Chronic obstructive pulmonary disease (COPD) is characterised by persistent respiratory symptoms and airflow limitation, which is caused by small airway disease (bronchiolitis) and alveolar destruction (emphysema) [1]. Patients primarily suffering from severe emphysema are often limited in exercise capacity due to the consequences of hyperinflation [2].

It is a source of frustration to many clinicians: you know what the patient's problem is, you know that effective and safe treatment is available, you've explained the disease and its causative mechanisms, the treatment and its principles, and the importance of taking the controller medication daily, you've prescribed this highly effective therapy and you've approached the patient with respect and patience, yet somehow the patient does not take the medication. When this patient has another exacerbation, you know it could have been prevented by following your advice and taking the medication.

Sleep and breathing disorders are highly prevalent, representing a growing subspecialty of respiratory medicine. The term sleep disordered breathing (SDB) encompasses a range of conditions characterised by abnormal breathing during sleep, from chronic or habitual snoring, to frank obstructive sleep apnoea (OSA) or, in some cases, central sleep apnoea (CSA) and hypoventilation syndromes. OSA is the commonest form of SDB, leading to many potential consequences and adverse clinical outcomes, including excessive daytime sleepiness, impaired daytime function, metabolic dysfunction, and an increased risk of cardiovascular disease and mortality [1]. The estimated reported prevalence of moderate-to-severe SDB (≥15 events·h^–1) was 23.4% in women and 49.7% in men, and the prevalence of symptomatic OSA was 9% and 13%, respectively [2]. However, in some populations, the prevalence of OSA is substantially higher, such as in patients been evaluated for bariatric surgery (estimated range 70–80%), in patients who have had a transient ischaemic attack or stroke (estimated range 60–70%) and in patients with cardiometabolic disease [3–6]. Limited data have been reported on CSA and non-obstructive sleep-related hypoventilation, which have received considerable interest in the sleep field within the past 10 years. Even if their prevalence was noted to be quite low relative to the prevalence of OSA [7], they are quite common in specific subpopulations [8–10].

In 2016, the proportion of Neisseria gonorrhoeae isolates with reduced susceptibility to azithromycin rose to 3.6%. A phylogenetic analysis of 334 N. gonorrhoeae isolates collected in 2016 revealed a single, geographically diverse lineage of isolates with MICs of 2 to 16 μg/ml that carried a mosaic-like mtr locus, whereas the majority of isolates with MICs of ≥16 μg/ml appeared sporadically and carried 23S rRNA mutations. Continued molecular surveillance of N. gonorrhoeae isolates will identify new resistance mechanisms.

A cluster of dendritic cells (termed mregDCs), observed in humans and mice, restricted antitumor immunity.

Structured diabetes education (SDE) is an evidence-based intervention that supports self-management in people with type 2 diabetes. In the United Kingdom, health care providers working in primary care settings are responsible for referring people with type 2 diabetes to SDE programs. However, national audits record a high percentage of nonattenders. We explored the personal experience of living with type 2 diabetes that led to individuals declining invitations to attend SDE programs. The themes suggested that emotional, cognitive, and social issues related to diagnosis and living with diabetes may be responsible for declining to attend SDE and that these factors may be masked by explanations of practical barriers. A person-centered approach to understanding the personal meaning of being diagnosed and living with type 2 diabetes may help to identify individuals’ psychosocial barriers to attending SDE.

Background:

New technologies are being developed for early detection of multiple types of cancer simultaneously. To quantify the potential benefit, we estimated reductions in absolute cancer–related deaths that could occur if cancers diagnosed after metastasis (stage IV) were instead diagnosed at earlier stages.

The Law on Housing of Vietnam allows foreigners to purchase Vietnam property but with strict conditions and procedures as listed in the following infographic.

WELCOME TO EPISODE 37 OF THE TALENTED LEARNING SHOW! Learn how trade associations and training companies are now pivoting to total digital education due to […]

The post Podcast 37: How to Pivot to Digital Education – With Ashish Rangnekar appeared first on e-Learning Feeds.

उत्तर प्रदेश के सरकारी राज्य विश्वविद्यालय, निजी विश्वविद्यालयों एवं महाविद्यालयों के लाखों छात्र-छात्राओं के लिए अच्छी खबर है। अब वे घर बैठे प्रदेश भर के विषय विशेषज्ञों का लाभ ले सकेंगे। शासन ने इसके लिए एक केंद्रीयकृत पोर्टल बनाने...

The 36th edition of the European Athletics Indoor Championships is scheduled to take place from March 5 to 7 next year in Torun, Poland.

Which NFL teams have the easiest schedules in 2020?

Which NFL teams have the most difficult 2020 schedules?

The newly launched #SmithsonianEdu campaign highlights 1.7 million online tools geared specifically toward students and teachers

Educational status appears to have positive influence on a healthy diet, particularly in low income countries, according to new research examining European nutritional data.

Follow our live coronavirus updates here Coronavirus: the symptoms

Follow our live coronavirus updates here

A drug used to treat Ebola patients has shown "very promising" early results in a trial of people admitted to hospital with coronavirus.

British Airways is set to make up to 12,000 workers redundant, its parent company has said.

More than 1,000 British Airways pilots are set to lose their jobs as part of major redundancy plans announced by the airline, it is reported.

Fewer people would have died from coronavirus in the UK if the country had greater testing capacity sooner, Transport Secretary Grant Shapps has said.

Headteachers are planning for life after the lockdown to ensure the return to school will be safe for all children and staff.

The rate of transmission of coronavirus is "much reduced" and the death toll is steadily falling, the Downing Street press conference has heard.

Celebrations kick off tomorrow morning!

Smart Education And Learning Market Size, Share & Trends Analysis Report By Age, By Component (Hardware, Software, Service), By Learning Mode, By End User, By Region, And Segment Forecasts, 2020 - 2027Read the full report: https://www.reportlinker.com/p05891723/?utm_source=PRN The global smart education and learning market size is expected to reach USD 680.1 billion by 2027. The market is anticipated to witness a CAGR of 17.9% from 2020 to 2027. Demand for smart education and learning solutions is increasing among the growing population in corporate and academic sectors, owing to benefits such as improved education quality and easy access to educational content. Increasing adoption of consumer electronics, such as smartphones, e-readers, laptops, and e-learning applications, has altered conventional education methodology and has enhanced the efficiency of an individual to learn. Additionally, there are enormous opportunities for advancements in the market, owing to improved internet accessibility.Also, the COVID - 19 outbreak has emerged an opportunity for the market with an increasing number of states and countries closing educational institutes. For instance, over 90.0% of the world's students are not attending their schools due to this pandemic, as mentioned by UNESCO (The United Nations Educational, Scientific, and Cultural Organization). Commonwealth of Learning (COL), an intergovernmental organization of The Commonwealth (Canada), has supported educational institutions and governments in building robust distance education solutions for quality e-learning practices. However, lack of awareness among end-users about the latest technologies and inadequate amount of resources for delivering quality education in developing regions is anticipated to hinder market growth.The simulation-based learning segment is anticipated to exhibit the highest CAGR because this mode enables corporate professional and educational institutions to create a realistic experience in a controlled environment.It also allows professionals and learners to practice, navigate, explore, and obtain more information through a virtual medium before they start working on real-life tasks.Growing awareness among people and the rising popularity of smart education are encouraging solution providers to invest in research and development for creating more reliable, better, and cost-effective solutions. Manufacturers are making substantial investments in developing new products for enhancing the user experience.Smart education and learning market report highlights:• Growing demand for smart educational practices can be accredited to factors, such as reducing expenses of online training, curbing geographic challenges in physically attending classes, and time constraints faced by aspirants• Increasing penetration of the Internet of Things (IoT), enhanced internet accessibility, and rapid adoption of mobile technology have encouraged users to adopt smart education and learning solutions• Innovative techniques, such as gamification, Massive Open Online Courses (MOOCs), microlearning, and adaptive learning, which improve the overall educational process, are expected to drive the market over the projected period• North America accounted for the largest market share in 2019 owing to its large consumer base for e-learning methodsRead the full report: https://www.reportlinker.com/p05891723/?utm_source=PRN About Reportlinker ReportLinker is an award-winning market research solution. Reportlinker finds and organizes the latest industry data so you get all the market research you need - instantly, in one place. __________________________ Contact Clare: clare@reportlinker.com US: (339)-368-6001 Intl: +1 339-368-6001

Prabhudas Lilladher has a ‘reduce’ rating on Infosys Technologies as it feels that the outlook for the company and the software industry is quite weak in the near-term.

The full regular-season schedule is out. The Chiefs open defense of their Super Bowl title vs. Houston.

Which games should you circle on your calendar? Which rookie debut will be the most interesting?

France's minister of education, Jean-Michel Blanquer, talked with NPR about the gradual reopening of schools, which will be voluntary. Still, many parents and administrators are against the plan.

In the apocalyptic drama series, Reedus plays the popular character Daryl Dixon

• NFL releases 2020 schedule despite coronavirus concerns
• Chiefs host Texans on 10 September in annual kickoff game
• Brady to make Buccaneers debut on 13 September at Saints

The Kansas City Chiefs will open defense of their Super Bowl championship by hosting Houston on 10 September in the NFL’s annual kickoff game – pending developments in the coronavirus pandemic, of course.

The Texans won a regular-season game at Arrowhead Stadium in 2019, then blew a 24-0 lead in the divisional round of the playoffs.

Related: Ravens' Earl Thomas held at gunpoint by wife over alleged affair, police say

.@nflcommish on the release of the 2020 schedule pic.twitter.com/Mch0lgXkf8

It's the BBC's 'biggest push on education in its history' and kicks off Monday, April 20

The number of high intensity "heavy breathing" work-out machines such as treadmills and cross trainers will be hugely reduced in gyms to help make them safe when the lockdown ends.

Netflix is cutting down traffic to ease internet capacity as more people work from home. Here’s what it means for Australians’ streaming experience

• Follow the latest Australia coronavirus blog for live news and updates
• See all our coronavirus coverage

Netflix has agreed to reduce the data it uses to stream movies and TV shows across Australia as more and more people are working from home due to the coronavirus shutdown. But what will it mean for your viewing habits while you’re staying at home?

Related: Australian government asks Netflix and Stan to reduce data to avoid broadband overload

Related: As cinemas go dark, the film industry may go straight to Netflix

Sticking to social isolation just became easier. Keeping the kids occupied and their creativity flowing during coronavirus lockdown has just …

Continue reading "‘Draw a Stickman: Epic 3’ is Here to Provide Your Lockdown Edutainment"

Today marks Music Monday, an annual event in which thousands of Canadians come together in song and in support of music education. Hosted by the Coalition for Music Education, Music Monday unites musicians in communities from coast to coast to make a powerful statement about the importance of equitable access to quality music education for […]

The post Music Monday @ Home shines a spotlight on the importance of equitable access to music education appeared first on Music Canada.

The 24-year-old actress has been dating Scrubs star Zach Braff since April 2019.

With the Easter weekend approaching and lockdown in full swing, fans of all sports are scratching their heads wondering just what there will be to do.

While global sport remains at a standstill due to the coronavirus pandemic, 20 players from some of European football's biggest clubs will substitute their boots for controllers as they compete in the EA Sports's Fifa 20 Stay and Play Cup.

Tottenham are in talks with their former manager Mauricio Pochettino over reduction in his £8.5million-a-year salary, five months after he was sacked.

Damien Comolli, the former Liverpool and Tottenham director of football, believes the transfer window will be very different next time around due to the coronavirus pandemic.

Former Southampton and Everton boss and current Netherlands coach Ronald Koeman has been admitted to hospital in Amsterdam with heart problems.

Jose Mourinho is expecting to be limited to free agents and swap deals in the next transfer window, as the top-flight prepares for a drastically changed financial outlook brought on by the coronavirus pandemic.

Premier League clubs are working towards a restart as the whole sport battles with the coronavirus pandemic.

Chelsea and Australia striker Sam Kerr believes the coronavirus pandemic has put paid to any plans her national team-mates have to get pregnant in the next five years.

Macclesfield Town have been hit with an immediate seven-point deduction for failing to fulfil a fixture along with non-payment of their players.

Netherlands manager Ronald Koeman has revealed he is "feeling fit as a fiddle" after requiring emergency heart treatment.