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A fluorinated low-molecular-weight PEI/HIF-1α shRNA polyplex system for hemangioma therapy

Biomater. Sci., 2020, 8,2129-2142
DOI: 10.1039/D0BM00171F, Paper
Xiaoshuang Guo, Zihan Yuan, Yang Xu, Minyan Wei, Zhiwei Fang, Wei-En Yuan
RNAi technology targeting HIF-1α could benefit hemangioma therapy effectively and FPEI polyplexes which could inhibit the expression of HIF-1α at the translational level can provide a practicable strategy for clinical hemangioma treatment in the future.
The content of this RSS Feed (c) The Royal Society of Chemistry




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Bacterial nanocellulose as a corneal bandage material: a comparison with amniotic membrane

Biomater. Sci., 2020, Advance Article
DOI: 10.1039/D0BM00083C, Paper
Open Access
Irene Anton-Sales, Justin Christopher D'Antin, Jorge Fernández-Engroba, Victor Charoenrook, Anna Laromaine, Anna Roig, Ralph Michael
Bacterial nanocellulose exhibits valuable properties to act as a corneal bandage material in terms of conformability, suturability, durability and ease of manipulation in ophthalmological environments.
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Delivery of dual miRNA through CD44-targeted mesoporous silica nanoparticles for enhanced and effective triple-negative breast cancer therapy

Biomater. Sci., 2020, Advance Article
DOI: 10.1039/D0BM00015A, Paper
Manisha Ahir, Priyanka Upadhyay, Avijit Ghosh, Sushmita Sarker, Saurav Bhattacharya, Payal Gupta, Swatilekha Ghosh, Sreya Chattopadhyay, Arghya Adhikary
Cationic Mesoporous silica Nanoparticle coated with hyaluronic acid conjugated polymer (HA-Dual miRNA Np) facilitated enhanced dual miRNA loading, efficient delivery and significantly inhibited tumor growth as well as retarded metastasis in triple-negative breast cancer.
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An engineered exosome for delivering sgRNA:Cas9 ribonucleoprotein complex and genome editing in recipient cells

Biomater. Sci., 2020, Advance Article
DOI: 10.1039/D0BM00427H, Paper
Yangyang Ye, Xiang Zhang, Fei Xie, Bin Xu, Ping Xie, Ting Yang, Qian Shi, Chen-Yu Zhang, Yujing Zhang, Jiangning Chen, Xiaohong Jiang, Jing Li
CRISPR-Cas9 components delivered by engineered exosomes achieve genome editing in recipient cells.
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Messenger RNA/polymeric carrier nanoparticles for delivery of heme oxygenase-1 gene in the post-ischemic brain

Biomater. Sci., 2020, Advance Article
DOI: 10.1039/D0BM00076K, Paper
Jungju Oh, Sang-Mi Kim, Eun-Hye Lee, Minkyung Kim, Youngki Lee, Seung Hwan Ko, Ji Hoon Jeong, Chang-Hwan Park, Minhyung Lee
Heme oxygenase-1 messenger RNA (HO1-mRNA) was delivered into the post-ischemic brain, using a polymeric carrier. Therapeutic efficacy of HO1-mRNA delivery was compared with that of HO1-plasmid DNA (HO1-pDNA) in ischemia-reperfusion rat models.
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Dendritic cells reprogrammed by CEA messenger RNA loaded multi-functional silica nanospheres for imaging-guided cancer immunotherapy

Biomater. Sci., 2020, Advance Article
DOI: 10.1039/D0BM00395F, Communication
Yue Hu, Yuyin Tang, Xiao-Jing Zhang, Xiao-Tong Yang, Ying-Ying Tang, Su Li, Linyu Hu, Peng Chen, Dong Zhu
Multi-functional and hierarchically structured silica nanospheres are rationally designed and fabricated, which encapsulate quantum dots to permit near infrared deep tissue imaging and are loaded with carcinoembryonic antigen messenger RNA (CEAmRNA) to enable stable and abundant antigen expression in DCs.
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Serum miRNAs are differentially altered by ethanol and caffeine consumption in rats

Toxicol. Res., 2019, 8,842-849
DOI: 10.1039/C9TX00069K, Paper
M. Martinez, I. M. U. Rossetto, R. M. S. Arantes, F. S. N. Lizarte, L. F. Tirapelli, D. P. C. Tirapelli, L. G. A. Chuffa, F. E. Martinez
Alcoholism is a multifactorial disease with high risk for dependence determined by genetic background, environmental factors and neuroadaptations.
The content of this RSS Feed (c) The Royal Society of Chemistry




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Synergistic antioxidant capacity of CsNPs and CurNPs against cytotoxicity, genotoxicity and pro-inflammatory mediators induced by hydroxyapatite nanoparticles in male rats

Toxicol. Res., 2019, 8,939-952
DOI: 10.1039/C9TX00221A, Paper
Israa F. Mosa, Mokhtar Youssef, Maher Kamel, Osama F. Mosa, Yasser Helmy
Due to their dynamic characteristics, hydroxyapatite nanoparticles (HAP-NPs) have been employed numerous times in nanomedicine and in tissue engineering, particularly as diagnostic and therapeutic agents.
The content of this RSS Feed (c) The Royal Society of Chemistry




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Govt hikes borrowing limit by over 50% to Rs 12 trn as virus grips economy

Sources say the Centre has asked RBI to do whatever to keep yields in check, which may result in massive secondary market bond purchases




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Covid-19 lockdown effect: Every second Indian now on internet in cities

The data released by Nielsen and the Broadcast Audience Research Council (BARC) shows that internet usage has grown sharply in cities over the last one month, touching 54 per cent




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Plasma-assisted filling electron beam lithography for high throughput patterning of large area closed polygon nanostructures

Nanoscale, 2020, Advance Article
DOI: 10.1039/D0NR01032D, Paper
You Sin Tan, Hailong Liu, Qifeng Ruan, Hao Wang, Joel K. W. Yang
The PFEBL process allows enhancement of electron beam writing efficiency for patterning of closed polygon structures using a post-exposure plasma treatment.
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Binding patterns and dynamics of double-stranded DNA on the phosphorene surface

Nanoscale, 2020, 12,9430-9439
DOI: 10.1039/D0NR01403F, Paper
Baoyu Li, Xuejie Xie, Guangxin Duan, Serena H. Chen, Xuan-Yu Meng, Ruhong Zhou
Molecular dynamics simulations and electrophoresis experiments show that dsDNA can form a stable binding on the phosphorene surface through the terminal base pairs and adopt an upright orientation regardless of its initial configurations.
The content of this RSS Feed (c) The Royal Society of Chemistry




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Ternary PtFeCo alloys on graphene with high electrocatalytic activities for methanol oxidation

Nanoscale, 2020, 12,9824-9832
DOI: 10.1039/D0NR00757A, Paper
Hongfei Wang, Kefu Zhang, Jun Qiu, Juan Wu, Jingwen Shao, Huijuan Wang, Yujuan Zhang, Jie Han, Yong Zhang, Lifeng Yan
Ternary PtFeCo alloys as alternatives to conventional Pt electrocatalysts are highly important in the field of the methanol oxidation reaction.
The content of this RSS Feed (c) The Royal Society of Chemistry




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Modulated podosome patterning in osteoclasts by fullerenol nanoparticles disturbs the bone resorption for osteoporosis treatment

Nanoscale, 2020, 12,9359-9365
DOI: 10.1039/D0NR01625J, Communication
Kui Chen, Huan Geng, Wei Liang, Haojun Liang, Yujiao Wang, Jianglong Kong, Jiaxin Zhang, Yuelan Liang, Ziteng Chen, Jiacheng Li, Ya-nan Chang, Juan Li, Gengyan Xing, Gengmei Xing
Fullerenol hampers podosome patterning in osteoclasts, results in the failure of bone resorption.
The content of this RSS Feed (c) The Royal Society of Chemistry




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Fluorescent nanoparticle-based Internet of things

Nanoscale, 2020, 12,9817-9823
DOI: 10.1039/D0NR01365J, Paper
Luca Fichera, Giovanni Li-Destri, Nunzio Tuccitto
The first working molecular-IoT prototype, based on a chemical communication network, was developed by employing three different carbon nanoparticles.
The content of this RSS Feed (c) The Royal Society of Chemistry




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Topological semimetal Li2CrN2 sheet as a promising hydrogen storage material

Nanoscale, 2020, Accepted Manuscript
DOI: 10.1039/D0NR02180F, Paper
Lijuan Ma, Qiang Sun
An ideal electrode for electrochemical storage of hydrogen needs to be conductive for electron. The robust conductivity protected by topology in topological quantum materials just meets this requirement. However, such...
The content of this RSS Feed (c) The Royal Society of Chemistry




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Western Civilization: A Brief History


 

A comprehensive yet concise introduction to Western Civilization, designed to interest and engage contemporary students

Western Civilization: A Brief History is a concise one-volume survey that covers the subject’s ancient origins through to the early 21st century. Stressing social and intellectual history, rather than merely listing names and dates, this stimulating resource offers a more consistent and reader-friendly narrative than traditional textbooks



Read More...




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Hockey veteran Diwan to return from USA

Last month, Diwan had sought help to return from the USA, where he has been stuck because of the travel restrictions in place following the COVID-19 pandemic.




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Max Dare and Ernest Marc oral history interview




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Charles S. Miley Learning Resources Center - Indian River Community College




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ITT Technical Institute Learning Center




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Wilderness Coast Public Libraries




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Home owned by Governor Perry still stands




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Virginia Dare not first white youngun born in U.S!




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Wright architecture marks Florida Southern




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They walk in honor at Florida Southern




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"Tampa Town" was launching pad for Jules Verne




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Pioneer journalists lived in pre-fab house




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History is lost on old fort at New Symrna




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The "little governor" from Arizona founded Tarpon




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Governor's grove a symbol of friendship




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Modern Tallahassee surrounds slave quarters




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"Room & board, $2 --- you furnish meat"




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A great physician was born and died here




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Governor's residence truly an antique




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Fernandina hotel rich in history




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Old governor's home remains in capital




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George Hopson Cornelius




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Vernon W. Evans, Jr




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Walter Norwood Burnside, Jr




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Economic patterns in Hillsborough County in 1997




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Economic patterns in Hillsborough County in 1999




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Interim report on the Greater Tampa regional international trade




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Final report on the Greater Tampa regional international trade




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International trade in Hillsborough County




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Implementation of low impact development in modern urbanization as exampled through capstone design




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International disaster assistance in the Mexico City earthquake




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What we can learn from the February 1992 floods in Ventura County, California




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Learning from risk




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Immediate emotional responses to the Southern California firestorms