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DNA-compatible functional group transformations via K2RuO4-mediated oxidation

Org. Chem. Front., 2024, Advance Article
DOI: 10.1039/D4QO00203B, Research Article
Pengyang He, Guixian Zhao, Mengping Zhu, Yangfeng Li, Gong Zhang, Yizhou Li
K2RuO4-mediated oxidation offers a DNA-compatible method for functional group transformations, enabling alcohol-to-carboxylic acid and amine-to-nitrile conversions valuable for DNA-encoded library synthesis.
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Recent advances in the metal-catalyzed asymmetric alkene hydrogenation of cyclic conjugated carbonyl compounds

Org. Chem. Front., 2024, Advance Article
DOI: 10.1039/D4QO00227J, Review Article
Min Tan, Bram B. C. Peters, Pher G. Andersson, Taigang Zhou
This review summarizes the recent advances (2016–2023) in the stereoselective metal-catalyzed hydrogenation of cyclic α,β-unsaturated ketones, lactams and lactones since considerable developments were made. Where possible the application of these methodologies in synthesis is outlined.
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Computational insights into the synergistic interplay of ligand and fluorine effects in palladium-catalyzed regiodivergent decarboxylative allylic alkylation

Org. Chem. Front., 2024, Advance Article
DOI: 10.1039/D4QO00147H, Research Article
Shiyu Wang, Hongli Wu, Xiangyang Tang, Genping Huang
DFT calculations were performed to investigate palladium-catalyzed decarboxylative allylic alkylation of allyl difluoro-β-ketoesters. The synergistic effects of ligand and fluorine substituents on regioselectivity were uncovered.
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Review of application of the I2 and dimethyl sulfoxide combined reagent system to aryl methyl ketones for diverse transformations

Org. Chem. Front., 2024, Advance Article
DOI: 10.1039/D4QO00396A, Review Article
Dong-Sheng Yang, Xiang-Long Chen, An-Xin Wu
The synthesis of small molecules and complex scaffolds is one of the most important topics in organic synthesis.
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Vaska's complex–PMHS combination enabled mild and chemoselective reduction of sulfoxides to sulfides with low catalyst loading

Org. Chem. Front., 2024, Advance Article
DOI: 10.1039/D4QO00312H, Research Article
Fang-Fang Xu, Zhong-Lei Ruan, Pei-Qiang Huang
We report a highly efficient, versatile, and chemoselective method for the catalytic reduction of sulfoxides to sulfides under mild conditions.
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Three-component Friedel–Crafts-type difunctionalization of ynamides with (hetero)arenes and iodine(III) electrophile

Org. Chem. Front., 2024, Advance Article
DOI: 10.1039/D4QO00489B, Research Article
Open Access
Jun Kikuchi, Toya Nagata, Shingo Ito, Naohiko Yoshikai
A three-component Friedel–Crafts type difunctionalization of ynamides with an iodine(III) electrophile and electron-rich (hetero)arenes has been developed, enabling regio- and stereoselective synthesis of densely functionalized enamides.
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Electron donor–acceptor complex photoactivation for deaminative alkynylation, alkenylation and allenylation: a comprehensive study

Org. Chem. Front., 2024, 11,2231-2240
DOI: 10.1039/D4QO00177J, Research Article
Romain Lapierre, Lina Truong, Matthieu Hedouin, Hassan Oulyadi, Bruno Schiavi, Alexandre Jean, Philippe Jubault, Thomas Poisson
Herein, we disclose our study toward photoinduced deaminative alkynylation, alkenylation and allenylation.
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Thiourea as a precatalyst for the electron donor–acceptor complex photoactivation platform of oxime esters

Org. Chem. Front., 2024, Advance Article
DOI: 10.1039/D4QO00424H, Research Article
Haichen Mao, Yuting Zhang, Hengrong Cao, Qianqian Shi, Yu Lan, Junbiao Chang, Bo Zhu
A novel electron donor–acceptor (EDA) complex catalysis strategy has been developed using thiourea as a precatalyst under blue LED irradiation. Using 2–5 mol% of thiourea, various nitrogen-containing compounds were successfully synthesized.
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Centre releases ₹266.8 crore under 15th Finance Commission grants for rural local bodies in Kerala

Allocation represents second instalment of untied grants for 2024-25, and is meant for all eligible district panchayats, block panchayats and gram panchayats in Kerala




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Thiruvananthapuram Zoo welcomes new species from Shivamogga

Arrival of hyenas, jackals, marsh crocodiles, and palm civets raise species count to 94




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Quiz competition on AI in Karunagapally




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Women’s Commission sitting held in Kollam




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Coast Guard Chief S Paramesh calls on India's High Commissioner to Sri Lanka, discusses maritime security




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Gujarat: Consumers can lodge electricity-related complaints online at any time




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Autocomplete Interview - Megan Thee Stallion Answers The Web's Most Searched Questions

Musician Megan Thee Stallion visits WIRED to answer her most searched for questions on Google. Where did Megan Thee Stallion get her name? What's her favorite anime? What is Megan Thee Stallion's typical workout routine? What does Megan Thee Stallion call her fans? Answers to these questions and many more await on the WIRED Autocomplete Interview. 'Megan Thee Stallion: In Her Words' is now streaming on Prime Video. Megan Thee Stallion's deluxe album 'Megan: Act II" is now available to stream. Director: Justin Wolfson Director of Photography: Kevin Dynia Editor: Daniel Poler Talent: Megan Thee Stallion Line Producer: Joseph Buscemi Associate Producer: Brandon White; Paul Gulyas Production Manager: Peter Brunette Production Coordinator: Rhyan Lark Talent Booker: Jenna Caldwell Camera Operator: Caleb Weiss Sound Mixer: Michael Guggino Production Assistant: Ryan Coppola Post Production Supervisor: Christian Olguin Post Production Coordinator: Ian Bryant Supervising Editor: Doug Larsen Additional Editor: Jason Malizia Assistant Editor: Justin Symonds




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Photothermal conversion enabled temperature modulation for the growth of complex polymorphic architectures of calcium carbonate

J. Mater. Chem. A, 2024, Accepted Manuscript
DOI: 10.1039/D4TA00802B, Paper
Boning Shi, Lifu Zhang, Zeda Yang, Jiangnan Deng, Shun An, Benwei Fu, Chengyi Song, Peng Tao, Tao Deng, Wen Shang
As a highly efficient and eco-friendly heat generation approach, photothermal conversion process has been applied to many important areas such as desalination and medical treatments. We explored in this work...
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Reduction on Specific Lattice Planes for Metal-organic Frameworks/Poly-pyrrole Composites with Dilated Porosity

J. Mater. Chem. A, 2024, Accepted Manuscript
DOI: 10.1039/D4TA00766B, Paper
Wenxiu He, Xu Zhai, Zhipeng Qiao, Huan Chen, Weiliang Tian, Yu Fu, Junyi Chen
Owing to the microporosity, metal-organic frameworks (MOFs) have attracted great attention in various applications, whereas their potential in mass transfer and diffusion of larger molecules have been limited. To break...
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A heterostructured WO3–SnO2 nanocomposite for the efficient photocatalytic production of H2O2 under visible light

J. Mater. Chem. A, 2024, Advance Article
DOI: 10.1039/D4TA01223B, Paper
Diya Xie, Chen Chen, Yaru Wang, Cheng Sun, Yiming Xu, Jianguo Huang
A WO3–SnO2 (WSN) nanocomposite was synthesized with unique heterostructures formed in-between the two phases, resulting in the efficient production of H2O2 under visible light due to the synergistic effect.
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Cubic-to-hexagonal Structural Phase Transition in Metal Halide Compounds: A DFT Study

J. Mater. Chem. A, 2024, Accepted Manuscript
DOI: 10.1039/D3TA06604E, Paper
Iván Ornelas-Cruz, Ramiro M. dos Santos, José E. González, Matheus Paes Lima, Juarez L. F. Da Silva
Phase transitions into photo-inactive structural phases have impacted the use of metal halide perovskites as photovoltaic materials. However, the chemical composition has been found to mitigate this issue. This study...
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Molecular-polaron-coupling-enhanced photocatalytic CO2 reduction on copper phthalocyanine/NiMgFe layered double hydroxide nanocomposites

J. Mater. Chem. A, 2024, Advance Article
DOI: 10.1039/D3TA07538A, Paper
Yuexian Li, Wenli Su, Xiaoyan Wang, Jun Lu, Wenkai Zhang, Shuo Wei
We built CuPcS/NiMgFe-LDHs composites and probed the unique photogenerated-carrier transfer mechanism. A series of long-range Forster energy transfers prolonged the lifetime of photogenerated carriers to match the timescale of surface reaction.
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Machine Learning Enabled Exploration of Multicomponent Metal Oxides for Catalyzing Oxygen Reduction in Alkaline Media

J. Mater. Chem. A, 2024, Accepted Manuscript
DOI: 10.1039/D4TA01884B, Paper
Open Access
  This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.
Xue Jia, Hao Li
Low-cost metal oxides have emerged as promising candidates used as electrocatalysts for oxygen reduction reaction (ORR) due to their remarkable stability under oxidizing conditions, particularly in alkaline media. Recent studies...
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Highly selective and high-performance sulfonated poly(ether ether ketone)-based hybrid membrane enabled by complexed UiO-66-NH2 and sulfonated graphitic carbon nitride for vanadium flow battery

J. Mater. Chem. A, 2024, Accepted Manuscript
DOI: 10.1039/D4TA00988F, Paper
Caiyuan Zhao, Haixia Wang, Lang Li, Liping Liu, Xinrui Cui, Haifeng Shi
A series of sulfonated poly(ether ether ketone) (SPEEK) hybrid membranes (SPEEK/NF) with a constant 1 wt% complexed nanofillers (NF) comprising of UiO-66-NH2 and sulfonated graphitic carbon nitride (s-g-C3N4) are prepared...
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Breaking the Trade-off Between ∆EST and Oscillator Strength in Hybrid LR/SR-CT Compounds for Enhanced TADF Performance

J. Mater. Chem. C, 2024, Accepted Manuscript
DOI: 10.1039/D4TC04549A, Paper
Nikhitha R., Anirban Mondal
Achieving an ideal thermally activated delayed fluorescence (TADF) emitter requires balancing a minimal singlet-triplet energy gap (∆EST) with a considerable oscillator strength (f), which are typically mutually exclusive. By strategically...
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A cafe in Coimbatore pays an ode to the riding community with a nutritious menu




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Supreme Court verdict on bulldozer demolitions: Jamiat hails verdict, victims seek compensation

It is a significant step towards safeguarding the rule of law and fundamental rights of citizens, say Jamiat leaders




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Omar seeks compensation from Centre over losses due to Indus Water Treaty

Jammu and Kashmir Chief Minister’s remarks that the IWT hinders J&K’s power capacity spark row; the focus should be the return of power projects from National Hydroelectric Power Corporation, says former Chief Minister Mehbooba Mufti




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Google.org awards USD 1 mn grant to Karya to boost ai-based economic opportunities for low-income communities




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FSSAI discusses various sets of compliances with e-commerce food operators




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India set to become 'major producer' of electric vehicles like China: Mark Mobius




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Air India completes merger with Vistara




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‘Anti-war’ comedy play riles Bulgarian nationalists

Last week’s premiere of Arms and the Man by renowned Irish-born playwright George Bernard Shaw sparked raucous protests by nationalist groups




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COP29: India, other developing countries demand fair climate finance commitments

India, LMDCs advocate for equitable climate finance at COP29, pushing for transparency, fairness, and flexibility in financial commitments




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New ATP-competitive inhibitors of E. coli GyrB obtained from the mapping of the hydrophobic floor at the binding site: synthesis and biological evaluation

RSC Med. Chem., 2024, 15,3759-3777
DOI: 10.1039/D4MD00498A, Research Article
Lucas Gutierrez, Peter Peršolja, Rodrigo Tosso, Nace Zidar, Danijel Kikelj, Ricardo D. Enriz
A diagram of the active site of E. coli gyrase B, highlighting the hydrophobic subsite, including key residues relevant to ligand binding.
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Prediction of synergistic gemcitabine-based combination treatment through a novel tumor stemness biomarker NANOG in pancreatic cancer

RSC Med. Chem., 2024, 15,3853-3861
DOI: 10.1039/D4MD00165F, Research Article
Jiongjia Cheng, Ting Zhu, Shaoxian Liu, Jiayu Zhou, Xiaofeng Wang, Guangxiang Liu
The synergistic effect observed in gemcitabine-based combination therapies targeting pancreatic cancer stem cells was correlated with the inhibiting effect on the expression of stemness-related gene NANOG.
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Correction: computational design, synthesis, and assessment of 3-(4-(4-(1,3,4-oxadiazol-2-yl)-1H-imidazol-2-yl)phenyl)-1,2,4-oxadiazole derivatives as effective epidermal growth factor receptor inhibitors: a prospective strategy for anticancer therapy

RSC Med. Chem., 2024, 15,3912-3912
DOI: 10.1039/D4MD90040E, Correction
Open Access
  This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.
Nilesh Raghunath Khedkar, Milind Sindkhedkar, Alex Joseph
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Anticancer potential of copper(I) complexes based on isopropyl ester derivatives of bis(pyrazol-1-yl)acetate ligands

RSC Med. Chem., 2024, Accepted Manuscript
DOI: 10.1039/D4MD00610K, Research Article
Open Access
Maura Pellei, Carlo Santini, Miriam Caviglia, Jo' Del Gobbo, Chiara Battocchio, Carlo Meneghini, Simone Amatori, Chiara Donati, Eleonora Zampieri, Valentina Gandin, Cristina Marzano
In this paper, the isopropyl ester derivatives LOiPr and L2OiPr of bis(pyrazol-1-yl)acetic acid and bis(3,5-dimethyl-pyrazol-1-yl)acetic acid were used as chelators for the preparation of the new Cu(I) phosphane complexes 1-4....
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Four Swedish companies, including IKEA, looking to set up base in Tamil Nadu: Swedish Ambassador to India

There are 70 Swedish companies in Tamil Nadu, employing about 25,000 people. But we want to do more, says Jan Thesleff




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RLDA invites bids for commercial land use in Tirupati railway station

The station is being developed on a massive scale, providing commuting area on the southern side, in view of the crammed locality on the northern side




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Andhra Pradesh govt. reaffirms commitment to ‘irrigating every acre of farmland’ in State through river-interlinking projects




com

COP29: India, other developing countries demand fair climate finance commitments

India, LMDCs advocate for equitable climate finance at COP29, pushing for transparency, fairness, and flexibility in financial commitments




com

Millions of Nigerians go hungry as floods compound hardship

Torrential rains and floods in 29 of Nigeria's 36 states this year have destroyed more than 1.5 million hectares of cropland, affecting more than nine million people




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Why US chess champ Levon Aronian is connecting with the Armenian community in Chennai

Chess champion Levon Aronian, who competed in Chennai Grand Masters recently, on future Indian chess superstars




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Comeback man Shami hogs the spotlight as MP takes honours on opening day against Bengal




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29th IFFK: organising committee formed




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KSRTC invites EoI to ready commercial complex at Ernakulam depot




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Comeback man Shami makes a quiet return to action

Aryan and Khejroliya pick up four wickets apiece as Madhya Pradesh bowls out Bengal for 228; host batters build on advantage




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Year-long action plan to combat diabetes to be launched on World Diabetes Day




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Cochin Shipyard funding for climate tech company




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Nagamohan Das to head panel to suggest internal reservation among SC communities




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CMC organises exhibition and poster competition on diabetes