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Salman Visits Eknath Shinde's Home For Ganpati Darshan

Film folk visited Maharashtra Chief Minister Eknath Shinde's residence for Ganpati darshan over the weekend.




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Night Manager Gets Emmy Nomination

'I remember when the offer came in, I was conflicted.'




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When Zeenat Aman Was High!

Here's another nugget from Zeenat Aman's treasure trove of life experiences.





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Memory Zeenat Aman Would Give Up Gold For

'When his laughter died down, Rajji excused himself to make a telephone call.''Twenty minutes later, his most gracious wife Krishnaji was at the door with a handful of gold guineas in her purse.'




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Rise of Economic Nationalism in Emerging Economies and the Influence of Elections

Rise of Economic Nationalism in Emerging Economies and the Influence of Elections Rise of Economic Nationalism in Emerging Economies and the Influence of Elections

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United States, UNESCO, and International Relations through Cultural Heritage

United States, UNESCO, and International Relations through Cultural Heritage United States, UNESCO, and International Relations through Cultural Heritage

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Towards the rejuvenation of Himalayan pasturelands

A collaborative model aims to amalgamate local knowledge with global expertise in the fragile region




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Alternative financial solutions needed for an EV ecosystem 

Will a green line of credit help a net-zero transition in the auto sector?  




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Anatomy of a landfill remediation in progress  

A visit to a dumpsite in Chennai illustrates the solution to the pile up of legacy waste across the country 




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Researchers discover alternate method to study changes during DNA replication process




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Living Library Event: Celebrating International Education | Nov. 21

Link to Notice




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Karnataka Health Minister meets ICMR chief, says KFD vaccine by 2026




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K'taka's economy outpaces national growth despite global headwinds: CM Siddaramaiah�




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Karnataka: CM Siddaramaiah launches door-to-door health service initiative




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Karnataka Film Chamber of Commerce meets CM Siddaramaiah on price issue of movie tickets in multiplexes




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Kannada Rajyotsava celebrated with much fervour in Karnataka; PM, HM, CM greet people




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Implementing Shakti free travel scheme difficult, but won't stop it: Karnataka Transport Minister




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Karnataka bans glass-coated string for flying kites




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No longer one-sided beneficiary of alliance with US: South Korean National Security Advisor




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Nominated posts filled after screening 30,000 applications: Chandrababu Naidu




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PHOTOS: Man City dominate Slovan; Arsenal stun PSG

IMAGES from the Champions League matches played on Tuesday.




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Nations League: England bounce back to down Finland

England enjoyed a 3-1 victory over Finland thanks to goals from Jack Grealish, Trent Alexander-Arnold and Declan Rice.




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Nations League PIX: Italy down Israel; Leweling scores

IMAGES from the UEFA Nations League matches played on Monday.




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Sonata Software secures multi-year deal from Fortune 500 manufacturing company

The client is partnering with Sonata Software to modernise its operations and deliver a homogenous, unified user experience at scale




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Sonata Software optimistic about revenue growth in H2FY25; eyes $1.5 billion revenue by FY27

The company’s international services revenue in the September-ended quarter stood at ₹707.9 crore




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Nature’s beauty




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Electrochemical selective divergent C–H chalcogenocyanation of N-heterocyclic scaffolds

Org. Biomol. Chem., 2024, Advance Article
DOI: 10.1039/D4OB00448E, Communication
Kusum Ucheniya, Pooja Kumari Jat, Amreen Chouhan, Lalit Yadav, Satpal Singh Badsara
An electrochemical direct selective C–H chalcogenocyanation approach for indolizine derivatives under mild conditions has been described.
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Click synthesis of dendronized malonates for the preparation of amphiphilic dendro[60]fullerenes

Org. Biomol. Chem., 2024, Advance Article
DOI: 10.1039/D3OB01986A, Paper
Carlos Cruz-Hernández, Perla Y. López-Camacho, Gustavo Basurto-Islas, Aaron Rojas, Patricia Guadarrama, Melchor Martínez-Herrera
Click chemistry is a valuable methodology for obtaining dendronized malonate derivatives to derivatize C60 using the Bingel–Hirsch reaction.
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Copper catalyzed dehydrogenative cyclization, alkenylation towards dihydroquinolinones

Org. Biomol. Chem., 2024, Accepted Manuscript
DOI: 10.1039/D4OB00134F, Paper
Pari Keerthana, Fazlur-Rahman Nawaz Khan
An efficient copper-catalysized one-pot sequential synthesis of alkenylated quinolinyldihydroquinolinones is reported utilizing ketones, 1,3-cyclohexanediones, and benzyl alcohols via dehydrogenative cyclisation, followed by alkenylation. This highly straightforward method provides a mild...
The content of this RSS Feed (c) The Royal Society of Chemistry




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On the mechanism of carboxylate elimination from carbohydrate monoester-derived radicals

Org. Biomol. Chem., 2024, Advance Article
DOI: 10.1039/D4OB00241E, Communication
Open Access
  This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.
Julia A. Turner, Hendrik Zipse, Mark S. Taylor
Computational analysis of the HAT-induced expulsion of carboxylic acids from monoacylated pyranosides implicates concerted elimination through a hydrogen-bonded transition state.
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Generation of sulfones utilizing β-sulfinyl esters as masked aryl sulfinates under redox-neutral conditions

Org. Biomol. Chem., 2024, Advance Article
DOI: 10.1039/D4OB00238E, Communication
Yixin Zhang, Zhu Yang, Hongjun Yang, Xuefeng Li, Lu Yang
A method for generation of SVI sulfones from β-sulfinyl esters (SIV) under transition-metal-free non-oxidative mild conditions is presented.
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Photoinduced decatungstate-catalyzed C(sp3)–H thioetherification by sulfinate salts

Org. Biomol. Chem., 2024, Advance Article
DOI: 10.1039/D4OB00394B, Paper
Pengcheng Li, Jia-Lin Tu, Ao-Men Hu, Lin Guo, Chao Yang, Wujiong Xia
A visible light photoinduced decatungstate-catalyzed C(sp3)–H thioetherification of hydrocarbons by sodium sulfite is herein reported.
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HFIP-mediated C-3-alkylation of indoles and synthesis of indolo[2,3-b]quinolines & related natural products

Org. Biomol. Chem., 2024, Advance Article
DOI: 10.1039/D4OB00414K, Paper
Auqib Rashid, Waseem I. Lone, Preeti Dogra, Showkat Rashid, Bilal A. Bhat
An expeditious metal free C-3 alkylation of indoles and its NIS-mediated deviation to indolo[2,3-b]quinolines is reported. Applications of these strategies in accessing bioactive natural products have also been demonstrated.
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Copper-catalyzed ortho-thiocyanation of aromatic amines

Org. Biomol. Chem., 2024, Advance Article
DOI: 10.1039/D4OB00137K, Communication
Monak Patel, Nitish Kumar, Hussain Bhukya, Bharatkumar Z. Dholakiya, Togati Naveen
Here, we described an efficient ortho- C(sp2)-H thiocyanation of anilines for the synthesis of aryl thiocyanates. This protocol tolerates a variety of aromatic amines to provide the desired products in good to excellent yields.
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Chemoenzymatic total synthesis of rotigotine via IRED-catalyzed reductive amination

Org. Biomol. Chem., 2024, Advance Article
DOI: 10.1039/D4OB00072B, Communication
Dongyu Tang, Yaqing Ma, Jinping Bao, Shushan Gao, Shuli Man, Chengsen Cui
An engineered imine reductase (IRED) was developed specifically for 2-tetralone substrate, and utilized in the total synthesis of rotigotine.
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Synthesis of alkenylphosphine oxides via Tf2O promoted addition–elimination of ketones and secondary phosphine oxides

Org. Biomol. Chem., 2024, Advance Article
DOI: 10.1039/D4OB00318G, Communication
Jiangkai Ma, Lianjie Wang, Anjiang Qiao, Zhongxian Li, Fengqian Zhao, Junliang Wu
An efficient method for the synthesis of alkenylphosphine oxides via the addition-elimination of SPOs to ketones has been developed. The reaction exhibits good yields and compatibility. Several conversions have also proven the value of this method.
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Palladium-catalyzed (Z)-selective allylation of phosphine oxides with vinylethylene carbonates to construct phosphorus allyl alcohols

Org. Biomol. Chem., 2024, 22,3068-3072
DOI: 10.1039/D4OB00354C, Paper
Hua Huang, Yi-Qi Wu, Lu-Yao Han, Lu Jiang, Zhuo-Zhuo Zhang, Xiang Zhang, Bo Han, Wei Huang, Jun-Long Li
A general and efficient method for the highly stereoselective synthesis of (Z)-phosphorus allylalcohols has been developed using the Pd-catalyzed cross-coupling of phosphine oxides with vinylethylene carbonates.
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Additive-free oxychlorination of unsaturated C–C bonds with tert-butyl hypochlorite and water

Org. Biomol. Chem., 2024, 22,3080-3085
DOI: 10.1039/D4OB00003J, Paper
Duyi Shen, Chaoyue Sun, Yun Han, Zhen Luo, Ting Ren, Qin Zhang, Wenting Huang, Jianru Xie, Ying Jia, Mianran Chao
A facile oxychlorination of various alkynes and alkenes with tBuOCl as an alternative chlorine source and H2O as a green oxygen source.
The content of this RSS Feed (c) The Royal Society of Chemistry




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Nickel-catalysed regio- and stereoselective hydrocyanation of alkynoates and its mechanistic insights proposed by DFT calculations

Org. Biomol. Chem., 2024, Advance Article
DOI: 10.1039/D4OB00380B, Communication
Shigeru Arai, Koichi Nakazawa, Xiao-Fei Yang, Masaya Nakajima, Shinji Harada, Atsushi Nishida
This work discloses the origin of regio- and stereoselectivity of hydrocyanation of alkynoates.
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Exploring the mechanism of the reductive amination of acetophenones via Borch approach: the role of the acid catalyst

Org. Biomol. Chem., 2024, Accepted Manuscript
DOI: 10.1039/D4OB00160E, Paper
João Pedro Albuquerque Souza, Amanda Krauskopf Jacobs, Leandro Piovan, Renan Borsoi Campos
The energetic viability of several mechanistic variations of the reductive amination of acetophenones via the Borch approach was reexamined through density functional theory calculations. The crucial involvement of the acid...
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Discovery of selective monosaccharide receptors via dynamic combinatorial chemistry

Org. Biomol. Chem., 2024, Advance Article
DOI: 10.1039/D4OB00015C, Communication
Open Access
  This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.
Miguel Alena-Rodriguez, Marcos Fernandez-Villamarin, Ignacio Alfonso, Paula M. Mendes
An effective workflow to discover selective saccharide receptors by combining dynamic combinatorial chemistry with isothermal titration calorimetry and NMR.
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Isothiocyanates: Happy-Go-Lucky Reagents in Organic Synthesis

Org. Biomol. Chem., 2024, Accepted Manuscript
DOI: 10.1039/D4OB00281D, Review Article
Bubul Das, Anjali Dahiya, Bhisma K Patel
: Owing to their unique structural features, isothiocyanates (ITCs) are a class of highly useful and inimitable reagents as the N=C=S group serves both as electrophile and nucleophile in organic...
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Natural products from human microbiome: an emergent frontier in organic synthesis and drug discovery

Org. Biomol. Chem., 2024, Accepted Manuscript
DOI: 10.1039/D4OB00236A, Review Article
Goverdhan Mehta, Saumitra Sengupta, Srihari Pabbaraja
Often referred to as “second genome”, human microbiome is at the epicenter of a complex inter-habitat biochemical network, such as the “gut-brain axis”, which have emerged as significant determinant of...
The content of this RSS Feed (c) The Royal Society of Chemistry




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N-Functionalization of beta-aminophosphonates; Cytotoxic effect of the new derivatives

Org. Biomol. Chem., 2024, Accepted Manuscript
DOI: 10.1039/D4OB00243A, Paper
György Keglevich, Petra Regina Varga, Emőke Dinnyési, Zsuzsanna Szalai, Szilvia Bősze, Rita Oláhné Szabó, Laszlo Drahos, Konstantin Karaghiosoff
Beta-Aminophosponates obtained by the Michael addition of primary amines to the double bond of diethyl vinylphosphonate proved to be suitable starting materials (amine components) in the Kabachnik–Fields reaction with formaldehyde...
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Visible light-driven photocatalytic sulfonative oxidation of benzyl secondary amines

Org. Biomol. Chem., 2024, Accepted Manuscript
DOI: 10.1039/D4OB00348A, Paper
Yong-Xiang Lü, Xinqian Wang, Ying-Ming Pan, Keyume Ablajan
A method for the α-oxidation and sulfonation of benzyl secondary amines was developed utilizing Ir(III) or Eosin Y as the photocatalyst in the presence of O2 as a green oxidant....
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Karnataka government plans to start 11 medical colleges under contentious PPP model

As of now, the State has 22 government medical colleges in 22 districts while 11 others have no government medical colleges; the PPP model however has been criticised by some experts




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WHO says ‘intense bombardment’ halts Gaza polio vaccinations

The U.N. health body said it had been “compelled to postpone” the bid to give 119,279 children in northern Gaza a second vaccine dose due to the escalating violence




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Trachoma eliminated as a public health problem in India; what next?

The achievement marks a significant public health victory and has profound economic implications. Trachoma’s impact, through blindness and visual impairment, results in an estimated economic loss of $2.9 to 5.3 billion annually due to reduced productivity




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National Mental Health Festival 2024 kicks off in Bengaluru