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Unexpected link between nickel toxicity, cholesterol levels found

In a new study, fungi that lacked the Sre1 protein were found to be highly sensitive to nickel; the gene that encodes for this protein is conserved in all animals, including humans




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Selectively controlled synthesis of diethyl carbonate and methyl ethyl carbonate via transesterification of dimethyl carbonate over a KATriz/Al2O3 catalyst

Catal. Sci. Technol., 2024, Advance Article
DOI: 10.1039/D4CY00979G, Paper
Open Access
Peixue Wang, Shimin Liu, Xinjiang Cui, Feng Shi
Effectively synthesis of methyl ethyl carbamate from dimethyl carbonate and ethanol using 14 wt% KATriz/Al2O3 in fixed bed mode.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry




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Collagen / polyester-polyurethane porous scaffolds for use in meniscal repair

Biomater. Sci., 2024, Accepted Manuscript
DOI: 10.1039/D4BM00234B, Paper
Open Access
Gaëlle Savin, Sylvain Caillol, Audrey Bethry, Eric Rondet, Michel Assor, Ghislain David, Benjamin Nottelet
Focusing on the regeneration of damaged knee meniscus, we propose a hybrid scaffold made of a poly(ester-urethane) (PEU) and collagen that combines suitable mechanical properties and degradability with enhanced biological...
The content of this RSS Feed (c) The Royal Society of Chemistry




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The Bicester Collection’s Unlock Her Future Prize aims to empower women entrepreneurs

After West Asia, North Africa, and Latin America — where seaweed textile picked up the top prize — the newest initiative empowering women entrepreneurs is heading to South Asia 




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London’s fishy fireball and festering fatberg




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Biodegradable polymers: from synthesis methods to applications of lignin-graft-polyester

Green Chem., 2024, 26,10774-10803
DOI: 10.1039/D4GC03558E, Tutorial Review
Open Access
Sundol Kim, Hoyong Chung
Biodegradable lignin-based grafted polyesters have wide range of applications.
The content of this RSS Feed (c) The Royal Society of Chemistry




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Electrochemistry-enabled Rh-catalyzed regioselective [4 + 1] and [4 + 2] cycloaddition of benzoic acid with alkynyl esters/amides

Green Chem., 2024, 26,10996-11002
DOI: 10.1039/D4GC03753G, Paper
Wei-Jung Chiu, Chung-Ming Sun
The reaction of benzoic acids with alkynyl esters/amides in the presence of a Rh-catalyst and AcOH as an additive to give phthalides by [4 + 1] annulation. In contrast, the additive NaOAc exclusively affords isocoumarins through the [4 + 2] pathway.
The content of this RSS Feed (c) The Royal Society of Chemistry




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A solvent-free, self-emulsified and heat-responsive polyester coating enables chemically-recyclable and fire-safe PET foam

Green Chem., 2024, Advance Article
DOI: 10.1039/D4GC04531A, Paper
Bei-Bei Zhang, Li-Xia Fan, Lin Chen, Xiu-Li Wang, Yu-Zhong Wang
This work implements a state-of-the-art strategy to simultaneously achieve use performance and future recycling, which will greatly benefit the green sustainable circular economy for wind turbine blades.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry




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CO2 catalyzed recycling of polyester and polycarbonate plastics

Green Chem., 2024, Advance Article
DOI: 10.1039/D4GC04782F, Paper
Open Access
Qiao Zhang, Nan Wang, Chenyang Hu, Peng-Yuan Li, Fu-Quan Bai, Xuan Pang, Xuesi Chen, Xianhong Wang
CO2 was found to be an efficient catalyst for depolymerizing common waste polyesters and polycarbonates via alcoholysis, yielding valuable organic molecules. CO2 was considered a Lewis acid–base pair, activating both polymers and alcohol.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry




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Catalyst free PET and PEF polyesters using a new traceless oxalate chain extender

Green Chem., 2024, 26,11182-11195
DOI: 10.1039/D4GC02791D, Paper
Open Access
  This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.
Kevin van der Maas, Daniel H. Weinland, Robert-Jan van Putten, Bing Wang, Gert-Jan M. Gruter
When producing PET the metal catalyst (typically Sb) remains in the polymer. This raises concerns as our food and the air we breathe is contaminated with PET microplastics. Here we report the production of metal-free PET using a small amount of DGO.
The content of this RSS Feed (c) The Royal Society of Chemistry




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Biomass-derived polyol esters as sustainable phase change materials for renewable energy storage

Green Chem., 2024, 26,11259-11271
DOI: 10.1039/D4GC03460K, Paper
Open Access
  This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.
Magdalena Gwóźdź, Marta Markiewicz, Stefan Stolte, Anna Chrobok, David R. Turner, Karolina Matuszek, Alina Brzęczek-Szafran
Innovative thermal battery technology has the capability to revolutionize the renewable energy storage market.
The content of this RSS Feed (c) The Royal Society of Chemistry




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Converting waste PET into dimethyl terephthalate and diverse boronic esters under metal-free conditions

Green Chem., 2024, 26,11132-11139
DOI: 10.1039/D4GC03358B, Communication
Minghao Zhang, Yunkai Yu, Zhuo Wang, Shaoyu Zhang, Xiong Gao, Jiaming Liu, Jing Li, Weixiang Wu, Qingqing Mei
An ionic liquid-catalyzed metal-free approach was proposed to upcycle waste PET into dimethyl terephthalate and boronic esters, facilitated by multiple hydrogen bonds.
The content of this RSS Feed (c) The Royal Society of Chemistry




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With four losses on the bounce for Manchester City, is it just a pause for breath for Pep Guardiola or a cause for worry?




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‘Ready for new challenge,’ says new Manchester United coach Ruben Amorim




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Manchester United and Ruud van Nistelrooy part ways after Dutchman’s interim coaching stint ends




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‘Please doubt us, feel welcome to do so’: Manchester City’s Ruben Dias to critics after club’s recent rough patch




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Manchester United captain Bruno Fernandes rescues fainting passenger on flight




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Western Digital Is Offering A Rs 75,000 Scholarship To...

Western Digital is offering a one-time scholarship of up to Rs 75,000 to persons with disabilities and transgender students pursuing graduation, post-graduation and PhD degrees in STEM-related fields.




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Time For India To Revisit Western Alliances

It's time India re-visited its Western alliances for the attitude and approach that the West reserves for the nation when it comes to security cooperation of the kind that they might not have visualised outside of China, India's bug-bear, asserts N Sathiya Moorthy.




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Western Digital Is Offering A Rs 75,000 Scholarship To...

Western Digital is offering a one-time scholarship of up to Rs 75,000 to persons with disabilities and transgender students pursuing graduation, post-graduation and PhD degrees in STEM-related fields.




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EPL PIX: United thrash Leicester; Ipswich stun Spurs

IMAGES from the English Premier League matches played on Sunday.




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Tottenham join Manchester United and Chelsea as Premier League clubs target Sergej Milinkovic-Savic 

Tottenham have become the latest Premier League club to show interest in signing Lazio star Sergej Milinkovic-Savic,The Serbia international is under contract at the Stadio Olimpico until 2024.




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Tottenham join Manchester United and Chelsea as Premier League clubs target Sergej Milinkovic-Savic 

Tottenham have become the latest Premier League club to show interest in signing Lazio star Sergej Milinkovic-Savic,The Serbia international is under contract at the Stadio Olimpico until 2024.




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ML 3.8 WESTERN IRAN

Magnitude  ML 3.8
Region  WESTERN IRAN
Date time  2020-05-10 08:21:08.4 UTC
Location  33.76 N ; 48.12 E
Depth  13 km




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Protesters want Alberta to reopen economy more quickly

Dozens of protesters descended on the legislature Saturday afternoon, calling for a quicker reopening of the Alberta economy.




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Dog stolen from foster home in Chestermere, Alta. found safe

Wera, a four-year-old terrier cross, has found her way home to a Calgary-care organization after fraudsters tricked the dog's foster family.




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Protesters demand end to Manitoba's COVID-19 lockdown measures

A crowd descended on the Manitoba Legislature Building Saturday afternoon, demanding an end to the COVID-19 quarantine.




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Managing the Emergence of Rising Powers: A Western Response

Research Event

22 May 2014 - 5:00pm to 6:15pm

Chatham House, London

Event participants

Trine Flockhart, Senior Fellow, Transatlantic Academy
Patrick W Quirk, Fellow, Transatlantic Academy
Chair: Dr Leslie Vinjamuri, Senior Lecturer in International Relations, SOAS

This event will present the findings of the Transatlantic Academy’s new report, Liberal Order in a Post-Western World, which examines the future of international liberal order in a world shaped by the rise of emerging powers and a transatlantic community dealing with internal challenges. Produced by collaboration between scholars from Europe and North America, it recommends ways to build an enduring rules-based order for the 21st century.

Department/project




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Glucocerebrosidases catalyze a transgalactosylation reaction that yields a newly-identified brain sterol metabolite, galactosylated cholesterol [Glycobiology and Extracellular Matrices]

β-Glucocerebrosidase (GBA) hydrolyzes glucosylceramide (GlcCer) to generate ceramide. Previously, we demonstrated that lysosomal GBA1 and nonlysosomal GBA2 possess not only GlcCer hydrolase activity, but also transglucosylation activity to transfer the glucose residue from GlcCer to cholesterol to form β-cholesterylglucoside (β-GlcChol) in vitro. β-GlcChol is a member of sterylglycosides present in diverse species. How GBA1 and GBA2 mediate β-GlcChol metabolism in the brain is unknown. Here, we purified and characterized sterylglycosides from rodent and fish brains. Although glucose is thought to be the sole carbohydrate component of sterylglycosides in vertebrates, structural analysis of rat brain sterylglycosides revealed the presence of galactosylated cholesterol (β-GalChol), in addition to β-GlcChol. Analyses of brain tissues from GBA2-deficient mice and GBA1- and/or GBA2-deficient Japanese rice fish (Oryzias latipes) revealed that GBA1 and GBA2 are responsible for β-GlcChol degradation and formation, respectively, and that both GBA1 and GBA2 are responsible for β-GalChol formation. Liquid chromatography–tandem MS revealed that β-GlcChol and β-GalChol are present throughout development from embryo to adult in the mouse brain. We found that β-GalChol expression depends on galactosylceramide (GalCer), and developmental onset of β-GalChol biosynthesis appeared to be during myelination. We also found that β-GlcChol and β-GalChol are secreted from neurons and glial cells in association with exosomes. In vitro enzyme assays confirmed that GBA1 and GBA2 have transgalactosylation activity to transfer the galactose residue from GalCer to cholesterol to form β-GalChol. This is the first report of the existence of β-GalChol in vertebrates and how β-GlcChol and β-GalChol are formed in the brain.




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Answers to prayer in Manchester

With OM Lifehope, Andrea works with a local church and growing church plant, providing her with many opportunities to build relationships with locals.




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Cockerill: I helped set up move to Leicester

EDINBURGH coach Richard Cockerill has explained that he played a part in Matt Scott’s move to Leicester Tigers after deciding he could not afford to keep the former Scotland centre.




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The Sequester and Its Impact on US Government Funding for Renewable Energy Projects

Mandatory spending cuts triggered by the March 1st sequester (automatic spending cuts) in the U.S. are being felt across the renewable energy sector sparking fears that reduced federal investment could curtail research, development and commercialization of new renewable energy technologies.




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Nigeria: Manchester United - Odion Ighalo se montre prudent en ce qui concerne son avenir

Pr�t� � Manchester United par le Shanghai...




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Coronavirus spread in Western Cape in need of urgent intervention - Dhlomo

Cape Town - Health Minister Zweli Mkhize on Saturday descended on the Western Cape as pressure mounted on the national government to intervene in the coastal province that has recorded more than half of the country’s Covid-19 infections. This after health portfolio committee chairperson Sibongiseni Dhlomo had called for urgent intervention in the spread of the virus while the ANC wanted a return to level 5 of lockdown. Speaking at a press briefing in Cape Town on Saturday, Mkhize said the spread of the virus in the Western Cape was not different from other provinces. He said that the national government would provide more support, such as further training of health-care workers and...




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Manchester United not happy with De Gea

Manchester United are not happy with the performance of their first-choice goalkeeper, David de Gea. This claim was made by respected football expert and journalist, Duncan Castles. According to Castles, Man United believe they made a huge mistake by signing a lucrative long-term contract last year with De Gea and would be glad to offload […]

Manchester United not happy with De Gea




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Covid-19 in Western Cape: Province now has 3309 active cases

More than 1600 people have now recovered from the Covid-19 in the Western Cape, the provincial government said on Saturday.




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Coronavirus spread in Western Cape in need of urgent intervention - Dhlomo

Health Minister Zweli Mkhize on Saturday descended on the Western Cape as pressure mounted on the national government to intervene in the coastal province.




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Indian protesters carry dead bodies into gas leak plant

VISAKHAPATNAM, India: Angry protesters carrying dead bodies stormed an Indian chemical plant on Saturday to demand the facility's closure after a toxic gas leak that killed 12 people days...

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Indian protesters carry dead bodies into gas leak plant

Visakhapatnam, India: Angry protesters carrying dead bodies stormed an Indian chemical plant on Saturday to demand the facility’s closure after a toxic gas leak that killed 12 people days earlier.Thursday’s pre-dawn accident in the industrial port city of Visakhapatnam injured hundreds...




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Indian protesters carry dead bodies into gas leak plant

VISAKHAPATNAM, India: Angry protesters carrying dead bodies stormed an Indian chemical plant on Saturday to demand the facility’s closure after a toxic gas leak that killed 12 people days earlier.Thursday’s pre-dawn accident in the industrial port city of Visakhapatnam injured hundreds...




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Iraq's new govt reaches out to October protesters

Iraq's new government promised Saturday to release demonstrators arrested during mass protests that erupted in October and pledged justice and compensation to relatives of over 550 people killed during that unrest.




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Darrell Issa Appears to Flee to Building Roof to Avoid Protesters

Rep. Darrell Issa (R-Calif.) was seen taking refuge on the roof of his office building in Vista, California, Tuesday, taking photos of angry constituents who had gathered below to protest the congressman's voting record. The incident comes before a much-anticipated town hall meeting this Saturday at San Juan Hills High School, where the nine-term congressman is expected to face a hostile crowd because of his support for various Trump administration policies, including the Republican plan to repeal and replace Obamacare.

Democrat Mike Levin, an environmental lawyer who recently announced his bid to challenge Issa in 2018, shared an image of the congressman appearing to avoid demonstrators on social media, where it was roundly mocked.

Others saw his retreating to a rooftop as reminiscent of Michael Scott, Steve Carrell's character in The Office who memorably took to the roof in the episode titled "Safety Training."

Issa, on the other hand, described his trip to the roof a bit differently. Shortly after the criticism, he took to Twitter to offer this narrative. We recommend zooming in to take a closer look at the signs:

For more on Levin and the fight to defeat Issa, the richest man in Congress, head to our profile here.




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Hashtag Trending – Facebook bans anti-lockdown protesters; Amazon VP condemns Amazon, quits; New Apple Macbooks

Anti-quarantine protesters jumped onto other social platforms after being shut down by Facebook, Amazon Vice President Tim Bray said Amazon is designed to create a climate of fear and quits the company, Apple releases new MacBook 13 with an improved keyboard and more storage.   Anti-quarantine protesters are being kicked off Facebook and quickly finding…





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What Governments In The Western Hemisphere Are Getting Right — And Wrong

We look at nations in our hemisphere, from Canada to Argentina, to see which governments are succeeding — and which are not — in keeping coronavirus infections down.




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Covid 19 coronavirus: Anti-lockdown protesters clash with police in Melbourne

Dozens of anti-lockdown protesters swarmed the steps of Victoria's Parliament House today with several people being arrested.More than 200 people flouted social distancing restrictions to furiously demand an end to the coronavirus...




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Marc Jurado hints at Manchester United signing Joe Hugill in double wonderkid deal

Manchester United have embarked on an aggressive recruitment drive to sign some of Europe's top young players - and they appear to have landed two in one week.




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Armed Protesters Order Food at Subway, AT-4 Rocket Launcher Included

A group of protesters busted through the doors of a Subway with their guns blazing -- but it wasn't to shoot the place up ... they were just hangry for some footlongs, apparently. A photojournalist for the News & Observer in Raleigh, NC…




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What Governments In The Western Hemisphere Are Getting Right — And Wrong

We look at nations in our hemisphere, from Canada to Argentina, to see which governments are succeeding — and which are not — in keeping coronavirus infections down.




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Protesters gather outside Mayor Garcetti's Hancock Park residence to protest health restrictions

At least 100 protesters gathered outside the residence of Los Angeles Mayor Eric Garcetti, with marchers calling for the economy to reopen and condemning the health orders enacted in response to the coronavirus outbreak.