collagen

Uncle Bud's Hemp + Collagen

Uncle Bud's announced the launch of Uncle Bud's Hemp + Collagen drink, an elixir designed to transform skin health and overall well-being.




collagen

PB Leiner: Collagen—Still Climbing

Collagen’s star is rising fast—but is it just a passing trend? Not according to industry experts, who say that the protein is set to become a major force in the health ingredients category.




collagen

GELITA: Collagen Protein

GELITA used this year’s virtual IFT21 event to host educational session titled, “Hot! Hot! Hot! Food Formulator’s Must-Have Ingredient: Collagen Protein.” Attendees could see connect with GELITA Food Scientist Ginger Waller and discuss original formulations with collagen proteins.




collagen

Rritual Superfoods Plant-Based Collagen Boosters

Rritual Superfoods Inc. announced that the company's product innovation and research team has completed testing on the first of its new superfood mushroom latte blend formulations, incorporating plant-based collagen enhancers as a key market differentiator.




collagen

Entenmann's x Obvi Super Collagen Protein Powder, Chocolate Chip Cookie

Obvi teamed up with Entenmann's®, a quintessential brand in baked goods, to bring consumers a collagen-boosting solution inspired by a classic treat. Obvi and Entenmann's® launched a collaborative flavor of Obvi's cult-favorite collagen protein powder, Entenmann's® x Obvi Super Collagen Protein Powder | Chocolate Chip Cookie.




collagen

Three New Varieties of Designer Collagen Powder

Designer Protein, a source for nutrient-filled protein powders, introduced Designer Collagen, an easy-to-digest and regenerative wellness supplement available. Designer Collagen is available in three flavors: French Vanilla, Toffee Swirl and Beautifully Unflavored.




collagen

Rowdy Vanilla Bean & Chocolate Collagen Protein Powders

Rowdy, known for its premium bars and collagen protein powders that are made with superfood prebiotic Yacon Root, announced its new flavors of collagen + prebiotic protein powders, Vanilla Bean and Chocolate.




collagen

4Th & Heart Protein Collagen Woke Bars

4th & Heart continues to revolutionize the ways in which consumers integrate ghee into their daily lifestyles with a the decadent protein, energy and collagen WOKE bars.




collagen

Gelita: Tap Into the Trends: Collagen, Gummies

GELITA will show how its highly functional Bioactive Collagen Peptides (BCP®), along with the other natural, allergen-free, and clean-label ingredients in its portfolio, can hold the key to on-trend product development. CONFIXXTM next-generation gelatin for fortified gummies, specific BCP® for improved mobility, and pharmaceutical gelatins for targeted fill release will be just three of the innovative solutions on show.




collagen

Pretty Tasty Ready-To-Drink Collagen Tea

Each variety of Pretty Tasty Tea’s ready-to-drink offering is formulated with high-quality collagen peptides, features natural ingredients such as carrots and black currants for color and is lightly sweetened using stevia leaf extract.




collagen

Collagen Peptides Star in New Sport and Active Nutrition Products




collagen

Role of Collagen in Anti-Aging Skin Care

It is the most abundant protein in the body! The collagen is found in the dermis layer of the skin which is the second layer of the skin and is responsible for the plumpness, strength and hydration of the skin. It is a group of proteins in fact which provides the tensile strength to the skin. It is said that collagen in the skin is more strong than steel.




collagen

Vital Proteins Debuts New Paper-Based Canister for Its Collagen Peptides

The latest step in brand's sustainability journey is expected to reduce more than 90 percent of plastic use across all canister offerings.




collagen

The Minor Phytocannabinoid Delta-8-Tetrahydrocannabinol Attenuates Collagen-Induced Arthritic Inflammation and Pain-Depressed Behaviors [Special Section: Cannabinoid Signaling in Human Health and Disease]

Patients with arthritis report using cannabis for pain management, and the major cannabinoid delta-9-tetrahydrocannabinol (9-THC) has anti-inflammatory properties, yet the effects of minor cannabinoids on arthritis are largely unknown. The goal of the present study was to determine the antiarthritic potential of the minor cannabinoid delta-8-tetrahydrocannabinol (8-THC) using the collagen-induced arthritis (CIA) mouse model. Adult male DBA/1J mice were immunized and boosted 21 days later with an emulsion of collagen and complete Freund’s adjuvant. Beginning on the day of the booster, mice were administered twice-daily injections of 8-THC (3 or 30 mg/kg), the steroid dexamethasone (2 mg/kg), or vehicle for two weeks. Dorsal-ventral paw thickness and qualitative measures of arthritis were recorded daily, and latency to fall from an inverted grid was measured on alternating days, to determine arthritis severity and functional impairment. On the final day of testing, spontaneous wire-climbing behavior and temperature preference in a thermal gradient ring were measured to assess CIA-depressed behavior. The 8-THC treatment (30 mg/kg) reduced paw swelling and qualitative signs of arthritis. 8-THC also blocked CIA-depressed climbing and CIA-induced preference for a heated floor without producing locomotor effects but did not affect latency to fall from a wire grid. In alignment with the morphologic and behavioral assessments in vivo, histology revealed that 8-THC reduced synovial inflammation, proteoglycan loss and cartilage and bone erosion in the foot joints in a dose-dependent manner. Together, these findings suggest that 8-THC not only blocked morphologic changes but also prevented functional loss caused by collagen-induced arthritis.

SIGNIFICANCE STATEMENT

Despite increasing use of cannabis products, the potential effects of minor cannabinoids are largely unknown. Here, the minor cannabinoid delta-8-tetrahydrocannabinol blocked the development of experimentally induced arthritis by preventing both pathophysiological as well as functional effects of the disease model. These data support the development of novel cannabinoid treatments for inflammatory arthritis.




collagen

Bioinspired nanovesicles derived from macrophage accelerate wound healing by promoting angiogenesis and collagen deposition

J. Mater. Chem. B, 2024, Advance Article
DOI: 10.1039/D3TB02158K, Paper
Tingrui Zhang, Zongguang Tai, Fengze Miao, Yingchao Zhao, Weifan Wang, Quangang Zhu, Zhongjian Chen
We prepared bioinspired nanovesicles by gradient extrusion to replace exosomes for wound healing. The nanovesicles have potential for transformation.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry




collagen

Intrafibrillar Calcium Carbonate Mineralization of Electrospinning Polyvinyl Alcohol/Collagen Films with Improved Mechanical and Bioactive Properties

J. Mater. Chem. B, 2024, Accepted Manuscript
DOI: 10.1039/D4TB01472C, Paper
Yin Liu, Xin Gao, Yuqi Li, Anqi Gao, Zhuozhi Zheng, Jingjiang Wei, Hongye Yang, Hang Ping, Hao Xie, Hao Wang, Weiming Wang, Zhengyi Fu
Collagen films play an essential role in guided bone regeneration (GBR) techniques, which creat space, promote cell adhesion, and induce osteogenic differentiation. It is therefore crucial to design appropriate GBR...
The content of this RSS Feed (c) The Royal Society of Chemistry




collagen

Scalable fabrication of porous membrane incorporating human extracellular matrix-like collagen for guided bone regeneration

J. Mater. Chem. B, 2024, 12,11142-11155
DOI: 10.1039/D4TB00962B, Paper
Qingyi Wang, Feng Zhou, Tiecheng Qiu, Yiling Liu, Wenxin Luo, Zhanqi Wang, Haiyun Li, E. Xiao, Qiang Wei, Yingying Wu
We fabricated a PCL/hCol membrane with an asymmetric porous structure for guided bone regeneration via nonsolvent-induced phase separation method. It shows superior mechanical and degradation properties, biocompatibility and osteoinductive effect.
The content of this RSS Feed (c) The Royal Society of Chemistry




collagen

Decorin in the spatial control of collagen mineralization

Mater. Horiz., 2024, Accepted Manuscript
DOI: 10.1039/D3MH02216A, Communication
Yuming Bai, Peng Wu, Qiufang Zhang, Feng Lin, Ling Hu, Zhisheng Zhang, Wenxia Huang, Yin Xiao, Qiliang Zuo
Understanding the molecular mechanism by which the periodontal ligament (PDL) is maintained un-calcified between two mineralized tissues (cementum and bone), may facilitate the functional repair and regeneration of the periodontium...
The content of this RSS Feed (c) The Royal Society of Chemistry




collagen

A chemiluminescence immunoassay for type IV collagen as a promising marker for liver fibrosis and cirrhosis

Anal. Methods, 2024, 16,2248-2255
DOI: 10.1039/D3AY02240D, Paper
Xiaoling Fu, Fan Zhang, Fangda Zhen, Lian Duan, Jian Zhou, Jianguo Ma
Herein, a magnetic bead-based chemiluminescence assay is reported to detect type IV collagen (col-IV) in serum samples.
The content of this RSS Feed (c) The Royal Society of Chemistry




collagen

Liquid crystalline collagen assemblies as substrates for directed alignment of human Schwann cells

Soft Matter, 2024, Advance Article
DOI: 10.1039/D4SM00534A, Paper
Open Access
  This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.
Homa Ghaiedi, Luis Carlos Pinzon Herrera, Saja Alshafeay, Leonard Harris, Jorge Almodovar, Karthik Nayani
Collagen is a key component of the extracellular matrix (ECM) and well-oriented domains of collagen are important for mimicking the local cell environment in vitro. Here, we demonstrate macroscopic alignment on collagen in 2-D substrates and 3-D hydrogels.
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The content of this RSS Feed (c) The Royal Society of Chemistry




collagen

Gelatine–collagen photo-crosslinkable 3D matrixes for skin regeneration

Biomater. Sci., 2024, 12,1738-1749
DOI: 10.1039/D3BM01849K, Paper
Open Access
Gauthier Menassol, Boudewijn van der Sanden, Laetitia Gredy, Capucine Arnol, Thibaut Divoux, Donald K. Martin, Olivier Stephan
Immediate care of skin wounds and burns is essential to repair this mechanical and chemical barrier to infections.
The content of this RSS Feed (c) The Royal Society of Chemistry




collagen

Dynamic monitoring of the fibrosis disease by a collagen targeting near infrared probe

Biomater. Sci., 2024, 12,1924-1931
DOI: 10.1039/D3BM01926H, Paper
Xiaoke Zhang, Qianwen Yang, Sensen Zhou, Cheng Li, Xiqun Jiang
A H2O2-sensitive macromolecular optical probe which can effectively bind to collagen was developed for real time noninvasive visualization of fibrotic tissues.
The content of this RSS Feed (c) The Royal Society of Chemistry




collagen

Collagen / polyester-polyurethane porous scaffolds for use in meniscal repair

Biomater. Sci., 2024, Accepted Manuscript
DOI: 10.1039/D4BM00234B, Paper
Open Access
Gaëlle Savin, Sylvain Caillol, Audrey Bethry, Eric Rondet, Michel Assor, Ghislain David, Benjamin Nottelet
Focusing on the regeneration of damaged knee meniscus, we propose a hybrid scaffold made of a poly(ester-urethane) (PEU) and collagen that combines suitable mechanical properties and degradability with enhanced biological...
The content of this RSS Feed (c) The Royal Society of Chemistry




collagen

Will eating collagen give you younger looking skin?

An expert weighs in on whether collagen-rich foods can improve skin health.




collagen

Preservation of the biological activity of undenatured type II collagen

The instant invention is the storage of Type II collagen containing tissue in carbonated water. Such Type II collagen is useful for alleviating the symptoms of arthritis in mammals as well as the treatment of arthritis in mammals. Such Type II collagen is also useful for the prevention of arthritis in mammals. The instant invention is also a method for the preparation of a nutritional supplement that includes the steps of: (a) separating water-insoluble undenatured Type II collagen containing animal tissue from animal tissue not containing Type II collagen; (b) subdividing and sterilizing said tissue under conditions which do not change the original structure of the Type II collagen to produce a subdivided and sterilized product; (c) packaging the subdivided and sterilized product in carbonated water.




collagen

Collagen fiber reconstituted rawhide and process for making

This invention describes a collagen fiber reconstituted rawhide useful in the production of pet chews, and a method for making the same. Beginning materials include animal skins with hair, depilated limed splits and leftovers from the manufacture of rawhide pet chews. The materials are pretreated, ground, subjected to acid treatment to swell and separate the collagen fibers that comprise the animal hide, further ground into pulp, vacuum filtered, mixed with a dehydration agent that chemically shrinks the expanded fibers, drained, formed and dried into sheet and finally exposed to a cross-linking agent to increase the adhesive strength of the end product. Edible materials, including meats, may be added to the solution prior to draining, to enhance the nutritional value and palatability of the final product, and the reconstituted rawhide sheets may be bleached for appearance.




collagen

Xiaflex (collagenase clostridium histolyticum)

Title: Xiaflex (collagenase clostridium histolyticum)
Category: Medications
Created: 3/3/2020 12:00:00 AM
Last Editorial Review: 3/3/2020 12:00:00 AM




collagen

Cinnamaldehyde Inhibits Inflammation of Human Synoviocyte Cells Through Regulation of Jak/Stat Pathway and Ameliorates Collagen-Induced Arthritis in Rats [Inflammation, Immunopharmacology, and Asthma]

Cinnamaldehyde (Cin), a bioactive cinnamon essential oil from traditional Chinese medicine herb Cinnamomum cassia, has been reported to have multipharmacological activities including anti-inflammation. However, its role and molecular mechanism of anti-inflammatory activity in musculoskeletal tissues remains unclear. Here, we first investigated the effects and molecular mechanisms of Cin in human synoviocyte cells. Then in vivo therapeutic effect of Cin on collagen-induced arthritis (CIA) also studied. Cell Counting Kit ‎CCK-8 assay was performed to evaluate the cell cytotoxicity. Proinflammatory cytokine expression was evaluated using quantitative polymerase chain reaction and ELISA. Protein expression was measured by western blotting. The in vivo effect of Cin (75 mg/kg per day) was evaluated in rats with CIA by gavage administration. Disease progression was assessed by clinical scoring, radiographic, and histologic examinations. Cin significantly inhibited interleukin (IL)-1β–induced IL-6, IL-8, and tumor necrosis factor-α release from human synoviocyte cells. The molecular analysis revealed that Cin impaired IL-6–induced activation of Janus kinase 2 (JAK2), signal transducer and activator of transcription 1 (STAT1), and STAT3 signaling pathway by inhibiting the phosphorylation of JAK2, STAT1, and STAT3, without affecting NF-B pathway. Cin reduced collagen-induced swollen paw volume of arthritic rats. The anti-inflammation effects of Cin were associated with decreased severity of arthritis, joint swelling, and reduced bone erosion and destruction. Furthermore, serum IL-6 level was decreased when Cin administered therapeutically to CIA rats. Cin suppresses IL-1β–induced inflammation in synoviocytes through the JAK/STAT pathway and alleviated collagen-induced arthritis in rats. These data indicated that Cin might be a potential traditional Chinese medicine–derived, disease-modifying, antirheumatic herbal drug.

SIGNIFICANCE STATEMENT

In this study, we found that cinnamaldehyde (Cin) suppressed proinflammatory cytokines secretion in rheumatology arthritis synoviocyte cells by Janus kinase/signal transducer and activator of transcription pathway. The in vivo results showed that Cin ameliorated collagen-induced arthritis in rats. These findings indicate that Cin is a potential traditional Chinese medicine–derived, disease-modifying, antirheumatic herbal drug.




collagen

'Pioneering' study reveals collagen peptide changes during digestion

Rousselot, the collagen-based ingredients producer, has revealed a new study which it says provides important answers surrounding the bioavailability of collagen peptides and the modifications they undergo during digestion.




collagen

Treatment of peyronie’s disease with combination of clostridium histolyticum collagenase and penile traction therapy: a prospective, multicenter, single-arm study




collagen

Tennis ace Andy Murray is using collagen to boost hopes of a comeback

Andy Murray is taking the anti-ageing drug collagen in his battle to return to the top in tennis following hip surgery.




collagen

Preparation and biological evaluations of collagen-like hierarchical Ti surface with superior osteogenic capabilities

J. Mater. Chem. B, 2020, Accepted Manuscript
DOI: 10.1039/D0TB00799D, Paper
Weiwei Lao, Qiaojie Luo, Yadong Chen, Wei Yao, Jiajia Xu, Lijie Fan, Xiaodong Li
The construction of multiscale Ti surfaces of high osteogenic ability always attracts numerous attentions in oral implantology and implantable biomaterial field. However, so far, the absence of solid understanding of...
The content of this RSS Feed (c) The Royal Society of Chemistry




collagen

Beyond temperature: controlling collagen fibrillogenesis under physiological conditions via interaction with cucurbit[7]uril

Chem. Commun., 2020, 56,4946-4949
DOI: 10.1039/D0CC01444C, Communication
Qiuping Xie, Delong Hou, Jinming Chang, Zhou Xu, Qi Zeng, Zhonghui Wang, Yi Chen
A supramolecular strategy as efficient as temperature that enabled facile control over collagen fibrillogenesis under physiological conditions was reported.
The content of this RSS Feed (c) The Royal Society of Chemistry




collagen

Collagen: from tissue culture to biomaterials, tissue engineering, and beyond / by Elena García-Gareta

Barker Library - QP552.C6 G37 2019




collagen

Bioactive scaffolds based on collagen filaments with tunable physico-chemical and biological features

Soft Matter, 2020, Advance Article
DOI: 10.1039/D0SM00233J, Paper
Ting Lu, Hong Hu, Yuanqi Li, Qingsong Jiang, Jinlei Su, Hai Lin, Yun Xiao, Xiangdong Zhu, Xingdong Zhang
Native tissues such as nerve bundles, blood vessels and tendons have extracellular matrices with a characteristic linear orientation, which cannot be fully achieved with the current technology for the development of regenerative biomaterials.
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The content of this RSS Feed (c) The Royal Society of Chemistry




collagen

Evonik rolls out nonanimal collagen




collagen

The prophylactic effects of different Lactobacilli on collagen-induced arthritis in rats

Food Funct., 2020, 11,3681-3694
DOI: 10.1039/C9FO02556A, Paper
Zhexin Fan, Bo Yang, R. Paul Ross, Catherine Stanton, Jianxin Zhao, Hao Zhang, Wei Chen
The current study evaluated the prophylactic effects of different Lactobacillus species on arthritis induced by collagen.
The content of this RSS Feed (c) The Royal Society of Chemistry




collagen

Protective effects of Bifidobacterium adolescentis on collagen-induced arthritis in rats depend on timing of administration

Food Funct., 2020, Advance Article
DOI: 10.1039/D0FO00077A, Paper
Zhexin Fan, Bo Yang, R. Paul Ross, Catherine Stanton, Guoxun Shi, Jianxin Zhao, Hao Zhang, Wei Chen
Early probiotics adminitration is a key timing to alleviate inflammation in rats with arthritis.
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The content of this RSS Feed (c) The Royal Society of Chemistry




collagen

[ASAP] Collagen-Targeted Theranostic Nanosponges for Delivery of the Matrix Metalloproteinase 14 Inhibitor Naphthofluorescein

Chemistry of Materials
DOI: 10.1021/acs.chemmater.9b02840




collagen

Detection, cloning, and analysis of a u32 collagenase in streptococcus mutans gs-5




collagen

Transport characteristics using nor-dihydroguaiaretic acid (NDGA)-polymerized collagen fibers as a local drug delivery system




collagen

A novel bio-stable 3D porous collagen scaffold for implantable biosensor




collagen

Bat wing biometrics: using collagen–elastin bundles in bat wings as a unique individual identifier




collagen

Destructin-1 is a collagen-degrading endopeptidase secreted by Pseudogymnoascus destructans, the causative agent of white-nose syndrome




collagen

Identification of a new hominin bone from Denisova Cave, Siberia using collagen fingerprinting and mitochondrial DNA analysis




collagen

[ASAP] Cell-Laden Biomimetically Mineralized Shark-Skin-Collagen-Based 3D Printed Hydrogels for the Engineering of Hard Tissues

ACS Biomaterials Science & Engineering
DOI: 10.1021/acsbiomaterials.0c00436




collagen

[ASAP] Alginate-Assisted Mineralization of Collagen by Collagen Reconstitution and Calcium Phosphate Formation

ACS Biomaterials Science & Engineering
DOI: 10.1021/acsbiomaterials.9b01841