BIOVIA Direct 2020

With Windows 2000 Microsoft introduced the inheritance of access rights and new Win32-API functions like SetNamedSecurityInfo() which handle the inheritance. SetNamedSecurityInfo() but has a serious bug: it applies inheritable ACEs from a PARENT object to a target object even if it must not do so, indicated by the flags SE_DACL_PROTECTED and/or SE_SACL_PROTECTED in the security descriptor of the target object.

Oracle Java versions prior to 7u25 suffer from an invalid array indexing vulnerability that exists within the native storeImageArray() function inside jre/bin/awt.dll. This exploit code demonstrates remote code execution by popping calc.exe. It was obtained through the Packet Storm Bug Bounty program.

Oracle Java versions prior to 7u25 suffer from an invalid array indexing vulnerability that exists within the native storeImageArray() function inside jre/bin/awt.dll. This vulnerability allows for remote code execution. User interaction is required for this exploit in that the target must visit a malicious page or open a malicious file. This finding was obtained through the Packet Storm Bug Bounty program.

The IntegerInterleavedRaster.verify() method in Oracle Java versions prior to 7u25 is vulnerable to a signed integer overflow that allows bypassing of "dataOffsets[0]" boundary checks. This exploit code demonstrates remote code execution by popping calc.exe. It was obtained through the Packet Storm Bug Bounty program.

The IntegerInterleavedRaster.verify() method in Oracle Java versions prior to 7u25 is vulnerable to a signed integer overflow that allows bypassing of "dataOffsets[0]" boundary checks. This vulnerability allows for remote code execution. User interaction is required for this exploit in that the target must visit a malicious page or open a malicious file. This finding was purchased through the Packet Storm Bug Bounty program.

The BytePackedRaster.verify() method in Oracle Java versions prior to 7u25 is vulnerable to a signed integer overflow that allows bypassing of "dataBitOffset" boundary checks. This exploit code demonstrates remote code execution by popping calc.exe. It was obtained through the Packet Storm Bug Bounty program.

The BytePackedRaster.verify() method in Oracle Java versions prior to 7u25 is vulnerable to a signed integer overflow that allows bypassing of "dataBitOffset" boundary checks. This vulnerability allows for remote code execution. User interaction is required for this exploit in that the target must visit a malicious page or open a malicious file. This finding was purchased through the Packet Storm Bug Bounty program.

The ByteComponentRaster.verify() method in Oracle Java versions prior to 7u25 is vulnerable to a memory corruption vulnerability that allows bypassing of "dataOffsets[]" boundary checks. This exploit code demonstrates remote code execution by popping calc.exe. It was obtained through the Packet Storm Bug Bounty program.

The ByteComponentRaster.verify() method in Oracle Java versions prior to 7u25 is vulnerable to a memory corruption vulnerability that allows bypassing of "dataOffsets[]" boundary checks. This vulnerability allows for remote code execution. User interaction is required for this exploit in that the target must visit a malicious page or open a malicious file. This finding was purchased through the Packet Storm Bug Bounty program.

The ShortComponentRaster.verify() method in Oracle Java versions prior to 7u25 is vulnerable to a memory corruption vulnerability that allows bypassing of "dataOffsets[]" boundary checks when the "numDataElements" field is 0. This exploit code demonstrates remote code execution by popping calc.exe. It was obtained through the Packet Storm Bug Bounty program.

The ShortComponentRaster.verify() method in Oracle Java versions prior to 7u25 is vulnerable to a memory corruption vulnerability that allows bypassing of "dataOffsets[]" boundary checks when the "numDataElements" field is 0. This vulnerability allows for remote code execution. User interaction is required for this exploit in that the target must visit a malicious page or open a malicious file. This finding was purchased through the Packet Storm Bug Bounty program.

Oracle WebLogic version 12.1.2.0 RMI registry UnicastRef object java deserialization remote code execution exploit.

A difficult to exploit heap-based buffer overflow in setuid root whodo and w binaries distributed with Solaris allows local users to corrupt memory and potentially execute arbitrary code in order to escalate privileges.

pytacle is a tool inspired by tentacle. It automates the task of sniffing GSM frames of the air, extracting the key exchange, feeding kraken with the key material and finally decode/decrypt the voice data. All You need is a USRP (or similar) to capture the GSM band and a kraken instance with the berlin tables (only about 2TB).

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The country's lockdown model is being lauded by the WHO, but it's a unique case whose death rate is much worse than its neighbors.

Attacking midfielder uses the myriad setbacks he has experienced in his career as motivation to succeed in life.

The story of how gin and tonic came together fizzes with adventure, discovery, imperial ambition, biopiracy and a generous splash of fake news

Title: Training Programs Protect Young Athletes From ACL Tears: Report
Category: Health News
Created: 4/28/2014 9:35:00 AM
Last Editorial Review: 4/28/2014 12:00:00 AM

Paclitaxel has been considered to cause OATP1B-mediated drug-drug interactions at therapeutic doses; however, its clinical relevance has not been demonstrated. This study aimed to elucidate in vivo inhibition potency of paclitaxel against OATP1B1 and OATP1B3 using endogenous OATP1B biomarkers. Paclitaxel is an inhibitor of OATP1B1 and OATP1B3, with K_i of 0.579 ± 0.107 and 5.29 ± 3.87 μM, respectively. Preincubation potentiated its inhibitory effect on both OATP1B1 and OATP1B3, with K_i of 0.154 ± 0.031 and 0.624 ± 0.183 μM, respectively. Ten patients with non–small cell lung cancer who received 200 mg/m² of paclitaxel by a 3-hour infusion were recruited. Plasma concentrations of 10 endogenous OATP1B biomarkers—namely, coproporphyrin I, coproporphyrin III, glycochenodeoxycholate-3-sulfate, glycochenodeoxycholate-3-glucuronide, glycodeoxycholate-3-sulfate, glycodeoxycholate-3-glucuronide, lithocholate-3-sulfate, glycolithocholate-3-sulfate, taurolithocholate-3-sulfate, and chenodeoxycholate-24-glucuronide—were determined in the patients with non–small cell lung cancer on the day before paclitaxel administration and after the end of paclitaxel infusion for 7 hours. Paclitaxel increased the area under the plasma concentration-time curve (AUC) of the endogenous biomarkers 2- to 4-fold, although a few patients did not show any increment in the AUC ratios of lithocholate-3-sulfate, glycolithocholate-3-sulfate, and taurolithocholate-3-sulfate. Therapeutic doses of paclitaxel for the treatment of non–small cell lung cancer (200 mg/m²) will cause significant OATP1B1 inhibition during and at the end of the infusion. This is the first demonstration that endogenous OATP1B biomarkers could serve as surrogate biomarkers in patients.

An infamous sex predator dubbed "the Notting Hill rapist" has been recommended for transfer to an open prison.

Shadow, a tech developer started by veterans of Hillary Clinton's 2016 presidential run, built the app being blamed for delaying Iowa Democratic caucus results.

Canadian Music Week has abandoned plans for a 2020 festival after initially postponing the spring event due to the COVID-19 pandemic.

Queensland is the first state to sign off on the planned May 28 return of the NRL and the Prime Minister hopes Border Force will allow the NZ Warriors into Australia shortly.

The new White House communications team is scrambling to keep Trump on TV but limit his ability to offer dangerous medical advice. The goal is to show him as a leader and push his reelection message. The problem is that Trump almost certainly will sabotage the plan.

After conducting a careful investigation of the proposed transaction between Oracle and Sun, the Department’s Antitrust Division concluded that the merger is unlikely to be anticompetitive.

The United States has intervened and filed a complaint under the False Claims Act against Oracle Corporation and Oracle America Inc.

Oracle America Inc. has agreed to pay the United States $46 million to settle claims that Sun Microsystems Inc., a corporation that merged with Oracle in 2010, submitted false claims and caused others to submit false claims to the General Services Administration and other federal agencies.

Oracle Corp. and Oracle America Inc. have agreed to pay $199.5 million plus interest for failing to meet their contractual obligations to the General Services Administration.

The Scotts Miracle-Gro Company, a producer of pesticides for commercial and consumer lawn and garden uses, was sentenced today in federal district court in Columbus, Ohio, to pay a $4 million fine and perform community service for eleven criminal violations of the Federal Insecticide, Fungicide and Rodenticide Act, which governs the manufacture, distribution, and sale of pesticides.

Louis Daniel Smith, 42, and Karis Delong, 38, both of Ashland, Ore., were charged with defrauding regulators and suppliers in a scheme to manufacture and sell industrial bleach as a cure for numerous illnesses, including arthritis, cancer and the seasonal flu.