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Reducing Integration Barriers Facing Foreign-Trained Immigrants: Policy and Practice Lessons from Across the United States

Marking the release of a report on the barriers foreign-trained high-skilled immigrants face in the United States, this webinar examines programs and initiatives that assist with credential recognition, employment, and relicensure, as well as recent policy developments. Discussants review recommendations for community-based organizations, employers, and policymakers to expand successful efforts aimed at preventing brain waste. 




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Prosciutto and cheese croquettes

75g butter 75g (1/2 cup) plain flour 500ml (2 cups) milk 75g finely grated parmesan 1 small red onion, finely diced 200g prosciutto, finely chopped 2 tablespoons chopped fresh parsley 3 eggs, lightly whisked 1 cup plain flour 270g (3 cups) dried breadcrumbs Vegetable oil, to deep-fry





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Brussels Sprout Caesar with Croutons, Borlotti Beans and Sunflower Seeds

This recipe features on Foodie Tuesday, a weekly segment on 774 Drive with Raf Epstein, 3.30PM, shared by Hetty McKinnon, founder of Surry Hills community kitchen Arthur Street Kitchen and author of 'Neighbourhood'.




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Microvascular and Cardiovascular Outcomes According to Renal Function in Patients Treated With Once-Weekly Exenatide: Insights From the EXSCEL Trial

OBJECTIVE

To evaluate the impact of once-weekly exenatide (EQW) on microvascular and cardiovascular (CV) outcomes by baseline renal function in the Exenatide Study of Cardiovascular Event Lowering (EXSCEL).

RESEARCH DESIGN AND METHODS

Least squares mean difference (LSMD) in estimated glomerular filtration rate (eGFR) from baseline between the EQW and placebo groups was calculated for 13,844 participants. Cox regression models were used to estimate effects by group on incident macroalbuminuria, retinopathy, and major adverse CV events (MACE). Interval-censored time-to-event models estimated effects on renal composite 1 (40% eGFR decline, renal replacement, or renal death) and renal composite 2 (composite 1 variables plus macroalbuminuria).

RESULTS

EQW did not change eGFR significantly (LSMD 0.21 mL/min/1.73 m2 [95% CI –0.27 to 0.70]). Macroalbuminuria occurred in 2.2% of patients in the EQW group and in 2.5% of those in the placebo group (hazard ratio [HR] 0.87 [95% CI 0.70–1.07]). Neither renal composite was reduced with EQW in unadjusted analyses, but renal composite 2 was reduced after adjustment (HR 0.85 [95% CI 0.74–0.98]). Retinopathy rates did not differ by treatment group or in the HbA1c-lowering or prior retinopathy subgroups. CV outcomes in those with eGFR <60 mL/min/1.73 m2 did not differ by group. Those with eGFR ≥60 mL/min/1.73 m2 had nominal risk reductions for MACE, all-cause mortality, and CV death, but interactions by renal function group were significant for only stroke (HR 0.74 [95% CI 0.58–0.93]; P for interaction = 0.035) and CV death (HR 1.08 [95% CI 0.85–1.38]; P for interaction = 0.031).

CONCLUSIONS

EQW had no impact on unadjusted retinopathy or renal outcomes. CV risk was modestly reduced only in those with eGFR ≥60 mL/min/1.73 m2 in analyses unadjusted for multiplicity.




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Visit-to-Visit HbA1c Variability Is Associated With Cardiovascular Disease and Microvascular Complications in Patients With Newly Diagnosed Type 2 Diabetes

OBJECTIVE

To investigate the association between visit-to-visit HbA1c variability and cardiovascular events and microvascular complications in patients with newly diagnosed type 2 diabetes.

RESEARCH DESIGN AND METHODS

This retrospective cohort study analyzed patients from Tayside and Fife in the Scottish Care Information–Diabetes Collaboration (SCI-DC) who were observable from the diagnosis of diabetes and had at least five HbA1c measurements before the outcomes were evaluated. We used the previously reported HbA1c variability score (HVS), calculated as the percentage of the number of changes in HbA1c >0.5% (5.5 mmol/mol) among all HbA1c measurements within an individual. The association between HVS and 10 outcomes was assessed using Cox proportional hazards models.

RESULTS

We included 13,111–19,883 patients in the analyses of each outcome. The patients with HVS >60% were associated with elevated risks of all outcomes compared with the lowest quintile (for example, HVS >80 to ≤100 vs. HVS ≥0 to ≤20, hazard ratio 2.38 [95% CI 1.61–3.53] for major adverse cardiovascular events, 2.4 [1.72–3.33] for all-cause mortality, 2.4 [1.13–5.11] for atherosclerotic cardiovascular death, 2.63 [1.81–3.84] for coronary artery disease, 2.04 [1.12–3.73] for ischemic stroke, 3.23 [1.76–5.93] for heart failure, 7.4 [3.84–14.27] for diabetic retinopathy, 3.07 [2.23–4.22] for diabetic peripheral neuropathy, 5.24 [2.61–10.49] for diabetic foot ulcer, and 3.49 [2.47–4.95] for new-onset chronic kidney disease). Four sensitivity analyses, including adjustment for time-weighted average HbA1c, confirmed the robustness of the results.

CONCLUSIONS

Our study shows that higher HbA1c variability is associated with increased risks of all-cause mortality, cardiovascular events, and microvascular complications of diabetes independently of high HbA1c.




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Impact of Glucose Level on Micro- and Macrovascular Disease in the General Population: A Mendelian Randomization Study

OBJECTIVE

To evaluate whether high glucose levels in the normoglycemic range and higher have a causal genetic effect on risk of retinopathy, neuropathy, nephropathy, chronic kidney disease (CKD), peripheral arterial disease (PAD), and myocardial infarction (MI; positive control) in the general population.

RESEARCH DESIGN AND METHODS

This study applied observational and one-sample Mendelian randomization (MR) analyses to individual-level data from 117,193 Danish individuals, and validation by two-sample MR analyses on summary-level data from 133,010 individuals from the Meta-Analyses of Glucose and Insulin-Related Traits Consortium (MAGIC), 117,165 from the CKDGen Consortium, and 452,264 from the UK Biobank.

RESULTS

Observationally, glucose levels in the normoglycemic range and higher were associated with high risks of retinopathy, neuropathy, diabetic nephropathy, PAD, and MI (all P for trend <0.001). In genetic causal analyses, the risk ratio for a 1 mmol/L higher glucose level was 2.01 (95% CI 1.18–3.41) for retinopathy, 2.15 (1.38–3.35) for neuropathy, 1.58 (1.04–2.40) for diabetic nephropathy, 0.97 (0.84–1.12) for estimated glomerular filtration rate (eGFR) <60 mL/min/1.73 m2, 1.19 (0.90–1.58) for PAD, and 1.49 (1.02–2.17) for MI. Summary-level data from the MAGIC, the CKDGen Consortium, and the UK Biobank gave a genetic risk ratio of 4.55 (95% CI 2.26–9.15) for retinopathy, 1.48 (0.83–2.66) for peripheral neuropathy, 0.98 (0.94–1.01) for eGFR <60 mL/min/1.73 m2, and 1.23 (0.57–2.67) for PAD per 1 mmol/L higher glucose level.

CONCLUSIONS

Glucose levels in the normoglycemic range and higher were prospectively associated with a high risk of retinopathy, neuropathy, diabetic nephropathy, eGFR <60 mL/min/1.73 m2, PAD, and MI. These associations were confirmed in genetic causal analyses for retinopathy, neuropathy, diabetic nephropathy, and MI, but they could not be confirmed for PAD and seemed to be refuted for eGFR <60 mL/min/1.73 m2.




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A fresh look for your Microblogs, Twitter and Facebook Feeds

If you’ve browsed your Twitter or Facebook page feeds in the last week, you have probably noticed that we changed…




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Inoreader mobile apps updated to support Automatic Night Mode, Microblogs, Sort by Magic and popularity indicators.

Hey, it’s been quite some time without updates on this front, but our latest updates to our Android and iOS…




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Microvascular and Macrovascular Complications of Diabetes

Michael J. Fowler
Apr 1, 2008; 26:77-82
Diabetes Foundation




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How face surveillance threatens your privacy and freedom | Kade Crockford

Privacy isn't dead, but face surveillance technology might kill it, says civil rights advocate Kade Crockford. In an eye-opening talk, Kade outlines the startling reasons why this invasive technology -- powered by often-flawed facial recognition databases that track people without their knowledge -- poses unprecedented threats to your fundamental rights. Learn what can be done to ban government use before it's too late.




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Talking Across Divides And Quashing Conspiracy Theories: The Week’s Best Psychology Links

Our weekly round-up of the best psychology coverage from elsewhere on the web




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Tennessee School District Prohibits Crowdfunding for Class Supplies

A school district in Tennessee says it no longer wants teachers to use crowdfunding websites to get extra school supplies.




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Testing Encroaches on Arts Time, New Jersey Educators Report

Most New Jersey students get schooled in the arts, but time devoted to the subject has been dwindling.




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Crossroads / Steve Jacobs.




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Case update / presented by David Crocker, Edmund Barton Chambers.




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Forum 2019 : 4B Privacy law panel : recent developments and isues : slides / presented by Kelly Scott, Crown Solicitors Office.




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Forum 2019 : 5C Competition and consumer law in the digital age / slides presented by Thyme Burdon and Johanna Croser, Australian Competition and Consumer Commission.




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Forum 2019 : 7A Cross examination of documents / paper presented by: Edward Stratton-Smith, Edmund Barton Chambers.




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Implementation of the Digital Continuity 2020 Policy : across entities / The Auditor General.

"The objective of this audit was to examine the extent to which Australian Government entities have implemented the Digital Continuity 2020 policy, and how effectively the National Archives of Australia is monitoring, assisting, and encouraging entities to meet the specified targets of the policy."--Pages 7-8.




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Crossing the line : how Australian cricket lost its way / Gideon Haigh.

Cricket -- Australia -- Anecdotes.




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Rewording the brain : how cryptic crosswords can improve your memory and boost the power and agility of your brain / David Astle.

Memory.




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Race across the world : the incredible story of the world's greatest road race - the 1968 London to Sydney Marathon / John Smailes.

London-Sydney Marathon -- History.




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Defrosting ancient microbes : emerging genomes in a warmer world / Scott O. Rogers, Professor of Molecular Biology and Evolution, Department of Biological Sciences, Bowling Green State University ; John D. Castello, Professor Emeritus of Microbiology and

Microorganisms -- History.




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Sir Joseph Barcroft, family and friends.

[1924?]




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Young People Gather Across the Globe in Climate Strike

Young people across the globe marched, protested, and signaled calls to action today in the name of climate change. Here's what it looked like.




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Des maladies de l'encéphale et de la moelle épinière / par Jean Abercrombie, ouvrage traduit de l'anglais et augmenté de notes très nombreuses, par A.N. Gendrin.

A Paris : Germer-Bailliere ; A Londres : J.-B. Bailliere, 1835.




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Des microbes de l'oreille : bacteriologie, therapeutique / par A. Martha.

Paris : G. Steinheil, 1893.




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Diagnostica dei batteri delle acque con una guida alle ricerche batteriologiche e microscopiche / del Alessandro Lustig.

Torino : Rosenberg & Sellier, 1890.




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Die Behandlung der crouposen Lungenentzundung : nach den Grundsatzen des Professors von Jurgensen in Tubingen / von H. Wehberg.

Berlin : Heuser, 1889.




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Die multiple Fettgewebsnecrose : Klinische und experimentelle Studien / von Arthur Katz und Ferdinand Winkler ; mit einem Vorwort von Leopold Oser.

Berlin : S. Karger, 1899.




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Diphtheria and croup : what are they? / by Sir John Rose Cormack.

Edinburgh : Oliver and Boyd, 1876.




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Diseases in animals (tick fever) : progress report on teh reproductive forms of the micro-organism of tick fever, with some observations on the relationships and nomenclature of that disease (16th December, 1897) / by J. Sidney Hunt.

[Place of publication not identified] : [publisher not identified], [1897?]




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Diseases of the skin : their description, pathology, diagnosis, and treatment / by H. Radcliffe Crocker.

London : H.K. Lewis, 1903.




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Du croton-chlora ou chloral crotonique / par Ch. Livon.

Paris : Delahaye, 1877.




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The Edinburgh stereoscopic atlas of obstetrics / edited by G.F. Barbour Simpson and Edward Burnet ; with a preface by Sir J. Halliday Croom.

London : Caxton Pub. Co, 1908-1909.




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The effects of cross and self fertilisation in the vegetable kingdom / by Charles Darwin.

London : John Murray, 1876.




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Elémens d'histoire naturelle et de chimie / par M. Fourcroy.

Paris : chez Cuchet, 1791.




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Death, wearing a crown and accompanied by monsters, rides a white horse that tramples on men, women and children. Etching by J. Haynes, 1784, after J.H. Mortimer.

London (Norfolk Street, Strand) : J. Mortimer, Jany. 1st 1784.




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A ferry carrying people and game across a Scottish loch. Lithograph after Jacob Thompson, 18--.




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Banditti in Italy: a brigand leans against a rock by a river, as a woman stands in front of him to protect him from soldiers shooting at them across the river. Mezzotint by W. Say, 1824, after C.L. Eastake.

London (No. 90, Cheapside, & 8, Pall Mall) : Published ... by Hurst, Robinson & Co., March 1st. 1824.




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Banditti in Italy: a brigand leans against a rock by a river, as a woman stands in front of him to protect him from soldiers shooting at them across the river. Mezzotint by W. Say, 1824, after C.L. Eastake.

London (No. 90, Cheapside, & 8, Pall Mall) : Published ... by Hurst, Robinson & Co., March 1st. 1824.




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Banditti in Italy: a brigand leans against a rock by a river, as a woman stands in front of him to protect him from soldiers shooting at them across the river. Mezzotint by W. Say, 1824, after C.L. Eastake.

[London], [1824]




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The Scott Moncrieff system of sewage purification of by micro-organisms : reports, &c.

[Place of publication not identified] : [Publisher not identified], 1895.




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The wilderness of mind : sacred plants in cross-cultural perspective / Marlene Dobkin De Rios.

Beverly Hills : Sage Publications, 1976.




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Development of tolerance and cross-tolerance to psychomotor effects of benzodiazepines in man / by Kari Aranko.

Helsinki : Department of Pharmacology and Toxicology, University of Helsinki, 1985.




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Pam Liell papers relating to ‘Scrolls’ Book Club, 1994-2008 including correspondence with Alex Buzo, 1994-1998




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Asymptotic properties of the maximum likelihood and cross validation estimators for transformed Gaussian processes

François Bachoc, José Betancourt, Reinhard Furrer, Thierry Klein.

Source: Electronic Journal of Statistics, Volume 14, Number 1, 1962--2008.

Abstract:
The asymptotic analysis of covariance parameter estimation of Gaussian processes has been subject to intensive investigation. However, this asymptotic analysis is very scarce for non-Gaussian processes. In this paper, we study a class of non-Gaussian processes obtained by regular non-linear transformations of Gaussian processes. We provide the increasing-domain asymptotic properties of the (Gaussian) maximum likelihood and cross validation estimators of the covariance parameters of a non-Gaussian process of this class. We show that these estimators are consistent and asymptotically normal, although they are defined as if the process was Gaussian. They do not need to model or estimate the non-linear transformation. Our results can thus be interpreted as a robustness of (Gaussian) maximum likelihood and cross validation towards non-Gaussianity. Our proofs rely on two technical results that are of independent interest for the increasing-domain asymptotic literature of spatial processes. First, we show that, under mild assumptions, coefficients of inverses of large covariance matrices decay at an inverse polynomial rate as a function of the corresponding observation location distances. Second, we provide a general central limit theorem for quadratic forms obtained from transformed Gaussian processes. Finally, our asymptotic results are illustrated by numerical simulations.




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Differential network inference via the fused D-trace loss with cross variables

Yichong Wu, Tiejun Li, Xiaoping Liu, Luonan Chen.

Source: Electronic Journal of Statistics, Volume 14, Number 1, 1269--1301.

Abstract:
Detecting the change of biological interaction networks is of great importance in biological and medical research. We proposed a simple loss function, named as CrossFDTL, to identify the network change or differential network by estimating the difference between two precision matrices under Gaussian assumption. The CrossFDTL is a natural fusion of the D-trace loss for the considered two networks by imposing the $ell _{1}$ penalty to the differential matrix to ensure sparsity. The key point of our method is to utilize the cross variables, which correspond to the sum and difference of two precision matrices instead of using their original forms. Moreover, we developed an efficient minimization algorithm for the proposed loss function and further rigorously proved its convergence. Numerical results showed that our method outperforms the existing methods in both accuracy and convergence speed for the simulated and real data.




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Adaptive two-treatment three-period crossover design for normal responses

Uttam Bandyopadhyay, Shirsendu Mukherjee, Atanu Biswas.

Source: Brazilian Journal of Probability and Statistics, Volume 34, Number 2, 291--303.

Abstract:
In adaptive crossover design, our goal is to allocate more patients to a promising treatment sequence. The present work contains a very simple three period crossover design for two competing treatments where the allocation in period 3 is done on the basis of the data obtained from the first two periods. Assuming normality of response variables we use a reliability functional for the choice between two treatments. We calculate the allocation proportions and their standard errors corresponding to the possible treatment combinations. We also derive some asymptotic results and provide solutions on related inferential problems. Moreover, the proposed procedure is compared with a possible competitor. Finally, we use a data set to illustrate the applicability of the proposed design.