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HIV integrase inhibitors

The disclosure generally relates to the novel compounds of formula I, including their salts, which inhibit HIV integrase and prevent viral integration into human DNA. This action makes the compounds useful for treating HIV infection and AIDS. The invention also encompasses pharmaceutical compositions and methods for treating those infected with HIV.




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ARCHIVE PIC OF THE DAY: Fantastic picture of vessel with gaping hole

THE crippled Greek cargo ship Nymfea was brought to Southampton docks for urgent repairs following a collision with another vessel in the English Channel nearly 55 years ago.




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ARCHIVE PIC OF THE DAY: Fantastic group shot shows stevedores in fancy dress

PARKER’S Hotel, at the junction of Terminus Terrace and Bridge Road in Southampton – now the lower end of Bernard Street – is the backdrop for this 1906 photograph.




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ARCHIVE PIC OF THE DAY: Workmen repaint Queen Mary after Second World War

DWARFED by the huge size of one of Queen Mary’s three funnels, a team of workmen repaint the smokestack as part of the ship’s refit more than 70 years ago.




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No Dough Music launches The Archive, free Underground Electronics for Ableton Live available

No Dough Music has announced its new online House/Techno/Electronic music production hub The Archive, which features content from all of No Dough’s current sample packs repackaged with loads of new features. The Archive will offer sound packs, Ableton projects, production technique and how to blogs, podcasts, interviews, and video content. Available now, Underground Electronics is […]

The post No Dough Music launches The Archive, free Underground Electronics for Ableton Live available appeared first on rekkerd.org.




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Neural 58, Archivism (the dynamics of archiving)

Issue #58, Autumn 2017 ISSN: 2037-108X

The new Neural issue is hot from the press.

Subscribe now! because only subscribers will get a free Cyanometer by Martin Bricelj Baraga.

You can also subscribe to the magazine Digital Edition accessing all issues since #29.




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Some Push To Change State Laws That Require HIV Disclosure To Sexual Partners

In more than 30 states, it is illegal for someone with HIV to have sex without first disclosing their status. Some are now pushing to change that, arguing that the laws are actually endangering public health. More than 1 million people in the U.S. are living with HIV, and their HIV status could conceivably put them behind bars. That's what happened to Michael Holder. "I served 8 1/2 years in prison and three years after on parole," Holder says. Back in 2000, Holder's ex-girlfriend testified that he didn't disclose his HIV status before they had sex. That's a crime in Michigan and in most states in the country. He says the day after she said that, she came in and recanted. "She testified the truth and said that she had lied and said that she was jealous, and she loved me and that I had told her just like I had testified and said I'd told her," Holder says. "And she told the truth, but it was too late." Holder couldn't prove that he told her. Public health experts say that's one of many




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Art From The Archives: 5 "On Second Thought" Segments To Revisit

On this week’s return to our archives, On Second Thought is presenting some of our favorite arts and media stories. From movies to “Mobituaries,” motivate your Monday with some memorable pieces from yesteryear. 1) First, She Got Oprah's Attention. Now, She's On Netflix. What Will Kyanna Simone Simpson Do Next? Decatur native and University of Georgia graduate Kyanna Simone Simpson has seen a meteoric rise in the last few years. She stars in Netflix’s Chambers , as well as Ma (2019) alongside Octavia Spencer, the CW’s Black Lightning , and The Immortal Life of Henrietta Lacks (2017), a HBO biopic. Her career caught the attention of Oprah Winfrey, who cast Simone Simpson in her own biopic. She joined On Second Thought and reflected on media representation and her own experiences in the industry. 2) Pat Mitchell On 'Becoming A Dangerous Woman' — And The Importance Telling Their Stories Pat Mitchell is a massive name in the news industry — as president of CNN Productions and the first




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Archive-It Crawl Data: Partner 1028 Collection 12729 Crawl Job 1150088

No description available.

This item belongs to: web/ArchiveIt-Collection-12729.

This item has files of the following types: Metadata



  • web/ArchiveIt-Collection-12729

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Archive-It Crawl Data: Partner 920 Collection 14068 Crawl Job 1150292

No description available.

This item belongs to: web/ArchiveIt-Collection-14068.

This item has files of the following types: Metadata, Web ARChive GZ



  • web/ArchiveIt-Collection-14068

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Archive-It Crawl Data: Partner 1028 Collection 12734 Crawl Job 1149990

No description available.

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This item has files of the following types: Metadata



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Archive-It Crawl Data: Partner 1028 Collection 8142 Crawl Job 1150203

No description available.

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  • web/ArchiveIt-Collection-8142

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Archive-It Crawl Data: Partner 1028 Collection 13346 Crawl Job 1150238

No description available.

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  • web/ArchiveIt-Collection-13346

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Archive-It Crawl Data: Partner 1028 Collection 12734 Crawl Job 1149990

No description available.

This item belongs to: web/ArchiveIt-Collection-12734.

This item has files of the following types: Metadata



  • web/ArchiveIt-Collection-12734

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Archive-It Crawl Data: Partner 1028 Collection 13842 Crawl Job 1150162

No description available.

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This item has files of the following types: Metadata



  • web/ArchiveIt-Collection-13842

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Archive-It Crawl Data: Partner 920 Collection 14068 Crawl Job 1150292

No description available.

This item belongs to: web/ArchiveIt-Collection-14068.

This item has files of the following types: Metadata



  • web/ArchiveIt-Collection-14068

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RAVEL, M.: Miroirs / La valse / Le tombeau de Couperin (Idil Biret Archive Edition, Vol. 19) (8.571404)








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Government's drug testing plan slammed by medical experts, compared to mooted Kremlin HIV strategy

Drug experts and welfare groups speak out against the Government's push to drug test welfare recipients, questioning why the bill has been revived despite "comprehensive" opposition from the medical profession.



  • ABC Radio Perth
  • perth
  • Community and Society:All:All
  • Community and Society:Drugs and Substance Abuse:All
  • Community and Society:Welfare:All
  • Government and Politics:All:All
  • Government and Politics:Federal Government:All
  • Australia:All:All
  • Australia:WA:Mandurah 6210

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Cold snap to send shivers across Queensland

Cooler-than-average temperatures are likely to be felt in southern and central Queensland from today as a cold front works its way through the state.








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Honey producers hand-feed bees during drought to save hives, with sting likely for consumers

Beekeepers in New South Wales are hand-feeding their hives as the drought cripples the bees' ability to make honey, with a shortage expected to sting consumers at the checkout.






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BOM's hot April data may be surprising to those currently shivering

As the south and east remain gripped in a cold snap, it might be hard to believe that Australia just had its fifth warmest April on record.





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Chalkbrood fungal disease on the rise in Australian beehives and poor nutrition could be to blame

A disease is wreaking havoc on Australian beehives, and one PhD student and beekeeper is trying to find out why.




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Stories of the Stolen Generations preserved in Bringing Them Home archive at National Library

The stories of the Stolen Generations told in their own voices are preserved in a unique audio archive at the National Library.




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Silent film star Louise Lovely's 1916 fan letter and photos acquired by National Archive

The National Film and Sound Archive acquires photos and a letter sent to fans by silent movie star Louise Lovely.




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Model FJ Holden panel van commemorates newsreel era at National Film and Sound Archive

A vintage FJ Holden panel van is commemorating the daring feats of newsreel crews in the 1940s and 50s when news was served at the movies.




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National Archives to display Apollo II moon rocks on 50th anniversary of moon landing

Fragments of moon rock and an Australian flag sent into space will go on public display next year to celebrate the 50th anniversary of the lunar landing.






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John Farnham, Olivia Newton-John and Savage Garden added to official Sounds of Australia archive

What do John Farnham, Olivia Newton-John and Savage Garden all have in common? Apart from producing bona-fide pop bangers, they've all just been added to the official Sounds of Australia archive.



  • ABC Radio Canberra
  • canberra
  • Arts and Entertainment:All:All
  • Arts and Entertainment:Music:All
  • Arts and Entertainment:Music:Australian Composers
  • Arts and Entertainment:Music:Bands and Artists
  • Arts and Entertainment:Music:Composer
  • Arts and Entertainment:Poetry:All
  • Arts and Entertainment:Popular Culture:All
  • Australia:ACT:All
  • Australia:ACT:Canberra 2600

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HIV and hepatitis C risk to patients as Cairns dental clinic closed by health authorities

Health authorities urge more than 500 patients of a dental clinic in Far North Queensland to be tested for HIV and hepatitis as the clinic is investigated over its infection control practices.




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Queensland shivers through coldest morning of the year

A cold dry air mass moving through the state is causing cool mornings in Queensland, with temperatures dropping as low as -4.8 degrees Celsius, and it's forecast to continue throughout the week.




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Eve van Grafhorst was diagnosed with HIV and hounded out of Australia, but her legacy endures

Eve van Grafhorst was almost three when she was diagnosed with HIV in 1985. Then she was banned from childcare, and eventually her family was hounded to New Zealand where they started a new life.




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Webinar: Labanotation Archives at The Ohio State University

Labanotation Archives at The Ohio State University Wednesday, May 6, 2020 11 a.m. – noon EST Register here Join us for a virtual experience of dance notation in the archives at Ohio State. Labanotation, a symbol system for movement preservation and transmission, is a strong presence in University Library Special Collections, interwoven into the history of OSUDance, […]




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Telling Stories about the Byrd Second Antarctic Expedition: Findings from the Byrd Archives Webinar

Telling Stories about the Byrd Second Antarctic Expedition: Findings from the Byrd Archives  Wednesday, May 13, 2020 3 – 4 p.m. EST Register here Join the Byrd Center in a virtual webinar with Dr. Anneke Schwob from the University of North Carolina at Chapel Hill. This is a special seminar and collaboration between the Byrd Center and Polar […]




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The fruits of our labor - Eloarei - 僕のヒーローアカデミア | Boku no Hero Academia | My Hero Academia [Archive of Our Own]

Aside from a few wild guesses, Izuku had no idea how this had happened. But here he was, about to bear All Might's child, and all he could think to blame it on was a jar of rice.




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Criticidades» Archivo del BlogValor y negación del Nirvana. Sin fase uno. - Criticidades

via Criticidades https://ift.tt/1RabwUr




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Empty sets - BBC Archive

"Give your video calls a makeover, with this selection of over 100 empty sets from the BBC Archive." Very good. (via @wonderlandblog)




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Heimlich v. Shivji

(Supreme Court of California) - Clarified how California Code of Civil Procedure section 998 (relating to pretrial settlement offers) is used in arbitration. Held a request for costs under that provision is timely if filed with the arbitrator within 15 days of a final award. In response to such a request, an arbitrator has authority to award costs to the offering party. However, if an arbitrator refuses to award costs, judicial review is limited.



  • Dispute Resolution & Arbitration

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Heimlich v. Shivji

(Supreme Court of California) - Clarified how California Code of Civil Procedure section 998 (relating to pretrial settlement offers) is used in arbitration. Held a request for costs under that provision is timely if filed with the arbitrator within 15 days of a final award. In response to such a request, an arbitrator has authority to award costs to the offering party. However, if an arbitrator refuses to award costs, judicial review is limited.



  • Dispute Resolution & Arbitration