modelling

A Hierarchical Surrogate Approach to Biomass Ethanolysis Reaction Kinetic Modelling

React. Chem. Eng., 2024, Accepted Manuscript
DOI: 10.1039/D4RE00378K, Paper
Ailís O'Shea, Conall McNamara, Prajwal Rao, Mícheál Séamus Howard, Mohammad Reza Ghaani, Stephen Dooley
The reaction mechanism and kinetics of the sulfuric acid catalysed ethanolysis of glucose, cellulose, xylan, and corncob was investigated using a combination of experiments and empirical reaction mechanism modelling. The...
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modelling

Tectonic-paleogeographic implications of a detailed Cretaceous-Cenozoic exhumation history in the Richardson Anticlinorium, northern Yukon, documented by multi-kinetic apatite fission track modelling

Lane, L S; Issler, D R; O'Sullivan, P B. Geoconvention 2020 abstracts; 2020 p. 1-2
<a href="https://geoscan.nrcan.gc.ca/images/geoscan/20210002.jpg"><img src="https://geoscan.nrcan.gc.ca/images/geoscan/20210002.jpg" title="Geoconvention 2020 abstracts; 2020 p. 1-2" height="150" border="1" /></a>




modelling

A multikinetic approach to apatite fission-track thermal modelling using elemental data: data and model results for a Permian and Devonian sample from northern Yukon

Issler, D R; McDannell, K T; Lane, L S; O'Sullivan, P B; Neill, O K. Geological Survey of Canada, Open File 8821, 2021, 158 pages, https://doi.org/10.4095/328844
<a href="https://geoscan.nrcan.gc.ca/images/geoscan/gid_328844.jpg"><img src="https://geoscan.nrcan.gc.ca/images/geoscan/gid_328844.jpg" title="Geological Survey of Canada, Open File 8821, 2021, 158 pages, https://doi.org/10.4095/328844" height="150" border="1" /></a>




modelling

Simulating sedimentary burial cycles: II. Elemental-based multikinetic apatite fission-track interpretation and modelling techniques illustrated using examples from northern Yukon

Issler, D R; McDannell, K T; O'Sullivan, P B; Lane, L S. Geochronology vol. 4, 2022 p. 373-397, https://doi.org/10.5194/gchron-4-373-2022
<a href="https://geoscan.nrcan.gc.ca/images/geoscan/20210455.jpg"><img src="https://geoscan.nrcan.gc.ca/images/geoscan/20210455.jpg" title="Geochronology vol. 4, 2022 p. 373-397, https://doi.org/10.5194/gchron-4-373-2022" height="150" border="1" /></a>




modelling

Amanda Holden's daughter joins Kate Moss' modelling agency




modelling

Advancing Creative Visual Thinking with Constructive Function-based Modelling




modelling

Double-Buffer Traffic Shaper Modelling for Multimedia Applications in Slow Speed Network




modelling

User Acceptance of the E-Government Services in Malaysia: Structural Equation Modelling Approach




modelling

Modelling End Users’ Continuance Intention to Use Information Systems in Academic Settings: Expectation-Confirmation and Stress Perspective

Aim/Purpose: The main aim of this study is to identify the factors that influence the continuance intention of use of innovative systems by non-academic employees of a private university and associated academic institutions in Bangladesh. Background: The targeted academic institutions have introduced many new online services aimed at improving students’ access to information and services, including a new online library, ERP or online forum, and the jobs-tracking system (JTS). This research is focused only on the JTS for two reasons. First, it is one of the most crucial systems for the Daffodil Family, as it enables efficient working across many institutes spread across the country and abroad. Second, it is employed in a wide variety of organisational institutes, not just the university. This study aims to discover negative factors that lead to a decrease in users’ intentions to continue using the system. The ultimate goal is to improve the motivation among administrative staff to use technology-related innovation by reducing or eliminating the problems. Methodology: G* power analysis was employed to determine the expected sample size. A questionnaire survey was conducted of 211 users of a new job tracking system from a private university in Bangladesh, to collect data for testing the suggested research model. The data was analysed using the structural equation technique, which is a powerful multivariate analysis mechanism. Contribution: This research contributes to the body of literature and helps better understand users’ continuance intention in the post-implementation phase of the JTS. It complements the micro-level examinations of continuance intention of using IT, by building on our understanding of the phenomenon at the individual level. Specifically, this study examines the role of technostress where organisations invest in IT to make their users more comfortable with innovative and new technologies like the JTS. Findings: This research develops a theoretical advancement of the expectation-confirmation theory, with implications for IT managers and senior management dealing with IT-related behaviour. All proposed hypotheses were supported. Specifically, the predictors of exhaustion – work overload, work–life balance, and role ambiguity – are significant. The core factors for satisfaction, perceived usefulness, and confirmation, are also found to be significant. Finally, satisfaction and exhaustion significantly influence continuance intention, in both positive and negative ways. Recommendations for Practitioners: This study gives an idea about some of the difficulties that people face when implementing new and innovative IT, particularly in academia in Bangladesh. It offers insights into strategies the management may want to follow when implementing new technology like the JTS. This study suggests strategies to increase satisfaction and reduce technostress among new users to enhance organisational support for change. Recommendation for Researchers: Methodologically, the study provides researchers about the technique that reduces the threat of the common method bias. First, it created a psychological separation between criterion and predictor variables. Second, the threat of common method variance was actively controlled by modelling a latent method factor and by using marker variables that researchers can use in their work. This study complements the micro-level examinations of continuance intention of using IT by building on our understanding of the phenomenon at the individual level. Researchers can extend this model by integrating other theories. Impact on Society: The findings of the study indicate that work overload, work–life conflict, and role ambiguity create tiredness, leading to lower user satisfaction with the system. Perceived usefulness and confirmation have an increasingly similar effect on users’ satisfaction with the system and their subsequent continuance intention. These findings tell university administrators what measures they should take to improve continuance intention of using innovative technology. Future Research: Future studies could conceptualise a five-factor personality model from the personal perspective of users. This model can also be extended by including the dimensions of absorptive capacity, i.e., the dynamic capabilities of users. Absorptive capacity of understanding, assimilating, and applying might influence the user’s perception of usefulness and confirmation of using JTS.




modelling

Job Alert: PostDoc position on modelling land biosphere dynamics

The Mediterranean Institute for Biodiversity and Ecology (IMBE, Aix-Marseille University, Aix-en-Provence, France), in its research group "Macroecology and Biogeography of Global Change (MacroBio)" has a PostDoc position open for applications. The post has a duration of 36 months, the initial contract is made for 18 months, being extended based on an assessment of performance. The position is funded by the European Commission through the FP7 Research Project LUC4C and affiliated to the French National Scientific Research Centre (CNRS).

The main topic is to improve the way LULCC processes are represented in the DGVM LPJmL through enhanced soil and vegetation process representation. Work should improve the model's capacity to project climate-LULCC interactions for the computation of net climate effects, and ecosystem services. One focus is on the representation of diverse agricultural management systems, cropland abandonment/afforestation and forest management, in order to develop ways to account for their effects on biochemical cycles and biophysics.

The PostDoc will also contribute to the actual assessment of indirect effects and trade-offs of LULCC. The team will look into the indirect effects of land-based mitigation options for climate change, and the interplay with climate change, across and within regions.

The successful candidate will have completed a doctorate in one of the environmental sciences. Substantial earth system modelling and programming skills are required, familiarity with highly modular C-code. Experience with Dynamic Global Vegetation Models will be a great advantage. The working language is English.

Interviews with successful candidates will begin after December 1, 2014. The position will be filled when a suitable candidate has been identified. To apply for this position, please send a letter of application, demonstrating your ability to understand the task, and your CV as soon as possible, but before the 31st of January 2015, by e-mail to Ms. Gabriela Boéri (Gabriela.Boeri@imbe.fr). For any questions about the task, working conditions, or the LUC4C project, please contact Dr Alberte Bondeau (alberte.bondeau@imbe.fr).

 





modelling

Postdoctoral position: Modelling of the land-sea nutrient transfer to the Mediterranean sea under different land management scenarios

Post-doctoral scientist position is open for the project "Towards an integrated prediction of Land & Sea Responses to global change in the Mediterranean Basin" (LaSeR-Med), which focusses on integrated socio-ecological modelling. The duration of the contract is initially one year, with a possible extension for a second year, depending on the initial results. The post-doc will be based within the Mediterranean Institute of marine and terrestrial Biodiversity and Ecology (IMBE) in Aix-en-Provence, France. The project is part of the Labex OT-Med (http://www.otmed.fr/).

Applicants should hold a doctoral degree in physics, chemistry, microbiology, geosciences, environmental sciences or a related field of science. They should be familiar with modelling biogeochemical interactions between ecosystems and capable to further develop existing numerical ecosystem models. Programming skills (C) and modelling experience are therefore mandatory. Knowledge of R and of Unix/Linux environment will be an advantage. The candidate should have good written and oral communication skills. For work, good skills in the English language will be essential.

The project:

Terrestrial and marine ecosystems are connected through groundwater, river discharge and nutrient outflows (especially N and P). River catchments in the Mediterranean are N-intensive regions, mostly due to intensive agriculture in the North and to crop N2 fixation or food & feed import in the South. The fraction of nutrient reaching the sea constitutes significant anthropogenic forcing of many marine biological processes. For simulating the dynamics of the first levels of the marine food web (from nutrients to jellyfishes), the ocean biogeochemical model, Eco3M-MED, used and developed by the Mediterranean Institute of Oceanography (MIO) within OT-Med, currently uses N and P measurements at river mouths, e.g. for the Rhône.

In order to estimate the impacts of global change on the functioning of marine ecosystems, the project aims at modeling the dependency of N and P outflows to the Mediterreanean sea toward land management. Land management is modelled as part of the agro-ecosystem model LPJmL (Bondeau et al., 2007), that has been especially adapted to the Mediterranean cropping systems (Fader et al., 2015). Among others, LPJmL simulates the daily carbon and water cycles, and the river discharges to the sea. Following existing approaches in the scientific literature, the post-doc will implement the nutrient N and P transfer in LPJmL, covering the net nutrient inputs to the river catchments by accounting for the processes occurring at the agro-ecosystem level (N2 biological fixation, fertilization, atmospheric deposition) and the net food and feed imports. Since only a minor fraction of the net nutrient inputs from Mediterranean basins reaches the sea, the retention along the nutrient cascade will have to be added to the LPJmL river routing scheme, similarly to the method used by the Riverstrahler model. Once the nutrient transfers have been introduced into LPJmL, simulations will be validated using current climate and land use forcing for comparisons with the existing observations from river outlets. Finally, future conditions will be assessed by using the model with scenarios of changing regional climate and land use / land management.

Your application:

Applications should contain a suitable motivation letter describing your anticipated role in the project, a CV, a list of scientific publications and the names of at least two scientists that can be contacted for references. They must be sent to Ms. Gabriela Boéri (gabriela.boeri@imbe.fr). Please prepare your application as a single file in pdf-format.

Questions about the project or the position can be directed to Dr. Alberte Bondeau (alberte.bondeau@imbe.fr). The position will be filled as soon as a suitable candidate has been found – work should start soon after that date. The salary and contract conditions will be determined according to standards set by Aix-Marseille University – questions in this regard can be directed to Sophie Pekar (pekar@otmed.fr).





modelling

Article Alert: A virtual species set for robust and reproducible species distribution modelling tests

A new EU BON acknowledging data article provides a virtual species set as a valuable tool in biodiversity monitoring. 

Abstract

Predicting species potential and future distribution has become a relevant tool in biodiversity monitoring and conservation. In this data article we present the suitability map of a virtual species generated based on two bioclimatic variables, and a dataset containing more than 700,000 random observations at the extent of Europe. The dataset includes spatial attributes such as: distance to roads, protected areas, country codes, and the habitat suitability of two spatially clustered species (grassland and forest species) and a wide-spread species.

Original Source:

Garzon-Lopez, C.X., Bastin, L., Foody, G.M., Rocchini, D. (2016). A virtual species set for robust and reproducible Species Distribution Modelling tests. Data in Brief, 7: 476-479. doi: http://dx.doi.org/10.1016/j.dib.2016.02.058





modelling

Article Alert: Fostering integration between biodiversity monitoring and modelling

A new editorial, published in the Journal of Apllied Ecology looks at modelling and monitoring as methods for adaptive biodiversity management in the 21st century.

Abstract: 

With increasing threats on biodiversity, informed conservation decisions need to be based on currently observed and future predicted trends of biodiversity (Pereira, Navarro & Martins 2012; Guisan et al. 2013). In this regard, two essential components supporting informed biodiversity conservation decisions are good monitoring data to assess recent and ongoing trends (Collen et al. 2013; Pereira et al. 2013) and robust models to anticipate possible future trends (Pereira et al. 2010a; Akcakaya et al. 2016). Models benefit from robust monitoring data sets, that is repeated observations of biodiversity, as they need data to be fitted or validated, but models can also help assess data representativeness (e.g. by highlighting any bias), support proper data collection (e.g. covering the relevant gradients) or be used to make more effective use of biodiversity observations (Guisan et al. 2006, 2013; Ferrier 2011).

Read more in the open access paper.





modelling

Optimising long-term monitoring projects for species distribution modelling: how atlas data may help





modelling

D3.2 Report on integrated distributional modelling and associated software




modelling

A virtual species set for robust and reproducible Species Distribution Modelling tests





modelling

Fostering integration between biodiversity monitoring and modelling




modelling

Modelling geographic access and school catchment areas across public primary schools to support subnational planning in Kenya.

Children's Geographies; 10/01/2023
(AN 173035616); ISSN: 14733285
Academic Search Premier




modelling

A Loss Cycle of Burnout Symptoms and Reduced Coping Self-Efficacy: A Latent Change Score Modelling Approach

Chronic Stress, Volume 8, Issue , January-December 2024. Police officers are frequently faced with chronic and acute stressors, such as excessive workload, organizational stressors and emotionally charged reports. This study aims to examine the relationship between a form of chronic strain (ie, burnout symptoms) and a resource (ie, coping self-efficacy) in a sample of Dutch […]

The post A Loss Cycle of Burnout Symptoms and Reduced Coping Self-Efficacy: A Latent Change Score Modelling Approach was curated by information for practice.



  • Open Access Journal Articles

modelling

Staff Verification Engineer, CPU Modelling, Experienced Professionals, Bangalore, India, Software Engineering

Introduction

Arm architects the pervasive intelligence that is transforming our daily experience. Arm-based chips and device architectures orchestrate the performance of the technology that makes modern life possible.Arm designs the technology which is at the heart of advanced digital products, from wireless, networking and consumer entertainment solutions to imaging, automotive, security and storage devices. Arm improves people’s lives by enabling the intelligence in affordable, easy-to-use electronic products that transform the way we live and work. We work in partnership with a global network of leading technology companies which are using our smart low-power technology. Together we are shaping the future of a better world.

Today, We are well recognized as the market leader in the CPU and System IP industry and this has been achieved by consistently delivering reliable and high-quality IP products. The cost of design and manufacturing and that warrants “right first time” approach for all IP and System products by our partners. Time-to-market is critical for our partners to deal with fierce competition in the marketplace, being first would enable them to get premium value from the end products. In this context, Design Verification of CPU IPs is a big challenge requiring an engineering skillset that is both broad and deep.




modelling

2021 Graduate Modelling Engineer - Cambridge, Graduates, Cambridge, UK, Cambridge, UK, Software Engineering

We have an exciting opportunity for a graduate developer in the GPU modelling team, based in Cambridge. We work with software models which are state-of-the-art representations of our products. They are used by several teams within the company and are delivered externally to some of our partners.

We develop in C++ in a UNIX environment. Working in the GPU modelling team, your role will primarily be to model the functional and performance aspects of our GPUs. You will be working with dedicated and talented people across the globe as part of our multi-site development projects. Your work will have a large impact on the design and quality of our GPUs and ultimately on the success of Arm.

If you would like to shape the future of energy-efficient devices, this is the place to be!

 
 




modelling

Modelling dynamical 3D electron diffraction intensities. I. A scattering cluster algorithm

Three-dimensional electron diffraction (3D-ED) is a powerful technique for crystallographic characterization of nanometre-sized crystals that are too small for X-ray diffraction. For accurate crystal structure refinement, however, it is important that the Bragg diffracted intensities are treated dynamically. Bloch wave simulations are often used in 3D-ED, but can be computationally expensive for large unit cell crystals due to the large number of diffracted beams. Proposed here is an alternative method, the `scattering cluster algorithm' (SCA), that replaces the eigen-decomposition operation in Bloch waves with a simpler matrix multiplication. The underlying principle of SCA is that the intensity of a given Bragg reflection is largely determined by intensity transfer (i.e. `scattering') from a cluster of neighbouring diffracted beams. However, the penalty for using matrix multiplication is that the sample must be divided into a series of thin slices and the diffracted beams calculated iteratively, similar to the multislice approach. Therefore, SCA is more suitable for thin specimens. The accuracy and speed of SCA are demonstrated on tri-iso­propyl silane (TIPS) pentacene and rubrene, two exemplar organic materials with large unit cells.




modelling

Modelling dynamical 3D electron diffraction intensities. II. The role of inelastic scattering

The strong interaction of high-energy electrons with a crystal results in both dynamical elastic scattering and inelastic events, particularly phonon and plasmon excitation, which have relatively large cross sections. For accurate crystal structure refinement it is therefore important to uncover the impact of inelastic scattering on the Bragg beam intensities. Here a combined Bloch wave–Monte Carlo method is used to simulate phonon and plasmon scattering in crystals. The simulated thermal and plasmon diffuse scattering are consistent with experimental results. The simulations also confirm the empirical observation of a weaker unscattered beam intensity with increasing energy loss in the low-loss regime, while the Bragg-diffracted beam intensities do not change significantly. The beam intensities include the diffuse scattered background and have been normalized to adjust for the inelastic scattering cross section. It is speculated that the random azimuthal scattering angle during inelastic events transfers part of the unscattered beam intensity to the inner Bragg reflections. Inelastic scattering should not significantly influence crystal structure refinement, provided there are no artefacts from any background subtraction, since the relative intensity of the diffracted beams (which includes the diffuse scattering) remains approximately constant in the low energy loss regime.




modelling

Modelling the power threshold and optimum thermal deformation of indirectly liquid-nitro­gen cryo-cooled Si monochromators

Maximizing the performance of crystal monochromators is a key aspect in the design of beamline optics for diffraction-limited synchrotron sources. Temperature and deformation of cryo-cooled crystals, illuminated by high-power beams of X-rays, can be estimated with a purely analytical model. The analysis is based on the thermal properties of cryo-cooled silicon crystals and the cooling geometry. Deformation amplitudes can be obtained, quickly and reliably. In this article the concept of threshold power conditions is introduced and defined analytically. The contribution of parameters such as liquid-nitro­gen cooling efficiency, thermal contact conductance and interface contact area of the crystal with the cooling base is evaluated. The optimal crystal illumination and the base temperature are inferred, which help minimize the optics deformation. The model has been examined using finite-element analysis studies performed for several beamlines of the Diamond-II upgrade.




modelling

Canadian Blood Services research engineer applies network modelling techniques and mentorship skills to benefit Canada’s Lifeline

Canadian Blood Services research engineer applies network modelling techniques and mentorship skills to benefit Canada’s Lifeline


Tuesday, October 22, 2024 Dr. Emily Freeman

Dr. John Blake is a research engineer at Canadian Blood Services and a Professor in the Department of Industrial Engineering at Dalhousie University. Based in Halifax, Nova Scotia, Dr. Blake and his trainees use engineering principles and various computer-based optimization techniques to inform large scale decisions at Canadian Blood Services.  

Applying network modelling to biologics  

To some, it may be surprising to learn that there is such opportunity to integrate engineering into the health-care focused setting of Canadian Blood Services. However, as Dr. Blake explains, the same engineering principles that apply to the development and quality assurance of other products also apply to biologics such as blood, stem cells and organs. One of these classic engineering approaches currently applied to improving operations at Canadian Blood Services is network modelling.  

Network modelling is a computer-based method that creates a virtual representation of objects and their relation to each other. The resulting models are particularly useful for maintaining adaptability in the collection of blood donations, as well as the distribution and inventory management strategies that allow Canadian Blood Services to remain a safe and reliable provider of life-saving products. 

Dr. Blake making friends while walking the Camino de Santiago in Spain

Contributing to efficiency and sustainability in Canada’s Lifeline  

For Dr. Blake’s team, modelling is not about the data acquired but rather how they can turn existing data into real life change. Part of this approach is ensuring that Canadian Blood Services is asking the right questions when it comes to allocating resources. For example, Dr. Blake has worked on models to assess how changing stem cell donor recruitment will affect the number of matches for Canadian patients. By modelling things such as recruitment approaches, Dr. Blake’s work assists Canadian Blood Services to consistently identify ways to improve Canada’s Lifeline.

Recently, Dr. Blake has also been applying this method to optimize the number and location of mobile and permanent donor facilities across the nation. This redesign of the donation facility network will address the growing demand for donations by bringing Canadian Blood Services’ facilities closer to the donors. 

“I have waited my entire career for a problem of this type – it is truly a once in a lifetime opportunity.”

Dr. John Blake, Canadian Blood Services Research Engineer

Securing the future of Canada’s Lifeline  

To sustain a safe and effective blood system in Canada for years to come, network modelling and optimization is a never-ending process. This is one of the reasons that Dr. Blake is committed to securing the future of transfusion and transplantation systems by training and mentoring the next generation of engineers. In fact, seeing his former students join Canadian Blood Services and dedicate their talents to improving the future of Canada’s Lifeline is one of Dr. Blake’s proudest achievements.  

One of Dr. Blake’s former students, Matt Nelson, is now an industrial engineer at Canadian Blood Services.  

“In my role, I use systematic thinking to build and run complex models; collect and analyze the required data; produce useful results; and explain these results to non-technical leaders on a regular basis,” Matt says. Recently, Matt contributed to the launch and expansion of pathogen-reduced platelets, a new product that was implemented across Canadian Blood Services production sites starting in 2022. The implementation of pathogen-reduced platelets has provided an additional layer of safety for recipients by reducing the risk of potential transfusion-transmitted pathogens without compromising the quality of the component. Matt credited Dr. Blake in helping him develop the necessary skills he now dedicates to safeguarding Canada’s Lifeline:  

“Dr. Blake was the professor who introduced me to the uses of simulation to understand complex non-linear systems. This type of system is very common in situations that have a lot of variability – like the blood system – and simulation allows for exploration of the response of the system to changes.” 

Matt Nelson, Canadian Blood Services Industrial Engineer

Over the years, Dr. Blake’s ongoing modelling work and mentorship activities have also led to many recognitions and awards, but he is most proud of being recognized as Professor of the Year by Dalhousie Undergraduate students, and with awards for his contributions to the Canadian Operational Research Society. He has even the earned the distinction of being Dalhousie’s first engineer to be awarded grant funding from the tri-council agency, Social Sciences and Humanities Research Council (SSHRC). 

“I am proud to work on projects that have a measurable impact on people’s health and well-being,” Dr. Blake says. “I am forever grateful to Dr. Dana Devine for first giving me the opportunity to serve Canadians in this role at Canadian Blood Services.” 


Canadian Blood Services – Driving world-class innovation

Through discovery, development and applied research, Canadian Blood Services drives world-class innovation in blood transfusion, cellular therapy and transplantation—bringing clarity and insight to an increasingly complex healthcare future. Our dedicated research team and extended network of partners engage in exploratory and applied research to create new knowledge, inform and enhance best practices, contribute to the development of new services and technologies, and build capacity through training and collaboration. Find out more about our research impact.   

The opinions reflected in this post are those of the author and do not necessarily reflect the opinions of Canadian Blood Services nor do they reflect the views of Health Canada or any other funding agency.  

Related blog posts


Tuesday, March 29, 2022
Marie-Soleil Smith

This post was written by Marie-Soleil Smith, PhD Candidate in Dr. Hélène Côté’s Lab at the University of British Columbia, and edited by Dr. Geraldine Walsh, knowledge broker at Canadian Blood Services. It originally appeared on the Centre for Blood Research blog in March 2022.


Monday, January 22, 2018
Dr. Geraldine Walsh

For the latest instalment of “Meet the researcher” we chatted with Dr. John Blake, Canadian Blood Services’ research engineer and also known as “the numbers guy”.


Wednesday, June 13, 2018
Jenny Ryan

On June 5, Canadian Blood Services was honoured to accept the Canadian Operational Research Society's Omandt Solandt Award at a reception in Halifax, Nova Scotia. Michelle Rogerson, Director, Supply Chain (Atlantic), Canadian Blood Services, accepted the award on behalf of the organization. About...




modelling

[ K.Sup31 (10/22) ] - ITU-T K.118 - Requirements for lightning protection of fibre to the distribution point equipment - Modelling earth potential rise

ITU-T K.118 - Requirements for lightning protection of fibre to the distribution point equipment - Modelling earth potential rise




modelling

Modelling Human Behaviour in Landscapes Basic Concepts and Modelling Elements

Location: Electronic Resource- 




modelling

Modelling and precision control of systems with hysteresis

Location: Engineering Library- TJ223.A25L58 2016




modelling

Introduction to maintenance engineering : modelling, optimization and management

Location: Engineering Library- TS174.B455 2016




modelling

Thermo-Hydro-Mechanical-Chemical Processes in Fractured Porous Media: Modelling and Benchmarking Benchmarking Initiatives

Location: Electronic Resource- 




modelling

Modelling and Simulation of Robot Manipulators

Modelling and Simulation of Robot Manipulators



  • Science and Technical Information

modelling

rHDL modelling and the anchoring mechanism of LCAT activation

Tommaso Laurenzi
Dec 2, 2020; 0:jlr.RA120000843v1-jlr.RA120000843
Research Articles




modelling

rHDL modelling and the anchoring mechanism of LCAT activation [Research Articles]

Lecithin:cholesterol-acyl-transferase (LCAT) plays a major role in cholesterol metabolism as it is the only extracellular enzyme able to esterify cholesterol. LCAT activity is required for lipoprotein remodelling and, most specifically, for the growth and maturation of HDLs. In fact, genetic alterations affecting LCAT func- tionality may cause a severe reduction in plasma levels of HDL-cholesterol with important clinical consequences. Although several hypotheses were formulated, the exact molecular recognition mechanism between LCAT and HDLs is still unknown. We employed a combination of structural bioinformatics procedures to deepen the insights into the HDL-LCAT interplay that promotes LCAT activation and cholesterol esterification. We have generated a data-driven model of reconstituted HDL (rHDL) and studied the dynamics of an assembled rHDL::LCAT supramolecular complex, pinpointing the conformational changes originating from the interaction between LCAT and apolipoprotein A-I (apoA-I) that are necessary for LCAT activation. Specifically, we propose a mechanism in which the anchoring of LCAT lid to apoA-I helices allows the formation of a hydrophobic hood that expands LCAT active site and shields it from the solvent, allowing the enzyme to process large hydrophobic substrates.




modelling

Clock doubler SDC modelling

Hi all,

I'm trying to model the clock of a clock doubler. The doubler consists of a delay cell and an XOR gate, which generates a pulse on both the rising and falling edge of the input clock. I've created a simple module to evaluate this. In this case, DEL1 and XOR2 are standard library cells. There is a don_touch constraint on both library cells as well as on clk_d.

module top (
input wire clk,
output reg Q);

//Doubler
wire clk_d;
wire clk_2x;
DEL1 u_delay (.I(clk),.Z(clk_d));
XOR2 u_xor (.A1(clk),.A2(clk_d),.Z(clk_2x));

//FF for connecting the clock to some leaf:
always @(posedge clk_2x) Q<=~Q;

endmodule

My SDC looks like this:

create_clock [get_ports {clk}] -name clk_i -period 100
set_clock_latency -rise 0.1 [get_pins u_xor/Z]
set_clock_latency -fall 0.4 [get_pins u_xor/Z]
create_generated_clock -name clk_2x -edges {1 1 2 2 3} -source clk [get_pins u_xor/Z]

The generated clock is correctly generated but the pulse width is zero. I would be expecting that the pulse width is the difference between fall and rise latency but is not applied:

report_clocks:

report_clocks -generated:

clk_2x is disconnected from the FF after syn_generic. What can I do to model some minimum pulse width? Will innovus later on model this correctly with the delay of DEL1?




modelling

Evidence grows for dramatic brain remodelling during pregnancy

A woman's brain was scanned throughout her pregnancy, adding to the growing body of evidence that dramatic remodelling takes place in preparation for motherhood




modelling

Remodelling Signal Pathways in Prostate Cancer - A New Therapeutic Target!

medlinkCancer/medlink-causing mutations in prostate cancer hyperactivate PI3K signaling, leading to cancer cell growth. PLEKHS1, a largely unknown




modelling

Local economy, Local Investment Solutions with Geospacial Economic Modelling - 25 Jun

Unique granular modelling of over 2,000 locations across Australia uncover how fragmented and concentrated our economy is.




modelling

Kinetic analysis of kraft lignin conversion via the Fenton process: process optimization and stochastic modelling

React. Chem. Eng., 2024, Advance Article
DOI: 10.1039/D4RE00401A, Paper
Lucas Ramos, Giovani Maltempi-Mendes, Adriano Francisco Siqueira, Diovana Aparecida dos Santos Napoleão, Anuj Kumar Chandel
Lignin conversion through an advanced oxidative process.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry




modelling

On the use of modelling antagonistic enzymes to aid in temporal programming of pH and PVA–borate gelation

Mol. Syst. Des. Eng., 2024, 9,372-381
DOI: 10.1039/D3ME00138E, Paper
Open Access
Nadeem Bashir, Anna S. Leathard, Madeline McHugh, Imogen Hoffman, Fahima Shaon, Jorge A. Belgodere, Annette F. Taylor, John A. Pojman
A model was developed to help predict how enzymes can be used to temporally control the gelation of polyvinyl alcohol (PVA) with borate.
The content of this RSS Feed (c) The Royal Society of Chemistry




modelling

Polymer chemistry informed neural networks (PCINNs) for data-driven modelling of polymerization processes

Polym. Chem., 2024, 15,4580-4590
DOI: 10.1039/D4PY00995A, Paper
Nicholas Ballard, Jon Larrañaga, Kiarash Farajzadehahary, José M. Asua
A method for training neural networks to predict the outcome of polymerization processes is described that incorporates fundamental chemical knowledge. This permits generation of data-driven predictive models with limited datasets.
The content of this RSS Feed (c) The Royal Society of Chemistry




modelling

Tailoring of novel morpholine-sulphonamide linked thiazole moiety as dual targeting DHFR/DNA gyrase inhibitors: Synthesis, antimicrobial, antibiofilm activities and DFT with molecular modelling studies

New J. Chem., 2024, Accepted Manuscript
DOI: 10.1039/D3NJ05774G, Paper
Moaz M. Abdou, Essam Eliwa, Mohamed Abdel Reheim, Ahmed Abu-Rayyan, Shimaa M. Abd El-Gilil, Mohammed Abu-Elghait , Mohamed H. Sharaf, Mohamed Kalaba, Ahmed Halawa, Walid Elgammal
Herein, the chemical synthesis of new thiazoles-based benzenesulfonamide-linked morpholine 4a,b–7 via late-stage thiazolation of the corresponding thiosemicarbazone 3 was reported. The skeletal formulas of the new compounds were confirmed by...
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modelling

Renewable Energy Integration into Smart Grids: A Multidisciplinary Approach to Technology Modelling and Simulation (ICREISG), International Conference on [electronic journal].

IEEE / Institute of Electrical and Electronics Engineers Incorporated




modelling

Caveats for Economists: Epidemiology-Based Modelling of COVID19 and Model Misspecifications [electronic journal].




modelling

2020 International Conference on Renewable Energy Integration into Smart Grids: A Multidisciplinary Approach to Technology Modelling and Simulation (ICREISG) [electronic journal].

IEEE / Institute of Electrical and Electronics Engineers Incorporated




modelling

Efficient numerical modelling of magnetophoresis in millifluidic systems

Lab Chip, 2024, 24,5009-5019
DOI: 10.1039/D4LC00595C, Paper
Open Access
  This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.
Johannes Soika, Tobias Wanninger, Patrick Muschak, Anja Schnell, Sebastian P. Schwaminger, Sonja Berensmeier, Markus Zimmermann
Analytical system descriptions enable efficient 3D magnetophoresis modeling, where dimensions and fluid profile choices significantly impact results.
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modelling

Development, biological evaluation, and molecular modelling of some benzene-sulfonamide derivatives as protein tyrosine phosphatase-1B inhibitors for managing diabetes mellitus and associated metabolic disorders

RSC Med. Chem., 2024, Advance Article
DOI: 10.1039/D4MD00594E, Research Article
Nagat Ghareb, Khaled M. Darwish, Mohamed S. Nafie, Ranwa Elrayess, Noha M. Abourobe, Shaimaa A. Fattah, Reem M. Hazem, Eman T. Mehanna, Ranza Elrayess
One benzene-sulfonamide derivative exhibited potent protein tyrosine phosphatase-1B inhibition for managing diabetes mellitus and associated metabolic disorders.
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modelling

Observability and mathematics [electronic resource] : Quantum Yang-Mills theory and modelling / Boris Khots.




modelling

Co-assembly of Cellulose Nanocrystals and Gold Nanorods: Insights from Molecular Dynamics Modelling

Soft Matter, 2024, Accepted Manuscript
DOI: 10.1039/D4SM00871E, Paper
Open Access
  This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.
Jiaxin Hou, William W Sampson, Ahu Gumrah Dumanli
A coarse-grained molecular dynamics model is developed to explore the co-assembly of cellulose nanocrystals (CNCs) and gold nanorods (AuNRs) under sedimentation conditions with varying vol- umetric concentration and particle-size ratios....
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modelling

Modelling the thermoelectric effect

Register now: 28 February 2018
A webinar sponsored by COMSOL




modelling

A sequential lumped kinetic modelling approach for the co-pyrolysis of plastic mixtures with a heavy refinery intermediate product in a tubular reactor

React. Chem. Eng., 2024, Advance Article
DOI: 10.1039/D4RE00075G, Paper
Open Access
Sebastian-Mark Lorbach, Andreas E. Lechleitner, Teresa Schubert, Markus Lehner
A novel sequential approach for the lumped kinetic modelling of a plastic pyrolysis process in a tubular reactor.
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