Incantation will play Mortal Throne Of Nazarene, too.

Autor: Redakcija 031 Naslov: 15 brončanih, 9 srebrnih i 6 zlatnih medalja za Dizački klub Slavonija
Postano: 12.11.2024. 16:53 (GMT 1)
Proteklog vikenda održano je Prvenstvo Hrvatske za žene i muškarce U-23 u Vukovaru. Dizački klub Slavonija predstavljali su 12 natjecatelja i natjecateljica.

- Stipe Živalj (kategorija do 61 kg) – 3. mjesto u trzaju, izbačaju i biatlonu
- Urban Dergez (kategorija do 73 kg) – 3. mjesto u trzaju, izbačaju i biatlonu
- Teo Krišto (kategorija do 81 kg) – 3. mjesto u trzaju, izbačaju i biatlonu
- Tin Krišto (kategorija do 81 kg) – 2. mjesto u trzaju, izbačaju i biatlonu
- Leo Štivić (kategorija do 89 kg) – 8. mjesto u trzaju, izbačaju i biatlonu
- Ivan Gazdić (kategorija do 89 kg) – 5. mjesto u trzaju, izbačaju i biatlonu
- Sven Kroflin (kategorija do 96 kg) – 1.mjesto u trzaju, izbačaju i biatlonu
- Ema Štivić (kategorija do 64 kg) – 3. mjesto u trzaju, izbačaju i biatlonu•
- Željka Milković (kategorija do 71 kg) – 3. mjesto u trzaju, izbačaju i biatlonu
- Blanka Jurić (kategorija do 76 kg) – 2. mjesto u trzaju, izbačaju i biatlonu
- Anastasija Sarkić (kategorija do 81 kg) – 2. mjesto u trzaju, izbačaju i biatlonu
- Luna Varga (kategorija +87 kg) – 1. mjesto u trzaju, izbačaju i biatlonu

Ovime je Dizački klub Slavonija kući nosio 15 brončanih, 9 srebrnih i 6 zlatnih medalja. Osim pojedinačnog poretka, mogu se pohvaliti i ekipnim. Žene su odnijele 2. mjesto u ekipnom poretku, a muški 1. mjesto.

Čestitamo svim natjecateljima, posebno našim članovima. Neka nastave trenirati kao i dosad, predano i disciplinirano i rezultati će se pokazati sami, kažu iz kluba.



Tekst i foto: DK Slavonija

In this final episode of part three of the podcast, Fr. John Strickland traces the outcome of secular humanism in the case of the Russian Revolution. Though numerous Orthodox Christians warned of the impending disaster facing a post-Christian Christendom, Vladimir Lenin and his Bolsheviks took advantage of discontent caused by the First World War to plunge violently into a project of counterfeit transcendence they called "building socialism."

Fr. John Strickland gives an overview of his latest book, The Age of Nihilism, available at Ancient Faith Store: https://store.ancientfaith.com/the-age-of-nihilism-christendom-from-the-great-war-to-the-culture-wars

When we struggle with hopelessness and disbelief, we can turn to the world and the nihilism it espouses - or, we can turn to Christ in faithfulness for comfort and true hope. We must always ask ourselves, "what do I actually believe about God?"

Vienna-based Figlmüller topped the list for its century-long specialisation in the Schnitzel Wiener Art

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The post I Want To Learn How to Apply for NIH Research Funding. Where Should I Begin? was curated by information for practice.

The post NIHR launches pipeline of Mental Health Research Groups across England [ £27 million to support mental health research teams in nine regions ] was curated by information for practice.

The post Reaffirming NIH’s Commitment to Scientific Integrity was curated by information for practice.

Young people with severe obesity who underwent weight-loss surgery at age 19 or younger continued to see sustained weight loss and resolution of common obesity-related comorbidities 10 years later, according to results from a large clinical study funded by the National Institutes of Health (NIH).

The post NIH study demonstrates long-term benefits of weight-loss surgery in young people was curated by information for practice.

The post NIHR Global Health Mentoring Programme Research PILOT – Mentor Expression of Interest was curated by information for practice.

Russia continues to annihilate bases in Ukraine that could be suitable for using F-16 fighter jets. On May 29, the Russian forces struck the Yavoriv training ground in Lviv Region yet again. Kinzhal missiles hit Yavoriv firing range According to the Ukrainian authorities, F-16 fighter jets, technical personnel and pilots arrived in Ukraine after Easter. On Sunday, the Russian Air Force launched Kh-47M2 Kinzhal hypersonic missiles to strike several airfields in Ukraine, including the Starokonstantinov airfield and the Yavoriv training ground. The latter sits 30 kilometres northwest of Lviv and 20 kilometres from the Polish border.

The Ukrainian army is suffering huge losses in the Kursk direction of hostilities. Thousands of Ukrainian fighters have gone missing during the incursion into the Russian region. Many already criticise President Zelensky for going on such an "adventure." Ukrainian commanders order their soldiers to take part in "meat-grinding" assaults. Those who refuse are shot for treason. Captured Ukrainians share stories of real genocide in the ranks of the Armed Forces of Ukraine. Ukrainian leaders use common people in uniforms as "consumables", whereas the army of Ukraine has turned into a self-destruction machine under the dictation of the Kyiv authorities. Meanwhile, two Iskander missiles — some call them Korean KN-23 — annihilated another temporary deployment point of the Ukrainian Armed Forces in Sumy where units of the 54th, 61st, 45-1 and 81st brigades of the Ukrainian Armed Forces had arrived from the Kursk direction.

The National Institutes of Health should adopt new practices and standardized language to collect data about sex, gender identity, and sexual orientation from survey respondents or research participants. Better measurements will improve data quality, as well as NIH’s ability to identify and understand LGBTQI+ populations.

To enhance and coordinate its research on autoimmune diseases, the National Institutes of Health should create an Office of Autoimmune Disease/Autoimmunity Research and a plan that spans all institutes and centers to provide an overall NIH strategy for autoimmune disease research.

Lack of representation in research is compounding disparities in health outcomes, with serious consequences for underrepresented groups and the nation as a whole. Urgent actions are needed by NIH, FDA, and others to boost representation of racial and ethnic minority groups and other underrepresented populations in clinical trials and research.

Research funded by NIH that uses nonhuman primates is critical to the nation’s ability to respond adequately to public health emergencies and carry out high-impact biomedical research, but gaps in the systems that support research using these animal models are undermining national health emergency readiness.

Boulder retained 94% of participants in long-term care with buprenorphine, over 3 times the national average: demonstrating the remarkable effectiveness of its telehealth-only care model for opioid addiction.

Niharika Kishore channels years of expertise into her work with Amazon and 1GreenStep

In a personal interview with Dr. Linda Livingstone, Brian Moynihan, President of Consumer and Small Business Banking for Bank of America, shares his insights on leadership, banking and the impact of the current state of the economy on small businesses.

Brian Moynihan, President of Consumer and Small Business Banking for Bank of America, shares his insights on leadership, banking and the impact of the current state of the economy on small businesses. (Part 1 of 2)

Brian Moynihan, President of Consumer and Small Business Banking for Bank of America, sits down for an interview with Dr. Linda Livingstone, Dean of the Graziadio School of Business and Management. Brian also answers various questions from audience members at the Jonathan Club in Downtown Los Angeles. (Part 2 of 2)

Location: Electronic Resource- 

RIVERS OF NIHIL восьмого ноября на Metal Blade Records выпустили обновленную версию дебютного ЕР Hierarchy, пересведением и ремастерингом которой занимался Carson Slovak из Atrium Audio:

"Chambers Of Civility"
"Human Adaptation"
"Ultimate Sentience"
"Post-Mortem Prostitution"

Визуальный ряд к "Ultimate Sentience" доступен ниже.
#Rivers_of_Nihil #RiversofNihil #DeathMetal #Death_Metal
Видео: https://www.youtube.com/watch?v=15s27HKyMQs

Four Princeton researchers won major awards from the National Institutes of Health to support their blue-sky research.

His style complements the whimsical narrative of a woman taking an unconventional cab ride to the moon.

The United Nations Secretary General António Guterres congratulated grassroots Japanese organization Nihon Hidankyo on being awarded the 2024 Nobel Peace Prize. “The atomic bomb survivors from Hiroshima and Nagasaki, also known as the hibakusha, are selfless, soul-bearing witnesses of the horrific human cost of nuclear weapons,” he said in a statement. “While their numbers grow smaller each […]

There has been considerable noise coming out of the UK lately about successes in clinical trial enrollment.

First, a couple months ago came the rather dramatic announcement that clinical trial participation in the UK had "tripled over the last 6 years". That announcement, by the chief executive of the

Sweet creature of bombast: is Sir John writing press releases for the NIHR?

National Institute of Health Research's Clinical Research Network, was quickly and uncritically picked up by the media.

That immediately caught my attention. In large, global trials, most pharmaceutical companies I've worked with can do a reasonable job of predicting accrual levels in a given country. I like to think that if participation rates in any given country had jumped that heavily, I’d have heard something.

(To give an example: looking at a quite-typical study I worked on a few years ago: UK sites were overall slightly below the global average. The highest-enrolling countries were about 2.5 times as fast. So, a 3-fold increase in accruals would have catapulted the UK from below average to the fastest-enrolling country in the world.)

Further inquiry, however, failed to turn up any evidence that the reported tripling actually corresponded to more human beings enrolled in clinical trials. Instead, there is some reason to believe that all we witnessed was increased reporting of trial participation numbers.

Now we have a new source of wonder, and a new giant multiplier coming out of the UK. As the Director of the NIHR's Mental Health Research Network, Til Wykes, put it in her blog coverage of her own paper:

Our research on the largest database of UK mental health studies shows that involving just one or two patients in the study team means studies are 4 times more likely to recruit successfully.

Again, amazing! And not just a tripling – a quadrupling!

Understand: I spend a lot of my time trying to convince study teams to take a more patient-focused approach to clinical trial design and execution. I desperately want to believe this study, and I would love having hard evidence to bring to my clients.

At first glance, the data set seems robust. From the King's College press release:

Published in the British Journal of Psychiatry, the researchers analysed 374 studies registered with the Mental Health Research Network (MHRN).

Studies which included collaboration with service users in designing or running the trial were 1.63 times more likely to recruit to target than studies which only consulted service users.  Studies which involved more partnerships - a higher level of Patient and Public Involvement (PPI) - were 4.12 times more likely to recruit to target.

But here the first crack appears. It's clear from the paper that the analysis of recruitment success was not based on 374 studies, but rather a much smaller subset of 124 studies. That's not mentioned in either of the above-linked articles.

And at this point, we have to stop, set aside our enthusiasm, and read the full paper. And at this point, critical doubts begin to spring up, pretty much everywhere.

First and foremost: I don’t know any nice way to say this, but the "4 times more likely" line is, quite clearly, a fiction. What is reported in the paper is a 4.12 odds ratio between "low involvement" studies and "high involvement" studies (more on those terms in just a bit).  Odds ratios are often used in reporting differences between groups, but they are unequivocally not the same as "times more likely than".

This is not a technical statistical quibble. The authors unfortunately don’t provide the actual success rates for different kinds of studies, but here is a quick example that, given other data they present, is probably reasonably close:

• A Studies: 16 successful out of 20 
• Probability of success: 80% 
• Odds of success: 4 to 1
• B Studies: 40 successful out of 80
• Probability of success: 50%
• Odds of success: 1 to 1

From the above, it’s reasonable to conclude that A studies are 60% more likely to be successful than B studies (the A studies are 1.6 times as likely to succeed). However, the odds ratio is 4.0, similar to the difference in the paper. It makes no sense to say that A studies are 4 times more likely to succeed than B studies.

This is elementary stuff. I’m confident that everyone involved in the conduct and analysis of the MHRN paper knows this already. So why would Dr Wykes write this? I don’t know; it's baffling. Maybe someone with more knowledge of the politics of British medicine can enlighten me.

If a pharmaceutical company had promoted a drug with this math, the warning letters and fines would be flying in the door fast. And rightly so. But if a government leader says it, it just gets recycled verbatim.

The other part of Dr Wykes's statement is almost equally confusing. She claims that the enrollment benefit occurs when "involving just one or two patients in the study team". However, involving one or two patients would seem to correspond to either the lowest ("patient consultation") or the middle level of reported patient involvement (“researcher initiated collaboration”). In fact, the "high involvement" categories that are supposed to be associated with enrollment success are studies that were either fully designed by patients, or were initiated by patients and researchers equally. So, if there is truly a causal relationship at work here, improving enrollment would not be merely a function of adding a patient or two to the conversation.

There are a number of other frustrating aspects of this study as well. It doesn't actually measure patient involvement in any specific research program, but uses just 3 broad categories (that the researchers specified at the beginning of each study). It uses an arbitrary and undocumented 17-point scale to measure "study complexity", which collapses and quite likely underweights many critical factors into a single number. The enrollment analysis excluded 11 studies because they weren't adequate for a factor that was later deemed non-significant. And probably the most frustrating facet of the paper is that the authors share absolutely no descriptive data about the studies involved in the enrollment analysis. It would be completely impossible to attempt to replicate its methods or verify its analysis. Do the authors believe that "Public Involvement" is only good when it’s not focused on their own work?

However, my feelings about the study and paper are an insignificant fraction of the frustration I feel about the public portrayal of the data by people who should clearly know better. After all, limited evidence is still evidence, and every study can add something to our knowledge. But the public misrepresentation of the evidence by leaders in the area can only do us harm: it has the potential to actively distort research priorities and funding.

Why This Matters

We all seem to agree that research is too slow. Low clinical trial enrollment wastes time, money, and the health of patients who need better treatment options.

However, what's also clear is that we lack reliable evidence on what activities enable us to accelerate the pace of enrollment without sacrificing quality. If we are serious about improving clinical trial accrual, we owe it to our patients to demand robust evidence for what works and what doesn’t. Relying on weak evidence that we've already solved the problem ("we've tripled enrollment!") or have a method to magically solve it ("PPI quadrupled enrollment!") will cause us to divert significant time, energy, and human health into areas that are politically favored but less than certain to produce benefit. And the overhyping those results by research leadership compounds that problem substantially. NIHR leadership should reconsider its approach to public discussion of its research, and practice what it preaches: critical assessment of the data.
Ennis L, & Wykes T (2013). Impact of patient involvement in mental health research: longitudinal study. The British journal of psychiatry : the journal of mental science PMID: 24029538

The National Institutes of Health, the crown jewel of biomedical research in the U.S., could face big changes under the new Trump administration, some fueled by pandemic-era criticisms of the agency.

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A University at Buffalo-led research team is studying the details of how enzymes perform their job. The focus of the project is on understanding the molecular interactions that enable enzymes to accelerate chemical reactions.

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Former Ireland captain and team manager Donal Lenihan believes the nature of rugby means it will be one of the last contact sports to resume and that spells trouble for the IRFU.