical Information and Modeling
DOI: 10.1021/acs.jcim.0c00184




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[ASAP] Scope of 3D Shape-Based Approaches in Predicting the Macromolecular Targets of Structurally Complex Small Molecules Including Natural Products and Macrocyclic Ligands

Journal of Chemical Information and Modeling
DOI: 10.1021/acs.jcim.0c00161




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[ASAP] Unraveling the Electric Field-Induced Second Harmonic Generation Responses of Stilbazolium Ion Pairs Complexes in Solution Using a Multiscale Simulation Method

Journal of Chemical Information and Modeling
DOI: 10.1021/acs.jcim.9b01161




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[ASAP] Matched Molecular Series Analysis for ADME Property Prediction

Journal of Chemical Information and Modeling
DOI: 10.1021/acs.jcim.0c00269




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[ASAP] Ranking of Ligand Binding Kinetics Using a Weighted Ensemble Approach and Comparison with a Multiscale Milestoning Approach

Journal of Chemical Information and Modeling
DOI: 10.1021/acs.jcim.9b00968




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[ASAP] Computational Insights into Molecular Activation and Positive Cooperative Mechanisms of FFAR1 Modulators

Journal of Chemical Information and Modeling
DOI: 10.1021/acs.jcim.0c00030




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Hidden Criticism?: the Methodology and Plausibility of the Search for a Counter-Imperial Subtext in Paul.

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Pope Francis as a global actor: where politics and theology meet / Alynna J. Lyon, Christine A. Gustafson, Paul Christopher Manuel, editors

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Relación de la causa de Juana María, mulata: esclava, mulata y hechicera: historia inquisitorial de una mujer novohispana del siglo XVIII / edición, Alma Leticia Mejía González

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Compulsion in religion: Saddam Hussein, Islam, and the roots of insurgencies in Iraq / Samuel Helfont

Dewey Library - BP173.6.H45 2018




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Rewriting masculinity: Gideon, men, and might / Kelly J. Murphy

Hayden Library - BS580.G5 M87 2019




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Recent developments in midrash research: proceedings of the 2002 and 2003 SBL Consultation on Midrash / Lieve M. Teugels and Rivka Ulmer, editors

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The Tawhidi methodological worldview: a transdisciplinary study of Islamic economics / editor: Masudul Alam Choudhury

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Heiligung bei Paulus: ein Beitrag aus biblisch-theologischer Sicht / Hanna Stettler

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Das Endgericht bei Paulus: Framesemantische und exegetische Studien zur paulinischen Eschatologie und Soterologie.

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Lead with Heart in Mind: Treading the Noble Eightfold Path for Mindful and Sustainable Practice / Joan Marques

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