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Osteopromotive carbon dots promote bone regeneration through the PERK-eIF2α-ATF4 pathway

Biomater. Sci., 2020, Advance Article
DOI: 10.1039/D0BM00424C, Paper
Nianqiang Jin, Nuo Jin, Zilin Wang, Lili Liu, Lin Meng, Daowei Li, Xing Li, Dabo Zhou, Jie Liu, Wenhuan Bu, Hongchen Sun, Bai Yang
Novel carbon dots induced ER stress and activated PERK-eIF2α-ATF4 pathway promote bone regeneration.
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Fixed-point “blasting” triggered by second near-infrared window light for augmented interventional photothermal therapy

Biomater. Sci., 2020, Advance Article
DOI: 10.1039/D0BM00372G, Paper
Yongbin Cao, Boshu Ouyang, Xiaowei Yang, Qin Jiang, Lin Yu, Shun Shen, Jiandong Ding, Wuli Yang
Tumors were effectively destroyed by a mild photothermal effect and the subsequent gas mechanical damage triggered by NIR-II light.
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Polydopamine-assisted one-step modification of nanofiber surfaces with adenosine to tune the osteogenic differentiation of mesenchymal stem cells and the maturation of osteoclasts

Biomater. Sci., 2020, Advance Article
DOI: 10.1039/C9BM01990A, Paper
Taufiq Ahmad, Hayeon Byun, Hyeok Jun Shin, Jinkyu Lee, Sajeesh Kumar Madhurakkat Perikamana, Eun Mi Kim, Young Min Shin, Heungsoo Shin
Adenosine and its receptors have emerged as alternative targets to control cellular functions for bone healing.
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Self-assembled nucleo-tripeptide hydrogels provide local and sustained doxorubicin release

Biomater. Sci., 2020, Advance Article
DOI: 10.1039/D0BM00134A, Paper
Kiheon Baek, Alexander David Noblett, Pengyu Ren, Laura J. Suggs
Doxorubicin is intercalated within the nanofibril structure of self-assembled nucleo-peptide hydrogels and injection leads to decrease in tumor volume and greater concentration of chemotherapeutic relative to soluble form.
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A conductive PEDOT/alginate porous scaffold as a platform to modulate the biological behaviors of brown adipose-derived stem cells

Biomater. Sci., 2020, Advance Article
DOI: 10.1039/C9BM02012H, Paper
Boguang Yang, Fanglian Yao, Lei Ye, Tong Hao, Yabin Zhang, Lei Zhang, Dianyu Dong, Wancai Fang, Yan Wang, Xiaoyang Zhang, Changyong Wang, Junjie Li
The development of three-dimensional conductive scaffolds is vital to support the adhesion, proliferation and myocardial differentiation of stem cells in cardiac tissue engineering.
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Trastuzumab targeted micellar delivery of docetaxel using dendron–polymer conjugates

Biomater. Sci., 2020, 8,2600-2610
DOI: 10.1039/C9BM01764J, Paper
Burcu Sumer Bolu, Bianka Golba, Amitav Sanyal, Rana Sanyal
Incorporation of a therapeutic antibody into nanosized drug delivery systems can improve their target specificity.
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Spatial immobilization of endogenous growth factors to control vascularization in bone tissue engineering

Biomater. Sci., 2020, 8,2577-2589
DOI: 10.1039/D0BM00087F, Paper
Marta R. Casanova, Catarina Oliveira, Emanuel M. Fernandes, Rui L. Reis, Tiago H. Silva, Albino Martins, Nuno M. Neves
An engineered biofunctional system comprises endogenous BMP-2 and VEGF bound in a parallel pattern. It successfully enabled obtaining the spatial osteogenic and angiogenic differentiation of human hBM-MSCs under basal culture conditions.
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A multifunctional metal-biopolymer coordinated double network hydrogel combined with multi-stimulus responsiveness, self-healing, shape memory and antibacterial properties

Biomater. Sci., 2020, Advance Article
DOI: 10.1039/D0BM00425A, Paper
Kun Yan, Feiyang Xu, Chunyu Wang, Yingying Li, Yuanli Chen, Xiufang Li, Zhentan Lu, Dong Wang
A universal, straightforward macroscale assembly technology has been presented for fabrication of polysaccharide-based multifunctional DN gels based on metal coordination chemistry.
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A transport system based on a quantum dot-modified nanotracer is genetically and developmentally stable in pregnant mice

Biomater. Sci., 2020, Advance Article
DOI: 10.1039/D0BM00311E, Paper
Open Access
Hye Jin Kim, Ji Sun Park, Se Won Yi, Minyeon Go, Hye-Ryun Kim, Su Jin Lee, Jong Min Park, Dong Hyun Cha, Sung Han Shim, Keun-Hong Park
The use of nanoscale materials (NMs) could cause problems such as cytotoxicity, genomic aberration, but the impacts of NM exposure during pregnancy remain uncharacterized in the context of clinical applications.
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Eco-friendly synthesis of glutathione-capped CdTe/CdSe/ZnSe core/double shell quantum dots: their cytotoxicity and genotoxicity effects on Chinese hamster ovary cells

Toxicol. Res., 2019, 8,868-874
DOI: 10.1039/C9TX00113A, Paper
Neo Mervyn Monaheng, Sundararajan Parani, Mary Gulumian, Oluwatobi Samuel Oluwafemi
In this work, we report green one-pot synthesis, cytotoxicity and genotoxicity of glutathione-capped CdTe/CdSe/ZnSe heterostructured quantum dots (QDs) using a label-free xCELLigence RTCA system as well as the Cytokinesis Blocked Micronucleus assay.
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Lipoic acid antagonizes paraquat-induced vascular endothelial dysfunction by suppressing mitochondrial reactive oxidative stress

Toxicol. Res., 2019, 8,918-927
DOI: 10.1039/C9TX00186G, Paper
Li Pang, Ping Deng, Yi-dan Liang, Jing-yu Qian, Li-Chuan Wu, Ling-ling Yang, Zheng-ping Yu, Zhou Zhou
α-Lipoic acid antagonizes paraquat toxicity.
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Thyroid endocrine status and biochemical stress responses in adult male Wistar rats chronically exposed to pristine polystyrene nanoplastics

Toxicol. Res., 2019, 8,953-963
DOI: 10.1039/C9TX00147F, Paper
Fatemeh Amereh, Akbar Eslami, Simin Fazelipour, Mohammad Rafiee, Mohammad Ismail Zibaii, Mohammad Babaei
At this time, little is known about the long-term effects of micro(nano)plastics on public health. In the present study, early warning signs of thyroid endocrine disruption were noticed in adult Wistar rats from the ingestion of virgin polystyrene nanoparticles.
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Reply to the ‘Comment on “Acetylcysteine in paracetamol poisoning: a perspective of 45 years of use”’ by M. E. Mullins, M. C. Yarema, M. L. A. Sivilotti, M. Thompson, D. A. Algren, M. C. Beuhler and C. P. Holstege, Toxicol. Res., 2019, 8, DOI: 10.1039/C9T

Toxicol. Res., 2019, 8,1059-1059
DOI: 10.1039/C9TX00216B, Comment
Open Access
D. Nicholas Bateman, James W. Dear
Mullins et al. made a comment on our article (DOI: 10.1039/C9TX00002J) stating they noticed the omission of the one-bag, standard concentration protocol which is shared by several centers in North America when we discussed IV acetylcysteine protocols.
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Biogenic Aspergillus tubingensis silver nanoparticles’ in vitro effects on human umbilical vein endothelial cells, normal human fibroblasts, HEPG2, and Galleria mellonella

Toxicol. Res., 2019, 8,789-801
DOI: 10.1039/C9TX00091G, Paper
Cristiane Angélica Ottoni, Durvanei Augusto Maria, Priscila Jane Romano de Oliveira Gonçalves, Welington Luiz de Araújo, Ana Olívia de Souza
Biogenic silver nanoparticles are ecofriendly and offers valuable possibilities of applications in several industrial areas.
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Cadmium telluride quantum dot-exposed human bronchial epithelial cells: a further study of the cellular response by proteomics

Toxicol. Res., 2019, 8,994-1001
DOI: 10.1039/C9TX00126C, Paper
Yan-Ming Xu, Heng Wee Tan, Wei Zheng, Zhan-Ling Liang, Fei-Yuan Yu, Dan-Dan Wu, Yue Yao, Qiu-Hua Zhong, Rui Yan, Andy T. Y. Lau
A comparative proteome analysis was conducted to identify global changes in the protein expression profiles of cadmium telluride quantum dot-exposed human bronchial epithelial BEAS-2B cells.
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Effects of moderate red wine on cardiovascular risk factors in diabetics: a systematic review and meta-analysis of randomized controlled trials

Toxicol. Res., 2019, 8,979-987
DOI: 10.1039/C9TX00227H, Paper
Saavia Alice Naame, Decheng Li, Ruixue Huang
Diabetes mellitus is of major public health concerns; its incidence is continuously increasing.
The content of this RSS Feed (c) The Royal Society of Chemistry




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The protective effect of thymoquinone on tert-butylhydroquinone induced cytotoxicity in human umbilical vein endothelial cells

Toxicol. Res., 2019, 8,1050-1056
DOI: 10.1039/C9TX00235A, Paper
Zahra Karimi, Maryam Ghaffari, Jafar Ezzati Nazhad Dolatabadi, Parvin Dehghan
2-tert-Butyl-4-hydroquinone (TBHQ) is used for inhibition of oxidative rancidity in the food industry.
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Only 13% of industrial units resume ops after Odisha eases lockdown

Micro units in the state have not been able to resume operations to catch up with their larger peers




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Lockdown period not to be counted for determining residency of NRIs: CBDT

There were apprehensions that this extended stay could lead to these individuals becoming Indian residents as per Section 6 of the Income Tax Act




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Covid-19 lockdown effect: Every second Indian now on internet in cities

The data released by Nielsen and the Broadcast Audience Research Council (BARC) shows that internet usage has grown sharply in cities over the last one month, touching 54 per cent




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Lockdown worsening poverty levels among workers in informal economy: ILO

In high-income countries, relative poverty levels among informal workers are estimated to increase by 52 percentage points




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Lockdown: Closure of commercial activity has hit Bihar, UP villages

But most respondents to a survey conducted by Smart Power India said they saw a positive change in social hygiene behaviour during lockdown




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Conductive-bridging random-access memories for emerging neuromorphic computing

Nanoscale, 2020, Advance Article
DOI: 10.1039/D0NR01671C, Review Article
Jun-Hwe Cha, Sang Yoon Yang, Jungyeop Oh, Shinhyun Choi, Sangsu Park, Byung Chul Jang, Wonbae Ahn, Sung-Yool Choi
This review covers CBRAM-based artificial synapses and neurons towards emerging computing applications from the operation principles of CBRAMs to state-of-the-art experimental demonstrations.
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Boosting the photocatalytic CO2 reduction of metal–organic frameworks by encapsulating carbon dots

Nanoscale, 2020, 12,9533-9540
DOI: 10.1039/D0NR01696A, Paper
Shumin Li, Kang Ji, Meng Zhang, Cangshuang He, Jin Wang, Zhengquan Li
Small carbon dots as cocatalysts were loaded in MOF particles for CO2 reduction and their location effect was explored.
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Interfacial synergy between dispersed Ru sub-nanoclusters and porous NiFe layered double hydroxide on accelerated overall water splitting by intermediate modulation

Nanoscale, 2020, 12,9669-9679
DOI: 10.1039/D0NR01491E, Paper
Yao Wang, Peng Zheng, Mingxuan Li, Yunrui Li, Xin Zhang, Juan Chen, Xu Fang, Yujie Liu, Xiaolin Yuan, Xiaoping Dai, Hai Wang
Benefitting from the desired potential-induced interfacial synergy, the Ru–NiFe LDH interfaces will convert to RuO2–NiFe(OOH)x interfaces to meet the requirements of an anode and cathode reaction, respectively.
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N- & S-co-doped carbon nanofiber network embedded with ultrafine NiCo nanoalloy for efficient oxygen electrocatalysis and Zn–air batteries

Nanoscale, 2020, 12,9581-9589
DOI: 10.1039/D0NR01516D, Paper
Chaojun Liu, Zhuang Wang, Xin Zong, Yingmin Jin, Dong Li, Yueping Xiong, Gang Wu
A 3D carbon nanofiber network embedded with ultrafine nanoparticles is prepared by electrospinning. Thioacetamide is used to prevent the aggregation of active sites.
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Enhanced type I photoreaction of indocyanine green via electrostatic-force-driven aggregation

Nanoscale, 2020, 12,9517-9523
DOI: 10.1039/D0NR01208D, Paper
Huizhen Fan, Yu Fan, Wenna Du, Rui Cai, Xinshuang Gao, Xinfeng Liu, Hao Wang, Lei Wang, Xiaochun Wu
ICG forms aggregates in positively charged mesoporous silica, which show an enhanced type I photoreaction pathway.
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Reply to the ‘Comment on “Hierarchically porous, ultra-strong reduced graphene oxide–cellulose nanocrystal sponges for exceptional adsorption of water contaminants”’ by J. Ma, Y. Xiong and F. Yu, Nanoscale, 2019, 11, DOI: 10.1039/C8NR08780F

Nanoscale, 2020, 12,9899-9901
DOI: 10.1039/D0NR01846E, Comment
Nariman Yousefi, Nathalie Tufenkji
We respond to the comments of Ma et al. and clarify the rationale behind our methodology and why it is suitable for our work.
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Binding patterns and dynamics of double-stranded DNA on the phosphorene surface

Nanoscale, 2020, 12,9430-9439
DOI: 10.1039/D0NR01403F, Paper
Baoyu Li, Xuejie Xie, Guangxin Duan, Serena H. Chen, Xuan-Yu Meng, Ruhong Zhou
Molecular dynamics simulations and electrophoresis experiments show that dsDNA can form a stable binding on the phosphorene surface through the terminal base pairs and adopt an upright orientation regardless of its initial configurations.
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NiSe2-anchored N, S-doped graphene/Ni foam as a free-standing bifunctional electrocatalyst for efficient water splitting

Nanoscale, 2020, 12,9866-9872
DOI: 10.1039/D0NR00879F, Paper
Jinhao Zhou, Zegao Wang, Dongxu Yang, Fei Qi, Xin Hao, Wanli Zhang, Yuanfu Chen
A strategy to synthesize free-standing electrocatalysts coupling active nanostructured NiSe2 with conductive S, N-doped 3D graphene foam (3DSNG) is presented and the hybrid delivers superior performances for the HER, OER and overall water splitting.
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Modulated podosome patterning in osteoclasts by fullerenol nanoparticles disturbs the bone resorption for osteoporosis treatment

Nanoscale, 2020, 12,9359-9365
DOI: 10.1039/D0NR01625J, Communication
Kui Chen, Huan Geng, Wei Liang, Haojun Liang, Yujiao Wang, Jianglong Kong, Jiaxin Zhang, Yuelan Liang, Ziteng Chen, Jiacheng Li, Ya-nan Chang, Juan Li, Gengyan Xing, Gengmei Xing
Fullerenol hampers podosome patterning in osteoclasts, results in the failure of bone resorption.
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Trace metals dramatically boost oxygen electrocatalysis of N-doped coal-derived carbon for zinc–air batteries

Nanoscale, 2020, 12,9628-9639
DOI: 10.1039/C9NR10800A, Paper
Huimin Liu, Xinning Huang, Zhenjie Lu, Tao Wang, Yaming Zhu, Junxia Cheng, Yue Wang, Dongling Wu, Zhenyu Sun, Alex W. Robertson, Xingxing Chen
The commercialization of metal–air batteries requires efficient, low-cost, and stable bifunctional electrocatalysts for reversible electrocatalysis of the oxygen reduction reaction (ORR) and the oxygen evolution reaction (OER).
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Clear observation of the formation of nanoparticles inside the ablation bubble through a laser-induced flat transparent window by laser scattering

Nanoscale, 2020, 12,9640-9646
DOI: 10.1039/C9NR10560C, Paper
Kota Ando, Takashi Nakajima
We demonstrate the clear observation of laser-scattering signals from Ag nanoparticles (NPs) inside an ablation bubble.
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Tuning the electronic structure of transition metals embedded in nitrogen-doped graphene for electrocatalytic nitrogen reduction: a first-principles study

Nanoscale, 2020, 12,9696-9707
DOI: 10.1039/D0NR00072H, Paper
Xiaonan Zheng, Yuan Yao, Ya Wang, Yang Liu
The Fe/Mn–N–C catalyst is a promising candidate for the NRR as it shows significantly improved NRR catalytic activity and strong selectivity against the HER.
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Double Fano resonances in hybrid disk/rod artificial plasmonic molecules based on dipole-quadrupole coupling

Nanoscale, 2020, 12,9776-9785
DOI: 10.1039/D0NR00461H, Paper
Zhiquan Chen, Shi Zhang, Yiqin Chen, Yanjun Liu, Ping Li, Zhaolong Wang, Xupeng Zhu, Kaixi Bi, Huigao Duan
Double Fano resonances can be aroused in a simple disk and rods coupled artificial plasmonic molecule. Two Fano peaks can be independently tuned by changing one rod length or the gap distances between rods and disk.
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Whispering gallery mode emission from dye-doped polymer fiber cross-sections fabricated by near-field electrospinning

Nanoscale, 2020, 12,9873-9883
DOI: 10.1039/D0NR00147C, Paper
Joseph E. Cheeney, Stephen T. Hsieh, Nosang V. Myung, Elaine D. Haberer
Near-field electrospun polymer microfibers were utilized to support whispering gallery mode resonances. The fibers were utilized for water–ethanol sensing.
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Formation and manipulation of domain walls with 2-nm domain periodicity in BaTiO3 without contact electrodes

Nanoscale, 2020, Accepted Manuscript
DOI: 10.1039/D0NR01747G, Paper
Maya Barzilay, Yachin Ivry
Interfaces at the two-dimensional limit in oxide materials exhibit a rich span of functionality that differs significantly from the bulk behavior. Among such interfaces, domain walls in ferroelectrics draw special...
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Direct carbonization of organic solvent toward graphene quantum dots

Nanoscale, 2020, Accepted Manuscript
DOI: 10.1039/D0NR01903H, Communication
Hongji Liu, Xiaotong Lv, Changwei Li, Yong Qian, Xingyu Wang, Lin Hu, Yu-Cai Wang, Wenchu Lin, Hui Wang
The bottom-up synthesis of graphene quantum dots (GQDs) using solvothermal method has attracted considerable attention because of their fewer defects and controllable size/ morphology. However, the influence of organic solvent...
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Black in America: The Paradox of the Color Line


 
At the start of the twentieth century, the pre-eminent black sociologist, W.E.B. DuBois, identified the color line as America's great problem. While the color line is increasingly variegated beyond black and white, and more openly discussed than ever before as more racial and ethnic groups call America home, his words still ring true.
 
Today, post-racial and colorblind ideals dominate the American narrative, obscuring the reality of racism and discrimination

Read More...




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Black in America: The Paradox of the Color Line


 
At the start of the twentieth century, the pre-eminent black sociologist, W.E.B. DuBois, identified the color line as America's great problem. While the color line is increasingly variegated beyond black and white, and more openly discussed than ever before as more racial and ethnic groups call America home, his words still ring true.
 
Today, post-racial and colorblind ideals dominate the American narrative, obscuring the reality of racism and discrimination

Read More...




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How to find a postdoc position that’s right for you

Our Letters to Young Scientists columnists share insights into the postdoc application process




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Suffering from COVID-19 anxiety? Here’s what you can do

A postdoc shares what she learned by talking to a friend who is a psychiatrist




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'Damn those Confederate torpedoes" - Farragut




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"Way down upon de Swanee Ribber"




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Eglin neighbors remember Doolittle Raiders




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The Waltons were freedom-fighters




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San-ai-an, "the adobe of three loves"




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Dorr house was post-bellum social center




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Pioneer doctor gained fame as botanist




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The city hall that doesn't look like one