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Sofosbuvir and Ribavirin for Hepatitis C Genotype 1 in Patients With Unfavorable Treatment Characteristics: A Randomized Clinical Trial

Interview with Anthony S. Fauci, MD, author of Sofosbuvir and Ribavirin for Hepatitis C Genotype 1 in Patients With Unfavorable Treatment Characteristics: A Randomized Clinical Trial




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Mobility Limitation in the Older Patient: A Clinical Review

Interview with Cynthia J. Brown, MD, author of Mobility Limitation in the Older Patient: A Clinical Review




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Repeat Bone Mineral Density Screening and Prediction of Hip and Major Osteoporotic Fracture

Interview with Sarah D. Berry, MD, author of Repeat Bone Mineral Density Screening and Prediction of Hip and Major Osteoporotic Fracture




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Evaluation of Surveillance Bias and the Validity of the Venous Thromboembolism Quality Measure

Interview with Karl Y. Bilimoria, MD, author of Evaluation of Surveillance Bias and the Validity of the Venous Thromboembolism Quality Measure




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Association of Testosterone Therapy With Mortality, Myocardial Infarction, and Stroke in Men With Low Testosterone Levels

Interview with Michael Ho, MD, PhD, author of Association of Testosterone Therapy With Mortality, Myocardial Infarction, and Stroke in Men With Low Testosterone Levels




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JEffect of Weight Reduction and Cardiometabolic Risk Factor Management on Symptom Burden and Severity in Patients With Atrial Fibrillation: A Randomized Clinical Trial

Interview with Prashanthan Sanders, MBBS, PhD, author of Effect of Weight Reduction and Cardiometabolic Risk Factor Management on Symptom Burden and Severity in Patients With Atrial Fibrillation: A Randomized Clinical Trial




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Effect of Communication Skills Training for Residents and Nurse Practitioners on Quality of Communication With Patients With Serious Illness: A Randomized Trial

Interview with J. Randall Curtis, MD, MPH, author of Effect of Communication Skills Training for Residents and Nurse Practitioners on Quality of Communication With Patients With Serious Illness: A Randomized Trial




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Weight Change and Health Outcomes at 3 Years After Bariatric Surgery Among Individuals With Severe Obesity

Interview with Anita P. Courcoulas, MD, MPH, author of Weight Change and Health Outcomes at 3 Years After Bariatric Surgery Among Individuals With Severe Obesity




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Cognitive Behavioral Therapy Plus Amitriptyline for Chronic Migraine in Children and Adolescents

Interview with Scott W. Powers, PhD, author of Cognitive Behavioral Therapy Plus Amitriptyline for Chronic Migraine in Children and Adolescents




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Long-term Drug Treatment for Obesity: A Systematic and Clinical Review

Interview with Susan Z. Yanovski, MD, author of Long-term Drug Treatment for Obesity: A Systematic and Clinical Review




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Calcium Density of Coronary Artery Plaque and Risk of Incident Cardiovascular Events

Interview with Michael H. Criqui, MD, MPH, author of Calcium Density of Coronary Artery Plaque and Risk of Incident Cardiovascular Events




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Association Between Participation in a Multipayer Medical Home Intervention and Changes in Quality, Utilization, and Costs of Care

Interview with Mark W. Friedberg, MD, MPP, author of Association Between Participation in a Multipayer Medical Home Intervention and Changes in Quality, Utilization, and Costs of Care




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Associations of Housing Mobility Interventions for Children in High-Poverty Neighborhoods With Subsequent Mental Disorders During Adolescence

Interview with Ronald C. Kessler, PhD, author of Associations of Housing Mobility Interventions for Children in High-Poverty Neighborhoods With Subsequent Mental Disorders During Adolescence




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Web-Based Alcohol Screening and Brief Intervention for University Students: A Randomized Trial

Interview with Nicholas J. Horton, ScD, author of Web-Based Alcohol Screening and Brief Intervention for University Students: A Randomized Trial




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Door-to-Needle Times for Tissue Plasminogen Activator Administration and Clinical Outcomes in Acute Ischemic Stroke Before and After a Quality Improvement Initiative

Interview with Gregg C. Fonarow, MD, author of Door-to-Needle Times for Tissue Plasminogen Activator Administration and Clinical Outcomes in Acute Ischemic Stroke Before and After a Quality Improvement Initiative




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Prevalence of Type 1 and Type 2 Diabetes Among Children and Adolescents From 2001 to 2009

Interview with Dana Dabelea, MD, PhD, author of Prevalence of Type 1 and Type 2 Diabetes Among Children and Adolescents From 2001 to 2009




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Effect of Structured Physical Activity on Prevention of Major Mobility Disability in Older Adults: The LIFE Study Randomized Clinical Trial

Interview with Marco Pahor, MD, author of Effect of Structured Physical Activity on Prevention of Major Mobility Disability in Older Adults: The LIFE Study Randomized Clinical Trial




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Association of Azithromycin With Mortality and Cardiovascular Events Among Older Patients Hospitalized With Pneumoniaew

Interview with Eric M. Mortensen, MD, MSc, author of Association of Azithromycin With Mortality and Cardiovascular Events Among Older Patients Hospitalized With Pneumonia




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Association Between Intensification of Metformin Treatment With Insulin vs Sulfonylureas and Cardiovascular Events and All-Cause Mortality Among Patients With Diabetes

Interview with Christianne L. Roumie, MD, MPH, author of Association Between Intensification of Metformin Treatment With Insulin vs Sulfonylureas and Cardiovascular Events and All-Cause Mortality Among Patients With Diabetes




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Nonmyeloablative HLA-Matched Sibling Allogeneic Hematopoietic Stem Cell Transplantation for Severe Sickle Cell Phenotype

Interview with John F. Tisdale, MD, author of Nonmyeloablative HLA-Matched Sibling Allogeneic Hematopoietic Stem Cell Transplantation for Severe Sickle Cell Phenotype




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Time Elapsed After Ischemic Stroke and Risk of Adverse Cardiovascular Events and Mortality Following Elective Noncardiac Surgery

Interview with Mads E. Jørgensen, MB, author of Time Elapsed After Ischemic Stroke and Risk of Adverse Cardiovascular Events and Mortality Following Elective Noncardiac Surgery




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Use of and Mortality After Bilateral Mastectomy Compared With Other Surgical Treatments for Breast Cancer in California, 1998-2011

Interview with Allison W. Kurian, MD, MSc, author of Use of and Mortality After Bilateral Mastectomy Compared With Other Surgical Treatments for Breast Cancer in California, 1998-2011




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Clinical and Safety Outcomes Associated With Treatment of Acute Venous Thromboembolism: A Systematic Review and Meta-analysis

Interview with Marc Carrier, MD, MSc, author of Clinical and Safety Outcomes Associated With Treatment of Acute Venous Thromboembolism: A Systematic Review and Meta-analysis




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Obstetric Quality Indicators and Morbidity

Interview with Elizabeth A Howell, MD, MPP, author of Durability of Benefits of an Outpatient Antimicrobial Stewardship Intervention After Discontinuation of Audit and Feedback




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Medical Liability and Reform

Interview with Michelle M. Mello, JD, PhD, MPhil, author of The Medical Liability Climate and Prospects for Reform




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Resident Duty Hour Reforms and Patient Outcomes

Interview with Mitesh S. Patel, MD, MBA, MS, author of Association of the 2011 ACGME Resident Duty Hour Reforms With Mortality and Readmissions Among Hospitalized Medicare Patients




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Glycemic Index, Cardiovascular Disease, and Insulin Sensitivity

Interview with Frank M. Sacks, MD, author of Effects of High vs Low Glycemic Index of Dietary Carbohydrate on Cardiovascular Disease Risk Factors and Insulin Sensitivity




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Treatment of Diabetes and Long-term Mortality

Interview with David M. Nathan, MD, author of Association Between 7 Years of Intensive Treatment of Type 1 Diabetes and Long-term Mortality




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Corticosteroids for Severe Community-Acquired Pneumonia

Interview with Antoni Torres, MD, PhD, author of Effect of Corticosteroids on Treatment Failure Among Hospitalized Patients With Severe Community-Acquired Pneumonia and High Inflammatory Response: A Randomized Clinical Trial




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Housing Stability Among Homeless Adults With Mental Illness

Interview with Vicky Stergiopoulos, MD, author of Effect of Scattered-Site Housing Using Rent Supplements and Intensive Case Management on Housing Stability Among Homeless Adults With Mental Illness




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The ADA, Disability, and Identity

Interview with Eve Hill, JD, author of The ADA, Disability, and Identity




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Mortality, Hospitalizations, and Expenditures for the Medicare Population

Interview with Harlan M. Krumholz, MD, SM, author of Mortality, Hospitalizations, and Expenditures for the Medicare Population Aged 65 Years or Older, 1999-2013






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Explaining the Improved Health of the US: Mortality Trends 1969-2013

Interview with Ahmedin Jemal, DVM, PhD, author of Temporal Trends in Mortality in the United States, 1969-2013, and J. Michael McGinnis, MD, MPP, author of Mortality Trends and Signs of Health Progress. Also in this episode is a conversation with Christopher J.L. Murray, MD, DPhil, a Professor of Global Health at the University of Washington and Institute Director of the Institute for Health Metrics and Evaluation.





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Metformin for Adolescents With Type 1 Diabetes

Interview with Ingrid M. Libman, MD, PhD, author of Effect of Metformin Added to Insulin on Glycemic Control Among Overweight/Obese Adolescents With Type 1 Diabetes




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Antibiotic Therapy for Community-Acquired Pneumonia in Adults

Community acquired pneumonia accounts for 600,000 hospital admissions a year. Many patients with this disease are quite ill and have a very high mortality. To save lives, the appropriate antibiotics should be given in a timely basis, but it is not clear what the best antibiotics are and how long they should be given. In this podcast we interview the author of a JAMA review on community acquired pneumonia, Dr Jonathan Lee, author of Antibiotic Therapy for Adults Hospitalized With Community-Acquired Pneumonia, who performed a systematic review of the literature to determine the best way to treat community acquired pneumonia.








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Value-Driven Outcomes Program and Health Care Cost and Quality

Interview with Vivian S. Lee, MD, PhD, MBA;, author of Implementation of a Value-Driven Outcomes Program to Identify High Variability in Clinical Costs and Outcomes: Association With Reduced Cost and Improved Quality, and Michael E. Porter, PhD, author of From Volume to Value in Health Care: The Work Begins




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What Should Students or Residents Do When Abused by Faculty

Approximately one-third of all medical school graduates report having been abused as students. Medical student and resident abuse has long been considered unacceptable behavior but still persists in the teaching environment. In this podcast we discuss how students and residents might respond to these events. We interview Geoffrey Young, MD, from the Association of American Medical Colleges and Thomas J. Nasca, MD, from the Accreditation Council for Graduate Medical Education, who discuss how they expect medical schools to respond to abusive behaviors and what resources are available to students and residents who have been abused to report those experiences without fearing retribution.

Article discussed in this episode:

Medical Student Mistreatment

 









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USPSTF Recommendation: Calcium and Vitamin D to Prevent Fractures and Interventions to Prevent Falls in Community-Dwelling Adults

Interview with Alex H Krist, MD, MPH, Task Force member and co-author of Vitamin D, Calcium, or Combined Supplementation for the Primary Prevention of Fractures in Community-Dwelling Adults: US Preventive Services Task Force Recommendation Statement, and Interventions to Prevent Falls in Community-Dwelling Older Adults: US Preventive Services Task Force Recommendation Statement