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Protease-Responsive Mass Barcoded Nanotranslaters for Simultaneously Quantifying the Intracellular Activity of Cascaded Caspases in Apoptosis Pathways

Chem. Sci., 2020, Accepted Manuscript
DOI: 10.1039/D0SC01534B, Edge Article
Open Access
Hongmei Xu, Xiaodan Huang, Zhenzhen Zhang, xuemeng zhang, Qianhao Min, Jun-Jie Zhu
Quantitatively delineating the activation network of multiple proteases that participate in cellular processes is highly essential to understanding physiological and pathological states of cells. In this study, protease-responsive mass barcoded...
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Pore engineering of ultrathin covalent organic framework membranes for organic solvent nanofiltration and molecular sieving

Chem. Sci., 2020, Advance Article
DOI: 10.1039/D0SC01679A, Edge Article
Open Access
Digambar B. Shinde, Li Cao, A. D. Dinga Wonanke, Xiang Li, Sushil Kumar, Xiaowei Liu, Mohamed N. Hedhili, Abdul-Hamid Emwas, Matthew Addicoat, Kuo-Wei Huang, Zhiping Lai
Pore surface engineering of ultrathin COF membranes by introducing different lengths of alkyl chains into the skeleton, which allows us to precisely control the pore size of COF membranes for OSN applications and molecular sieving.
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Recent developments in nickel-catalyzed intermolecular dicarbofunctionalization of alkenes

Chem. Sci., 2020, 11,4287-4296
DOI: 10.1039/C9SC06006E, Minireview
Open Access
Joseph Derosa, Omar Apolinar, Taeho Kang, Van T. Tran, Keary M. Engle
Nickel-catalyzed three-component alkene difunctionalization has rapidly emerged as a powerful tool for forging multiple C–C bonds in a single step.
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Redox-responsive supramolecular polymeric networks having double-threaded inclusion complexes

Chem. Sci., 2020, 11,4322-4331
DOI: 10.1039/C9SC05589D, Edge Article
Open Access
Hikaru Aramoto, Motofumi Osaki, Subaru Konishi, Chiharu Ueda, Yuichiro Kobayashi, Yoshinori Takashima, Akira Harada, Hiroyasu Yamaguchi
A hydrogel actuator with a 1:2 host–guest complex controlled by redox stimuli has been developed to realize faster and larger deformation.
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Peculiar bond characters of fivefold coordinated octet compound crystals

Chem. Sci., 2020, 11,4340-4350
DOI: 10.1039/D0SC00292E, Edge Article
Open Access
  This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.
An-An Sun, Shang-Peng Gao, Gong Gu
A refreshed view of chemical bonds in solids unveils unusual bonding in fivefold coordinated bulk crystals of octet compounds: out-of-plane cation–anion chain bonding via overlapping pz orbitals replaces in-plane π bonding of the isolated monolayer.
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An RGB-emitting molecular cocktail for the detection of bacterial fingerprints

Chem. Sci., 2020, 11,4403-4409
DOI: 10.1039/D0SC01704C, Edge Article
Open Access
Sheng Hong, Di-Wei Zheng, Qiu-Ling Zhang, Wei-Wei Deng, Wen-Fang Song, Si-Xue Cheng, Zhi-Jun Sun, Xian-Zheng Zhang
A technique named the Microcolor system was developed to detect microbes and diagnose diseases based on changes in microbiota signatures.
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Redox-inactive ions control the redox-activity of molecular vanadium oxides

Chem. Sci., 2020, 11,4450-4455
DOI: 10.1039/D0SC01401J, Edge Article
Open Access
  This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.
Simon Greiner, Benjamin Schwarz, Mark Ringenberg, Maximilian Dürr, Ivana Ivanovic-Burmazovic, Maximilian Fichtner, Montaha Anjass, Carsten Streb
The enhanced redox-activity of a molecular vanadium oxide cluster upon functionalization with redox-inert Ca2+ ions is reported together with initial insights into its performance as a lithium ion battery cathode.
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Intramolecular Csp3–H/C–C bond amination of alkyl azides for the selective synthesis of cyclic imines and tertiary amines

Chem. Sci., 2020, 11,4482-4487
DOI: 10.1039/C9SC05522C, Edge Article
Open Access
Xiaojin Wen, Xinyao Li, Xiao Luo, Weijin Wang, Song Song, Ning Jiao
A novel intramolecular cyclization of alkyl azides for the synthesis of cyclic imines and tertiary amines has been developed. The aliphatic C–H or C–C bond was selectively cleaved with the efficient formation of two C–N single bonds or a CN double bond.
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Chemical synthesis and immunological evaluation of new generation multivalent anticancer vaccines based on a Tn antigen analogue

Chem. Sci., 2020, 11,4488-4498
DOI: 10.1039/D0SC00544D, Edge Article
Open Access
Carlo Pifferi, Ane Ruiz-de-Angulo, David Goyard, Claire Tiertant, Nagore Sacristán, Diego Barriales, Nathalie Berthet, Juan Anguita, Olivier Renaudet, Alberto Fernández-Tejada
A fully-synthetic anticancer vaccine candidate incorporating an hexadecavalent Tn antigen analogue display via oxime linkages induced tumor-specific IgG antibodies and cellular immune responses in mice coadministered with QS-21 as an adjuvant.
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Self-assembly of reversed bilayer vesicles through pnictogen bonding: water-stable supramolecular nanocontainers for organic solvents

Chem. Sci., 2020, 11,4374-4380
DOI: 10.1039/D0SC00206B, Edge Article
Open Access
Shiva Moaven, Brandon T. Watson, Shelby B. Thompson, Veronica J. Lyons, Daniel K. Unruh, Dominick J. Casadonte, Dimitri Pappas, Anthony F. Cozzolino
A new air and moisture stable antimony thiolate compound has been prepared that spontaneously forms stable hollow vesicles.
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Biocatalytic reversible control of the stiffness of DNA-modified responsive hydrogels: applications in shape-memory, self-healing and autonomous controlled release of insulin

Chem. Sci., 2020, 11,4516-4524
DOI: 10.1039/D0SC01319F, Edge Article
Open Access
  This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.
Chen Wang, Amit Fischer, Avner Ehrlich, Yaakov Nahmias, Itamar Willner
Biocatalytic control over the stiffness of pH-responsive hydrogels is applied to develop shape-memory, self-healing and controlled release matrices.
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Mapping the multi-step mechanism of a photoredox catalyzed atom-transfer radical polymerization reaction by direct observation of the reactive intermediates

Chem. Sci., 2020, 11,4475-4481
DOI: 10.1039/D0SC01194K, Edge Article
Open Access
Luke Lewis-Borrell, Mahima Sneha, Aditi Bhattacherjee, Ian P. Clark, Andrew J. Orr-Ewing
Short-lived intermediates are tracked in real-time by transient absorption spectroscopy during a multi-step photoredox catalysed polymerization reaction.
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Self-enhanced multicolor electrochemiluminescence by competitive electron-transfer processes

Chem. Sci., 2020, 11,4508-4515
DOI: 10.1039/D0SC00853B, Edge Article
Open Access
  This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.
Silvia Voci, Romain Duwald, Stéphane Grass, David J. Hayne, Laurent Bouffier, Paul S. Francis, Jérôme Lacour, Neso Sojic
Controlling electrochemiluminescence (ECL) color(s) is crucial for many applications ranging from multiplexed bioassays to ECL microscopy.
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Multifunctional streptavidin–biotin conjugates with precise stoichiometries

Chem. Sci., 2020, 11,4422-4429
DOI: 10.1039/D0SC01589J, Edge Article
Open Access
  This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.
Dongdong Xu, Seraphine V. Wegner
Multifunctional streptavidin-biotin conjugates with defined stoichiometry and number of open binding pockets provide molecularly precise alternatives to the statistical mixture of products that typically forms.
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Small-molecule fluorescent probes for imaging gaseous signaling molecules: current progress and future implications

Chem. Sci., 2020, Advance Article
DOI: 10.1039/D0SC01482F, Perspective
Open Access
Mingwang Yang, Jiangli Fan, Jianjun Du, Xiaojun Peng
This perspective article aims to introduce the design principles and recognition strategies of small-molecule fluorescent probes which are applied for the detection of gas signaling molecules including NO, CO and H2S in biological systems.
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Ultraviolet photochemistry of ethane: implications for the atmospheric chemistry of the gas giants

Chem. Sci., 2020, Advance Article
DOI: 10.1039/D0SC01746A, Edge Article
Open Access
  This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.
Yao Chang, Jiayue Yang, Zhichao Chen, Zhiguo Zhang, Yong Yu, Qingming Li, Zhigang He, Weiqing Zhang, Guorong Wu, Rebecca A. Ingle, Matthew Bain, Michael N. R. Ashfold, Kaijun Yuan, Xueming Yang, Christopher S. Hansen
The vacuum ultraviolet photodissociation dynamics of ethane provide clues for modelling the atmospheric chemistry of the gas giants.
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Determination of protein-ligand binding modes using fast multi-dimensional NMR with hyperpolarization

Chem. Sci., 2020, Accepted Manuscript
DOI: 10.1039/D0SC00266F, Edge Article
Open Access
Yunyi Wang, Jihyun Kim, Christian Hilty
Elucidation of small molecule-protein interactions provides essential information for understanding biological processes such as cellular signaling, as well as for rational drug development. Here, multi-dimensional NMR with sensitivity enhancement by...
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Enlightening advances in polymer bioconjugate chemistry: light-based techniques for grafting to and from biomacromolecules

Chem. Sci., 2020, Advance Article
DOI: 10.1039/D0SC01544J, Perspective
Open Access
Rebecca A. Olson, Angie B. Korpusik, Brent S. Sumerlin
Light-driven synthetic techniques have revolutionized polymer–biomacromolecule conjugation. This Perspective discusses the benefits of photochemistry for polymer–protein ligation and considerations when designing a new light-driven conjugation approach.
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Sequential C–O decarboxylative vinylation/C–H arylation of cyclic oxalates via a nickel-catalyzed multicomponent radical cascade

Chem. Sci., 2020, Advance Article
DOI: 10.1039/D0SC01471K, Edge Article
Open Access
  This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.
Huan Li, Lei Guo, Xiaoliang Feng, Liping Huo, Shengqing Zhu, Lingling Chu
A selective, sequential C–O decarboxylative vinylation/C–H arylation of cyclic alcohol derivatives enabled by visible-light photoredox/nickel dual catalysis has been described.
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Half of FY20 IPOs hold head above water in this selloff, some remain multibaggers

Out of the 15 stocks that got listed in FY 2019-20, seven are still trading above issue prices.




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Sebi extends regulatory approval validity for IPO, rights issue by 6 months

Sebi's observation is necessary for any company to launch public issues.




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Preschool in three cultures revisited : China, Japan, and the United States / Joseph Tobin, Yeh Hsueh, and Mayumi Karasawa

Tobin, Joseph Jay




ul

Photosensitive students and digital media : a survey of educators regarding knowledge and self efficacy / Janene Sproul

Sproul, Janene, author




ul

Academic culture : a student's guide to studying at university / Jean Brick, Maria Herke, Deanna Wong ; editor: Laura Davies

Brick, Jean, author




ul

Creating environments for learning : birth to age eight / Julie Bullard, University of Montana Western

Bullard, Julie, author




ul

Reflective teaching in higher education / Paul Ashwin and [and 10 others]

Ashwin, Paul, 1970-




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Teaching and learning for the twenty-first century : educational goals, policies, and curricula from six nations / Fernando M. Reimers, Connie K. Chung, editors




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Alternatives to privatizing public education and curriculum : Festschrift in honor of Dale D. Johnson / by Daniel Ness & Stephen J. Farenga




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The abandoned generation : democracy beyond the culture of fear / Henry A. Giroux

Giroux, Henry A




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Counternarratives : cultural studies and critical pedagogies in postmodern spaces / Henry Giroux ... [et al.]




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Education and the crisis of public values : challenging the assault on teachers, students, and public education / Henry A. Giroux

Giroux, Henry A, author




ul

Pedagogy and the politics of hope : theory, culture, and schooling : a critical reader / Henry A. Giroux

Giroux, Henry A




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Situation models and children's reading comprehension : what role does visual imagery play? / by Maroulia Katsipis

Katsipis, Maroulia, author




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The skillful teacher : on technique, trust, and responsiveness in the classroom / Stephen D. Brookfield

Brookfield, Stephen, author




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Engaging the six cultures of the academy : revised and expanded edition of the Four cultures of the academy / William H. Bergquist, Kenneth Pawlak

Bergquist, William H




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Das Fernstudium an den Universitäten und Fachhochschulen Australiens / Anno Ortmeier

Ortmeier, Anno




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Teaching language in context / Beverly Derewianka, Pauline Jones

Derewianka, Beverly, 1946- author




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Still learning to think thinking to learn : within the Australian curriculum : planning with a thinking focus / Michael Pohl

Pohl, Michael, author




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The big lies of school reform : finding better solutions for the future of public education / edited by Paul C. Gorski and Kristien Zenkov




ul

You're telling the story : how to develop useful assessments for learning in early childhood / Janet Moles

Moles, Janet




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Living with difference : does multiculturism have a future? / presented by Geoff Gallop

Gallop, Geoff




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Case studies in multiliteracies and inclusive pedagogy : facilitating meaningful literacy learning / Rachel Drewry

Drewry, Rachel, author




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Numeracy and learning difficulties : approaches to teaching and assessment / Peter Westwood

Westwood, Peter S. (Peter Stuart), 1936- author




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The new meaning of educational change / Michael Fullan

Fullan, Michael, author




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Liberating praxis : Paulo Freire's legacy for radical education and politics / by Peter Mayo (University of Malta)

Mayo, Peter, 1955- author




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Developing the curriculum / Peter F. Oliva, William R. Gordon, II

Oliva, Peter F, author




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Developing the curriculum : improved outcomes through systems approaches / William R. Gordon II, Ed.D. (Chief Operations Officer, Retired, Florida virtual School, Orlando, Florida), Rosemarye T. Taylor, Ph.D. (Professor, Educational Leadership, University

Gordon, William, II, author




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Educational psychology : windows on classrooms / Paul Eggen, Don Kauchak

Eggen, Paul D., 1940- author




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Adult education and lifelong learning : theory and practice / Peter Jarvis

Jarvis, Peter, 1937- author




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Reading and learning difficulties : approaches to teaching and assessment / Peter Westwood

Westwood, Peter S. (Peter Stuart), 1936- author