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An ionic-based carbon dot for enantioselective discrimination of nonaromatic amino alcohols

Analyst, 2020, 145,3395-3400
DOI: 10.1039/D0AN00399A, Paper
Datong Wu, Fei Pan, Li Gao, Yongxin Tao, Yong Kong
An ionic chiral carbon dot was designed and synthesized for the chiral recognition of nonaromatic amino alcohols.
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Why ammonium detection is particularly challenging but insightful with ionophore-based potentiometric sensors – an overview of the progress in the last 20 years

Analyst, 2020, 145,3188-3210
DOI: 10.1039/D0AN00327A, Critical Review
Open Access
María Cuartero, Noemi Colozza, Bibiana M. Fernández-Pérez, Gastón A. Crespo
An overview of ionophore-based electrodes for ammonium sensing critically analyzing contributions in the last 20 years and with focus in analytical applications.
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Paper-based platforms with coulometric readout for ascorbic acid determination in fruit juices

Analyst, 2020, 145,3431-3439
DOI: 10.1039/D0AN00477D, Paper
Estefanía Nunez-Bajo, M. Teresa Fernández-Abedul
Paper-based electrochemical platforms with coulometric readout are employed for fast and low cost determination of ascorbic acid in commercial juice samples.
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Recent developments of nanoenzyme-based colorimetric sensors for heavy metal detection and the interaction mechanism

Analyst, 2020, 145,3173-3187
DOI: 10.1039/D0AN00339E, Critical Review
Zhengquan Yan, Hua Yuan, Qi Zhao, Lin Xing, Xiaoyu Zheng, Weiguo Wang, Yulei Zhao, Yang Yu, Lei Hu, Wenli Yao
This work highlights the application and interaction mechanism of metal nanoparticles, metal oxides, metal sulfides, graphene-based nanomaterials and G-quadruplex, etc. in nanoenzyme-based colorimetric sensors.
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Novel ratiometric electrochemical sensor for no-wash detection of fluorene-9-bisphenol based on combining CoN nanoarrays with molecularly imprinted polymers

Analyst, 2020, 145,3320-3328
DOI: 10.1039/D0AN00345J, Paper
Zhaoyi Liu, Yong Zhang, Bing Li, Xiang Ren, Hongmin Ma, Qin Wei
A ratiometric molecularly imprinted polymers electrochemical sensor was fabricated based on the direct electrochemical oxidation of BHPF on CoN nanoarray electrode.
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Using the interfacial barrier effects of p–n junction on electrochemistry for detection of phosphate

Analyst, 2020, 145,3217-3221
DOI: 10.1039/C9AN02579K, Communication
Yu Ding, Minggang Zhao, Jiatuo Yu, Xiaomin Zhang, Zhengming Li, Hui Li
The electrochemical response to phosphate was produced by the induced change of the interfacial barrier of the NiO/ZnO p–n junction foam.
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Rapid detection of 21 β-lactams using an immunochromatographic assay based on the mutant BlaR-CTD protein from Bacillus Licheniformis

Analyst, 2020, 145,3257-3265
DOI: 10.1039/D0AN00421A, Paper
Yue Li, Xinxin Xu, Liqiang Liu, Hua Kuang, Liguang Xu, Chuanlai Xu
In this study, a gold immunochromatographic assay (GICA) based on a penicillin receptor protein (PBP) is proposed to simultaneously detect penicillin, cephalosporin, and carbapenem antibiotics in milk and chicken.
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Colorimetric identification of lanthanide ions based on two carboxylic acids as an artificial tongue

Analyst, 2020, 145,3359-3363
DOI: 10.1039/D0AN00357C, Paper
Chi Zhang, Juan Huang, Wei Wei, Zhengbo Chen
We report a colorimetric array, which consists of two carboxylic acids (quinolinic acid (QA), tannic acid (TCA)) as the sensor element and Eriochrome Black T (EBT) as the colorimetric signal readout.
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Removing interference-based effects from infrared spectra – interference fringes re-revisited

Analyst, 2020, 145,3385-3394
DOI: 10.1039/D0AN00062K, Paper
Thomas G. Mayerhöfer, Susanne Pahlow, Uwe Hübner, Jürgen Popp
Substantial refractive index mismatches between substrate and layers lead to undulating baselines and changes of band intensity, shape and position. For proper spectrum interpretation, all of these effects must be removed.
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Quantitative toxicological study of dose-dependent arsenic-induced cells via synchrotron-based STXM and FTIR measurement

Analyst, 2020, Accepted Manuscript
DOI: 10.1039/D0AN00346H, Paper
Huiqiang Liu, Junshan Xiu, Yunyan Liu, Bengyi Wang, Yanling Xue, Min Chen, Te Ji
Inorganic arsenic (iAs) is a well-known naturally occurring metalloid with abundant hazards in our environment, especially being a human carcinogen through arsenic contaminated drinking water. The iAs-related contamination is usually...
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A highly efficient preconcentration route for rapid and sensitive detection of endotoxin based on an electrochemical biosensor

Analyst, 2020, Accepted Manuscript
DOI: 10.1039/D0AN00315H, Paper
Wenrui Ma, Lulu Liu, Yi Xu, Li Wang, Li Chen, Sheng Yan, Lingling Shui, Zhijun Wang, Shunbo Li
An impedimetric aptasensor for detection of endotoxin in a microfluidic chip was proposed, in which the Apt/AuNPs/SPCE sensing surface was fabricated in screen-printed electrode with good biological activity and stability....
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FRET based fluorescent ratiometric probes for rapid detection of endogenous hydrogen sulphide in living cells

Analyst, 2020, Accepted Manuscript
DOI: 10.1039/D0AN00531B, Paper
Yuming Zhang, Yuncong Chen, Bai Yang, Xueling Xue, Weijiang He, Zijian Guo
Real time monitor of hydrogen sulphide (H2S) level change is of crucial importance for the study of its complicated roles in physiology. Herein, we developed a FRET strategy for designing...
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An electrochemical biosensor based on methylene blue-loaded nanocomposites as signal-amplifying tags to detect pathogenic bacteria

Analyst, 2020, Advance Article
DOI: 10.1039/D0AN00470G, Paper
Shengjun Bu, Kuiyu Wang, Zhongyi Li, Chengyu Wang, Zhuo Hao, Wensen Liu, Jiayu Wan
Synthesis of new methylene blue–magainin I organic–inorganic nanocomposites as electrochemical signal labels for the detection of bacteria.
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Liquid-crystal-based immunosensor for detection of cardiac troponin I

Analyst, 2020, Accepted Manuscript
DOI: 10.1039/D0AN00425A, Paper
Chunli Xia, dong Zhou, yueming Su, guangkai Zhou, Lishuang Yao, Weimin sun, yongjun Liu
Cardiac troponin I (cTnI) is one of the most sensitive and specific markers of myocardial cell injury, which can detect even minor myocardia damage. It is recognized as the main...
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A homogeneous photoelectrochemical hydrogen sulfide sensor based on the electronic transfer mediated by tetrasulfophthalocyanine

Analyst, 2020, Advance Article
DOI: 10.1039/D0AN00302F, Paper
Xinyang Wang, Huanan Zhao, Zhonghui Chen, Fang Luo, Longhua Guo, Bin Qiu, Zhenyu Lin, Jian Wang
A homogeneous photoelectrochemical sensor for H2S detection based on the electronic transfer mediated by [Fe(III)PcS4]+ was developed with an un-modified photoelectrode.
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A novel turn-on fluorescent sensor for sensitive detection of glutathione via gold nanoclusters preparation based on controllable ligand-induced etching

Analyst, 2020, Accepted Manuscript
DOI: 10.1039/D0AN00807A, Paper
Yun Chen, Xiawei Dong, Youkun Zheng, Yi-Han Wang, Zengchao Guo, Hui Jiang, Xuemei Wang
In this study, we report a facile one-pot chemical etching approach to simply and rapidly prepare gold nanoclusters capped with luminol (Lum-AuNCs) in alkaline aqueous solution at room temperature. A...
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Biocompatible Alkyne arms containing Schiff base Fluorescence Indicator for Duel detection of CdII and PbII at Physiological pH and its Application to Live Cell Imaging

Analyst, 2020, Accepted Manuscript
DOI: 10.1039/D0AN00862A, Paper
Jebastin Andrews S.G, Benita Jeba Silviya S, Jeyanthi Dharmaraj, Winfred Jebaraj J, Sathya Devi E, C. Balakrishnan
An alkyne arms containing salen-type Schiff base ligand, 6,6'-((1E,1'E)-(1,2-phenylenebis(azanylylidene))bis(ethan-1-yl-1-ylidene))bis(3-(prop-2-yn-1-yloxy)phenol) (H2L), is reported here as a dual chemosensor for CdII and PbII ions. The ligand, H2L was characterized by various spectral...
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A paper-supported sandwich immunosensor based on upconversion luminescence resonance energy transfer for the visual and quantitative determination of a cancer biomarker in human serum

Analyst, 2020, Accepted Manuscript
DOI: 10.1039/C9AN02307K, Paper
Mengyuan He, Ning Shang, Lin Shen, Zhi-hong Liu
In this paper, a paper-supported analytical device based on a sandwich immunoreaction and luminescence resonance energy transfer (LRET) was reported for the visual and quantitative determination of a cancer biomarker,...
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Acid–base titration using a microfluidic thread-based analytical device (μTAD)

Analyst, 2020, Advance Article
DOI: 10.1039/D0AN00522C, Paper
Purim Jarujamrus, Akarapong Prakobkij, Sodsai Puchum, Sawida Chaisamdaeng, Rattapol Meelapsom, Wipark Anutrasakda, Maliwan Amatatongchai, Sanoe Chairam, Daniel Citterio
This work presents a novel analytical approach for precise and quick (within 2 minutes) determination of acid and base concentrations (of very small amount) by titration using a microfluidic thread-based analytical device (μTAD).
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[ASAP] A Coculture Based Tyrosine-Tyrosinase Electrochemical Gene Circuit for Connecting Cellular Communication with Electronic Networks

ACS Synthetic Biology
DOI: 10.1021/acssynbio.9b00469




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[ASAP] Efficient and Reproducible Multigene Expression after Single-Step Transfection Using Improved BAC Transgenesis and Engineering Toolkit

ACS Synthetic Biology
DOI: 10.1021/acssynbio.9b00457




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[ASAP] Blue-Light-Switchable Bacterial Cell–Cell Adhesions Enable the Control of Multicellular Bacterial Communities

ACS Synthetic Biology
DOI: 10.1021/acssynbio.0c00054




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[ASAP] Genome-Wide CRISPRi-Based Identification of Targets for Decoupling Growth from Production

ACS Synthetic Biology
DOI: 10.1021/acssynbio.9b00143




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[ASAP] Introduction of the Menaquinone Biosynthetic Pathway into <italic toggle="yes">Rhodobacter sphaeroides</italic> and <italic toggle="yes">de Novo</italic> Synthesis of Menaquinone for Incorporation into He

ACS Synthetic Biology
DOI: 10.1021/acssynbio.0c00066




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[ASAP] A Synthetic Genetic Circuit Enables Precise Quantification of Direct Repeat Deletion in Bacteria

ACS Synthetic Biology
DOI: 10.1021/acssynbio.9b00256




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[ASAP] Facilitating Protein Expression with Portable 5'-UTR Secondary Structures in <italic toggle="yes">Bacillus licheniformis</italic>

ACS Synthetic Biology
DOI: 10.1021/acssynbio.9b00355




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[ASAP] MAPPS: A Web-Based Tool for Metabolic Pathway Prediction and Network Analysis in the Postgenomic Era

ACS Synthetic Biology
DOI: 10.1021/acssynbio.9b00397




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[ASAP] Transcript Barcoding Illuminates the Expression Level of Synthetic Constructs in <italic toggle="yes">E. coli</italic> Nissle Residing in the Mammalian Gut

ACS Synthetic Biology
DOI: 10.1021/acssynbio.0c00040




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[ASAP] Translation Related Factors Improve the Productivity of a <italic toggle="yes">Streptomyces</italic>-Based Cell-Free Protein Synthesis System

ACS Synthetic Biology
DOI: 10.1021/acssynbio.0c00140




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[ASAP] Bacteriophage Inspired Growth-Decoupled Recombinant Protein Production in <italic toggle="yes">Escherichia coli</italic>

ACS Synthetic Biology
DOI: 10.1021/acssynbio.0c00028




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[ASAP] Multicomponent Microscale Biosynthesis of Unnatural Cyanobacterial Indole Alkaloids

ACS Synthetic Biology
DOI: 10.1021/acssynbio.0c00038





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[ASAP] MymA Bioactivated Thioalkylbenzoxazole Prodrug Family Active against <italic toggle="yes">Mycobacterium tuberculosis</italic>

Journal of Medicinal Chemistry
DOI: 10.1021/acs.jmedchem.0c00003




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[ASAP] Molecule Property Analyses of Active Compounds for <italic toggle="yes">Mycobacterium tuberculosis</italic>

Journal of Medicinal Chemistry
DOI: 10.1021/acs.jmedchem.9b02075




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[ASAP] Structure-Based Bioisosterism Yields HIV-1 NNRTIs with Improved Drug-Resistance Profiles and Favorable Pharmacokinetic Properties

Journal of Medicinal Chemistry
DOI: 10.1021/acs.jmedchem.0c00117




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[ASAP] Molecular Interactions of Pyrazine-Based Compounds to Proteins

Journal of Medicinal Chemistry
DOI: 10.1021/acs.jmedchem.9b02021




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[ASAP] Treating Cancer by Spindle Assembly Checkpoint Abrogation: Discovery of Two Clinical Candidates, BAY 1161909 and BAY 1217389, Targeting MPS1 Kinase

Journal of Medicinal Chemistry
DOI: 10.1021/acs.jmedchem.9b02035




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[ASAP] Structure-Based Design of Highly Potent HIV-1 Protease Inhibitors Containing New Tricyclic Ring P2-Ligands: Design, Synthesis, Biological, and X-ray Structural Studies

Journal of Medicinal Chemistry
DOI: 10.1021/acs.jmedchem.0c00202




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[ASAP] Design and Characterization of the First Selective and Potent Mechanism-Based Inhibitor of Cytochrome P450 4Z1

Journal of Medicinal Chemistry
DOI: 10.1021/acs.jmedchem.0c00101




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[ASAP] Dual-Target Inhibitors Based on HDACs: Novel Antitumor Agents for Cancer Therapy

Journal of Medicinal Chemistry
DOI: 10.1021/acs.jmedchem.0c00491




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[ASAP] Design of Hydrazide-Bearing HDACIs Based on Panobinostat and Their p53 and FLT3-ITD Dependency in Antileukemia Activity

Journal of Medicinal Chemistry
DOI: 10.1021/acs.jmedchem.0c00442




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[ASAP] Exploration of the Structural Space in 4(3<italic toggle="yes">H</italic>)-Quinazolinone Antibacterials

Journal of Medicinal Chemistry
DOI: 10.1021/acs.jmedchem.0c00153




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[ASAP] Molecular Basis for Omapatrilat and Sampatrilat Binding to Neprilysin—Implications for Dual Inhibitor Design with Angiotensin-Converting Enzyme

Journal of Medicinal Chemistry
DOI: 10.1021/acs.jmedchem.0c00441




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[ASAP] Discovery of a Cyclic Choline Analog That Inhibits Anaerobic Choline Metabolism by Human Gut Bacteria

ACS Medicinal Chemistry Letters
DOI: 10.1021/acsmedchemlett.0c00005




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[ASAP] Glycans Meet Sphingolipids: Structure-Based Design of Glycan Containing Analogues of a Sphingosine Kinase Inhibitor

ACS Medicinal Chemistry Letters
DOI: 10.1021/acsmedchemlett.9b00665




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[ASAP] Peptoid NPhe<sup>4</sup> in AGRP-Based c[Pro<sup>1</sup>-Arg<sup>2</sup>-Phe<sup>3</sup>-Phe<sup>4</sup>-Xxx<sup>5</sup>-Ala<sup>6</sup>-Phe<sup>7</sup>

ACS Medicinal Chemistry Letters
DOI: 10.1021/acsmedchemlett.9b00641




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[ASAP] Pharmacophore-Based Virtual Screening for Identification of Negative Modulators of GLI1 as Potential Anticancer Agents

ACS Medicinal Chemistry Letters
DOI: 10.1021/acsmedchemlett.9b00639




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[ASAP] Novel Dithiolane-Based Ligands Combining Sigma and NMDA Receptor Interactions as Potential Neuroprotective Agents

ACS Medicinal Chemistry Letters
DOI: 10.1021/acsmedchemlett.0c00129




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[ASAP] Development of a Raltegravir-based Photoaffinity-Labeled Probe for Human Immunodeficiency Virus-1 Integrase Capture

ACS Medicinal Chemistry Letters
DOI: 10.1021/acsmedchemlett.0c00009




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[ASAP] Ligand Design for Cereblon Based Immunomodulatory Therapy

ACS Medicinal Chemistry Letters
DOI: 10.1021/acsmedchemlett.0c00214