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Episode 536: Ryan Magee on Software Engineering in Physics Research

Ryan Magee, postdoctoral scholar research associate at LIGO Laboratory – Caltech, joins host Jeff Doolittle for a conversation about how software is used by scientists in physics research. The episode begins with a discussion of gravitational waves...




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Baby Christmas Milestone Cards $0.99 each & More + Delivery ($0 with $200 Spend) @ magoo & magee

Snuggle Hunny branded Christmas Milestone Cards usually $4.95 reduced to $0.99 as part of Black Friday sale.




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340: ‘Billionaires Have Beefs’, With Tom Watson and Daniel Agee

Special guests Tom Watson and Daniel Agee join the show to talk about Glass, their upstart photo sharing app and community.




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The structure of a family 110 glycoside hydrolase provides insight into the hydrolysis of {alpha}-1,3-galactosidic linkages in {lambda}-carrageenan and blood group antigens [Enzymology]

α-Linked galactose is a common carbohydrate motif in nature that is processed by a variety of glycoside hydrolases from different families. Terminal Galα1–3Gal motifs are found as a defining feature of different blood group and tissue antigens, as well as the building block of the marine algal galactan λ-carrageenan. The blood group B antigen and linear α-Gal epitope can be processed by glycoside hydrolases in family GH110, whereas the presence of genes encoding GH110 enzymes in polysaccharide utilization loci from marine bacteria suggests a role in processing λ-carrageenan. However, the structure–function relationships underpinning the α-1,3-galactosidase activity within family GH110 remain unknown. Here we focus on a GH110 enzyme (PdGH110B) from the carrageenolytic marine bacterium Pseudoalteromonas distincta U2A. We showed that the enzyme was active on Galα1–3Gal but not the blood group B antigen. X-ray crystal structures in complex with galactose and unhydrolyzed Galα1–3Gal revealed the parallel β-helix fold of the enzyme and the structural basis of its inverting catalytic mechanism. Moreover, an examination of the active site reveals likely adaptations that allow accommodation of fucose in blood group B active GH110 enzymes or, in the case of PdGH110, accommodation of the sulfate groups found on λ-carrageenan. Overall, this work provides insight into the first member of a predominantly marine clade of GH110 enzymes while also illuminating the structural basis of α-1,3-galactoside processing by the family as a whole.





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ZOHO ManageEngine ADSelfService Plus 4.5 Build 4521 Administrative Access

ZOHO ManageEngine ADSelfService Plus version 4.5 Build 4521 suffers from an authentication bypass vulnerability.




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Mortgagee’s power of sale does not offend human rights

Realisation of security by mortgagees is a hot topic in current economic circumstances, and Horsham Properties Group Ltd v Clark is a case that underlines that mortgagees' powers can sometimes appear draconian. In this case, the mortgagee appointed...




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What is carrageenan?

Carrageenan is in everything from dairy products to toothpaste. Here's what you need to know about the natural but controversial additive.




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Martin Bloomberg Joins Leageez as VP of Marketing

David Saad to focus on national sports retail allliances.




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ManageEngine DataSecurity Plus Authentication Bypass

ManageEngine DataSecurity Plus versions prior to 6.0.1 and ADAudit Plus versions prior to 6.0.3 suffer from an authentication bypass vulnerability.




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ManageEngine 14 Remote Code Execution

This is a whitepaper tutorial that describes steps taken to identify post-authentication remote code execution vulnerabilities in ManageEngine version 14.




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ManageEngine DataSecurity Plus Path Traversal / Code Execution

ManageEngine DataSecurity Plus versions prior to 6.0.1 and ADAudit Plus versions prior to 6.0.3 suffers from a path traversal vulnerability that can lead to remote code execution.




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ManageEngine Asset Explorer Windows Agent Remote Code Execution

The ManageEngine Asset Explorer windows agent suffers form a remote code execution vulnerability. All versions prior to 1.0.29 are affected.




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ManageEngine EventLog Analyzer 10.0 Information Disclosure

ManageEngine EventLog Analyzer version 10.0 suffers from an information disclosure vulnerability.




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A field guide to community based adaptation [electronic resource] / Tim Magee ; with a foreword by Howard White

Magee, Tim




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Over Here, Over There: Transatlantic Conversations on the Music of World War I / edited by WIlliam Brooks, Christina Bashford, and Gayle Magee

Lewis Library - ML3551.5.B76 2019