1. With more young obese patients, focus now on diabetes reversal  The Times of India
2. Does Diabetes Impact Mental Well-being? 5 Key Insights You Need to Know, According To Doctor  HerZindagi English
3. 86% diabetics in India facing anxiety, depression; women more affected: Report  Gujarat Samachar
4. Diabetes affects mental well-being of more than 4 in 5 Indians living with conditions, IDF survey reveals  The Financial Express
5. Diabetes-related Depression: How to work your way around the two Ds  Mint

Media mogul was found guilty of rape in 2020, but his conviction was overturned in April due to unfair trial concerns

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Earth's magnetic field seems steady and true -- reliable enough to navigate by. Yet, largely hidden from daily life, the field drifts, waxes and wanes. The magnetic North Pole is currently shifting toward Siberia, forcing the Global Positioning System that underlies modern navigation to update its software sooner than expected. Every several hundred thousand years, the magnetic field dramatically shifts and reverses its polarity. Magnetic north flips to the geographic South Pole and, eventually, back again. This reversal has happened countless times over Earth's history, but scientists' understanding of why and how the field reverses is limited. The researchers find that the most recent field reversal 770,000 years ago took at least 22,000 years to complete, several times longer than previously thought. The results call into question controversial findings that some reversals could occur within a human lifetime.

Image credit: Brad Singer

A New York appellate court ruled that a worker was not entitled to summary judgment on one aspect of his Labor Law claim. Case: Urquia v. Deegan 135 Realty LLC,  No. 22340/19,…

In the wake of the election, sweeping policy shifts in the information economy are set to accelerate. Expect fast-tracked FCC reforms, Starlink subsidies, and AI-driven oversight to redefine media, tech, and regulatory landscapes. From relaxed antitrust to intensified media control, these eleven reversals signal a move toward deregulation and Chicago School libertarianism, with lasting impacts on U.S. markets and governance.

Jordan Daniels has worked in the Atlanta film industry for years. Monday's court ruling, which reversed the controversial "heartbeat" abortion bill passed last year in Georgia, came as a relief. "We did have a few productions leave on the basis of HB 481, and I'm happy that more won't," she said. "Obviously, I'm dually relieved since I'm a woman who loves her job, and also wants the right to choose."

Updated at 4 p.m. ET Months after approving some limited involvement by the Chinese technology giant Huawei in constructing the U.K.'s next-generation wireless data network, British regulators reversed course Tuesday. Beginning in January, U.K. regulators will implement a ban on telecom operators buying Huawei equipment. Existing Huawei 5G equipment will need to be removed from the U.K.'s 5G network by 2027. The decision comes after relations between the U.K. and China declined sharply over China's actions in Hong Kong, and in the face of a potential rebellion by parliamentarians from the U.K.'s ruling Conservative party who are concerned about the security implications of Chinese involvement in the 5G rollout. But it also follows sustained U.S. pressure on the U.K. and other European countries to exclude Huawei from 5G development. The U.S. says Huawei's equipment can be used for espionage by Beijing, and it has threatened to withhold intelligence from its allies that continued to use

Customers now have access to Google’s homegrown hardware — its Axion CPU and latest Trillium TPU — in its Cloud service.  At the same time, Google gave customers a teaser […]

The post Role Reversal: Google Teases Nvidia’s Blackwell as It Softens TPU Rivalry appeared first on HPCwire.

A team at the Paul Scherrer Institute (PSI) has achieved a breakthrough with the Kagome superconductor RbV3Sb5, demonstrating time-reversal symmetry (TRS) breaking at 175 Kelvin. This discovery at higher temperatures than typically possible could pave the way for more energy-efficient and practical quantum systems, crucial for quantum computing and storage. The TRS-breaking properties are tunable, offering potential for further advancements in quantum technology, with implications for applications beyond laboratory settings.

FDI into Brazil has increased by 66.48% in a little under two years. Jonathan Wildsmith reports.

Mitochondrial dysfunction is a hallmark of many genetic neurodegenerative diseases, but therapeutic options to reverse mitochondrial dysfunction are limited. While recent studies support the possibility of improving mitochondrial fusion/fission dynamics and motility to correct mitochondrial dysfunction and resulting neurodegeneration in Charcot-Marie-Tooth disease (CMT) and other neuropathies, the clinical utility of reported compounds and relevance of preclinical models are uncertain. Here, we describe motor and sensory neuron dysfunction characteristic of clinical CMT type 2 A in a CRISPR/Casp-engineered Mfn2 Thr105Met (T105M) mutant knock-in mouse. We further demonstrate that daily oral treatment with a novel mitofusin activator derived from the natural product piperine can reverse these neurologic phenotypes. Piperine derivative 8015 promoted mitochondrial fusion and motility in Mfn2-deficient cells in a mitofusin-dependent manner and reversed mitochondrial dysfunction in cultured fibroblasts and reprogrammed motor neurons from a human CMT2A patient carrying the MFN2 T105M mutation. Like previous mitofusin activators, 8015 exhibited stereospecific functionality, but the more active stereoisomer, 8015-P2, is unique in that it has subnanomolar potency and undergoes entero-hepatic recirculation which extends its in vivo half-life. Daily administration of 8015-P2 to Mfn2 T105M knock-in mice for 6 weeks normalized neuromuscular and sensory dysfunction and corrected histological/ultrastructural neurodegeneration and neurogenic myoatrophy. These studies describe a more clinically relevant mouse model of CMT2A and an improved mitofusin activator derived from piperine. We posit that 8015-P2 and other piperine derivatives may benefit CMT2A or other neurodegenerative conditions wherein mitochondrial dysdynamism plays a contributory role.

Someone tried using the gender-swap filter on a few Bollywood actors and the results will surely amaze you to the core.

It functions by directing the thrust produced by the plane’s jet engines forward, rather than backwards

UNITED NATIONS: The United States on Friday stunned other members of the UN Security Council by preventing a vote on a resolution for a ceasefire in various conflicts around the world to help troubled nations better fight the coronavirus pandemic, diplomats said.Washington´s reversal came a...

UNITED NATIONS: The United States on Friday stunned other members of the UN Security Council by preventing a vote on a resolution for a ceasefire in various conflicts around the world to help troubled nations better fight the coronavirus pandemic, diplomats said.Washington’s reversal came a...

China and the United States both supported a draft United Nations Security Council resolution confronting the coronavirus pandemic on Thursday and it was "shocking and regretful" that Washington changed its mind on Friday, a Chinese diplomat said.

China and the United States both supported a draft United Nations Security Council resolution confronting the coronavirus pandemic on Thursday and it was "shocking and regretful" that Washington changed its mind on Friday, a Chinese diplomat said.

For more than six weeks the 15-member council has been trying to agree on a text that ultimately aims to back a March 23 call by U.N. chief Antonio Guterres for a ceasefire in global conflicts so the world can focus on the pandemic.

Washington has halted funding for the WHO, a UN agency, after President Donald Trump accused it of being "China-centric" and promoting China's "disinformation" about the outbreak, assertions the WHO denies.

China and the United States both supported a draft United Nations Security Council resolution confronting the coronavirus pandemic on Thursday and it was "shocking and regretful" that Washington changed its mind on Friday, a Chinese diplomat said.

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Earth's magnetic field seems steady and true -- reliable enough to navigate by. Yet, largely hidden from daily life, the field drifts, waxes and wanes. The magnetic North Pole is currently shifting toward Siberia, forcing the Global Positioning System that underlies modern navigation to update its software sooner than expected. Every several hundred thousand years, the magnetic field dramatically shifts and reverses its polarity. Magnetic north flips to the geographic South Pole and, eventually, back again. This reversal has happened countless times over Earth's history, but scientists' understanding of why and how the field reverses is limited. The researchers find that the most recent field reversal 770,000 years ago took at least 22,000 years to complete, several times longer than previously thought. The results call into question controversial findings that some reversals could occur within a human lifetime.

Image credit: Brad Singer

Small sellers on e-commerce platforms said they are faced with a working capital crunch and the delay would force them to pay partial or no salaries for April.

After a drubbing in the media, the formerly popular brand is making amends.

The magnetic pole is moving faster than at any time in human history, causing major problems for navigation and migratory wildlife.

Low-level Light Therapy Provides a No Drug Approach to a Chronic Condition

Randall D. Eliason: The government's motion to dismiss the case against former national security adviser Michael Flynn is like nothing I've ever seen. It's a political screed dressed up as legal analysis, promoting the "deep state" conspiracy fantasies of President Trump. It epitomizes the politicization of the Justice Department under Attorney General William P. Barr. It is, in the truest sense of the word, lawless.

A circuit (C1-C4) is employed in a TWACS transponder (T) installed in an electric meter (M). The transponder generates inbound signals (IB) transmitted from the location of the electric meter to a central location (R). Firmware (F) within the transponder controls the flow of current for each pulse through the circuit by triggering a semi-conductor device such as a SCR (X1) or TRIAC (X2). The resulting current flow through the inductor for a subsequent pulse, regardless of the pulse's polarity, will be in the opposite direction to that of the previous pulse. The result is to maintain a constant level of magnetization of the inductor core which does not have to be overcome by energy in the subsequent pulse resulting in amplitude of all the pulses imposed on an AC waveform being substantially the same.

Efficiency of a switch mode power supply (SMPS) is optimized by operating the SMPS in an asynchronous mode when current being supplied therefrom is less than a certain current value and operating the SMPS in a synchronous mode when the current being supplied therefrom is equal to or greater than the certain current value. When the SMPS is operating in the synchronous mode high-side and low-side power transistors alternately turn on and off. When the SMPS is operating in the asynchronous mode only the high-side power transistor turns on and off and the low-side power transistor remains off. When charging a battery with the SMPS discharge of the battery is eliminated when operating in the asynchronous mode at a low current output.

A time-reversal wireless system comprising a first wireless transceiver of a time-reversal client, one or more second wireless transceiver and/or a time-reversal client with the first wireless transceiver. The first wireless transceiver of the time-reversal client is wirelessly coupled to the one or more second wireless transceiver through a wireless broadband multipath channel associated with a space. The time-reversal client contains the first wireless transceiver. The time-reversal client also contains a processor and a memory configured to obtain a set of channel state information (CSI) in a channel probing phase, and/or to obtain a set of location-specific signatures based on the set of CSI and/or a time reversal operation in a channel probing phase. The set of CSI is captured when one or more probing signal is sent either from the first wireless transceiver to each of the at least one second wireless transceiver, or from each of the at least one second wireless transceiver to the first wireless transceiver, through the wireless broadband multipath channel associated with the space. A channel passband with bandwidth W0 is associated with the wireless broadband multipath channel. A first passband with bandwidth W1 is associated with the first wireless transceiver. The W1 is not larger than W0 such that the first passband is part of the channel passband. One or more second passband is associated with the one or more second wireless transceiver such that a bandwidth W2 associated with each of the one or more second passband is not larger than W1 such that the each of the one or more second passband is part of the first passband. Each of the set of CSI include a channel impulse response, a channel frequency response, and/or another channel state data of the wireless broadband multipath channel.

Technologies for streaming device role reversal include a source computing device and a destination computing device coupled via a communication channel. The source computing device and destination computing device are each configured to support role reversal. In other words, the source computing device and the destination computing device are each capable of switching between receiving and transmitting digital media content over the established communication channel. The source computing device is configured to initiate the role reversal, pause transmit functionality of the source computing device, and enable receive functionality of the source computing device. The destination computing device is configured to receive a role reversal indication from the source computing device, locally process the content, transmit a content stream to the source computing device, and display the content stream on an output device of the source computing device. Other embodiments are described and claimed herein.

Walter Goudy, 51, reached a settlement with the city of Anderson and the state of Indiana, according to city officials and and his attorney.

FDI into Brazil has increased by 66.48% in a little under two years. Jonathan Wildsmith reports.

The United States stunned other members of the UN Security Council by preventing a vote on a resolution for a ceasefire in various conflicts around the world to help troubled nations better fight the coronavirus pandemic, diplomats said.

The United States has stunned other members of the UN Security Council by preventing a vote on a resolution for a ceasefire in various conflicts around the world to help troubled nations better fight the coronavirus pandemic, diplomats said.Washington’s reversal on Friday came a day after it agreed to the text, negotiators said under cover of anonymity.“The United States cannot support the current draft,” the country’s delegation declared, without further detail, to the 14 other Security…

Although pain is a prevalent nonmotor symptom in Parkinson’s disease (PD), it is undertreated, in part because of our limited understanding of the underlying mechanisms. Considering that the basal ganglia are implicated in pain sensation, and that their synaptic outputs are controlled by the subthalamic nucleus (STN), we hypothesized that...

Krishnamoorthy Krishnan, Asif Shahriar Nafi, Roi Gurka, and Roi Holzman

Fish larvae are the smallest self-sustaining vertebrates. As such, they face multiple challenges that stem from their minute size, and from the hydrodynamic regime in which they dwell. This regime, of intermediate Reynolds numbers, was shown to affect the swimming of larval fish and impede their ability to capture prey. Prey capture is impeded because smaller larvae produce weaker suction flows, exerting weaker forces on the prey. Previous observations on feeding larvae also showed prey exiting the mouth after initially entering it (hereafter "in-and-out"), although the mechanism causing such failures had been unclear. In this study, we used numerical simulations to investigate the hydrodynamic mechanisms responsible for the failure to feed caused by this in-and-out prey movement. Detailed kinematics of the expanding mouth during prey capture by larval Sparus aurata were used to parameterize age-specific numerical models of the flows inside the mouth. These models revealed that for small larvae which expand their mouth slowly, fluid entering the mouth cavity is expelled through the mouth before it is closed, resulting in flow reversal at the orifice. This relative efflux of water through the mouth was >8% of the influx through the mouth for younger ages. However similar effluxes were found when we simulated slow strikes by larger fish. The simulations can explain the observations of larval fish failing to fish due to the in-and-out movement of the prey. These results further highlight the importance of transporting the prey from the gape deeper into the mouth cavity in determining suction-feeding success.

Yuta Sakae, Akira Oikawa, Yuki Sugiura, Masatoshi Mita, Shuhei Nakamura, Toshiya Nishimura, Makoto Suematsu, and Minoru Tanaka

The teleost fish, medaka (Oryzias latipes), employs the XX/XY genetic sex determination system. We show here that the phenotypic sex of medaka is affected by changes in lipid metabolism. Medaka larvae subjected to 5 days of starvation underwent female-to-male sex reversal. Metabolomic and RT-qPCR analyses indicated that pantothenate metabolism was suppressed by starvation. Consistently, inhibiting the pantothenate metabolic pathway caused sex reversal. The final metabolite in this pathway is coenzyme A, an essential factor for lipogenesis. Inhibiting fatty acid synthesis, the first step of lipogenesis, also caused sex reversal. The expression of dmrt1, a critical gene for male development, was suppressed by starvation, and a dmrt1 (13) mutant did not show sex reversal under starvation. Collectively, these results indicate that fatty acid synthesis is involved in female-to-male sex reversal through ectopic expression of male gene dmrt1 under starvation.

A new study y reveals surprising findings about the function of circadian network neurons that undergo daily structural change. The research could lead to a better understanding of how to address circadian rhythm disruptions in humans and facilitate preventing a host of associated health problems, including increased risk for cancer and metabolic syndrome.

Alexion agrees deal for Portola to gain access to its lead product, Andexxa, a treatment that counteracts anticoagulants.

American markets, once a model of competition for the world, have experienced a growing concentration of economic power in a few large corporations. The rise of corporate economic—and political—power has emerged as one of the most important issues of our time. It is destined to be a key point of debate in the coming U.S.…