Watch: BBC China correspondent ordered to stop filming and pushed at car attack scene

Women announcers were often found as 'Shopping Reporters' on the 'women's hour' programs...

[The New Humanitarian] Malakal, South Sudan -- 'There is no house, no food, and no place to sleep for the children.'

TAIPEI: A state-funded English-language broadcaster in Taiwan removed a video of one of its journalists calling US President-elect Donald Trump a “convicted felon”, after the Taipei government said the incident was “very serious”.

Taiwan has publicly congratulated Trump on his victory, joining other governments around the world in trying to get onside with the next US administration.

Washington has long been Taipei’s most important supporter, but Trump raised concerns on the campaign trail by suggesting Taiwan should pay the United States for its defence and accusing it of stealing the US semiconductor industry.

TaiwanPlus correspondent Louise Watt was speaking on camera in the United States last week when she said “the US is either going to vote in its first female president or its first convicted felon”.

“Well America looks like it’s chosen the felon,“ Watt said, in a clip shared by Taiwanese broadcaster TVBS and seen by AFP.

Taiwan Culture Minister Li Yuan told local media on Saturday that TaiwanPlus took down the video after he told the broadcaster “that this issue is very serious”.

Public Television Service Foundation, which manages TaiwanPlus, said Monday the broadcaster had “humbly reviewed its operational procedures” following the report.

The foundation said it will convene a “self-discipline” committee this week to “discuss the matter”.

TaiwanPlus broadcasts videos on its website, YouTube and cable television.

More than 90 percent of its viewers are overseas, the foundation said.

In 2023, TaiwanPlus began showing in US hotels in “key cities frequented by political and economic elites, such as Washington, D.C., New York, Los Angeles, and Seattle”, the foundation said.

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Wednesday, December 11 at 11:00 am CT Remain in compliance with both Section 1071 and the Home Mortgage Disclosure Act with an efficient application process. While financial institutions are correctly concerned about how Section 1071 implementation will impact their processes, don’t miss this HMDA refresher to help prepare for the March 1st reporting deadline. As...

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In response to the release of Evan Gershkovich, a journalist wrongfully imprisoned in Russia since March 2023, the following statement can be attributed to NAB President and CEO Curtis LeGeyt.

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It's not just the pros who want control. Over the weekend the NCAA ejected a Louisville Courier-Journal reporter from a college baseball championship for live-blogging the game. Brian Bennet reports that he had been posting updates throughout the game on his Courier-Journal blog, until, at the bottom of the fifth inning, "an NCAA representative came to my seat on press row and asked for my credential and asked me to leave. I complied."

Apparently, according to a memo NCAA circulated, the college athletic association believes that live-blogging interferes with its revenue streams from broadcast licenses:

The College World Series Media Coordination staff along with the NCAA Broadcasting group needs to remind all media coordinators that any statistical or other live representation of the Super Regional games falls under the exclusive broadcasting and Internet rights granted to the NCAA's official rights holders and therefore is not allowed by any other entity. Since blogs are considered a live representation of the game, any blog that has action photos or game reports, including play-by-play, scores or any in-game updates, is specifically prohibited. In essence, no blog entries are permitted between the first pitch and the final out of each game.

Now there are legal and policy questions here: First off, this wasn't a copyright or misappropriation claim. If the reporter had watched or listened to a broadcast and blogged details from there, the NCAA would have no claim against him (see NBA v. Motorola, where the basketball association lost just such a claim). It can't claim ownership of the facts, even if it currently makes money from selling privileged access to the facts.

Instead, the NCAA was clamping down on the data through a claimed right to control physical access to the game, at least to the press box. Was the NCAA within its legal rights to revoke a press credential? Probably. The NCAA has no obligation to issue press credentials, and apart from anti-discrimination law, can condition them on whatever arbitrary terms it likes. But David Price points out another twist: The University of Louisville, where the game was played, is a public institution, subject to First Amendment limitations on the speech-limiting rules it can impose. Can it ban speech or allow others to do so on its space based on claimed disruption to a business deal? Does it depend whether a baseball stadium is a "public forum"? (Under current law, it's probably not.)

Finally, there's the policy. Even if banning bloggers is legally permissible, it;s silly. Silly of the NCAA to think it can keep up this kind of control, silly of licensees to see blogs as a substitute to what they're licensing, and silly of schools to endorse and accept such policies for their student athletes' games. Exclusivity of facts is unlikely to last long in practice, as the Courier-Journal reports: "The Oregonian newspaper in Portland decided to work around the rules by blogging Oregon State's game against Michigan on Sunday off a radio broadcast in its newsroom, said its executive editor, Peter Bhatia. He said the newspaper heard no objections from the NCAA and planned to do the same yesterday."

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TNF is a highly pro-inflammatory cytokine that contributes not only to the regulation of immune responses but also to the development of severe inflammatory diseases. TNF is synthesized as a transmembrane protein, which is further matured via proteolytic cleavage by metalloproteases such as ADAM17, a process known as shedding. At present, TNF is mainly detected by measuring the precursor or the mature cytokine of bulk cell populations by techniques such as ELISA or immunoblotting. However, these methods do not provide information on the exact timing and extent of TNF cleavage at single-cell resolution and they do not allow the live visualization of shedding events. Here, we generated C-tag TNF as a genetically encoded reporter to study TNF shedding at the single-cell level. The functionality of the C-tag TNF reporter is based on the exposure of a cryptic epitope on the C terminus of the transmembrane portion of pro-TNF on cleavage. In both denatured and nondenatured samples, this epitope can be detected by a nanobody in a highly sensitive and specific manner only upon TNF shedding. As such, C-tag TNF can successfully be used for the detection of TNF cleavage in flow cytometry and live-cell imaging applications. We furthermore demonstrate its applicability in a forward genetic screen geared toward the identification of genetic regulators of TNF maturation. In summary, the C-tag TNF reporter can be employed to gain novel insights into the complex regulation of ADAM-dependent TNF shedding.

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A state-funded English-language broadcaster in Taiwan removed a video of one of its journalists calling US President-elect Donald Trump a "convicted felon", after the Taipei government said the incident was "very serious".

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Massively parallel reporter assays (MPRAs) are powerful tools for quantifying the impacts of sequence variation on gene expression. Reading out molecular phenotypes with sequencing enables interrogating the impact of sequence variation beyond genome scale. Machine learning models integrate and codify information learned from MPRAs and enable generalization by predicting sequences outside the training data set. Models can provide a quantitative understanding of cis-regulatory codes controlling gene expression, enable variant stratification, and guide the design of synthetic regulatory elements for applications from synthetic biology to mRNA and gene therapy. This review focuses on cis-regulatory MPRAs, particularly those that interrogate cotranscriptional and post-transcriptional processes: alternative splicing, cleavage and polyadenylation, translation, and mRNA decay.

Internal ribosomal entry sites (IRESs) recruit the ribosome to promote translation, typically in an m7G cap-independent manner. Although IRESs are well-documented in viral genomes, they have also been reported in mammalian transcriptomes, where they have been proposed to mediate cap-independent translation of mRNAs. However, subsequent studies have challenged the idea of these "cellular" IRESs. Current methods for screening and discovering IRES activity rely on a bicistronic reporter assay, which is prone to producing false positive signals if the putative IRES sequence has a cryptic promoter or cryptic splicing sites. Here, we report an assay for screening IRES activity using a genetically encoded circular RNA comprising a split nanoluciferase (nLuc) reporter. The circular split nLuc reporter is less susceptible to the various sources of false positives that adversely affect the bicistronic IRES reporter assay and provides a streamlined method for screening IRES activity. Using the circular split nLuc reporter, we find that nine reported cellular IRESs have minimal IRES activity. Overall, the circular split nLuc reporter offers a simplified approach for identifying and validating IRESs and exhibits reduced propensity for producing the types of false positives that can occur with the bicistronic reporter assay.

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