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Supporting Biotech Development in Madison

As part of our follow up to our recent Biotech in Wisconsin Meetup about professional development skills, we are asking folks to fill out this poll.




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What is the optimal biotech burn rate?

Ethan Perlstein, founder of Perlstein Lab, asked a question on Twitter and got some great answers from David Grainger, partner at Index Ventures and Katrine Bosley, CEO of Editas Medicine. (You can read the whole thread by clicking through.) @LifeSciVC @sciencescanner @ksbosley @scientre what's the burn rate distribution of biotech NewCos in for the first year of

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Yokogawa Releases SU10 Single Cellome Unit for Use in Biological Research

Yokogawa Electric Corporation (TOKYO: 6841) announces that it has developed the SU10 Single Cellome Unit, a device that uses a nanopipette to inject substances such as genes and drugs and aspirate intracellular materials at target locations in individual cells.




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Climate or biodiversity?




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Compensation between Wnt-driven tumorigenesis and cellular responses to ribosome biogenesis inhibition in the murine intestinal epithelium




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Climate or biodiversity?




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First plant-made biologic approved






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MCU-induced mitochondrial calcium uptake promotes mitochondrial biogenesis and colorectal cancer growth




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MdMYB6 regulates anthocyanin formation in apple both through direct inhibition of the biosynthesis pathway and through substrate removal




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Extra-adrenal glucocorticoid biosynthesis: implications for autoimmune and inflammatory disorders




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Biomimetic niches reveal the minimal cues to trigger apical lumen formation in single hepatocytes




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A high-resolution <i>HLA</i> imputation system for the Taiwanese population: a study of the Taiwan Biobank




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10 years of biosimilars: lessons and trends




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Dissecting reprogramming, differentiation and conversion with network biology




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Profile of a killer: the complex biology powering the coronavirus pandemic




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Statin therapy is associated with lower prevalence of gut microbiota dysbiosis




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TRUPATH, an open-source biosensor platform for interrogating the GPCR transducerome




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Nature Chemical Biology




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Structure of a proton-dependent lipid transporter involved in lipoteichoic acids biosynthesis




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Nature Structural & Molecular Biology




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Single cell and tissue-transcriptomic analysis of murine bladders reveals age- and TNFα-dependent but microbiota-independent tertiary lymphoid tissue formation




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Nature Microbiology




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High-level Postdoctoral research fellow recruitment - The international Joint Center for Biomedical Innovation (JCBI), Henan University : Kaifeng, China

The international Joint Center for Biomedical Innovation (JCBI) is comprised of two partner research nodes using nanoparticle technologies to develop solutions for cancer and neurodegenerative diseases diagnostics. Henan University has established a new research laboratory in nano-bio system innovation and theranostics, with start-up funding and new academic positions. Macquarie’s node is built upon its established excellence in neuroscience and cancer research programs. The collaborative succes…




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Exogenous hormone use, reproductive factors and risk of intrahepatic cholangiocarcinoma among women: results from cohort studies in the Liver Cancer Pooling Project and the UK Biobank




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Molecular profiling of stroma highlights stratifin as a novel biomarker of poor prognosis in pancreatic ductal adenocarcinoma




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Does multiparametric imaging with <sup>18</sup>F-FDG-PET/MRI capture spatial variation in immunohistochemical cancer biomarkers in head and neck squamous cell carcinoma?




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Potential through simplicity: thymidine kinase-1 as a biomarker for CDK4/6 inhibitors




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Viral contamination in biologic manufacture and implications for emerging therapies




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Nature Biotechnology




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Clinical utility of the exosome based ExoDx Prostate(<i>IntelliScore</i>) EPI test in men presenting for initial Biopsy with a PSA 2–10 ng/mL




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Growth of microorganisms in an interfacially driven space bioreactor analog

npj Microgravity, Published online: 08 April 2020; doi:10.1038/s41526-020-0101-4

Growth of microorganisms in an interfacially driven space bioreactor analog




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Ex situ determination of freely dissolved concentrations of hydrophobic organic chemicals in sediments and soils: basis for interpreting toxicity and assessing bioavailability, risks and remediation necessity




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Nature Cell Biology




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MicroRNA binding site polymorphism in inflammatory genes associated with colorectal cancer: literature review and bioinformatics analysis




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TMB: a promising immune-response biomarker, and potential spearhead in advancing targeted therapy trials




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Microbiota and colorectal cancer: colibactin makes its mark




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A roadmap for development of neuro-oscillations as translational biomarkers for treatment development in neuropsychopharmacology




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Multilevel omics for the discovery of biomarkers and therapeutic targets for stroke




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An update on blood-based biomarkers for non-Alzheimer neurodegenerative disorders




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NLRP3 inflammasome activity as biomarker for primary progressive multiple sclerosis




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Mining bacteria for biosensors




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Possible consequences of the COVID-19 pandemic on the use of biospecimens from cancer biobanks for research in academia and bioindustry




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Bioinformatic prediction of potential T cell epitopes for SARS-Cov-2




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Implication of gut microbiota in the association between infant antibiotic exposure and childhood obesity and adiposity accumulation




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Biomedical ethics 2.0: redefining the meaning of disease, patient and treatment




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Mechanisms governing autophagosome biogenesis




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Nature Reviews Molecular Cell Biology




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Kidney dendritic cells: fundamental biology and functional roles in health and disease