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2020 Annual Evaluation Review: ADB’s Project Level Self-Evaluation System

The Annual Evaluation Review (AER) is the flagship report of the Independent Evaluation Department (IED) on the operational performance and results of the Asian Development Bank (ADB). This is an important year for the AER as it marks the first full year of Strategy 2030’s implementation. The AER provides a synthesis of the evaluations prepared by IED in the preceding year, updates performance trends, and draws lessons and offers recommendations to guide ongoing and future operations.




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Effective Approaches to Poverty Reduction: Selected Cases from the Asian Development Bank

This report presents nine case studies on poverty reduction projects financed by ADB in Mongolia, Nepal, the People’s Republic of China, the Philippines, Sri Lanka, Uzbekistan, and Viet Nam.




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Dentons Hong Kong Wins at the <em>IFLR Asia-Pacific Awards</em> 2020 and Recognised at the <em>Asian-mena Counsel: Deals of the Year</em> 2019

Dentons Hong Kong has been recognised for its work at the IFLR Asia-Pacific Awards 2020 and Asian-mena Counsel: Deals of the Year 2019. These recognitions have highlighted the capabilities of the Firm in a wide range of practice areas.



  • Banking and Finance
  • Derivatives and Structured Products
  • Mergers and Acquisitions
  • Hong Kong

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Financing of Tech Startups in Selected Asian Countries

Tech startups rely on an array of financing sources, and venture capital is not a common source.




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Financing of Tech Startups in Selected Asian Countries

Tech startups rely on an array of financing sources, and venture capital is not a common source.




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Entfesselter Sound mit dem JBL® LIVE 300TWS

Kabellose Freiheit verspricht der brandneue JBL LIVE 300TWS! Der neue True Wireless-Kopfhörer sorgt für perfekte Verbindung, glänzt mit seinem stylischen Design und garantiert jederzeit entfesselten Sound ohne Einschränkung. Ausgestattet mit leistungsstarken Treibern liefert der Kopfhörer einen verstärkten Bass, der jede Playlist zum Beben bringt.




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The crowded race of self-driving startups

The race among start ups to win the self driving car billions is heating up and the field is crowded with 75 of them in Silicon Valley alone and more than 240 around the world.




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First self-replicating molecules may have had just two ingredients

A mixture of two carbon-based chemicals can spontaneously form molecules that can copy themselves, hinting at how life may have begun on Earth




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Bacteria sacrifice themselves when under attack to save their colonies

Some bacteria sacrifice themselves when their colony is attacked by rivals, to save their relatives and make sure their shared genes are passed on




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Earth's first life may have fuelled itself with a metal metabolism

The first living organisms had to make essential carbon-based chemicals, and they may have done it by harnessing the chemical power of metals like nickel




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Dazzling damselflies and a SpaceX plume commended by photo awards

An aerial view of crabeater seals in Antarctica, mating damselflies and a twilight rocket launch were among the most lauded entries to the inaugural Nature TTL Photographer of the Year award




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Why Earth's water could be older than Earth itself

How did water survive Earth's searingly hot birth? A radical new answer turns planetary history on its head – and could revolutionise the search for alien life




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Dinosaur extinction lines up closely with timing of volcanic eruptions

Many people assume an asteroid triggered the mass extinction that killed the dinosaurs, but geologists say massive volcanic eruptions occurred at the same time




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Dazzling damselflies and a SpaceX plume commended by photo awards

An aerial view of crabeater seals in Antarctica, mating damselflies and a twilight rocket launch were among the most lauded entries to the inaugural Nature TTL Photographer of the Year award




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FDA commissioner in self-quarantine after exposure to person with COVID-19

U.S. Food and Drug Administration Commissioner Stephen Hahn is in self-quarantine for a couple of weeks after coming into contact with someone who tested positive for COVID-19, an FDA spokesman told Reuters late on Friday.




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Risky Talk review: How to protect yourself from dodgy statistics

Everything from genetic tests to immigration numbers is full of shaky statistics. David Spiegelhalter's new podcast helps separate the factual from the flaky




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How I went from selling MDMA to researching the science of its effects

Christopher Medina-Kirchner used to be a drug dealer. Now he is a researcher looking at their effects, and says society's views on drugs and addiction need updating




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Efforts to stop prisoners reoffending can be useless or even backfire

Efforts to prevent prisoners from reoffending are often lacking in scientific rigour and can even fly in the face of available evidence




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The science of boredom can tell us how to keep ourselves amused

Boredom can be unpleasant, but we can learn from some of the world's dullest people how to keep ourselves amused, says boredom researcher James Danckert




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Can you really grow enough fruit and veg to be self-sufficient?

There's been a surge in people wanting to grow fruit and vegetables, but the path to self-sufficiency isn't as easy as some may have you think, writes James Wong




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Self-driving cars find use in challenging times

After being sidelined as a non-essential business, some self-driving car companies can put their vehicles back on the roads to make food and other deliveries - a win-win scenario that allows them to continue testing their nascent technology.




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With just a canary for company, Russian artist self-isolates in gallery

When an art gallery in southern Russia closed its doors to help curb the spread of the coronavirus, one artist asked to self-isolate there rather than leave his place of work.




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Nintendo smashes Switch sales view; says Animal Crossing is device's fastest-selling game

Japan's Nintendo Co Ltd said on Thursday its fourth-quarter profit soared 200% due to surging demand for its Switch games console, and that title Animal Crossing: New Horizons shifted a record 13.4 million units in its first six weeks.




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Who do you think you are? Why your sense of self is an illusion

Most of us are convinced that we're coherent individuals who are continuous in time. There's just one problem with this sense of self – it can’t exist




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The zombie world of viruses could hold the key to evolution itself

Notorious for making us sick, viruses are weird, undead organisms – but new insights are revealing they may have created life's glorious complexity in the first place




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Harry Potter himself reads...Harry Potter

Daniel Radcliffe joins a slew of celebrities to read Harry Potter at home during lockdown. Emer McCarthy reports.




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I help people who are addicted to the internet wean themselves off

Can you really be addicted to your smartphone? Daria Kuss has shown that it is only a problem for a small number of people - and she knows how to help




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NASA has selected three lunar landers to bring humans to the moon

NASA has awarded $967 million to three space flight companies – Blue Origin, Dynetics and SpaceX – to build lunar landers that will be part of the Artemis programme to send humans to the moon by 2024




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Red light could be used to precisely target rheumatoid arthritis drugs

People with rheumatoid arthritis often take medicines that can have damaging side-effects, but a system that uses red light to deliver drugs exactly where they are needed could help




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Breast Self-Exam Rates Go Up With Counseling

Title: Breast Self-Exam Rates Go Up With Counseling
Category: Health News
Created: 5/1/2009 2:00:00 AM
Last Editorial Review: 5/1/2009 12:00:00 AM




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Selenium Helped Cells 'Reboot' After Exposure to Cancer-Causing Chemicals

Title: Selenium Helped Cells 'Reboot' After Exposure to Cancer-Causing Chemicals
Category: Health News
Created: 4/27/2010 2:10:00 PM
Last Editorial Review: 4/28/2010 12:00:00 AM




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ADHD Drug Ritalin Boosted Self-Control in Tests

Title: ADHD Drug Ritalin Boosted Self-Control in Tests
Category: Health News
Created: 4/25/2014 12:35:00 PM
Last Editorial Review: 4/28/2014 12:00:00 AM




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Teens With History of Self-Poisoning Face Greater Suicide Risk

Title: Teens With History of Self-Poisoning Face Greater Suicide Risk
Category: Health News
Created: 4/25/2015 12:00:00 AM
Last Editorial Review: 4/27/2015 12:00:00 AM




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Childhood Self-Control Linked to Better Job Prospects Later in Life

Title: Childhood Self-Control Linked to Better Job Prospects Later in Life
Category: Health News
Created: 4/24/2015 12:00:00 AM
Last Editorial Review: 4/27/2015 12:00:00 AM




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FDA Proposes Ban on 'Shock' Device Used to Curb Self-Harm

Title: FDA Proposes Ban on 'Shock' Device Used to Curb Self-Harm
Category: Health News
Created: 4/22/2016 12:00:00 AM
Last Editorial Review: 4/25/2016 12:00:00 AM




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Some Smart Yet Easy Ways to Shield Yourself From Skin Cancer

Title: Some Smart Yet Easy Ways to Shield Yourself From Skin Cancer
Category: Health News
Created: 4/28/2016 12:00:00 AM
Last Editorial Review: 4/29/2016 12:00:00 AM




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Teen Suicide Thoughts, Self-Harm Cases Double in a Decade

Title: Teen Suicide Thoughts, Self-Harm Cases Double in a Decade
Category: Health News
Created: 5/4/2017 12:00:00 AM
Last Editorial Review: 5/4/2017 12:00:00 AM




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Striving for Facebook 'Likes' May Not Boost Your Self-Esteem

Title: Striving for Facebook 'Likes' May Not Boost Your Self-Esteem
Category: Health News
Created: 5/3/2017 12:00:00 AM
Last Editorial Review: 5/4/2017 12:00:00 AM




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'Smart Dresser' Might Help Alzheimer's Patients Clothe Themselves

Title: 'Smart Dresser' Might Help Alzheimer's Patients Clothe Themselves
Category: Health News
Created: 5/4/2018 12:00:00 AM
Last Editorial Review: 5/4/2018 12:00:00 AM




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Health Tip: Protect Yourself From Sepsis

Title: Health Tip: Protect Yourself From Sepsis
Category: Health News
Created: 4/30/2019 12:00:00 AM
Last Editorial Review: 4/30/2019 12:00:00 AM




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Burger King to Sell 'Veggie' Whopper Nationwide

Title: Burger King to Sell 'Veggie' Whopper Nationwide
Category: Health News
Created: 4/29/2019 12:00:00 AM
Last Editorial Review: 4/30/2019 12:00:00 AM




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Device Helps Doctors Select Lungs for Transplant

Title: Device Helps Doctors Select Lungs for Transplant
Category: Health News
Created: 4/29/2019 12:00:00 AM
Last Editorial Review: 4/30/2019 12:00:00 AM




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Company Selling Direct-to-Consumer Coronavirus Antibody Test

Title: Company Selling Direct-to-Consumer Coronavirus Antibody Test
Category: Health News
Created: 4/30/2020 12:00:00 AM
Last Editorial Review: 5/1/2020 12:00:00 AM




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Blood Vessels of Obese Teens Age Prematurely

Title: Blood Vessels of Obese Teens Age Prematurely
Category: Health News
Created: 5/7/2020 12:00:00 AM
Last Editorial Review: 5/8/2020 12:00:00 AM




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Updated information on journal selection and participation agreements released

PMC has released expanded information about its selection process for journals that apply for participation. The current review process has been in place since November 2014 and focuses on the scientific rigor and editorial quality of each journal that applies to participate in PMC. Some of the attributes taken into account as part of this process include the article content, journal policies, language quality, and presentation of content. The same assessment considerations are used for reevaluation of currently participating journals. We encourage you to visit the Journal Selection for PMC page to learn more.

Publishers and journals interested in submitting an application to PMC are also encouraged to review our updated policies on agreement types. These policies provide the eligibility criteria for each type of participation agreement and should be considered alongside the pre-application requirements.

We hope these updates are informative and look forward to hearing your feedback.




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Money Not a Good Measure of Your Self-Worth

Title: Money Not a Good Measure of Your Self-Worth
Category: Health News
Created: 4/14/2020 12:00:00 AM
Last Editorial Review: 4/15/2020 12:00:00 AM




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Selected Articles from This Issue




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Two previously unrecorded xiphosurid trace fossils, Selenichnites rossendalensis and Crescentichnus tesiltus, from the Middle Jurassic of Yorkshire, UK

The invertebrate trace fossils Selenichnites rossendalensis and Crescentichnus tesiltus are recorded and described from the Middle Jurassic Gristhorpe Member of the Cloughton Formation of the Cleveland Basin. This is the first record of these ichnospecies from the basin and now completes the occurrence of these and other traces assumed to have been made by limulids from all three non-marine formations of the Ravenscar Group.




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Measuring Oral Health Literacy of Refugees: Associations with Dental Care Utilization and Oral Health Self-Efficacy

Purpose: The purpose of this study was to analyze associations between the oral health literacy of refugees and two oral health outcomes: dental care utilization and oral health self-efficacy.Methods: A convenience sample of refugees in the greater Los Angeles area attending English as a second language (ESL) classes sponsored by two refugee assistance organizations was used for this cross-sectional, correlational study. Participants responded to a questionnaire using items from the Health Literacy in Dentistry (HeLD) scale, in addition to items concerning dental care utilization and oral health self-efficacy. Descriptive statistics, chi-square and Fisher's Exact tests were used to analyze results.Results: Sixty-two refugees volunteered to participate (n=62). A majority of the respondents were female from Iraq or Syria, and selected the item “with little difficulty” for all oral health literacy tasks. In regards to dental care utilization, more than half of the respondents were considered high utilizers (63%, n=34) meaning they had visited a dental office within the last year; while a little more than one-third (37%, n=20), were low utilizers, indicating they had either never been to a dental office or it had been more than one year since they had dental treatment. Statistical analysis showed associations between oral health literacy and dental care utilization. However, few associations between oral health literacy and oral health self-efficacy were identified (p=0.0045).Conclusions: Results support the provision of easily obtainable and understandable oral health information to increase oral health literacy and dental care utilization among refugee populations. Future research is needed to examine the oral health literacy among refugees resettling in the United States.




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Maternal Broadly Neutralizing Antibodies Can Select for Neutralization-Resistant, Infant-Transmitted/Founder HIV Variants

ABSTRACT

Each year, >180,000 infants become infected via mother-to-child transmission (MTCT) of HIV despite the availability of effective maternal antiretroviral treatments, underlining the need for a maternal HIV vaccine. We characterized 224 maternal HIV envelope (Env)-specific IgG monoclonal antibodies (MAbs) from seven nontransmitting and transmitting HIV-infected U.S. and Malawian mothers and examined their neutralization activities against nontransmitted autologous circulating viruses and infant-transmitted founder (infant-T/F) viruses. Only a small subset of maternal viruses, 3 of 72 (4%), were weakly neutralized by maternal linear V3 epitope-specific IgG MAbs, whereas 6 out of 6 (100%) infant-T/F viruses were neutralization resistant to these V3-specific IgG MAbs. We also show that maternal-plasma broadly neutralizing antibody (bNAb) responses targeting the V3 glycan supersite in a transmitting woman may have selected for an N332 V3 glycan neutralization-resistant infant-T/F virus. These data have important implications for bNAb-eliciting vaccines and passively administered bNAbs in the setting of MTCT.

IMPORTANCE Efforts to eliminate MTCT of HIV with antiretroviral therapy (ART) have met little success, with >180,000 infant infections each year worldwide. It is therefore likely that additional immunologic strategies that can synergize with ART will be required to eliminate MTCT of HIV. To this end, understanding the role of maternal HIV Env-specific IgG antibodies in the setting of MTCT is crucial. In this study, we found that maternal-plasma broadly neutralizing antibody (bNAb) responses can select for T/F viruses that initiate infection in infants. We propose that clinical trials testing the efficacy of single bNAb specificities should not include HIV-infected pregnant women, as a single bNAb might select for neutralization-resistant infant-T/F viruses.