Achacar al 3+2 de Wert el deterioro de la Universidad desvirtúa los recuerdos de cualquier estudiante. 

Due to roof damage at City Hall in the recent storms, the Bermuda Musical and Dramatic Society [BMDS] has postponed the pantomime production of the Pied Piper to January 2015, where it will will take place at the Ruth Seaton James Auditorium. A BMDS spokesperson said, “The Bermuda Musical and Dramatic Society has recently been […]

सोलापुर पुलिस ने एआईएमआईएम के राष्ट्रीय अध्यक्ष सांसद असदुद्दीन ओवैसी को नोटिस दिया. खास बात यह है कि यह नोटिस भरे मंच पर दिया गया. ओवैसी सोलापुर मध्य विधानसभा क्षेत्र के उम्मीदवार फारूक शाब्दी की प्रचार रैली में आए थे और मंच पर थे. इसी दौरान ओवैसी को  नोटिस दिया गया.

God uses an OMer working amongst Kurdish refugees in Turkey to reach a whole family through one contact.

Here Mudassar Khan has explained with an example, how to get MIME type or Content Type of a File in ASP.Net using C# and VB.Net.

Here Mudassar Khan has explained with an example, how to get MIME type (Content Type) of a File in ASP.Net MVC.

how do you communicate with your plant instrumentation? How do you see and control what's happening. Windmill lets you design your user interface

Published at LXer: Rspamd 3.10 spam filtering system brings enhanced MIME UTF8 support and negative score limits for improved email scanning. Read More......

NAFA, the National Association for Fixed Annuities, presented revered distribution leader Rod Mims with the 2024 Bo Johnson Spirit Award for Lifetime Achievement for his unwavering commitment to the financial services industry. [PR.com]

Fantastic expansive list of Mime Types

If you are creating a podcast or video feed you will need to include the appropriate mime type, the proper format is indicated below.

List of Mime Types

Mimi the Mynah by Mother Melania, illustrated by Cayce Grace Kruse. Available from Holy Assumption Monastery (Calistoga, CA; 707-942-6244)

Be Yourself: Amim’s Great Discovery, written by Stephen Muse, illustrated by Dimitra Psychogiou (Saint Tikhon’s Monastery Press, 2016).

Panto is back - oh yes it is!

For a long time, high school students have been forced to practice selecting correct answers on college scholastic ability tests. Recently, it has been suggested that schools introduce biomimicry activities for STEM education to develop students' 21st century competency. However, there have been arguments about which system is more appropriate in terms of enhancing a student's competency development. Therefore, we evaluated neurological evidence of students' competency using fMRI scans taken during the selecting a correct answer for a biology question and during a biomimicry activity. Results showed that the repetitive practice of selecting correct responses limited a student's neurological activities to the brain network of the visual cortex and the front-parietal working memory cortex. However, the biomimicry activity simultaneously involved diverse prefrontal, parietal and temporal cortexes, and the putamen, limbic and cerebellum lobes. Therefore, this study proposes that the biomimicry activities could stimulate their coordinated brain development.

Each ProLon box contains everything needed for a five day ProLon FMD experience and is designed to promote the body’s natural ability to protect and rejuvenate.

In an exclusive interview, Mimi Plange dives in to her inspiration behind her new roller shade collaboration with The Shade Store.

Fall is the season of festivals and baseball here in Korea. What are some interesting festivals taking place around the country? What is the deal with the first pitch by celebrities at the baseball...

[more...]

The synthesis, crystal structure, and a Hirshfeld surface analysis of tris­{N,N-diethyl-N'-[(4-nitro­phen­yl)(oxo)meth­yl]carbamimido­thio­ato}cobalt(III) conducted at 180 K are presented. The complex consists of three N,N-diethyl-N'-[(4-nitro­benzene)(oxo)meth­yl]carbamimido­thio­ato ligands, threefold sym­metric­ally bonded about the CoIII ion, in approximately octa­hedral coordination, which generates a triple of individually near planar metallacyclic (Co—S—C—N—C—O) rings. The overall geometry of the complex is determined by the mutual orientation of each metallacycle about the crystallographically imposed threefold axis [dihedral angles = 81.70 (2)°] and by the dihedral angles between the various planar groups within each asymmetric unit [metallacycle to benzene ring = 13.83 (7)°; benzene ring to nitro group = 17.494 (8)°]. The complexes stack in anti-parallel columns about the overline{3} axis of the space group (Poverline{3}), generating solvent-accessible channels along [001]. These channels contain ill-defined, multiply disordered, partial-occupancy solvent. Atom–atom contacts in the crystal packing predominantly (∼96%) involve hydrogen, the most abundant types being H⋯H (36.6%), H⋯O (31.0%), H⋯C (19.2%), H⋯N (4.8%), and H⋯S (4.4%).

The compounds 2',3',4',6'-tetra-O-acetyl-β-d-gluco­pyranosyl N'-cyano-N-phenyl­carbamimido­thio­ate (C22H25N3O9S, 5a), 2',3',4',6'-tetra-O-acetyl-β-d-galacto­pyranosyl N'-cyano-N-phenyl­carbamimido­thio­ate, (C22H25N3O9S, 5b), 2',3',4',6'-tetra-O-acetyl-β-d-galacto­pyranosyl N'-cyano-N-methyl­carbamimido­thio­ate (C17H23N3O9S, 5c), and 2',3',4',6'-tetra-O-acetyl-β-d-galacto­pyranosyl N'-cyano-N-p-tolyl­carbamimido­thio­ate (C23H27N3O9S, 5d) all crystallize in P212121 with Z = 4. For all four structures, the configuration across the central (formal) C=N(CN) double bond of the carbamimido­thio­ate group is Z. The torsion angles C5—O1—C1—S (standard sugar numbering) are all close to 180°, confirming the β position of the substituent. Compound 5b involves an intra­molecular hydrogen bond N—H⋯O1; in 5c this contact is the weaker branch of a three-centre inter­action, whereas in 5a and 5d the H⋯O distances are much longer and do not represent significant inter­actions. The C—N bond lengths at the central carbon atom of the carbamimido­thio­ate group are almost equal. All C—O—C=O torsion angles of the acetyl groups correspond to a synperiplanar geometry, but otherwise all four mol­ecules display a high degree of conformational flexibility, with many widely differing torsion angles for equivalent groups. In the crystal packing, 5a, 5c and 5d form layer structures involving the classical hydrogen bond N—H⋯Ncyano and a variety of ‘weak’ hydrogen bonds C—H⋯O or C—H⋯S. The packing of 5b is almost featureless and involves a large number of borderline ‘weak’ hydrogen bonds. In an appendix, a potted history of wavelength preferences for structure determination is presented and it is recommended that, even for small organic crystals in non-centrosymmetric space groups, the use of Mo radiation should be considered.

Yerbaé Brands Corp., a plant-based energy beverage company, announced the launch of two additions to its zero-calorie, zero-sugar energy lineup: Peachy Mimosa Twist and Raspberry Sorbet.

Claw Machine Extravaganza: Play, Win, and Take Home Adorable Treasures!

The long-time producer of pancake mixes and syrups changes its name to Pearl Milling Company, announces annual $1 million commitment to uplift black girls and women.

Escribir, uno de los oficios más ingratos, honestos y malpagados del mundo, se ha convertido en el deporte de moda de los televiseros. ¿Nos hemos vuelto todos locos o qué?

Escuche el programa de este martes 27 de febrero. La Luciérnaga, un espacio de humor y opinión de Caracol Radio que desde hace 31 años acompaña a sus oyentes en su regreso casa.

Dosud skrytá abstraktní struktura může zjednodušit pochopení toho, co se děje na nejzákladnější rovině reality od kvantové gravitace až po vznik časoprostoru.

Replication protein A (RPA) is a eukaryotic ssDNA-binding protein and contains three subunits: RPA70, RPA32, and RPA14. Phosphorylation of the N-terminal region of the RPA32 subunit plays an essential role in DNA metabolism in processes such as replication and damage response. Phosphorylated RPA32 (pRPA32) binds to RPA70 and possibly regulates the transient RPA70-Bloom syndrome helicase (BLM) interaction to inhibit DNA resection. However, the structural details and determinants of the phosphorylated RPA32–RPA70 interaction are still unknown. In this study, we provide molecular details of the interaction between RPA70 and a mimic of phosphorylated RPA32 (pmRPA32) using fluorescence polarization and NMR analysis. We show that the N-terminal domain of RPA70 (RPA70N) specifically participates in pmRPA32 binding, whereas the unphosphorylated RPA32 does not bind to RPA70N. Our NMR data revealed that RPA70N binds pmRPA32 using a basic cleft region. We also show that at least 6 negatively charged residues of pmRPA32 are required for RPA70N binding. By introducing alanine mutations into hydrophobic positions of pmRPA32, we found potential points of contact between RPA70N and the N-terminal half of pmRPA32. We used this information to guide docking simulations that suggest the orientation of pmRPA32 in complex with RPA70N. Our study demonstrates detailed features of the domain-domain interaction between RPA70 and RPA32 upon phosphorylation. This result provides insight into how phosphorylation tunes transient bindings between RPA and its partners in DNA resection.

Sometimes, in fact, nature is stranger than fiction

A slowed-down recording, made as part of a scientific study, shows one dog quickly mimicking another canine's expression during playtime in a park in Palermo. (Video courtesy Elisabetta Palagi)

More on biomimicry: http://j.mp/RI3OOB Scientists believe the iridescent wings of the morphos butterfly could be used in technology to benefit humans.

1. Has AIMIM’s Owaisi, the dark horse in Maharashtra elections, played a winning move?  Hindustan Times
2. Video | Maharashtra Election Will Throw Up Fractured Mandate: A Owaisi's Party Leader  NDTV
3. Owaisi backs Maratha reservation ahead of Maharashtra Assembly polls  India Today
4. Need to fight unitedly by Muslims, Maratha and Dalits: Barrister Owaisi.  Etemaad
5. No one can say Uddhav Thackrey won't go back to BJP: AIMIM  The Times of India

Chronic pain conditions affect nearly 20% of the population in the United States. Current medical interventions, such as opioid drugs, are effective at relieving pain but are accompanied by many undesirable side effects. This is one reason increased numbers of chronic pain patients have been turning to Cannabis for pain management. Cannabis contains many bioactive chemical compounds; however, current research looking into lesser-studied minor cannabinoids in Cannabis lacks uniformity between experimental groups and/or excludes female mice from investigation. This makes it challenging to draw conclusions between experiments done with different minor cannabinoid compounds between laboratories or parse out potential sex differences that could be present. We chose five minor cannabinoids found in lower quantities within Cannabis: cannabinol (CBN), cannabidivarin (CBDV), cannabigerol (CBG), 8-tetrahydrocannabinol (8-THC), and 9-tetrahydrocannabivarin (THCV). These compounds were then tested for their cannabimimetic and pain-relieving behaviors in a cannabinoid tetrad assay and a chemotherapy-induced peripheral neuropathy (CIPN) pain model in male and female CD-1 mice. We found that the minor cannabinoids we tested differed in the cannabimimetic behaviors evoked, as well as the extent. We found that CBN, CBG, and high-dose 8-THC evoked some tetrad behaviors in both sexes, while THCV and low-dose 8-THC exhibited cannabimimetic tetrad behaviors only in females. Only CBN efficaciously relieved CIPN pain, which contrasts with reports from other researchers. Together these findings provide further clarity to the pharmacology of minor cannabinoids and suggest further investigation into their mechanism and therapeutic potential.

Researchers at the Wyss Institute at Harvard University have developed a microfluidic chip that can recreate some of the features of radiation-induced lung injury. The lungs are very sensitive to radiation, and this can limit the application of radiotherapy to treat cancer. Accurately modeling radiation-induced lung injury could assist in developing new methods to prevent […]

In patients with medlinkchronic kidney disease/medlink, irreversible disease progression is triggered by the loss of podocytes, essential components of the kidney's glomerular filtration barrier.

Boston : Artech House, [2018]

Abingdon, Oxon ; New York, NY : Routledge, 2022.