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'1917' dominates our 2020 Oscar predictions, but 'Parasite' could surprise

Predicting the four acting races for the 2020 Oscars is easy this year, but there's still drama in the best picture race and others




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'Parasite' director Bong Joon Ho makes Oscars history with win

A historic best director Oscar goes to 'Parasite' filmmaker Bong Joon Ho, the first Korean winner and only the second time the prize has gone to a film not in English.




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How 'Parasite' made Oscars history as the first foreign-language best picture winner

"Parasite" won the Oscar for best picture, becoming the first non-English language movie to do so. How did it win?




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It's just the Oscars — but my God, it matters that 'Parasite' won best picture

With "Parasite," the academy gave best picture to the actual best picture. It also made history.




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Audience demands 'Parasite' team gets to finish Oscars speech

When the Oscars telecast tried to cut off the "Parasite" team's speech after winning best picture, the audience rallied to let them continue.




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Ava DuVernay, Sandra Oh and others celebrate 'Parasite's' historic Oscar win

Ava DuVernay, Olivia Munn and Jon M. Chu were among the celebs celebrating "Parasite's" historic win for best picture at the 2020 Oscars.




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Bong Joon Ho's wife couldn't stop crying during 'Parasite's' big Oscars night

"Parasite" won four Oscars, including best picture, and emotions ran high among the film's supporters, particularly for director Bong Joon Ho's wife.




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Column: Netflix didn't win best picture, but 'Parasite' couldn't have triumphed at the Oscars without it

More than film critics or a more international film academy, Netflix has proved that subtitles are a bridge, not a barrier.




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From '1917' to, yes, 'Parasite,' video games are even influencing prestige movies

Oscar's big winner, 'Parasite,' and war tale '1917' show how interactive entertainment is shaping linear storytelling — often for the better.




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Feedback: From 'Parasite's' win to In Memoriam snubs, readers sound off on this year's Oscars

Feelings about Oscar "In Memoriam" snubs from Luke Perry to "Lolita's" Sue Lyon, plus the best picture win for "Parasite," Kirk Douglas remembrances and lingering thoughts about Shakira and Jennifer Lopez at the Super Bowl.




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Tesla tiene un incentivo enorme para desplegar la tecnología de conducción autonoma. ¿Pero está el mundo listo?

Elon Musk tiene un gran incentivo financiero para activar la conducción de servicio completo. ¿Pero está Tesla cerca de estar listo?




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Maldives holidays: Why you’ll never be bored at paradise resort Kandima Maldives



MALDIVES holidays are on the bucket list of so many Britons thanks to the picture postcard-worthy scenery and year-round sun. Kandima Maldives is one of many hotels in the Indian Ocean nation, so what makes it stand out? This writer headed to the resort to find out.




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Pirates of the Caribbean 6 ‘is SEPARATE’ to potential female spin-off: TWO movies possible



PIRATES OF THE CARIBBEAN 6 is separate to a possible female-led spin-off, according to a Disney insider. We could be looking at two movies with Johnny Depp's Jack Sparrow returning.




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ML 3.5 OFFSHORE VALPARAISO, CHILE

Magnitude  ML 3.5
Region  OFFSHORE VALPARAISO, CHILE
Date time  2020-05-09 15:12:07.0 UTC
Location  32.29 S ; 71.75 W
Depth  34 km




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Indianapolis police officers arrested in separate incidents unrelated to this week's shooting

Two Indianapolis police officers have been arrested in separate and unrelated incidents.

       




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Noblesville teachers parade through students' neighborhoods: 'We've missed them terribly'

Teachers from North Elementary School in Noblesville decorated their cars and paraded through neighborhoods, waving and honking at students from afar during the closure of schools because of the coronavirus outbreak.

      




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Waving and honking hello: Noblesville teachers have car parade to see students

In less than 24 hours, teachers organized a parade of nearly 40 cars to say hello to students from afar.

      




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Coronavírus: por que alguns pacientes já recuperados voltam a ter teste positivo para covid-19, segundo OMS

Infectologista da organização explica que células mortas expelidas do pulmão fazem exames darem positivo mais de uma vez — mas não necessariamente quer dizer que a pessoa voltou a ficar infectada pelo coronavírus.




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O sul-coreano que dá abrigo e aula em casa para 10 meninos que fugiram da Coreia do Norte

Kim Tae- hoon, de 45 anos, cuida de 10 meninos norte-coreanos que desertaram do regime repressivo de Pyongyang sem seus pais; o mais novo tem apenas 10 anos e o mais velho, 22.




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Coronavírus: 'Países vão ter que se endividar para salvar o emprego e a vida das pessoas', diz presidente do BID

Para Luis Alberto Moreno, pandemia deixou ainda mais evidente a desigualdade da América Latina e mostrou necessidade de se investir na saúde pública regional.




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Quanto tempo uma pessoa leva para se recuperar da covid-19

Recuperação pode ser um processo lento, dependendo da gravidade do quadro.




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Coronavírus: pais deveriam interromper trabalho em casa para dar atenção a filhos na quarentena, diz especialista em infância

Apesar de serem menos afetadas pelo coronavírus, crianças são as que podem sofrer maiores efeitos sobre sua saúde no longo prazo, explica pesquisador americano Philip Fisher.




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Mortes, testes e contágio: como o Brasil se compara a outros países na pandemia de coronavírus

BBC News Brasil apresenta situação do país no cenário internacional a partir de cinco dados: taxa de espalhamento da doença, taxa de morte por 1 milhão de habitantes, taxa de teste por mil habitantes, o número de dias que leva para dobrar o total de casos registrados e a previsão do PIB (soma de todas as riquezas produzidas) em 2020 e 2021.




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Dubrovnik, a cidade medieval planejada para a quarentena

Os ‘lazarettos’ de Dubrovnik são a memória da luta da cidade no combate a doenças infecciosas séculos atrás.




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'Se encontrá-las, corra e nos chame!': cientistas nos EUA alertam para chegada de 'vespas assassinas'

Segundo estudos, insetos liberam toxina tão potente que pode causar a morte de uma pessoa que tiver levado várias picadas.




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A descoberta nas fontes termais de Yellowstone, nos EUA, que se tornou chave para os testes da covid-19

Há meio século, Thomas Brock descobriu uma bactéria capaz de sobreviver a altas temperaturas; saiba como essa descoberta cruza com o combate à pandemia do novo coronavírus.




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Fim da quarentena do coronavírus: o que são as 'bolhas sociais', estratégia para o fim do isolamento adotada pela Nova Zelândia e outros países

Um dos países de maior sucesso na luta contra a covid-19, a Nova Zelândia permitiu que seus cidadãos expandissem, de forma limitada, o círculo de contatos; entenda como essa proposta funciona e por que está sendo avaliada por vários governos.




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Diretor da PF foi trocado para garantir mudança de chefia no RJ, diz Moro em depoimento

'Você tem 27 Superintendências, eu quero apenas uma, a do Rio de Janeiro', teria dito Bolsonaro a Moro. Primeira ação do novo diretor-geral da PF foi trocar comando no Rio.




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Fila para UTI e falta de testes: os relatos do colapso na saúde que leva o Rio a planejar lockdown

Profissionais de enfermagem relatam falta de equipamentos de proteção, baixas nas equipes e lotação; em ofício, governador Witzel reconhece que esforços contra a covid-19 não foram suficientes e que estuda endurecer confinamento.




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'Não quero morrer sem revê-la': as mães que doaram seus filhos no passado e hoje lutam para reencontrá-los

Mulheres que doaram os filhos décadas atrás relatam angústia e tristeza em busca de respostas sobre paradeiros das crianças.




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Banking parallels

Nationalising a bank is a big deal. But it is not unprecedented. It is worth reading the history of Continental Illinois, nationalised by the US Federal Deposit Insurance Corporation in 1984. You can get the full story from the FDIC...



  • Notes on Real Life

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IU soccer coach believes culture will continue through separation

Todd Yeagley is confident his players will carry out workouts and improve despite not being able to practice together.

       




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5 ways Paramore mixed past and present at the Lawn

Paramore played the Farm Bureau Insurance Lawn at White River State Park Sunday, July 1. Here's a recap.

      




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Hayley Williams leads Paramore's electric performance at White River

       




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Wander Women St. Pete Recap Part II: Stand Up Paddle to Paradise

Where we’re at: I’m recapping my travels in 2019, including this retreat to Florida in July. There are more details about our upcoming 2020 retreats at the end of this post. I realize for some this is a difficult time to read about travel. I am writing often about our current global crisis — the impact it’s […]
 




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Indianapolis police officers arrested in separate incidents unrelated to this week's shooting

Two Indianapolis police officers have been arrested in separate and unrelated incidents.

       




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Timeline: Paraguay

Key facts, figures and dates




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Country profile: Paraguay

Key facts, figures and dates




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For many immigrants, family separation happens long before the border

Review of 'A Good Provider Is One Who Leaves: One Family and Migration in the 21st Century' by Jason DeParle




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The unreasonable importance of data preparation

In a world focused on buzzword-driven models and algorithms, you’d be forgiven for forgetting about the unreasonable importance of data preparation and quality: your models are only as good as the data you feed them. This is the garbage in, garbage out principle: flawed data going in leads to flawed results, algorithms, and business decisions. […]




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Article: Will Blockchain Blow Up Digital Advertising Paradigms?

Ian McKee, founder and CEO of Singapore-based Vuulr, explains the value of blockchain technology—and the threat it poses to the structure of traditional digital advertising.




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Video: Stars' Oscar preparations

Part of the Going for gold promo for the BBC UK Homepage




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Zinc promotes liquid-liquid phase separation of tau protein [Protein Structure and Folding]

Tau is a microtubule-associated protein that plays a major role in Alzheimer's disease (AD) and other tauopathies. Recent reports indicate that, in the presence of crowding agents, tau can undergo liquid–liquid phase separation (LLPS), forming highly dynamic liquid droplets. Here, using recombinantly expressed proteins, turbidimetry, fluorescence microscopy imaging, and fluorescence recovery after photobleaching (FRAP) assays, we show that the divalent transition metal zinc strongly promotes this process, shifting the equilibrium phase boundary to lower protein or crowding agent concentrations. We observed no tau LLPS-promoting effect for any other divalent transition metal ions tested, including Mn2+, Fe2+, Co2+, Ni2+, and Cu2+. We also demonstrate that multiple zinc-binding sites on tau are involved in the LLPS-promoting effect and provide insights into the mechanism of this process. Zinc concentration is highly elevated in AD brains, and this metal ion is believed to be an important player in the pathogenesis of this disease. Thus, the present findings bring a new dimension to understanding the relationship between zinc homeostasis and the pathogenic process in AD and related neurodegenerative disorders.




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The Human Plasma Proteome: A Nonredundant List Developed by Combination of Four Separate Sources

N. Leigh Anderson
Apr 1, 2004; 3:311-326
Research




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Parallel Reaction Monitoring for High Resolution and High Mass Accuracy Quantitative, Targeted Proteomics

Amelia C. Peterson
Nov 1, 2012; 11:1475-1488
Technological Innovation and Resources




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Comparative Proteomic Analysis of Eleven Common Cell Lines Reveals Ubiquitous but Varying Expression of Most Proteins

Tamar Geiger
Mar 1, 2012; 11:M111.014050-M111.014050
Special Issue: Prospects in Space and Time




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The Paragon Algorithm, a Next Generation Search Engine That Uses Sequence Temperature Values and Feature Probabilities to Identify Peptides from Tandem Mass Spectra

Ignat V. Shilov
Sep 1, 2007; 6:1638-1655
Technology




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Absolute Quantification of Proteins by LCMSE: A Virtue of Parallel ms Acquisition

Jeffrey C. Silva
Jan 1, 2006; 5:144-156
Research




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Wartime paradigms and the future of western military power

4 March 2020 , Volume 96, Number 2

Olivier Schmitt

From the perception of the imminence of threats at the political level to the seizing of initiative through proper timing at the tactical level, temporality is directly related to war and warfare. Yet, despite some analyses of the importance of time at the political/grand strategic level (usually by scholars) and at the tactical level (usually by military professionals) there is surprisingly little discussion of the impact of time on the preparation and the conduct of warfare. This article introduces the concept of ‘wartime paradigm’ as a heuristic device to understand the relationship between the perception of time and the conduct of warfare, and argues that after the Cold War, a specific ‘wartime paradigm’ combining an optimization for speed and an understanding of war as risk management has guided western warfare, from force structure to the conduct of actual operations. It shows how the changing character of warfare directly challenges this wartime paradigm and why, if western forces want to prevail in future conflicts, the establishment of a new wartime paradigm guiding technological improvements and operational concepts is critical.




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A simplified method for the preparation of detergent-free lipid rafts

Jennifer L. Macdonald
May 1, 2005; 46:1061-1067
Methods