science and technology Global Problem, Local Solutions By feedproxy.google.com Published On :: Apr 21, 2020 Apr 21, 2020The Arctic Initiative is pairing policy and science scholars with local experts to find practical climate solutions. Full Article
science and technology This Virus Is Tough, but History Provides Perspective: The 1968 Pandemic and the Vietnam War By feedproxy.google.com Published On :: Apr 24, 2020 Apr 24, 2020Nathaniel L. Moir recounts the events of 1968: The war in Vietnam and extensive civil unrest in the United States — and yet another big problem that made life harder. In 1968, the H3N2 pandemic killed more individuals in the United States than the combined total number of American fatalities during both the Vietnam and Korean Wars. Full Article
science and technology How COVID-19 is Testing American Leadership By feedproxy.google.com Published On :: Apr 26, 2020 Apr 26, 2020Joseph Nye suggests that a new U.S. administration might take a leaf from the success of the post-1945 American presidents that are described in Do Morals Matter? Presidents and Foreign Policy from FDR to Trump. The United States could launch a massive COVID-19 aid program like the Marshall Plan. Full Article
science and technology Poll: What the American Public Likes and Hates about Trump's Nuclear Policies By feedproxy.google.com Published On :: Apr 27, 2020 Apr 27, 2020The authors conducted a study which highlights how the U.S. public as a whole and various demographic groups view President Donald Trump's positions on nuclear weapons. Full Article
science and technology Why Bernie Sanders Will Win in 2020, No Matter Who Gets Elected By feedproxy.google.com Published On :: Apr 28, 2020 Apr 28, 2020Stephen Walt writes that even though Bernie Sanders is out of the presidential race, the time has come for many of the policies that he promoted: Universal Healthcare; Democratic Socialism; Income Redistribution; and Foreign Policy. Full Article
science and technology The U.S. Is Now Resorting to Plan C By feedproxy.google.com Published On :: Apr 29, 2020 Apr 29, 2020Americans are not going to wait for sufficient testing. So what happens then? Juliette Kayyem describes "opening up" as a high-stakes version of a coloring book. States can use more and more crayons, but the goal is to avoid going over the edges. Full Article
science and technology What I Wish I Had Said on CNN About Trump's 'Lysol and Sunshine' Speech By feedproxy.google.com Published On :: Apr 29, 2020 Apr 29, 2020Joel Clement appeared on CNN's Erin Burnett OutFront on April 23, 2020. In this blog post for the Union of Concerned Scientists, he elaborates on what he wishes he had said during that interview. Full Article
science and technology The Arctic is Transforming… Can We? By feedproxy.google.com Published On :: May 1, 2020 May 1, 2020Joel Clement describes how the Arctic is transforming into a warmer, wetter, and less predictable climate state, what the consequences are for the Arctic's indigenous inhabitants, and what measures can be taken to build resilience. Full Article
science and technology Trump Turned the Death Count Into a Story About Himself By feedproxy.google.com Published On :: May 7, 2020 May 7, 2020Official figures exclude thousands who have died during the pandemic. To draw the right lessons, the United States needs an accurate tally of the victims. Full Article
science and technology An Abysmal Failure of Leadership By feedproxy.google.com Published On :: May 7, 2020 May 7, 2020During times of crisis, the most effective leaders are those who can build solidarity by educating the public about its own interests. Sadly, in the case of COVID-19, the leaders of the world's two largest economies have gone in the opposite direction, all but ensuring that the crisis will deepen. Full Article
science and technology Next Moves on Climate Policy: A Conversation with Sue Biniaz By feedproxy.google.com Published On :: May 8, 2020 May 8, 2020Sue Biniaz, former lead climate negotiator for the United States, shared her thoughts on the postponement of COP-26, and on the possible re-engagement of the U.S. in the international effort to address climate change in the newest episode of “Environmental Insights: Discussions on Policy and Practice from the Harvard Environmental Economics Program,” a podcast produced by the Harvard Environmental Economics Program. Full Article
science and technology Genome-wide selection and genetic improvement during modern maize breeding By feeds.nature.com Published On :: 2020-04-27 Full Article
science and technology Genetic identification of cell types underlying brain complex traits yields insights into the etiology of Parkinson’s disease By feeds.nature.com Published On :: 2020-04-27 Full Article
science and technology Author Correction: Comprehensive molecular characterization of mitochondrial genomes in human cancers By feeds.nature.com Published On :: 2020-04-27 Full Article
science and technology Author Correction: <i>Cdkn1a</i> deletion improves stem cell function and lifespan of mice with dysfunctional telomeres without accelerating cancer formation By feeds.nature.com Published On :: 2020-04-30 Full Article
science and technology Elevated sorbitol underlies a heritable neuropathy By feeds.nature.com Published On :: 2020-05-04 Full Article
science and technology Biallelic mutations in <i>SORD</i> cause a common and potentially treatable hereditary neuropathy with implications for diabetes By feeds.nature.com Published On :: 2020-05-04 Full Article
science and technology Enhancer–promoter interactions and transcription By feeds.nature.com Published On :: 2020-05-06 Full Article
science and technology Tracking genetic discrimination By feeds.nature.com Published On :: 2020-05-06 Full Article
science and technology ZBP1 (DAI/DLM-1) promotes osteogenic differentiation while inhibiting adipogenic differentiation in mesenchymal stem cells through a positive feedback loop of Wnt/β-catenin signaling By feeds.nature.com Published On :: 2020-03-05 Full Article
science and technology The cartilage matrisome in adolescent idiopathic scoliosis By feeds.nature.com Published On :: 2020-03-09 Full Article
science and technology Mitigating osteonecrosis of the jaw (ONJ) through preventive dental care and understanding of risk factors By feeds.nature.com Published On :: 2020-03-11 Full Article
science and technology Correction to: AFF1 and AFF4 differentially regulate the osteogenic differentiation of human MSCs By feeds.nature.com Published On :: 2020-03-31 Full Article
science and technology Dystrophic calcification and heterotopic ossification in fibrocartilaginous tissues of the spine in diffuse idiopathic skeletal hyperostosis (DISH) By feeds.nature.com Published On :: 2020-04-02 Full Article
science and technology Correction: Humanized bone facilitates prostate cancer metastasis and recapitulates therapeutic effects of Zoledronic acid in vivo By feeds.nature.com Published On :: 2020-04-03 Full Article
science and technology uPAR antibody (huATN-658) and Zometa reduce breast cancer growth and skeletal lesions By feeds.nature.com Published On :: 2020-04-17 Full Article
science and technology Ionomycin ameliorates hypophosphatasia via rescuing alkaline phosphatase deficiency-mediated L-type Ca<sup>2+</sup> channel internalization in mesenchymal stem cells By feeds.nature.com Published On :: 2020-04-26 Full Article
science and technology Stepping Back from the Brink on Iran By feedproxy.google.com Published On :: Jan 8, 2020 Jan 8, 2020Neither the United States nor Iran wants to go to war. That’s the good news. The bad news is that in the fog of crisis — similar in many ways to the fog of war — the danger of inadvertently stumbling into war is dangerously high. Full Article
science and technology The Overwhelming Case for No First Use By feedproxy.google.com Published On :: Jan 13, 2020 Jan 13, 2020The arguments in favor of the United States' declaring that the only purpose of its nuclear weapons is to deter others who possess them from using theirs — in other words, that in no circumstances will this country use nuclear weapons first — are far stronger than the arguments against this stance. It must be hoped that the next US administration will take this no-first-use step promptly. Full Article
science and technology Why is the United States So Bad at Foreign Policy? By feedproxy.google.com Published On :: Jan 13, 2020 Jan 13, 2020Stephen Walt writes that the United States' unusual historical experience, geographic isolation, large domestic market, and general ignorance have weakened its ability to make viable foreign-policy strategies. Full Article
science and technology The U.S.-China Relationship is at a Crossroads By feedproxy.google.com Published On :: Jan 15, 2020 Jan 15, 2020Joseph Nye writes that some decoupling of interdependence is likely, particularly in areas related to technology that directly affect national security. But will Washington and Beijing go too far? Full Article
science and technology What Makes for a Moral Foreign Policy? By feedproxy.google.com Published On :: Jan 21, 2020 Jan 21, 2020Joseph Nye's new book rates the efforts of presidents from FDR to Trump. Full Article
science and technology The Low-Yield Nuclear Warhead: A Dangerous Weapon Based on Bad Strategic Thinking By feedproxy.google.com Published On :: Jan 28, 2020 Jan 28, 2020In the unintuitive world of nuclear weapons strategy, it’s often difficult to identify which decisions can serve to decrease the risk of a devastating nuclear conflict and which might instead increase it. Such complexity stems from the very foundation of the field: Nuclear weapons are widely seen as bombs built never to be used. Historically, granular—even seemingly mundane—decisions about force structure, research efforts, or communicated strategy have confounded planners, sometimes causing the opposite of the intended effect. Full Article
science and technology Accumulating Evidence Using Crowdsourcing and Machine Learning: A Living Bibliography about Existential Risk and Global Catastrophic Risk By feedproxy.google.com Published On :: Feb 3, 2020 Feb 3, 2020The study of existential risk — the risk of human extinction or the collapse of human civilization — has only recently emerged as an integrated field of research, and yet an overwhelming volume of relevant research has already been published. To provide an evidence base for policy and risk analysis, this research should be systematically reviewed. In a systematic review, one of many time-consuming tasks is to read the titles and abstracts of research publications, to see if they meet the inclusion criteria. The authors show how this task can be shared between multiple people (using crowdsourcing) and partially automated (using machine learning), as methods of handling an overwhelming volume of research. Full Article
science and technology The Need for Creative and Effective Nuclear Security Vulnerability Assessment and Testing By feedproxy.google.com Published On :: Feb 10, 2020 Feb 10, 2020Realistic, creative vulnerability assessment and testing are critical to finding and fixing nuclear security weaknesses and avoiding over-confidence. Both vulnerability assessment and realistic testing are needed to ensure that nuclear security systems are providing the level of protection required. Systems must be challenged by experts thinking like adversaries, trying to find ways to overcome them. Effective vulnerability assessment and realistic testing are more difficult in the case of insider threats, and special attention is needed. Organizations need to find ways to give people the mission and the incentives to find nuclear security weaknesses and suggest ways they might be fixed. With the right approaches and incentives in place, effective vulnerability assessment and testing can be a key part of achieving and sustaining high levels of nuclear security. Full Article
science and technology The Risks and Rewards of Emerging Technology in Nuclear Security By feedproxy.google.com Published On :: Feb 10, 2020 Feb 10, 2020Nuclear security is never finished. Nuclear security measures for protecting all nuclear weapons, weapons-usable nuclear materials, and facilities whose sabotage could cause disastrous consequences should protect against the full range of plausible threats. It is an ongoing endeavor that requires constant assessment of physical protection operations and reevaluation of potential threats. One of the most challenging areas of nuclear security is how to account for the impact–positive and negative—of non-nuclear emerging technologies. The amended Convention on the Physical Protection of Nuclear Material (amended CPPNM) states it should be reviewed in light of the prevailing situation, and a key part of the prevailing situation is technological evolution. Therefore, the upcoming review conference in 2021, as well as any future review conferences, should examine the security threats and benefits posed by emerging technologies. Full Article
science and technology The Past and Potential Role of Civil Society in Nuclear Security By feedproxy.google.com Published On :: Feb 10, 2020 Feb 10, 2020Civil society has played a very important role in nuclear security over the years, and its role could be strengthened in the future. Some nuclear organizations react against the very idea of civil society involvement, thinking of only one societal role—protesting. In fact, however, civil society has played quite a number of critical roles in nuclear security over the years, including highlighting the dangers of nuclear terrorism; providing research and ideas; nudging governments to act; tracking progress and holding governments and operators accountable; educating the public and other stakeholders; promoting dialogue and partnerships; helping with nuclear security implementation; funding initial steps; and more. Funding organizations (both government and non-government) should consider ways to support civil society work and expertise focused on nuclear security in additional countries. Rather than simply protesting and opposing, civil society organizations can help build more effective nuclear security practices around the world. Full Article
science and technology Assessing Progress on Nuclear Security Action Plans By feedproxy.google.com Published On :: Feb 10, 2020 Feb 10, 2020Participants at the final Nuclear Security Summit in 2016 agreed on “action plans” for initiatives they would support by five international organizations and groups—the International Atomic Energy Agency, the Global Initiative to Combat Nuclear Terrorism, INTERPOL, the United Nations, and the Global Partnership Against the Spread of Weapons and Materials of Destruction. These institutions were supposed to play key roles in bolstering ongoing nuclear security cooperation after the summit process ended. The action plans were modest documents, largely endorsing activities already underway, and there have been mixed results in implementing them. To date, these organizations have not filled any substantial part of the role once played by the nuclear security summits. Full Article
science and technology Arms Control Agreement With Russia Should Cover More Than Nuclear Weapons By feedproxy.google.com Published On :: Feb 23, 2020 Feb 23, 2020With the Russia investigation and impeachment behind him, President Trump finally may feel empowered to engage with Russian President Vladimir Putin and pursue an arms control deal. Full Article
science and technology How Do Past Presidents Rank in Foreign Policy? By feedproxy.google.com Published On :: Mar 2, 2020 Mar 2, 2020How do presidents incorporate morality into decisions involving the national interest? Moral considerations explain why Truman, who authorized the use of nuclear weapons in Japan during World War II, later refused General MacArthur's request to use them in China during the Korean War. What is contextual intelligence, and how does it explain why Bush 41 is ranked first in foreign policy, but Bush 43 is found wanting? Is it possible for a president to lie in the service of the public interest? In this episode, Professor Joseph S. Nye considers these questions as he explores the role of morality in presidential decision-making from FDR to Trump. Full Article
science and technology Secrecy, Public Relations and the British Nuclear Debate By feedproxy.google.com Published On :: Mar 5, 2020 Mar 5, 2020The opening of the British archives has seen historians uncover the secrets of the UK's nuclear weapons programme since the 1990s. While a growing number have sought to expose these former secrets, there has been less effort to consider government secrecy itself. What was kept a secret, when and why? And how and why, notably from the 1980s, did the British government decide to officially disclose greater information about the British nuclear weapons programme to Members of Parliament, journalists, defence academics and the tax-paying general public. Full Article
science and technology Budapest Memorandum at 25: Between Past and Future By feedproxy.google.com Published On :: Mar 17, 2020 Mar 17, 2020On December 5, 1994, leaders of the United States, the United Kingdom, and the Russian Federation met in Budapest, Hungary, to pledge security assurances to Ukraine in connection with its accession to the Treaty on the Nonproliferation of Nuclear Weapons (NPT) as a non-nuclear-weapons state. The signature of the so-called Budapest Memorandum concluded arduous negotiations that resulted in Ukraine’s agreement to relinquish the world’s third-largest nuclear arsenal, which the country inherited from the collapsed Soviet Union, and transfer all nuclear warheads to Russia for dismantlement. The signatories of the memorandum pledged to respect Ukraine’s territorial integrity and inviolability of its borders, and to refrain from the use or threat of military force. Russia breached these commitments with its annexation of Crimea in 2014 and aggression in eastern Ukraine, bringing the meaning and value of security assurance pledged in the Memorandum under renewed scrutiny. On the occasion of the 25th anniversary of the memorandum’s signature, the Project on Managing the Atom at the Belfer Center for Science & International Affairs at the Harvard Kennedy School, with the support of the Center for U.S.-Ukrainian Relations and the Harvard Ukrainian Research Institute, hosted a conference to revisit the history of the Budapest Memorandum, consider the repercussions of its violation for international security and the broader nonproliferation regime, and draw lessons for the future. The conference brought together academics, practitioners, and experts who have contributed to developing U.S. policy toward post-Soviet nuclear disarmament, participated in the negotiations of the Budapest Memorandum, and dealt with the repercussions of its breach in 2014. The conference highlighted five key lessons learned from the experience of Ukraine’s disarmament, highlighted at the conference. Full Article
science and technology Public Testimony on Trump Administration Funding for Nuclear Theft Preventing Programs By feedproxy.google.com Published On :: Mar 31, 2020 Mar 31, 2020A nuclear explosion detonated anywhere by a terrorist group would be a global humanitarian, economic, and political catastrophe. The current COVID-19 pandemic reminds us not to ignore prevention of and preparation for low-probability, high-consequence disasters. For nuclear terrorism, while preparation is important, prevention must be the top priority. The most effective strategy for keeping nuclear weapons out of the hands of terrorists is to ensure that nuclear materials and facilities around the world have strong and sustainable security. Every president for more than two decades has made strengthening nuclear security around the globe a priority. This includes the Trump administration, whose 2018 Nuclear Posture Review states: “[n]uclear terrorism remains among the most significant threats to the security of the United States, allies, and partners.” Full Article
science and technology Living with Uncertainty: Modeling China's Nuclear Survivability By feedproxy.google.com Published On :: Apr 11, 2020 Apr 11, 2020A simplified nuclear exchange model demonstrates that China’s ability to launch a successful nuclear retaliatory strike in response to an adversary’s nuclear first strike has been and remains far from assured. This study suggests that China’s criterion for effective nuclear deterrence is very low. Full Article
science and technology So Do Morals Matter in U.S. Foreign Policy? I Asked the Expert. By feedproxy.google.com Published On :: Apr 24, 2020 Apr 24, 2020In his new book, Do Morals Matter? Presidents and Foreign Policy from FDR to Trump, Joseph S. Nye developed a scorecard to determine how U.S. presidents since 1945 factored questions of ethics and morality into their foreign policy. In an interview, Henry Farrell asked him a few questions to get to the heart of his findings. Full Article
science and technology Poll: What the American Public Likes and Hates about Trump's Nuclear Policies By feedproxy.google.com Published On :: Apr 27, 2020 Apr 27, 2020The authors conducted a study which highlights how the U.S. public as a whole and various demographic groups view President Donald Trump's positions on nuclear weapons. Full Article
science and technology Maxwell Taylor's Cold War: From Berlin to Vietnam By feedproxy.google.com Published On :: May 6, 2020 May 6, 2020Nathaniel Moir reviews Maxwell Taylor's Cold War: From Berlin to Vietnam by Ingo Trauschweizer. Full Article
science and technology Exploring the cost-effectiveness of child dental caries prevention programmes. Are we comparing apples and oranges? By feeds.nature.com Published On :: 2020-03-27 Full Article