bariatric surgery

The Rapid Growth of GLP-1s and Their Impact on Bariatric Surgery

Bariatric surgery is still the gold standard for morbid obesity treatment, yet patients and medical professionals will likely seek less invasive weight loss drugs before considering bariatric surgery. 

The post The Rapid Growth of GLP-1s and Their Impact on Bariatric Surgery appeared first on MedCity News.




bariatric surgery

Psychological Evaluation Standards for Pre-Operative Bariatric Surgery

Veterans Administration Bariatric Surgery Workgroup standards for bariatric surgery psychological evaluations - 2007.




bariatric surgery

How Bariatric Surgery Offers Hope for Diabetic Kidney Patients

Bariatric surgery outperforms GLP-1 diabetes drugs in protecting kidney function, according to a study.




bariatric surgery

Bariatric Surgery Cuts Cancer Risk by 80% in Obese Patients: Study

According to a new Canadian study morbidly obese patients who have surgery to reduce their stomach size could lower their risk of developing cancer by about 80 per cent.




bariatric surgery

Bariatric Surgery Things You Should Be Aware Of

When all other measures fail to control morbid obesity, weight loss surgery is a source of hope to the overweight. American doctors perform weight loss surgery over 140,000 times a year. The oldest form of weight loss surgery is the most familiar, stomach stapling. In this 30-year-old procedure, most of the stomach is sliced and then stapled shut.




bariatric surgery

Jet Medical Tourism® Cites Major New Research Published by JAMA Network That Says Bariatric Surgery Reduces Heart Disease Risks

Severely obese patients often live with the constant fear that they may suffer a heart attack because of their low physical activity, poor metabolism, and the extra pressure on their heart caused by their excessive body weight.




bariatric surgery

Bariatric Surgery Rapidly Decreases Cardiac Dietary Fatty Acid Partitioning and Hepatic Insulin Resistance Through Increased Intra-abdominal Adipose Tissue Storage and Reduced Spillover in Type 2 Diabetes

Reduced storage of dietary fatty acids (DFAs) in abdominal adipose tissues with enhanced cardiac partitioning has been shown in subjects with type 2 diabetes (T2D) and prediabetes. We measured DFA metabolism and organ partitioning using positron emission tomography with oral and intravenous long-chain fatty acid and glucose tracers during a standard liquid meal in 12 obese subjects with T2D before and 8–12 days after bariatric surgery (sleeve gastrectomy or sleeve gastrectomy and biliopancreatic diversion with duodenal switch). Bariatric surgery reduced cardiac DFA uptake from a median (standard uptake value [SUV]) 1.75 (interquartile range 1.39–2.57) before to 1.09 (1.04–1.53) after surgery (P = 0.01) and systemic DFA spillover from 56.7 mmol before to 24.7 mmol over 6 h after meal intake after surgery (P = 0.01), with a significant increase in intra-abdominal adipose tissue DFA uptake from 0.15 (0.04–0.31] before to 0.49 (0.20–0.59) SUV after surgery (P = 0.008). Hepatic insulin resistance was significantly reduced in close association with increased DFA storage in intra-abdominal adipose tissues (r = –0.79, P = 0.05) and reduced DFA spillover (r = 0.76, P = 0.01). We conclude that bariatric surgery in subjects with T2D rapidly reduces cardiac DFA partitioning and hepatic insulin resistance at least in part through increased intra-abdominal DFA storage and reduced spillover.




bariatric surgery

Late Relapse of Diabetes After Bariatric Surgery: Not Rare, but Not a Failure

OBJECTIVE

To characterize the status of cardiometabolic risk factors after late relapse of type 2 diabetes mellitus (T2DM) and to identify factors predicting relapse after initial diabetes remission following bariatric surgery to construct prediction models for clinical practice.

RESEARCH DESIGN AND METHODS

Outcomes of 736 patients with T2DM who underwent Roux-en-Y gastric bypass (RYGB) or sleeve gastrectomy (SG) at an academic center (2004–2012) and had ≥5 years’ glycemic follow-up were assessed. Of 736 patients, 425 (58%) experienced diabetes remission (HbA1c <6.5% [48 mmol/mol] with patients off medications) in the 1st year after surgery. These 425 patients were followed for a median of 8 years (range 5–14) to characterize late relapse of diabetes.

RESULTS

In 136 (32%) patients who experienced late relapse, a statistically significant improvement in glycemic control, number of diabetes medications including insulin use, blood pressure, and lipid profile was still observed at long-term. Independent baseline predictors of late relapse were preoperative number of diabetes medications, duration of T2DM before surgery, and SG versus RYGB. Furthermore, patients who relapsed lost less weight during the 1st year after surgery and regained more weight afterward. Prediction models were constructed and externally validated.

CONCLUSIONS

While late relapse of T2DM is a real phenomenon (one-third of our cohort), it should not be considered a failure, as the trajectory of the disease and its related cardiometabolic risk factors is changed favorably after bariatric surgery. Earlier surgical intervention, RYGB (compared with SG) and more weight loss (less late weight regain) are associated with less diabetes relapse in the long-term.




bariatric surgery

Effects of Bariatric Surgery in Early- and Adult-Onset Obesity in the Prospective Controlled Swedish Obese Subjects Study

OBJECTIVE

Bariatric surgery is an effective treatment for obesity, but it is unknown if outcomes differ between adults with early- versus adult-onset obesity. We investigated how obesity status at 20 years of age affects outcomes after bariatric surgery later in life.

RESEARCH DESIGN AND METHODS

The Swedish Obese Subjects study is a prospective matched study performed at 25 surgical departments and 480 primary health care centers. Participants aged 37–60 years with BMI ≥34 kg/m2 (men) or ≥38 kg/m2 (women) were recruited between 1987 and 2001; 2,007 participants received bariatric surgery and 2,040 usual care. Self-reported body weight at 20 years of age was used to stratify patients into subgroups with normal BMI (<25 kg/m2), overweight (BMI 25–29.9 kg/m2), or obesity (BMI ≥30 kg/m2). Body weight, energy intake, and type 2 diabetes status were examined over 10 years, and incidence of cardiovascular and microvascular disease was determined over up to 26 years using data from health registers.

RESULTS

There were small but statistically significant differences in reduction of body weight among the subgroups after bariatric surgery (interaction P = 0.032), with the largest reductions among those with obesity aged 20 years. Bariatric surgery increased type 2 diabetes remission (odds ratios 4.51, 4.90, and 5.58 in subgroups with normal BMI, overweight, or obesity at 20 years of age, respectively; interaction P = 0.951), reduced type 2 diabetes incidence (odds ratios 0.15, 0.13, and 0.15, respectively; interaction P = 0.972), and reduced microvascular complications independent of obesity status at 20 years of age (interaction P = 0.650). The association between bariatric surgery and cardiovascular disease was similar in the subgroups (interaction P = 0.674). Surgical complications were similar in the subgroups.

CONCLUSIONS

The treatment benefits of bariatric surgery in adults are similar regardless of obesity status at 20 years of age.




bariatric surgery

How Dangerous Is Bariatric Surgery?

Title: How Dangerous Is Bariatric Surgery?
Category: Procedures and Tests
Created: 3/18/2020 12:00:00 AM
Last Editorial Review: 3/18/2020 12:00:00 AM




bariatric surgery

Bariatric Surgery in Patients With Obesity and Latent Autoimmune Diabetes in Adults (LADA)




bariatric surgery

Promise of T1D Vaccines; Can Bariatric Surgery Be Essential?

(MedPage Today) -- Researchers developed a potential vaccine for a certain type of virus infection that leads to an autoimmune attack, which may result in turn in part to the development of type 1 diabetes. "Our hope is that these trials will show...




bariatric surgery

Predictors of weight loss after bariatric surgery—a cross-disciplinary approach combining physiological, social, and psychological measures




bariatric surgery

Unconscious Food Impulses may Make Bariatric Surgery Less Effective for Extreme Obesity: Study

Unconscious food cravings were found to make bariatric surgery less effective for extreme obesity, stated new research that was accepted for presentation




bariatric surgery

Greater Weight Loss Achieved Through Bariatric Surgery Before Diabetes Development

Obese patients may lose more weight if they undergo bariatric surgery before they develop diabetes. Both obesity and diabetes are common, serious and costly in United States.






bariatric surgery

Prevalence of Alcohol Use Disorders Before and After Bariatric Surgery

Interview with Wendy C. King, PhD, author of Prevalence of Alcohol Use Disorders Before and After Bariatric Surgery




bariatric surgery

Bariatric Surgery Complications Before vs After Implementation of a National Policy Restricting Coverage to Centers of Excellence

Interview with Justin B. Dimick, MD, MPH, author of Bariatric Surgery Complications Before vs After Implementation of a National Policy Restricting Coverage to Centers of Excellence




bariatric surgery

Weight Change and Health Outcomes at 3 Years After Bariatric Surgery Among Individuals With Severe Obesity

Interview with Anita P. Courcoulas, MD, MPH, author of Weight Change and Health Outcomes at 3 Years After Bariatric Surgery Among Individuals With Severe Obesity




bariatric surgery

Association Between Bariatric Surgery and Long-term Survival

Interview with David E. Arterburn, MD, MPH and Matthew L. Maciejewski, PhD, authors of Association Between Bariatric Surgery and Long-term Survival